GIT Flashcards
(41 cards)
- The following statements regarding acute pancreatitis are correct:
(a) Mumps is a recognised cause.
(b) Pancreatic necrosis demonstrated on CT is associated with a mortality of 5-10%.
(c) Pancreatic oedema is a late sign.
(d) Haemorrhagic pancreatitis is diagnosed by the presence of hypodense areas of 5-20 Hounsfield units on CT.
(e) Right-sided pleural effusion is seen in 5%.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Alcohol and gallstones on the commonest cause of acute pancreatitis.
Left-sided pleural effusion is seen commonly.
Pancreatic oedema is the earliest sign of acute pancreatitis.
Haemorrhagic pancreatitis is diagnosed by the presence of hyperdense areas.
- Regarding hepatocellular carcinoma:
(a) Haemochromatosis is a recognised cause.
(b) It is the commonest primary visceral malignancy in the world.
(c) Elevated alpha-fetoprotein is found in 50-60% of cases.
(d) Has a higher incidence in macronodular than micronodular cirrhosis.
(e) On MR, hepatoma has a well defined, hypointense capsule on T1 weighted images.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Causes of hepato-cellular carcinoma are haemochromatosis, cirrhosis, hepatitis, Wilson’s disease, alpha 1 antitrypsin
deficiency .
Elevated alpha feto-protein levels are found in 50-60% cases of hepato-cellular carcinoma.
On MRI, hepatoma shows increased signal intensity on T2-weighted images with peripheral gadolinium enhancement
in 20% of the cases.
- Regarding pancreatic islet cell tumours:
(a) Insulinoma is found predominantly in the pancreatic body and tail.
(b) Glucagonoma is the commonest functioning islet cell tumour.
(c) Glucagonoma is a hypervascular tumour.
(d) Glucagonoma undergoes malignant transformation in 5-10%.
(e) Multiple insulinomas are associated with MEN Type 1.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Insulinoma does not have any predilection for any part of the pancreas. The undergo malignant transformation in 5-
10% of the cases.
Glucagonoma is the second commonest functioning islet cell tumour. The hypervascular and undergoes malignant
transformation in 80% of the cases.
- The following statements regarding splenic lymphoma are correct:
(a) The spleen is involved at presentation in 30-40% of patients with non-Hodgkin’s lymphoma.
(b) When there is lymphomatous involvement of the spleen, splenomegaly is seen in 70-80%.
(c) Focal splenic deposits are usually well defined, round lesions of increased brightness on ultrasound.
(d) Splenic lymphoma deposits commonly calcify.
(e) Lymph nodes are seen in the splenic hilum in 50% of patients with Hodgkin’s lymphoma.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Splenic lymphoma shows focal deposits which are usually well defined and hypoechoic on ultrasound.
When there is lymphomatous involvement of the spleen, splenomegaly is seen in the percent of the cases. In patients
with Hodgkin’s lymphoma, lymph nodes are seen in the splenic hilum in 10-20% of the patients.
- Regarding Budd-Chiari syndrome:
(a) It can be caused by obstruction of the suprahepatic IVC.
(b) On early CT images, the central liver enhances prominently and the peripheral liver weakly.
(c) The caudate lobe is markedly atrophic.
(d) A ‘spider’s web’ appearance at hepatic venography characteristic.
(e) On MRI images ‘comma-shaped’ intrahepatic collateral vessels are seen.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Caudate lobe is enlarged and hypertrophied in Budd chiari syndrome .
Flip-flop enhancement pattern is seen with central hepatic enhancement in the early phase and peripheral enhancement
in the late phase.
Thrombosis in hepatic veins is more common cause than obstruction of the suprahepatic IVC.
- The following statements concerning oesophageal carcinoma are correct:
(a) 90% of cases are squamous cell carcinomas.
(b) Most commonly located in the upper third of the oesophagous.
(c) Plummer-Vinson syndrome is a recognised predisposing factor.
(d) It is associated with ulcerative colitis.
(e) Commonest appearance on double contrast barium swallow is of a large ulcer within a bulging mass.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Oesophageal carcinoma most commonly located in the middle and lower third of the oesophagus. Only 20% occur in
the upper one third .
Polypoidal or fungating form is the commonest type.
Predisposing factors for oesophageal carcinoma include Barrett’s esophagus, alcohol abuse, smoking, coeliac disease
& Achalasia.
- The following statements regarding Meckel’s diverticulum are correct:
(a) Is present is 2-3% of the population.
(b) Identification of Vitelline artery is pathognomonic.
(c) Located in the mesenteric border of the ileum.
(d) In children, small bowel enema is the best investigation to identify it.
(e) Can present as intussusception in children
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Meckel’s diverticulum located at the antimesenteric border of the ileum.
Best investigation diagnosed Meckel’s diverticulum in children is a radionuclide technetium 99 pertechnetate scan.
- Features of pseudomembranous colitis include:
(a) An acute infective colitis due to Chostridium perfringens toxin.
