Genetics II - Population Genetics Flashcards

1
Q

Define allele

A

A single copy of a gene

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2
Q

Define genotype

A

The pair of alleles in an individual

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3
Q

Define polygenic traits?

A

Characteristics influenced by more than one gene

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4
Q

Define gene interaction

A

A single trait controlled by 2 or more genes
- each of which has multiple alleles within a population of individuals.

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5
Q

Define monomorphic gene

A

A gene which exists as a single allele in a population
- so all individuals are automatically homozygous for it as the 2 copies are the same.

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6
Q

Define polymorphic gene

A

A gene that has 2 or more allelic variants within a population
- homozygous: both copies same
- heterozygous: copies differ

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7
Q

What is population genetics?

A

Study of genes and genotypes in a population

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8
Q

Define gene pool

A

All of the alleles for every gene in a given population

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9
Q

What are single nucleotide polymorphisms (SNPs)?

A

Smallest type of genetic change in a gene

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10
Q

How do you calculate allele frequency?

A

(no. of copies of a specific allele in a population) / (total number if all alleles for that gene in a population)

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11
Q

How do you calculate genotype frequency?

A

(no. of individuals with a particular genotype in a population) / (total number of individuals in a population)

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12
Q

What is the Hardy-Weinberg equation?

A

Sums all genotype frequencies for a given gene in a population.

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13
Q

What is the mathematical Hardy-Weinberg equation?

A

p^2 + 2pq + q^2 = 1

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14
Q

What does the Hardy-Weinberg law state?

A

That allele and genotype frequencies in population will remain constant from generation to generation in the absense of other evolutionary influences.

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15
Q

What are the conditions for Hardy-Weinberg Equilibrium?

A
  • no new mutations occur
  • no natural selection occurs
  • pop so large that allele frequencies do not change due to random sampling error
  • no migration changes between diff pops
  • random mating occurs
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16
Q

Do any populations meet the conditions for Hardy-Weinberg Equilibrium?

A

None so an evolution mechanism is at work

17
Q

Define Microevolution

A

Changes in a population’s gene pool from generation to generation

18
Q

Give examples of genetic variation

A
  • mutations
  • gene duplication
  • horizontal gene transfer
19
Q

Why do microevolutionary changes occur?

A
  • new genetic variation produced
  • actions of evolutionary mechanisms that alter the prevalence of an allele/genotype
20
Q

Give examples of evolutionary mechanisms

A
  • natural selection
  • random genetic drift
  • migration
  • non-random mating
21
Q

How does natural selection contribute as an evolutionary mechanism?

A

Results in changes in populations of living organisms that promote their survival and reproduction in a particular environment - resulting in adaptation.