Genetics and Variation Flashcards
What are the four stages of cell eukaryotic cell division?
Prophase, metaphase, anaphase, telophase
What is chromatin
The unravelled form of chromosomes
What is a chromosome?
A long DNA molecule associated with another protein (usually a histone protein)
How many centromeres in one chromosome?
1
What is a homologous pair of chromosomes?
Unidentical chromosomes with DNA that codes for the same features in the same place.
What are the 4 stages of the cell cycle (not PMAT) and what do they stand for?
G1,growth phase 1
S, synthesis phase
G2, growth phase
M, mitosis
What happens in the four stages of the cell cycle (G1, S, G2, M)
G1- cell grows, normal processes occur
S- chromatids replicate
G2- cells build up ATP, DNA is screened
M- PMAT
What are the 4 stages of mitosis
Prophase
Metaphase
Anaphase
Telophase
What happens in Prophase? (4)
1- chromosomes condense
2- centromeres move to poles
3- spindle fibres form
4- nuclear envelope breaks down
What happens in Metaphase? (3)
1- centrosomes arrive at opposite poles
2-chromosomes line up at equator
3- spindle fibres attach to centromeres
What happens in Anaphase? (2)
1- sister chromatids separate at centromere
2- spindle pulls chromatids to opposite ends of cell
What happens in Telophase?(3)
1- chromosomes decondense back into chromatin
2- nuclear envelope & nucleolus reform
3- spindle breaks down
What happens after Mitosis? (Name and what actually happens)
Cytokinesis, the cytoplasm divides
What controls cell division?
Proteins called cyclins
What controls cell division?
Proteins called cyclins
What type of tumour does not lead to cancer?
Benign tumours
How do malignant tumours spread?
Through blood or lymph vessels
What is the process of a tumours spreading called, and what type of tumour is formed?
Metastasis forms a metastatic tumour
What three ways can tumours cause damage?
Pinch blood vessels
Outcompete organs for nutrients
Damage organs
How do prokaryotes divide (name)
Binary fission
What is the process of binary fission?
DNA replicates
Plasmids replicate ( more than once)
Cytoplasm divides
How does viral replication work?
(4)
Attachment proteins attach to host cell surface markers
Virus injects nucleus acid into host cell
The host cells ribosomes produce new viral particles
Virus is released through budding or bursting
How do viruses cause damage?
Reduce/ inhibit normal cell function
What two enzymes do viruses contain and what do the enzymes do?
Reverse transcriptase converts RNA into DNA to be inserted into genome
Integrate inserts viral DNA into host cells genome