GIT

Question 1

What are prokinetic agents?

Answer 1

Prokinetic agents are drugs that increase gastrointestinal (GI) motility and transit of material in the GI tract.

Question 2

What are some examples of dopamine receptor antagonists?

Answer 2

Metoclopramide and domperidone.

Question 3

What are serotonin receptor agonists?

Answer 3

Serotonin receptor agonists (5HT4 agonists) include cisapride and prucalopride.

Question 4

What is motilin?

Answer 4

Motilin is a hormone that stimulates GI motility.

Question 5

What are macrolide antibiotics that mimic motilin?

Answer 5

Erythromycin.

Question 6

What are miscellaneous prokinetic agents?

Answer 6

Miscellaneous agents include Sincalide, Camicinal, Relamorelin, Velusetrag, and naronapride.

Question 7

What is Sincalide?

Answer 7

Sincalide is the C-terminal octapeptide of CCK.

Question 8

What is Camicinal?

Answer 8

Camicinal is a motilin receptor agonist.

Question 9

What is Relamorelin?

Answer 9

Relamorelin is a ghrelin receptor agonist.

Question 10

What are Velusetrag and naronapride?

Answer 10

Velusetrag and naronapride are 5HT4 agonists.