GI drugs Flashcards
(5 cards)
1
Q
What are examples of 3 common drugs
A
PPI - omeprazole
H2 antagonist - ranitadine
Antacid - gaviscon
2
Q
How are peptic ulcers treated
A
PPI -> H2 antagonist
3
Q
How is GORD treated
A
PPI -> H2 antagonist
Antacid provide symptomatic relief
D2 dopamine antagonist 3rd line
4
Q
Mechanism of 3 common drugs
A
Antacid - buffer HCl to reduce symptoms of excess acid
PPI - Inactivate H/K ATP pump to reduce gastric acid secretion
H2 antagonist - block H2 so histamine cant bind and activate downstream acid produce
5
Q
How do NSAIDS work
A
Inhibit COX-1 enzyme disrupting prostoglandin production so stimulating histamine and gastric acid
