GIT 3 Flashcards
(35 cards)
Types of polyps
Hyperplastic.
Inflammatory.
Hamartomatous.
Lymphoid.
Adenomatous or adenomas.
“Neoplastic”
Most common type of polyps
Hyperplastic polyps
Small, nipple-like hemispheric polyps, common in rectosegmoid colon
Hyperplastic polyps
Has a serrated epithelial profile and an irregular crypt architecture
Hyperplastic polyps
Sporadic, large rounded polyps with stalks, common in children
Hamartomatous polyps
melanotic mucosal and cutaneous pigmentation around the lips, oral mucosa, face, genitalia, and palmar surfaces of the hands.
Peutz Jeghers polyps
Types of adenomas
Tubular.
Villous.
Tubulovillous.
Sessile Serrated.
The more common and dangerous type of adenomas
Tubular adenoma
Most tubular adenomas are
Small and pedunculated
Most villous adenomas are
Large and sessile
The malignant risk of the adenomatous polyps depend on
Size.
Histologic architecture.
Dysplasia.
FAP classified into
Classic.
Attenuated.
Gardner syndrome.
Turcot syndrome.
FAP + multiple osteomas + epidermal cysts
Gardner syndrome
FAP + tumors in the CNS (medulloblastomas)
Turcot syndrome
APC mutation
FAP
Mismatch repair gene defect (MMRd)
HNPCC (Lynch syndrome)
Mucus in the cytoplasm, pushing the nucleus aside is seen in
Signet ring carcinoma
Intestinal polyps are more common in
Older adult + rectosegmoid
Isolated hamartomatous polyps found in colon of adults
Retention polyps
Hamartomatous polyps common in
Rectum
Which type of polyps is seen in PJ syndrome
Hamartomatous
PJ syndrome patients are at risk of?
Intussusception
The stalk of tubular adenomas is composed of
Vascular fibromuscular tissue
The most worrisome lesion regarding adenomatous polyps
Sessile polyp > 4cm
