GI Toxins and Treatments Flashcards

1
Q

PART A
Poison/Medication - Treatment

A
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2
Q

Tricyclic Antidepressants (Amitriptyline, Notriptyline, Clomipramine, Imipamine, Doxepin)

A

Sodium bicarbonate
-for prolonged QT interval (cardiotoxicity)

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3
Q

Amphetamines (methylphenidate, street amphetamines, etc.)

A

Ammonium chloride

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4
Q

Opioids (heroin, fentanyl, codeine, morphine, oxycodone, hydrocodone)

A

Naloxone, Naltrexone

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5
Q

Benzodiazepines (-azepam)

A

Flumenazil if severe

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6
Q

Beta Blockers

A

Glucagon

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7
Q

Theophylline (inhaler)

A

Beta Blockers

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8
Q

Digitalis

A

Digibind

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9
Q

Methemoglobin (from Dapsone, for example)

A

Methylene Blue, Vitamin C

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10
Q

Wafarin

A

Vitamin K and fresh frozen plasma

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11
Q

Heparin

A

Protamine sulfate

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12
Q

Ethylene glycol (Antifreeze)

A

IV ethanol infusion

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13
Q

PART B
Toxin - Overdose Sx - Treatment

A
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14
Q

Acetaminophen (Tylenol)

A

-Symptoms: hepatic necrosis, RUQ pain, jaundice, coagulation abnormalities

-Treatment: N-acetylcysteine or activated charcoal

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15
Q

Salicylates (aspirin, Pepto Bismol, Ben Gay)

A

-Symptoms: Respiratory alkalosis, fever, seizures, coma, renal failure, pulmonary edema

-Treatment: ABC’s, glucose for CNS symptoms, IVF

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16
Q

Bases (oven cleaner, drain cleaner, bleach)

A

-Symptoms: Esophageal or gastric perforation, respiratory distress, irritated mucous membranes

-Treatment: Supportive, emesis prevention, milk, NO GASTRIC LAVAGE

17
Q

Anticholinergics (Antihistamines, Atropine, TCA’s)

A

-Symptoms: hyperthermia (no sweating), tachycardia, hypertension, hot/flushed/dry skin, mydriasis

-Treatment: Physostigmine (acetylcholinesterase inhibitor), Sodium bicarbonate for TCA toxicity

18
Q

Cholinergics (organophosphates, insecticides, pesticides)

A

-Symptoms: salivation, lacrimation, urination, diarrhea, emesis, miosis

-Treatment: Atropine + Pralidoxime

19
Q

Iron

A

-Symptoms: GI symptoms

-Treatment: Emesis with gastric lavage, whole bowel irrigation, Deferoxamine