Genetics Flashcards

(37 cards)

1
Q

Sexual reproduction definition

A

When genetic information is combined from two organisms to produce genetically-different offspring

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2
Q

Fertilisation method

A

Male gamete fuses with female gamete to make a soy gore
Zygote contains full set of chromosomes
Zygote undergoes cell division and becomes an embryo
Embryo inherits characteristic from both parents as it is a mixture of chromosomes from both parents

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3
Q

Meiosis method

A

It duplicates its DNA
Chromosomes line up in centre of cell
Chromosomes in each pair came from both parents of organism
Chromosomes are pulled apart so new daughter cells contain only one copy of each chromosome
This creates genetic variation in the offspring (as each cell has a mixture of mother’s and father’s chromosomes)
The chromosomes line up again in both daughter cells and undergo mitosis, creating 4 daughter cells

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4
Q

Sexual reproduction advantages

A

Creates genetic variation in a population (so at least some individuals will survive when environment changes)
Leads to natural selection and evolution as species become better adapted to their environment

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5
Q

Sexual reproduction disadvantages

A

Takes time and energy (so less offspring)

Two parents are required

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6
Q

Asexual reproduction advantages

A

Produces lots of offspring quickly (so colonises an area quickly)
Only one parent is needed so can reproduce anytime

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7
Q

Asexual reproduction disadvantages

A

No genetic variation between offspring in population (so whole population will be affected from environmental change)

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8
Q

All bases in DNA

A

Adenine
Thymine
Cytosine
Guanine

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9
Q

Shape of DNA

A

Double helix

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10
Q

DNA molecule structure

A

Made up of nucleotides
Nucleotides made up of pentose sugar, phosphate backbone and base
Complementary base pairs are connected by weak hydrogen bonds

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11
Q

Chromosomes definition

A

Long coiled-up molecules of DNA

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12
Q

Gene definition

A

Section of DNA that codes for a particular protein

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13
Q

Extracting DNA from fruit cells method

A

Mash strawberries or kiwi and put them in a beaker containing detergent and salt
Detergent will break down cell membranes (releasing them)
Salt will make DNA stick together
Filter mixture to get froth and insoluble bits of cell out
Gently add ice-cold alcohol to filtered mixture
DNA will come out of mixture as insoluble in cold alcohol
Fish DNA out with glass rod

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14
Q

What controls protein synthesis in a cell?

A

DNA

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15
Q

Protein definition

A

Chains of amino acids that controls a function in the body

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16
Q

Base triplet definition

A

Sequence of three bases that decides what amino acid is used in that turn in a gene

17
Q

Mutation definition

A

Rare, random change to an organism’s base sequence that can be inherited

18
Q

Transcription method

A

RNA polymerase binds region of non-coding DNA in front of gene
2 DNA strands unzip and RNA polymerase moves along one of strands of DNA
It uses coding DNA in the gene as template and makes mRNA and ensures DNA and RNA base pairs are complementary
It moved out of the nucleus and joins with a ribosome

19
Q

What replaces thymine in messenger RNA?

20
Q

mRNA structure

A

polymer of nucleotides that’s shorter than DNA and only single-stranded

21
Q

RNA polymerase definition

A

Enzyme involved in joining together RNA nucleotides to make mRNA

22
Q

Why is transcription required?

A

DNA in the cell nucleus is too large to move out of the nucleus

23
Q

Translation method

A

Order and what amino acid is brought is decided by codons in mRNA
tRNA with complementary anticodon to codons of mRNA brings amino acids in correct order
Amino acids are joined together by ribosome, making a polypeptide chain (protein)

24
Q

Role of non-coding DNA in protein synthesis

A

RNA polymerase needs to bind to a region of non-coding DNA in front of a gene

25
Mendel experiment
Mendel crossed two pea plants of different heights Offspring were all tall Mendel crossed all tall offspring together Tall:short ratio of offspring was 3:1
26
Mendel experiment conclusions
Characteristics were determined by alleles Alleles were passed on to offspring from each parent Alleles could be dominant or recessive (1 or more dominant = expressed, All recessive = expressed)
27
Why are men more susceptible to sex-linked disorders?
Men only have 1 X chromosome and so only need 1 faulty allele in X chromosome (no copy in Y chromosome) to have disorder
28
Heterozygous definition
2 different alleles for a gene
29
Homozygous definition
Same alleles for one gene
30
Phenotype definition
Characteristic that is shown by alleles
31
Genotype definition
What alleles are present in a gene
32
What blood types are dominant and will make a cosmonaut allele?
I(A), I(B)
33
What was the Human Genome Project?
Project that started in 1990 A compete map was made of human genome in 2003 contains around 20,500 genes Around 1800 genes have been found linked to disease
34
Prediction and prevention of diseases due to HGP
doctors could give tailored advice if they knew how common diseases interacted with genes doctors could check us regularly to ensure early treatment to diseases we may be susceptible to
35
Testing and treatment for inherited disorders due to HGP
Doctors can identify genetic disorders we may have due to our alleles Scientists can now quickly find genes and alleles linked with disorders
36
New and better medicines due to HGP
Some genetic variations have been identified to affect medicine e.g. dosage Scientists can tailor medicine to work on people with particular genes In the future, we can make more effective treatments with less side effects if we know how the disease affects us on a molecular level
37
Drawbacks of HGP
increased worry from minor symptoms Pressure of not having children due to genetic problems Prejudice against employing people with serious genetic diseases