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Year 2 Med > GI pharmacology > Flashcards

GI pharmacology Flashcards

1
Q

Acid Suppression drugs

A

Antacids, H2 receptor antagonists, PPI

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2
Q

Drugs affecting motility

A

Anti-emetics, anti-muscarinics, anti-soasmodics, anti-motility

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3
Q

Drugs for IBD

A

Aminosalicylates; corticosteroids; immunosupperants; biologics

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4
Q

Drugs affecting biliary secretions

A

bile acid sequestrants, ursodeoxycholic acid

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5
Q

What is the difference between antacid and alginate

A

Antacid: neutralises acid for indigestion relief
Alginates: creates a protective reflux barrier

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6
Q

Function and types of PPI

A

Irreversible inhibitor of H/K atpase
targets parietal cells
Omeprazole, oral or IV

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7
Q

Adverse effects of PPI

A

C.diff
B12 deficiency
ECL tumours

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8
Q

Types of drugs for intestinal motility

A

Purgatives: increase motility
Anti-diarrhoeal: reduce motility
Anti-spasmodics: decrease smooth muscle tone.

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9
Q

Drugs causing Acute hepatitis

A

Paracetamol, isoniazid, ritonavir, troglitazone

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10
Q

Drugs causing Chronic hepatitis

A

Diclofenac, methyldopa, minocycline, nitrofurantoin

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11
Q

Drugs causing Acute Cholestasis

A

ACE inhibitors, co-amoxiclav, chlorpromazine, erythromycins

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12
Q

Drugs causing mixed hepatitis

A

Phenytoin, sulfoamides

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13
Q

drugs causing Non-alcoholic steatohepatitis

A

Amiodarone, tamoxifen

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14
Q

drugs causing fibrosis/cirrhosis

A

Methotrexate

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15
Q

What is the Child-Pugh classification

A

allows assement of hepatic impairment

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Year 2 Med (8 decks)

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