Growth And Ax In Children-adolescents Flashcards

1
Q

2 types of growth restriction

A

Failure to thrive: underlying nutrition or chronic disease

Short stature - endocrine

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2
Q

When document height and weight in kids?

A

EVERYTIME!!

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3
Q

Why glucocorticoids bad for growth?

A

Inhibit chondroblastic maturation

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4
Q

How to get expected height?

A

Height of parents and subtract 6.5 girls and add 6.5cm for boys

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5
Q

Growth hormone mechanism

A

GH>GH receptor>IGF-1>Bone>growth

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6
Q

New born screening

A

Cystic fibrosis

PKU

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7
Q

Overweight is?

A

85%-95%

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8
Q

Failure to thrive is?

A
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9
Q

Obese is what centile?

A

> 95th %

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10
Q

What is the major contributor to growth spurt in puberty?

A

Estrogen.

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11
Q

Determinants of skeletal bone age delayed?

A

Hypothyroidism, glucocorticoid excess, growth hormone deficiency, chronic disease

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12
Q

What causes bone age acceleration

A

Obesity,
early puberty
Hyperthyroidism
Androgen excess

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13
Q

Nutritional causes of growth failure? 3

A

Undernutrition
Micronutrient deficiencies - iron, Vit D
Gut malabsorption - Coeliac, CF, Crohn’s

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14
Q

When does growth hormone secrete during 24 hour period?

A

At night

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15
Q

Endocrine causes of short stature?

A
Hypothyroidism (autoimmune)
GH deficiency
Glucocorticoid excess (GP: if asthma every 4-6 weeks)
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16
Q

What do kids with endocrine causes of short stature kids look like BMI wise?

A

Normal or overweight BMI

17
Q

Why cushing’s get muscle mass loss?

A

Get proteinolysis of muscles

Flat-lining of linear growth

18
Q

Growth with obesity is?

A

Accelerated