(b) Most commonly affects the transverse colon.
(c) Bowel wall thickening is the commonest appearance on non-contrast CT images.
(d) ‘Thumbprinting’ is seen on the plain abdominal radiograph.
(e) Ascites is a recongnised feature.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Pseudomembranous colitis is caused by Clostridium difficile toxin.
It most commonly affects the rectum.
Ascites is a recognised feature in severe cases
- Regarding ischaemic colitis:
(a) Griffith point is the most commonly affected segment.
(b) The right colon is involved in 30% of cases.
(c) Usually occurs in the first decade of life.
(d) Barium enema is usually only abnormal in 50-60% of cases.
(e) Portal vein gas is of little clinical significance.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Ischaemic colitis is usually seen in patients >50 years of age .
Barium enema is abnormal in 90% of the cases showing features of bowel wall thickening, loss of haustrations and
thumbprinting.
Evidence of portal vein gas is seen in very rae cases and is a preterminal sign.
- Features more in keeping with jejunum than ileum include:
(a) Thinner walls.
(b) Thicker valvulae conniventes.
(c) More numerous Peyer’s patches.
(d) One or two arterial arcades with long branches.
(e) 2.5cm width diameter
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Ileum is 2.5 cm in diameter and jejunum is 3-3.5 cm.
Jejunum shows a few Peyer’s patches but they are larger.
Jejunum as thicker walls as compared to ileum.
- Regarding diverticular disease:
(a) Colonic diverticulosis affects 70-80% by 80 years of age.
(b) Rectosigmoid colon is most commonly affected.
(c) 10-25% of individuals with colonic diverticular disease develop diverticulitis.
(d) Fistula formation occurs in 40-50% of cases complicating acute diverticulitis.
(e) Moderate diverticulitis is present when the bowel wall is thickened >3mm.
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Fistula formation is seen in 15% of the cases of complicated acute diverticulitis.
- Regarding Peutz-Jeghers syndrome:
(a) It is inherited in an autosomal recessive manner.
(b) There is an association with intussusception.
(c) Patients are at increased risk of gastrointestinal adenocarcinoma.
(d) Polyps are seen in the stomach.
(e) It is associated with pigmented lesions on the fingers
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
It is an autosomal dominant disease showing polyps in stomach, small intestine especially jejunum and may be seen in
colon.
There is an increased risk of a adenocarcinoma but polyps themselves are hamartomatous and benign.
- Regarding Carcinoid tumour:
(a) Carcinoid syndrome is the presentation in only 20-30% of cases.
(b) It is rarely multiple.
(c) The commonest location for this tumour is the appendix.
(d) 50% of tumours greater than 2cm in size have metastases.
(e) Angulation of small bowel loops on small bowel follow through is a diagnostic feature.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Carcinoid tumour are multiple in 33% of the cases. Carcinoid syndrome is seen in only 7% of the cases and arises
due to excess serotonin levels.
The 50% of tumours of 1–2 centimetres in size have metastasis, 85% of tumour was greater than 2 cm have
metastasis.
- The following statements regarding Achalasia are correct:
(a) Dilatation of the oesophagus begins in the upper third.
(b) Multiple non-peristaltic contractions are seen on barium swallow.
(c) A prominent gastric air bubble is seen on erect CXR.
(d) There is an association with plummer-Vinson syndrome.
(e) Squamous cells carcinoma of the oesophagus is a recognised complication
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Achalasia is not associated with Plummer-Vinson syndrome.
Gastric air bubble is usually absent on erect chest x-ray.
Dilatation of the oesophagus begins in the upper one third and progresses to involve the entire length
- Following statements regarding lymphoma of the gastrointestinal tract are correct:
(a) There is an increased risk associated with ulcerative colitis.
(b) The stomach is the most common site of involvement by non-Hodgkin’s lymphoma.
(c) In the colon the rectum is most commonly involved.
(d) Diffuse involvement of the whole stomach is seen in 10-15%.
(e) Presents with thickened valvulae conniventes in the small bowel.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Lymphoma of the gastrointestinal tract has an increased risk association with Crohn’s disease, coeliac disease, AIDS
and SLE.
Diffuse involvement of the stomach is seen in 50% of the cases.
Caecum is most commonly involved in colon
- Regarding peritoneal spaces:
(a) The right subhepatic space communicates with the lesser sac.
(b) The left subphrenic space is separated from the right subphrenic space by the falciform ligament.
(c) The bare area of the liver is located between reflections of the right and left coronary ligaments.
(d) The splenorenal ligament separates the left subphrenic space from the left paracolic gutter.
(e) The gastrocolic ligament connects the lesser curve of the stomach to the superior aspect of the transverse colon.
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Phrenico-colic ligament separates the left subphrenic space from the left paracolic gutter since it attaches to the
descending colon to the left hemidiaphragm .
The gastrocolic ligament connects to the greater curvature of the stomach to the superior aspect of the transverse
colon.
