GI Flashcards

1
Q

List 3 signs which may be elicited on abdominal examination of this patient.

A

Tinkling bowel sounds
Hyperresonant bowel
Abdominal distension

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2
Q

UC signs may seen in a patient

A

Uveitis/episcleritis, arthritis/arthralgia, pyoderma gangrenosum/erythema
nodosum, mouth ulcers

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3
Q

1st line for UC

A

5 – Amino-Salicylates (e.g. sulfasalazine, mesalazine)

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4
Q

Diagnostic for Pancreatic cancer

A

Protocol CT pancreas

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5
Q

Stroking the inside of his thigh results in no elevation of the affected testis.
Elevation of both his testes relieves none of his pain too. What are these 2 signs known as?

A

Negative cremasteric reflex (1) and negative Phren’s sign

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6
Q

Suggest 4 complications of CKD.

A

Anaemia, Osteodystrophy (e.g., osteoporosis), CVD, Encephalopathy/Neuropathy

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7
Q

Liver role

A
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8
Q

H.Pylori pathogenesis

A

Helicobacter pylori has 2 main mechanisms to survive in the acidic gastric environment:
- chemotaxis away from low pH areas, using its flagella to burrow into the mucous lining to reach the epithelial cells underneath
- secretes urease → urea converted to NH3 → alkalinization of acidic environment → increased bacterial survival

Pathogenesis mechanism:
Helicobacter pylori releases bacterial cytotoxins (e.g. CagA toxin) → disruption of gastric mucosa

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9
Q

What do you classify stool

A

Bristol Stool Chart

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10
Q

If terlipressen is contraindicated for Oesphageal varices what should be used instead ?

A

IV somatostatin

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11
Q

what cytoplasmic inclusion would you see in hepatocytes in patients with alcoholic hepatitis?

A

Mallory bodies

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12
Q

What two pathological factors contribute to the formation of ascites?

A

High portal venous pressure
Low serum albumin

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13
Q

Name 3 complications of diverticulosis?

A

Haemorrhage
Peritonitis
Perforation
Fistulae
Abscess
Post-infective strictures

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14
Q

Which of the following is not an
obstructive cause of dysphagia?
A. Pharyngeal carcinoma
B. Oesophageal web
C. Retrosternal goitre
D. Peptic stricture
E. Achalasia

A

Achalasia

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15
Q

Duodenal Ulcers symptoms improve before/after meals

A

after meals

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16
Q

Best diagnoses for hiatus hernia

A

Barium meal

17
Q

What are the most common cause of upper GI bleed

A

Peptic ucers

18
Q

Which of the following
medications would act as prophylaxis in preventing a rebleed from his oesophageal
varices?

A

Propanolol

19
Q

Lower/Raised MCV for alcoholic related liver disease

A

Raised MCV

20
Q

CKD treatment

A

Prednisolone

21
Q

Where is Vitamin B12 absorbed

A

Terminal ileum

22
Q

Test for cirrhosis regarding alpha 1 antitrypsin

A

Liver Biopsy which shows cirrhosis and positve Acid Schiff globules

23
Q

Test for lung disease regarding alpha 1 anitrypsin

A

High resoltion CT thorax

24
Q

Management for Wilsons disease

A

Pencillamine
Trientene
Copper Chelation

25
Q

Anti spasmodics medication

A

Hyoscine butylbromide (Buscopan)
Mebeverine

26
Q

Specialsit laxatives used for IBS

A

Linaclotide

27
Q

Viral causes of gastententeritis

A

Norovirus
Rotavirus

28
Q

G.S for Crohn’s

A

Endoscopy +/- biopsy

29
Q

Crohn’s management

A

INDUCING REMISSION
First line: Steroids (e.g. oral prednisolone or IV hydrocortisone)

2nd:Azathioprine
Mercaptopurine
Methotrexate
Infliximab
Adalimumab

MAINTAINING

1st Line:
Azathioprine
Mercaptopurine

30
Q

UC management

A
31
Q

Test used to confirm CLL

A

Immunophenotyping

32
Q

CLL treatment

A

Radio
Chemo
Stem Cell

At risk of neutropenic sepsis/sepsis

33
Q

C.difficile what is it?

A

anaerobic gram-positive, spore-forming, toxin-producing bacillus

34
Q

What does Hpylori stain with

A

Silver Stain

35
Q

Diabetes type one gene + hypersenstivity reaction

A

4
HLA DR3 + 4