GI Bacteria: Colonization (+/- toxin) mediated Flashcards Preview

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Flashcards in GI Bacteria: Colonization (+/- toxin) mediated Deck (32):
1

Epi of Salmonella (non typhoidal)

-Contaminated animal products e.g. meat/eggs
-Reptiles
-10% food borne illness USA

2

Epi of Salmonella (typhoidal)

human-human evolution; human feces/carriers

3

Epi of Shigella

Human-human fecal oral (4 Fs); High infectivity; daycare centers

4

Yersinia Epi (3)

Animal hosts (rodents, pets, etc; contaminated pork/beef; anemia and infants high risk

5

contaminated animal product (POULTRY, milk)
10-15% food poisoning in USA

Campy Epi

6

H Pylori EPi

person to person saliva

7

EHEC

Ground beef, cattle refuse: water, radishes, spinach, apple juice

8

uncooked foods (salad fruits); childhood diarrhea developing countries

ETEC

9

B. Cereus

Fried rice is risk for emetic form. Cream milk sauce is risk for diarrheal form.

10

Listeria

cheeses, milk, veggies. Pregnant mothers, immunocompromised, neonates

11

Vibrio

contaminated water/seafood/fish

12

ddx for acute bloody diarrhea in bacterial setting

EHEC (starts watery)
EIEC
Campy
Shigella
Salmonella (non-typhoidal)
Yersinia Entercolitica
C. diff (possibly)

13

List bacteria that are invasive and could result in bloody stools

Salmonella
Campy
Shigella
Yersinia
EIEC (similar but milder bloody diarrhea than shigellosis)
Vibrio (not bloody)

14

invades terminal ileum and stops in lamina propria

non typhoidal salmonella

15

invades intestinal epithelium and causes ulceration/bleeding of mucosa

campy

16

shigella entry

invades m cells and lyses phagosome

17

sort salmonella (both forms), shigella, vibrio (all forms), e coli (EPEC, EHEC, EAEC, DAEC, EIEC) as intracellular or extracellular

all intracellular except for vibrio cholerae and EPEC, EHEC, ETEC, EAEC, DAEC. Vib Vuln is either or.

18

travelers diarrhea

ETEC or EAEC

19

infants can get this form of E Coli

EPEC

20

describe clinical presentation of typhoidal salmonella

malaise, fever, headache, myalgia, ROSE SPOT, constipation

21

describe clinical presentation of EPEC

copious watery mucoid infant diarrhea everywhere

22

describe clinical presentation of ETEC

travelers diarrhea (watery, profuse). Also, infant diarrhea in developing countries.

23

describe clinical presentation of shigella

abd cramps, TENESMUS, frequent scant bloody stools with pus, fever. Can be just watery diarrhea, OR start out watery and progress.

24

describe clinical presentation of yersinia

bloody diarrhea, mesenteric lymphadenitis

25

describe clinical presentation of campy

diarrhea (bloody), fever, abd pain. Can have GBS or Reiters too.

26

describe clinical presentation of Salmonella (both types)

Salmonella non typhoidal: NV, abd cramping, non bloody diarrhea x3-4 days, +/- bloody diarrhea, fever, septicemia, meningitis, osteomyelitis;

Salmonella typhoidal: fever malaise constipation myalgia, headache, ROSE SPOTS, +/- GI hemmorhage, perf, metastatic spread, colonize GB

27

name 8 causes of acute non inflammatory diarrhea (bacteria +virus +protozoa)

virus: rotavirus, norovirus
protozoa: giardia, cryptosporidium
Bacteria: staph aureus(?), vibrio cholerae, ETEC, bacillus cereus

28

name 9 cases of acute inflammatory diarrhea (bacteria +virus+protozoa)

virus: cmv
protozoa: entamoeba histolytica, schistosomiasis
bacteria: campy, salmonella, shigella, ehec, c. diff, yersinia

29

is small bowel mostly the target for inflammatory or non inflammatory diarrhea?

non inflammatory (exception: salmonella more often in small bowel)

30

which conditions require abx therapy (5) (bacteria and protozoa)

shigella, salmonella, c diff, giardia, e histolytica

31

what can you use for inflammatory diarrhea in terms of antimotility?

bismuth subsalicylate

32

name infectious and inflammatory (but still infectious) causes of chronic diarrhea

v cholera, ETEC, whipple disease, c. diff, yersinia, cmv, e histolytica