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Business of science > group 11-15 > Flashcards

group 11-15 Flashcards

1
Q

what is immunogen

A

clinical stage company acquired by abbvie

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2
Q

what is the platform of immunogen

A

antibody drug conjugates used in cancer treatment

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3
Q

technology and ip of immunogen

A

targets cancer cells and cancer cells only via the use of cancer-killing toxins conjugated
to cancer cell antibodies

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4
Q

what is fusion pharmaceutical

A

clinical stage oncology company focused on developing next gen radiopharmaceuticals as precision medecine

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5
Q

what is the platform of fusion pharmaceutical

A

Targeted Alpha Therapies with Fast-ClearTM Linker technology to connect alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumours

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6
Q

what is macrogenetics

A

clinical stage biopharmaceutical company

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7
Q

platform of macrogenerics

A

latform includes multiple antibody technologies – primarily for the treatment of cancer.
o mAbs, ADCs, multi-specific Abs (DART® and TRIDENT®) which includes Next-Gen T-Cell engagers

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8
Q

what is avidity bioscience

A

clinical stage biopharmaceutical company focused on utilizing their tech to develop rna therapeutics

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9
Q

what is the platform of avidity bioscience

A

Proprietary Antibody Oligonucleotide Conjugates (AOC ), which combines the specificity of monoclonal
antibodies and the precision of oligonucleotides, to unlock the treatment for rare muscle diseases and for other rare
and common diseases.

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10
Q

what is ascendis pharma

A

clinical stage biopharmaceutical company that combines technological and therapeutics based approach

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11
Q

what is the platform of ascendis pharma

A

transcon (transient conjugation) technology

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12
Q

what is the platform of lyell immunopharma

A

-advanced cellular engineering with proprietary genetic and epigenetic reprogramming technologies
-targeting solid tumors with innovative therapies like lyl979

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13
Q

what is lyell immunopharma

A

pioneers in t cell programming for the treatment of solid tumors

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13
Q

what is biomarin pharmaceutical

A

glonal biotech company focused on using genetics and molecular biology to develop for rare disease

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13
Q

what is the tech platform for biomarin pharmaceuticals

A

-enzyme replacement therapy: providing synthetic copies of missing proteins to people with genetic conditions
-using adeno associated virus gene therapy for dna to cells

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14
Q

what is legend biotech

A

pioneed and leader in cell therapy
-has global collaboration in china, us, japan and europe

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15
Q

what is the platform for legend biotech

A

car-t cell therapies to improve cancers such as multiple myeloma

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16
Q

what is precigen inc

A

discovery and clinical stage biopharmaceutical company

17
Q

what is the platform for precigen inc

A

-ultracar-t cells
-focused on the development of gene and cell therapies for immuno-oncology, autoimmune and infectious diseases
-done through precision immunology with a framework of multifunctional therapies designed to work in combination

18
Q

what is prothena

A

late stage clinical biotech

19
Q

what is the platform for prothena

A

antibodies that target misfolded proteins, small molecules and vaccines

20
Q

what is alector

A

clinical stage biopharmaceutical, pioneering immuno-neurology, using insights into human genetics, immunology and neuroscience

21
Q

what is the platform of alector

A

monoclonal antibodies

22
Q

what is intellia

A

clinical stage biopharmaceutical company

23
Q

what is the platform for intella

A

crispr based genome editing technologies for human therapeutic use

24
Q

what is anavex

A

clinical stage biopharmaceutical company

25
Q

what is the platform of anavex

A

small molecule therapeutics that modulate sigma receptor 1 (sigmar1)

26
Q

whay is alnylam

A

biopharmaceutical company

27
Q

what is the platform of alnylam

A

Focused on discovering, developing, and commercializing RNAi therapeutics in genetic medicines, cardio-metabolic diseases, infectious diseases, central nervous system, and ocular diseases.

28
Q

what is ionis

A

Clinical stage pharmaceutical company specializing in discovery and development of RNA targeted medicines and gene editing to
treat neurological and cardiometabolic diseases

29
Q

what is platform of ionis

A

Antisense therapies to target specific mRNAs for degradation to decrease levels of disease-causing protein. In some
cases, antisense therapies may also be used to increase production of deficient mRNAs.

30
Q

what is arrowhead pharmaceuticals

A

clinical stahe biopharma company focusing on rnai tech

31
Q

what is the plastform of arrowhead pharma

A

rnai molecule trim platform leberages the body’s natural pathway to silence disease causing genes by triggering risc

32
Q

what is arbutus biopharma

A

clinical stage biopharmaceutical focused on chronic hep B treatment

33
Q

what is the platform of arbutus biopharma

A

combination therapy with rna interference (rnai) therapeutic and oral pd-L1 inhibitor to suppress HBV dna, reduce viral antigens and bost host immune response

34
Q

what is janux therapeutics

A

clinical stage biotech focused on the development of improved T cell engagers for the treatment of solid tumor cancers

35
Q

what is the platform of janux therapeutics

A

Tumor-Activated T Cell Engager (TRACTr) and Immunomodulator (TRACIr) platforms
* Enhanced specificity, stability, and sensitivity promises reduced limitations of canonical TCEs: CRS, off-target
toxicities, poor PK

36
Q

what is xencor

A

clinical stage biopharmaceutical company focused on engineering antibodies and citokines for the treatment of patients with cancer and autoimmune diseases

37
Q

what is the platform of xencor

A

-XmAb protein engineering platform
* XmAb Fc Domains augment native immune functions and/or control structure to preserve halflife, stability, and production of antibody treatments

38
Q

what is merus NV

A

clinical stage pharmaceutical company

39
Q

what is the platform of merus NV

A

-Multiclonics® Technology
o Technology: Developed novel, full length human IgG antibodies capable of binding multiple targets while
maintaining the long half-life and low immunogenicity of conventional monoclonal antibodies
o Created Biclonics® and Triclonics® technologies, through which these antibodies bind 2 or 3 targets,
respectively

40
Q

what is immunocore

A

leading biotech company focused on T cell receptor tech to develop therapies for cancer, infectuous diseases and autoimmune disorders

41
Q

what is the platform of immunocore

A

-Their novel ImmTAX molecules enhance immune recognition to eliminate infected or cancerous cells.
*KIMMTRAK, the first approved TCR therapy for metastatic uveal melanoma, targets the gp100 antigen.

42
Q
A

Business of science (21 decks)

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