Glycolysis Flashcards

1
Q

What is the first stage of glycolysis? Glucose to the product and enzyme/resource used.

A

Glucose 6-Phosphate, enzyme used is Hexokinase, 1 ATP used and turns into ADP

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2
Q

What is the second stage of glycolysis? Glucose 6-phosphate to the product and enzyme/resource used.

A

Fructose 6-Phosphate, Phosphoglucose isomerase.

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3
Q

What is the third stage of glycolysis? Fructose 6-phosphate to the product and enzyme/resource used.

A

Fructose 1,6-bisphosphate, phosphofructokinase, 1 ATP to ADP

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4
Q

What is the fourth stage of glycolysis? Fructose 1,6-bisphosphate to the product and enzyme/resource used.

A

Glyceraldehyde 3-phosphate, uses aldolase, dihydroxyacetone phosphate is also made.

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5
Q

What happens to dihydroxyacetone phosphate? What enzyme does this? What problem is linked to this enzyme?

A

It is converted into Glyceraldehyde 3-phosphate by triose phosphate isomerase (TPI). TPI deficiency is the only glycolytic enzymopathy that is fatal.

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6
Q

What is the fifth stage of glycolysis? Glyceraldehyde 3-phosphate to the product and enzyme/resource used.

A

1,3-bisphosphoglycerate, uses glyceraldehyde 3-phosphate dehydrogenase, Pi and NAD+ converted to NADH

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7
Q

What is the sixth stage of glycolysis? 1,3-bisphosphoglycerate to the product and enzyme/resource used.

A

3-phosphoglycerate, uses phosphoglycerate kinase, ADP to ATP

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8
Q

What is the seventh stage of glycolysis? 3-phosphoglycerate to the product and enzyme/resource used.

A

2-phosphoglycerate, uses phosphoglcyerate mutase

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9
Q

What is the eight stage of glycolysis? 2-phosphoglycerate to the product and enzyme/resource used.

A

phosphoenolpyruvate, uses enolase, makes H2O

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10
Q

What is the ninth stage of glycolysis? Phosphoenolpyruvate to the product and enzyme/resource used.

A

2x Pyruvate, uses pyruvate kinase, ADP to ATP

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11
Q

What is the overall gain of resources and why?

A

2 ATP and 2 NADH, as stage 2 occurs twice as there are 2 glyceraldehyde 3-phosphate molecules

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