Growth Hormone Flashcards
(6 cards)
1
Q
Why does GH increase amino acid uptake (not breakdown)?
A
To prioritize protein synthesis for growth. Uses FFAs for energy instead.
2
Q
What stimulates GH secretion?
A
GHRH, ghrelin, sleep, exercise, fasting.
3
Q
What inhibits GH?
A
Somatostatin, IGF-1 (negative feedback).
4
Q
GH’s direct metabolic effects
A
↑ Lipolysis, ↑ gluconeogenesis, ↑ protein synthesis.
5
Q
GH’s indirect growth effects
A
Via IGF-1 → ↑ bone/cartilage/muscle growth.
6
Q
Acromegaly vs. Gigantism
A
Acromegaly: Adults (thick bones). Gigantism: Kids (↑ height).
