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GI Micro Flashcards

(56 cards)

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1
Q

ANUG

A

Fusospirochetal Complex

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2
Q
A

ANUG

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3
Q

Aggressive periodontitis

A

Aggregatibacter Actinomycetemcomitans

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4
Q
A

Aggregatibacter Actinomycetemcomitans

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5
Q

Noma

A

Aggressive ANUG

Cancrum Oris

Gangrenous Stomatitis

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6
Q

Cervicofacial Actinomycosis

A

Actinomyces Israelii

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7
Q

Lumpy Jaw

A

Actinomyces Israelii

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8
Q
A

Actinomyces Israelii

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9
Q

Thrush

A

Candida

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10
Q
A

Candida

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11
Q
A

Porphyromonas Gingivalis

Prevotella Intermedia

Tannerella Forsythia

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12
Q

Chronic Periodontitis

A

Porphyromonas Gingivalis

Prevotella Intermedia

Tannerella Forsythia

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13
Q

Normal flora - possibly proctective

A

Veillonella Spp

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14
Q
A

Veillonella Spp

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15
Q
A

Primary colonizer of dental plaques

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16
Q

Actinomyces Viscosus

A

Primary colonizer of dental plaques

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17
Q

Shigella Disease

A

Dysentery

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18
Q

Shigella Characteristics

A

Gram negative

Rod

Non-sporulating

Facultative Anaerobe

Non-motile

Non-lactose fermenting

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19
Q

Dysentery

A

Watery to bloody diarrhea

Fever

Cramps

Tenesmus

Multiple shallow ulcers on scope - looks like IBD

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20
Q

Shigella Toxins

A

Pic -Mucus cleaving enterotoxin

Sig A - Cytotoxin

Sep A - Unknown

LPS - O antigen

Actin binding protein (uses cells own transporters)

Shigatoxin

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21
Q

Shiga toxin

A

60S ribosome inactivator

Endothelial dammage

Induce inflammatry cytokines

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22
Q

Shigella Complications

A

HUS - especially after ABx

Autoimmune disease

Reiter’s syndrome/reactive arthritis (HLA-B27)

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23
Q

Vibrio

24
Q

Cholera

Study These Flashcards
A

Profuse watery diarrhea

Cramps

Nausea/Vomitting

25
Vibrio characteristics
Gram - comma shaped rod Motile Flagellated Grows yellow on TCBS agar
26
Vibrio Toxins
Cholera Toxin A and B - perm upregulate Adenylate cylcase Heat labile enterotoxin Ctx A is similar to LT in E. Coli
27
Clostridium Characteristics
Gram postivie rod Spore forming Obligate anaerobe Catalase negative Oxidase negative Motile
28
C diff
Psuedomambranous colitis Post antibiotics Diarrhea - watery or bloody Cramps, fever Leukocytosis
29
Clostridium Toxins
Toxin A - Enterotoxin increases secretion Toxin B- Cytotoxin disrupts cytoskeleton
30
Clostridium Perfringens Differences
Enterotoxin (like cdiff toxin A) Without fever Alpha toxin - Degrades cell mbe Myonecrosis - Muscle breakdown (gas gangrene) Double zone of hemolysis on blood agar
31
Enterobacteriacea Characteristics
Gram negative rods Catalse positive Oxidase negative Facultative anaerobe Ferment glucose Ferment lactose (E. coli)
32
E. Coli
Travelers Diarrhea Related to shigella
33
SS Agar
Salmonella black centers E. Coli Pink Shigella Teal
34
ETEC - Enterotoxigenic E. Coli
LT and ST cytotoxins Travelers diarrhea Foodborne or contaminated water supply
35
AEEC- Attaching and effacing E. Coli
Destroy surface - form actin pedestals Microvilli are effaced from surface Enterocyte exfoliation EPEC - Peds STEC = Shigella like
36
EHEC - Enterohemorrhagic STEC
SHiga toxin producing Zoonotic Can cause HUS like shiga
37
EAEC- Enteroaggregative E. Coli
Common in US Acute or chronic Dangerous in HIV
38
EIEC- Enteroinvasive E. Coli
Dysentery like symptoms - bloody stool Similar presentation to shigella (more so than EHEC???)
39
Heat stabile proteins
Released upon lysis STa/b - Hypersecretion and malaboption EAST1 - Enhances effect of other toxins
40
Campylobacter Characteristics
Gull-winged shaped (spiral) Gram negative Microaerophilic (strict) Grows in high heat Oxidase positive Catalase variable Grows on Skirrow agar
41
Campylobacter enteritis
Severe Abd pain Fever Watery to dysentery (sometimes) Reactive arthritis Guillan-Barre
42
Campylobacter toxicity
Major outer mbe protein (adhesion) Cholera-like toxin = enterotoxin (increases cAMP) Cytolethal distending toxin (DNAse) - distends host cells S. Layer (sweater layer)
43
Yersinia Enterocolitica
Emerging diarrheal pathogen Enteric like illness May mimic appendicitis
44
Enterococcus
VRE (e. faecalis, e. faecium)
45
Salmonella
Fever, cramps, diarrhea, vomiting 2-3 duration Shed for weeks
46
Salmonella characteristics
Gram negative rod Non-spore forming Facultative Anaerobe Motile Does not ferment lactose
47
S. enterica typhi, typhimurium, enteritidis
Typhoid fever Septic Enterocolitis
48
SS Agar - Salmonella
Black growth - especially in center of colony
49
Clostridium botulinum
Toxin A, B, E, and F Intoxication Cleaves SNARE proteins which prevents exocytosis of neurotransmitters
50
Clostridium Boltulinum Characteristics
Gram positive bacilli Obligate anaerobe Endospore in soils and H20
51
Botulism vectors
Bulging cans and honey
52
Bacillus Cerus
Espec. Rice linked to vomitting illness Veggies/meat linked to diarrheal
53
B. Cerus Characteristics
Gram positive sporultation Motile No Capsule
54
Listeria Monocytogenes
Bacteria highly resistant to food safety Food sickness Granulomatosis infantiseptica Meningitis
55
Listeria Characteristics
Gram positive Non-sporulating Catalase positive Motile - actin binding Growth in wide range of environments End-over-end motility at room temp
56
Granulomatosis infantiseptica
In utero infection Neonatal sepsis Pustular lesions Granulomas with listeria inside

GI Self (2 decks)

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