- Regarding gastrointestinal stromal tumours (GIST):
(a) The most significant criteria for predicting malignant potential is tumour size.
(b) It is a cause of haematemesis.
(c) The commonest location is the sigmoid.
(d) There is an association with neurofibromatosis Type 1
(e) Contrast enhancement is invariably uniform.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Gastrointestinal stromal tumour does not cause hematemesis since they are mostly exophytic.
It is commonly located at stomach. There is heterogenous enhancement with significant haemorrhage and necrosis.
- Regarding hepatic adenoma:
(a) It is associated with Type 1 glycogen storage disease.
(b) Is located in the left lobe of the liver in 60-75% of cases.
(c) Is easily differentiated from hepatocellular carcinoma on MRI.
(d) Often reduces in size during pregnancy.
(e) Is hypovascular.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Hepatic adenoma increases in size during pregnancy.
There are hypervascular lesions with significant risk of bleeding at the biopsy and hence biopsy is contraindicated.
There are indistinguishable on all MRI sequences.
There mostly located in the right lobe of liver in 60-75% of the cases
- The following statements regarding primary sclerosing cholangitis are correct:
(a) The common bile duct is usually spared.
(b) It affects only the intrahepatic bile ducts.
(c) Echogenic portal triads are identified on ultrasound.
(d) There is a 10-15 times increased risk of developing cholangiocarcinoma.
(e) It is associated with positive antimitochondrial antibodies.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Primary biliary cirrhosis is associated with positive antimitochondrial antibodies.
Primary sclerosing cholangitis affects intra-and extrahepatic bile ducts.
Common bile duct is always involved.
- which of the following statements are correct about Insulinomas:
(a) The majority are benign.
(b) 90% are less than 2cm in diameter.
(c) Are frequently multiple.
(d) Are associated with MEN 1 syndrome.
(e) More than 50% can be localized using an octreotide scan.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Only 10% of insulinomas are multiple. When multiple, the individual lesions are smaller. Malignant lesions tend to be
larger than benign.
Patients with MEN 1 syndrome tend to have multiple small insulinomas
- Focal nodular hyperplasia (FNH):
(a) Multiple lesions are seen in 40-60% of cases.
(b) Is the most common benign liver tumour.
(c) Has a low signal on T2 weighted MRI post-iron oxide administration.
(d) Central scar is a pathognomonic feature.
(e) Central scar is hyperdense on arterial phase CT.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
FNH is the second most common benign liver tumour after haemangioma. The usually occurs in young patients with
more female ratio.
There are multiple in 20% of the cases.
A central scar is usually seen in FNH however it can be seen in giant haemangioma, hepato cellular carcinoma and
hepatic adenoma.
Central scar of FNH is non-enhancing on arterial phase however the rest of the tumour enhances significantly
- Which of the following are correct about Crohn’s disease:
(a) There is an increased risk of malignancy.
(b) Pseudo-diverticula are typically found on the antimesenteric side of the bowel.
(c) Mural stratification on CT indicates active disease.
(d) Colonic involvement is usually accompanied by small bowel disease.
(e) Apthous ulcers are an early finding.
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
The comb sign in crohn’s disease depicts the pericolic and perienteric fat stranding due to increased mesenteric
vasculature.
Disease can affect any part of the gastrointestinal tract from mouth to the anus however small intestine is most
frequently involved particularly the terminal ileum
- Which of the following are correct about Emphysematous cholecystitis:
(a) Gallstones are present in over 90% of cases.
(b) The most common causative organism is staphylococcus aureus.
(c) Is associated with diabetes in 5-10% of cases.
(d) Intramural gas is characteristic.
(e) Is usually successfully treated with antibiotics alone.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Emphysematous cholecystitis is most commonly caused by clostridia and E.Coli species.
It commonly affects order men and has association with diabetes mellitus in about 50% of the cases.
Gallstones are present less frequently. It can rapidly lead to the perforation and septic shock.
There is gas in the lumen of the gallbladder, in the wall or in the pericholecystic space in the absence of any fistula
with the intestine.
- Which of the following are correct about Caroli’s disease:
(a) Is inherited as an autosomal dominant disorder.
(b) Is associated with autosomal dominant polycystic kidney disease.
(c) 70-80% have extrahepatic bile duct dilatation.
(d) Is associated with ulcerative colitis.
(e) Cholangiocarcinoma develops in 5-10%
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Caroli’s disease is rare autosomal recessive disorder showing abnormal development of intrahepatic bile ducts.
The differential diagnosis includes primary sclerosing cholangitis. The ductal dilatation in primary sclerosing
cholangitis is a rarely saccular and is typically more isolated and fusiform. 70% of the patient’s with primary
sclerosing cholangitis have co-existing inflammatory bowel disease.
There are multiple intrahepatic cyst that communicate with the biliary tree with intrahepatic bile duct dilatation,
irregular bile duct walls, strictures and stones in Caroli’s