GlP-1 RA

Question 1

GLP-1RA

Answer 1

Glucagon Like Peptide Receptor Agonist

Analog of GLP an incretin hormone. Second line therapy after Metformin.

Question 2

Tanzeum

Answer 2

Albiglutide (GLP1RA) SubQ 30mg Qweekly. Up to 50mg Qweekly

Question 3

Trulicity

Answer 3

Dulaglutide (GLP1RA) SubQ 0.75mg Qweek. Up to 1.5mg Qweek. Miss dose may take within 3 days then resume usually day of dose.

Question 4

Bydureon

Answer 4

Exenatide (GLP1RA) SubQ 5mcg BID within 60 min prior to meals. After 1 month my increase up to 10mcg. Extended release formulation is 2mg Qweekly.

Question 5

Victoza for diabetes Saxenda for weight loss.

Answer 5

liraglutide (GLP1RA) Victoza is subQ 0.6mg qd for 7days. Then increase to 1.2mg QD then can go to 1.8mg QD if needed.
Saxenda is 0.6mg qd for 7 days up to 3mg.

Question 6

Incretin Hormone

Answer 6

GLP it increases insulin production. Decreases Glucagon production (this decreases glucose synthesis from liver) also slows gastric emptying making one feel full. therefore decreasing food intake.