GUM Flashcards

1
Q

Name common causes of dysuria

A

UTI, Chlamydia, trochomatis, gonorrhoea, herpes, candidiasis, torchomonas, vaginalis, vulval dermatoses

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2
Q

History questions to ask

A

Frequency?
Do you they wake up in the night to go?
Blood in pain?
Other pain loin, abdo?
ASS: discharge, bleeding (sex, between peroids)
Lumps, bumps rashes- vagina or elsewhere

Sexual Hx:
Sexually active, new partner, does partner have symptoms

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3
Q

What investigations could you do for dysuria?

A

Vulvo-vaginal swab: chlamydia + gonorrhoea NAAT
High vaginal swab: candida, BV, Trichomonas Vaginalis
Endocervical swab: gonorrhoea
MSU: UTI

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4
Q

Names cases of vaginal discharge

A

BV, candidacies, trichomonas vaginalis, gonorrhoea, chlamydia, cervical herpes infection, retained foreign body

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5
Q

Describe clinical presentation of BV, changes on microscopy & TX

A

watery white discharge + fish smell.
pH > 4.5
Microscopy: loss of lactobacilli replaced with small cocoa-bacilli (Usually G. vaginalis)
Tx: Metronidazole

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6
Q

Risk for thrush.

A

pregnancy, diabetes, recent abx

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7
Q

Describe clinical presentation of trichomonas vaginalis

A
Sexual risk (new partner, abroad, partner symptoms)
Malodorous green/yellow discharge often frothy
Vuval burning & discomfort, external dysuria
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8
Q

trichomonas vaginalis

a) appearance of cervix in 2-5%
b) Microscopy
c) How to investigate
d) Tx

A

a) strawberry cervix
b) mobile flagellated protozoa
c) high vaginal swab
d) metronidazole

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9
Q

Clinical presentations of gonorrhoea &chlamydia

A
Sexual risk
Usually asymptomatic 
Abnormal bleeding PCB/IMB
Lower abdo pain
Dysuria 
\+/- purulent discharge
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10
Q

What tests for C & G?
How do you treat C or G
What are the transmission rates?

A

Endocervical & vulvo-vaginal swab: culture & NAAT for N. gonorrhoea

Gonorrhoea:

  • cefixime PO or ceftriaxone 500mg IM
  • 75% transmission

Chlamydia:

  • Azithromycin 1g (single dose)
  • 50% tranmission
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11
Q

Infective causes of post-coital bleeding

A

Chlamydia, gonorrhoea, PID

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12
Q

Hx for PCB

A
Smear History 
Sexual history - sexually active? Changed partner? Symptomatic partner?
Vaginal discharge 
Dysuria 
IMB
Abdominal pain
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13
Q

What signs are you looking out for on examination for PCB

A

Cervical excitation- PID
visible lesions on cervix
vaginal/cervical discharge

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14
Q

Investigations for PCB

A

Vulvo-vaginal swab: Chlamydia + Gonorrhoea NAAT
Endocervical swab: Gonorrhoea culture
Cervical Assessment: Cytology +/- colposcopy

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15
Q

Causes of male dysuria & discharge

A

Infective:
chlamydia (50% asympt)
gonorrhoea (10% asympt)

UTI
If <35 assume STI until proven overwise.

Non-gonorrhoea urethritis (NGU)- inflammation of urethra not caused by gonorrhoea

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16
Q

Investigations

A

Urethral swab: gram stained smear & culture for N. gonorrhoea
First void urine: chlamydia & gonorrhoea NAAT
MID stream urine: test for UTI (e.coli)
Syphilis serology
HIV antibody test
Rectal & pharyngeal swabs: 3 site chlamydia/gonorrhoea testing for MSM

17
Q

Tx Chlamydia

A

Azithromycin 1g single dose or doxycycline 100mg bd 7 days

18
Q

Tx Chlamydia

A

Ceftriazone 500mg IM + Azithromycin PO single dose (Tx chlamydia as co-infection in 50%)

19
Q

Complications of chlamydia

A

Reiter’s syndrome/reactive arthritis

Fitz-hugh curtis syndrome

20
Q

How does reiters syndrome present? Who is it more common in?

A

Arthritis (usually in 1 major joint)
Urethritis (or cervicitis in women)
Uveitis/conjunctivitis

21
Q

What is fitz-hugh curtis syndrome? Who suffers from it?

A

A rare complication of PID. Occurs almost exclusively in women. Inflammation spreads from pelvis to Glisson’s capsule that results in peri-hepatitis.

Presents with:
Pyrexia 
Guarding 
RUQ pain
Abnormal LFTs
22
Q

Which HPV subtypes cause condylomata accuminata

23
Q

What are the usual symptoms of genital warts

A

Normally asymptomatic.
May cause painless, slow growing papillomatous lessons.
Often catch on clothing and may cause external dyspareunia.

24
Q

How do you treat genital warts

A

Aim destroy warts:

  1. Pharmacological
    - Podophyllin paint (weekly)
    - Podophyllin Toxin (2 x daily in 3 day cycle, 4 weeks)
    - Thrichloroacetic acid

Physical

  • Crythotheraoy
  • laster therapy

Use condoms, trace sexual contacts

25
What bacteria cause syphilis. What shape is it?
Treponeumum pallidum | spirochete
26
Describe the clinical stages of syphilis
``` Primary syphilis 3 weeks post infection Painless, solitary ulcer (chancre) Chancre often unnoticed Inguinal lymphadenopathy ``` Secondary syphilis 5 weeks after primary, occurs in first 2 years Proliferation of spirochetes in skin and mucous membranes Palms & soles → rash Most areas (anogenital & axillae) Mouth, throat vagina Generalised lymphadenopathy Genital condyloma lata- Wart like lesions on the genitals Anterior uveitis Inflammation of iris Tertiary syphilis 5 years after initial infection Tertiary syphilis → 40% ppl infected > 2 years Neurosyphilis Dementia Tabes dorsalis Cardiosyphilis syphilitis aortitis Endarteritis obliterans -> aortic aneurysm formation Gummata granuloma-like, most commonly found in liver (gumma hepatis) but can be found in brain, heart, skin, bone & testies.
27
Describe early and late congenital syphilis
Early: skin rash, hepatomegaly & skeletal problems (sabre shin = anteriorly curved shin) Late: Hutchinson Triad: Notched central incisors, blindness, deafness from 8th cranial nerve injury
28
How does syphilis affect the foetus
Crosses placenta
29
Main clinical infections of PID
Pelvic pain, adnexal tenderness, fever and vaginal discharge
30
Other cause of PID than ascending STI infection
Childbirth/TOP