Gustation Flashcards

(44 cards)

1
Q

4 sensory systems which contribute flavor

A
  1. Gustation
  2. Olfactation
  3. Chemesthesis
  4. Mechanosensation
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2
Q

4 cephalic responses toward food

A
  1. Saliva release
  2. Digestive enzyme release
  3. Insulin release
  4. Initiation of peristalsis
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3
Q

What is taste?

A

Gustation (the 5 or 6 sensations)

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4
Q

What is flavor?

A

Adds to taste

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5
Q

Flavors

A
  1. Smell
  2. Temperature
  3. Pungency (pepper or wasabi)
  4. Freshness (menthol or mint)
  5. Texture
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6
Q

6 different tastes

A
  1. Sweet
  2. Umami
  3. Bitter
  4. Sour
  5. Salty
  6. Fatty
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7
Q

Chemesthesis: irritants are perceived as?

A
  1. Hot/spicy
  2. Cool/fresh
  3. Pricking
  4. Burning
  5. Stinging
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8
Q

3 nn. in oral cavity

A
  1. CN VII (facial - chorda tympani)
  2. CN IX (glossopharyngeal)
  3. CN X (vagus)
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9
Q

Taste buds on tip of tongue

A

CN VII (facial n. - chorda tympani)

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10
Q

Taste buds in back of tongue

A

CN IX (glossopharyngeal)

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11
Q

Taste buds of epiglottis

A

CN X (vagus)

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12
Q

Role of CN V (trigeminal) in oral and nasal cavity

A

Somato-sensory n. fibers in oronasal cavity

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13
Q

1 receptor cell expresses receptors for __ taste category

A

1 taste category

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14
Q

____ cells per taste bud

A

20-100

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15
Q

4 ways to evaluate food

A
  1. Caloric content
  2. Poison
  3. Rotten/unripe
  4. Electrolyte balance
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16
Q

Ways to taste caloric content

A
  1. Carbohydrate (sweet)
  2. Proteins (AAs)
  3. Fat (FA)
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17
Q

Poison tastes?

A

Bitter

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18
Q

Unripe/rotten foods taste?

A

Sour (pH balance)

19
Q

Electrolyte balance tastes?

20
Q

Taste buds contain what 4 types of cells?

A
  1. Glial cells
  2. Receptor cells
  3. Presynaptic cells
  4. Basal cels
21
Q

Role of glial cells

A

Ensheath type II (receptor) cells and express ecto-ATPase

22
Q

Role of ecto-ATPase

A

Limits extracellular ATP

23
Q

Receptor cells

A
  1. Subtypes for sweet, umami, bitter and fatty
  2. Release ATP via channels in responses to ligand
  3. Does not form synapses with gustatory afferents
24
Q

Presynaptic cells

A
  1. Subtypes for salty and acid
  2. Release serotonin and norep
  3. Do form synapses with gustatory afferents
25
Basal cells
Stem cells for taste bud regeneration (taste cell turnover is 2 weeks)
26
How do receptor cells directly activate gustatory afferents?
ATP release
27
How do receptor cells indirectly activate gustatory afferents?
Presynaptic cells activate to release serotonin and norep in response to ATP
28
Type III cells Taste: Receptor: Transmitter
Salty and sour Ion-channel Vesicular serotonin & NE
29
Type II cells Taste: Receptor: Transmitter
Sweet, umami, fatty and bitter GPCR Non-vesicular ATP (unknown for fatty)
30
Type I cells
Glial
31
Type II cells
Receptor
32
Type III cells
Presynaptic
33
Type IV cells
Basal
34
High salt activates?
Sour or bitter
35
Signal transduction for salty and sour tastes
1. Ion channel 2. Depol. 3. AP 3. Vesicular release of 5HT or NE
36
Signal transduction for sweet, umami, bitter and fatty tastes
1. GPCR 2. Gustducin 3. PLCB2 4. TRPM5 5. Depol. 6. AP 7. Non-vesicular release of ATP
37
PLCB2
Phosphlipase C, B2
38
TRPM5
Transient receptor potential, melastatin family, member 5
39
Chemsthesis sensors
TRPxx or KCNKx
40
TRPA1
Cold
41
TRPM8
Cool
42
TRPV3
Warm
43
TRPV1
Hot
44
KCNKx
Tingling