Glands of Digestion: Liver Flashcards Preview

Organ Histology Final: 7 and 8 > Glands of Digestion: Liver > Flashcards

Flashcards in Glands of Digestion: Liver Deck (25)
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1
Q

What is the largest gland in the body with exocrine AND endocrine functions?

A

Liver

2
Q

What are the general functions of the liver?

A

Metabolism of lipids, carbs, proteins
Production of blood proteins, factors, non-essential vitamins
Detoxifies blood
Produces hepatic (primary) bile
Stores certain vitamins (ie. vitamin A, B12)

3
Q

What is an exocrine function of the liver?

A

Produces hepatic (primary) bile

4
Q

Why are hexagonal shaped lobules difficult to distinguish in humans?

A

Due to lack of CT between lobules

5
Q

What cell types are contained in the liver?

A
Hepatocytes
Kupffer cells (stellate macrophages)
Ito cells (hepatic stellate cells)
Pit cells
Hepatic progenitor cells
6
Q

What is the composition of hepatocytes?

A

Microvilliated cuboidal cells with lateral bile canaliculi between adjacent hepatocytes

7
Q

What are the functions of the hepatocytes?

A

ALL the general functions of the liver

8
Q

What allows hepatocytes to collect bile?

A

Their bile canaliculi

9
Q

Bile moves from the hepatocytes towards ___ in the portal triad?

A

Bile duct bronchi

10
Q

How are hepatocytes arranged?

A

In rows between hepatic sinusoids like spokes of a wheel

11
Q

What are Kupffer cells/stellate macrophages?

A

Resident macrophages that develop from monocytes

12
Q

What is the function of Kupffer cells?

A

Phagocytosis of debris and aged RBC; they act like an APC

13
Q

What are the functions of Ito cells/hepatic stellate cells?

A

Store lipids for immediate use
Store vitamin A
Produce collagen I, III, IV and growth factors

14
Q

What are pit cells?

A

NK cells

15
Q

What cell type is responsible for regenerative capabilities?

A

Hepatic progenitor cells

16
Q

What are the branches of the Portal triads?

A

Hepatic artery
Portal vein
Bile duct
Lymph vessels

17
Q

What are hepatic sinusoids?

A

Dilated, fenestrated thin walled vessels found between rows of hepatocytes

18
Q

What do hepatic sinusoids carry?

A

A mixture of venous (75%) and arterial blood (25%)

19
Q

What is the central vein?

A

Fenestrated thin walled vessel that collects blood from the hepatic sinusoids

20
Q

Blood flows from the Portal triad towards the___?

A

Central vein

21
Q

What other name refers to the space of Disse?

A

Perisinusoidal space

22
Q

Where is the space of Disse located?

A

Between hepatocytes and fenestrated hepatic sinusoids where blood can directly contact microvilliated surfaces of hepatocytes

23
Q

Why can the liver take over spleen function in about 24-48 hours?

A

Flow slows enough in the space of Disse so that cells can interact with the blood and its contents

24
Q

What is Glisson’s capsule made up of?

A

Dense irregular CT covered with serosa

25
Q

Is dense irregular CT the primary kind of CT present in the liver?

A

Yes, other CT is limited in the human liver