Genetics

Question 1

What is the backbone of DNA?

Answer 1

2-deoxyribose

Question 2

How is DNA arranged?

Answer 2

Two strands bound in an anti-parallel molecule

Question 3

What does thymine pair with?

Answer 3

Adenine

Question 4

What does guanine pair with?

Answer 4

Cytosine

Question 5

During which phase of the cell cycle does DNA replication happen?

Answer 5

S phase

Question 6

What is mitosis?

Answer 6

When one diploid parent cell divides into two diploid daughter cells

Question 7

What is meiosis?

Answer 7

When one diploid parent cell becomes 4 haploid daughter cells

Question 8

What is the backbone of RNA?

Answer 8

Ribose

Question 9

What is DNA transcribe to?

Answer 9

pre-mRNA

Question 10

What is pre-mRNA spliced to?

Answer 10

mRNA

Question 11

What happens to mRNA?

Answer 11

Translated into protein

Question 12

What is a polymorphism?

Answer 12

Any variation in the human genome that has a population freq >1%
(does not cause disease)

Question 13

What is a mutation?

Answer 13

Gene change which causes disease

Question 14

What is aneuploidy?

Answer 14

Whole extra/missing chromosome

Question 15

What is a Robertsonian translocation?

Answer 15

Two acrocentric chromosome stuck end to end

Question 16

aCGH looks at a specific part of the genome

true/false

Answer 16

False

looks at whole genome

Question 17

What does karyotyping screen for?

Answer 17

Balanced rearragenements

Question 18

What does aCGH screen for?

Answer 18

Deletions/duplications