Guest Lecture

Question 1

Exudates

Answer 1

protein-rich fluid which which oozes into tissue or onto surfaces - made up of neutrophils and is made up of pus

Question 2

Transudate

Answer 2

protein-poor fluid permeating tissues in response to hemodynamic factors —> can occur in normal tissues as a response to heart and kidney disease

Question 3

Anaphylotoxins

Answer 3

C3a and C5a

Question 4

chemotactic factors

Answer 4

c5a and c3a

Question 5

opsonin

Answer 5

c3b

Question 6

acute inflammation

Answer 6

immediate reaction at sites of injury and infection; occurs as a rapid response (within minutes to hours) and has no secificity

1. blood vessel permeability changes
2. coagulation system and inflam mediators
3. opsonization (phagocytosis)

Question 7

what are the three opsonins mentioned?

Answer 7

1. immunoglobulins
2. complement byproducts like c3b
3. C-reactive protein (CRP)

Question 8

chronic infection

Answer 8

occurs when stimulus is persistent and doesnt go away, present in autoimmune diseases and viral infections

Question 9

how is chronic infection different than acute?

Answer 9

1. takes longer to develop
2. more likely to involve specific recognition through immune response
3. cell infiltrate is mainly lymphocytes and mononuclear phagocytes
4. theres a permanent change in tissue architecture like growth of new vessels, deformity or fibrosis

Question 10

Granuloma/granulomatous inflammation

Answer 10

masses of immune cells that form at sites of infection or inflammation