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Antibiotics > Trimethoprim and Sulfamethoxazole > Flashcards

Trimethoprim and Sulfamethoxazole Flashcards

1
Q

Trimethoprim and Sulfamethoxazole MOA

A

Inhibit bacterial folate production essential for bacterial growth

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2
Q

Is Trimethoprim and Sulfamethoxazole bactericidal or bactiostatic?

A

Bacteriostatic

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3
Q

Trimethoprim and Sulfamethoxazole Adverse Effects (common)

A

Hyperkalaemia
Nausea
Vomiting
Diarrhoea

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4
Q

Trimethoprim and Sulfamethoxazole Adverse Effects (infrequent)

A

Headache
Drowsiness
Photosensitivity

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5
Q

Trimethoprim and Sulfamethoxazole Adverse Effects (rare)

A

Electrolyte disturbances
C. diff

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6
Q

Trimethoprim and Sulfamethoxazole Counselling

A

Take with food to reduce stomach upset

Avoid excessive sun exposure

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7
Q

Trimethoprim and Sulfamethoxazole Interactions

A

Phenytoin
Methotrexate
Warfarin

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Antibiotics (12 decks)

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