Glycopeptides

Question 1

Name the Glycopeptide’s

Answer 1

Vancomycin
Teicoplanin

Question 2

Glycopeptide’s MOA

Answer 2

Interferes with cell wall synthesis by decreasing peptidoglycan synthesis

Question 3

Are Glycopeptide’s bactericidal or bacteriostatic

Answer 3

Bactericidal

Question 4

Glycopeptide’s Adverse Effects (common)

Answer 4

Phlebitis (more common with vancomycin)
(Inflammation of a vein near the surface of the skin)

Question 5

Glycopeptide’s Adverse Effects (infrequent)

Answer 5

Neurotoxicity (more common with vancomycin)
(more common when used with aminoglycosides or in renal impairment)

Question 6

Glycopeptides Adverse Effects (rare)

Answer 6

Ototoxicity (more common when used with aminoglycosides or in renal impairment)
Thrombocytopenia (low platelets)
Neutropenia (low WBC)