Glaucoma Meds 2 Flashcards by Kyou Tabemono

Q

Name 2 alpha 2 agonists

A

Apraclonidine 0.5% (iopdine)

Brimonidine 0.2% (alphagan)

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Q

Name 2 CAIz

A

Dorzolamide 2% (Trusopt)

Brinzolamide 1% (Azopt)

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Q

Ocular Side effect of cholinergic agonist

A

Brow ache

Accommodative spasm

Pupil block in advanced cataract

RD in high myopes

Sting

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Q

Systemic side effect of cholinergic agonist

A

Headache

Arrythymia

Salivation

Sweating

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Q

Ocular contraindications for cholinergic agonist

A

High myope

Cataract

Px <40 as can’t tolerate spasm

Inflammation

Uveitic/neovascular glaucoma

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Q

Systemic contraindication for cholinergic agonist

A

Asthmatics

Ulcers

Bladder dysfunction

Parkinson

Already uses systemic cholinergic agonist

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Q

Ocular side effect of cholinesterase inhibitors

A

Iris cysts

Acceleration of cataract

RD

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Q

Ocular side effect of a2 agonist

A

Conjunctival blanching

Minimal mydriasis

Lid retraction and dry eye

Itch

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Q

Systemic side effect of a2 agonist

A

Dry mouth

Fatigue

Taste abnormality

Headache

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Q

Contraindication for a2 agonist

A

CVD

Maoi

TCA

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Q

Ocular side effect of beta blockers

A

Dry eye

Allergy

Decreased corneal sensitivity

Punctuate epithelial erosion

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Q

Systemic side effect of beta blockers

A

Impotence

Depression

Bradycardia

Bronchospasm

Hypotension

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Q

Contraindication for beta blocker

A

Narrow angles

Impotence

Depression

Nightmares

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Q

Ocular side effect of CAI

A

Sting

Irreversible corneal decompensation

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Q

Systemic side effect of CAI

A

Bitter taste

Headache

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Q

Contraindication for CAI

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A

Corneal endothelial compromise

Hypersensitivity to sulphonamides

Q

Side effect of CAi (acetazolamide version)

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A

Anorexia

Parses thesis of hands/feet

Aplastic anaemia and Steven Johnson

Renal stones

Q

Contraindication of CAI

Acetazolamide version

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A

Hypersensitivity to sulphonamides

Renal problems

Pregnancy

Q

Side effect of prostaglandin analogues

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A

Periorbiral pigment

Increase lash thickness and length

Deactivation of AU and herpes

CMO

Q

Contraindication for Prostagalndin analogues

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A

Inflammmatory disease

CMO

HSV KERATITIS

Pregnancy

Q

Why is mono therapy preferred

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A

Convenient

Less likely for mistakes

Less drug interactions

Less preservative so less toxicity to cornea

Q

How do prostaglandin analogues work

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A

Bind to prostanoid FP receptor in CB

Increase MMP

relax ciliary muscle and remodel ECM of ciliary muscle

Increase uveoscleral outflow

Q

Systemic side effect of prostaglandin analogues

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A

Headache

Respiratory problems

Q

Name non selective beta blockers

Study These Flashcards

A

Timolol 0.25/0.5 (timoptic)

Carteolol 1%

Metipranolol 0.3 (optipranolol)

Levobunolol 0.25 (Betagan)

Name the B1 selective Beta blocker

Betaxolol 0.25/0.5 (Betoptic)

Why is betaxolol good and bad

Selective for B1 so less risk to asthmatics but less IOP decrease than timolol