GYNE Benign Disorders of the Upper and Lower Genital Tract, Blueprints Flashcards Preview

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Flashcards in GYNE Benign Disorders of the Upper and Lower Genital Tract, Blueprints Deck (230)
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1

Most common cause of labial fusion

Exogenous androgen

2

Most common form of enzymatic deficiency

21-hydroxylase deficiency

3

21-hydroxylase deficiency: Associated condition

Congenital adrenal hyperplasia (CAH)

4

Congenital adrenal hyperplasia (CAH): Hormone elevated

17α-hydroxyprogesterone

5

Congenital adrenal hyperplasia (CAH): Serum cortisol, increased vs decreased

Decreased

6

Congenital adrenal hyperplasia (CAH): Treatment

Exogenous cortisol

7

Congenital adrenal hyperplasia (CAH): Mechanism of exogenous cortisol

Negative feedback on pituitary > decrease ACTH > inhibition of adrenal gland stimulation > decrease in androgens

8

Primary amenorrhea + cyclic pelvic pain: Condition

1) Imperforate hymen
2) Transverse vaginal septum
3) Vaginal atresia

9

Accumulation of menstrual flow behind the hymen in the vagina

Hematocolpos

10

The caudal portion of the Müllerian ducts develops into

Uterus and upper vagina

11

Structure that must be canalised for normal vagina to form

Mullerian tubercle

12

Failure of mullein tubercle to canalise results in

Transverse vaginal septum

13

Most common site of transverse vaginal septum

Between upper 1/3 and lower 2/3

14

Occurs when the lower vagina is replaced by fibrous tissue and on PE reveals a vaginal dimple

Vaginal atresia

15

Vaginal atresia, management

Vaginal pull-through

16

Congenital absence of vagina and absence or hypoplasia of all or part of the cervix, uterus, and fallopian tubes

Vaginal agenesis

17

Vaginal agenesis is aka

Meyer-Rokitansky-Kuster-Hauser syndrome

18

T/F Ovary is hypoplastic in vaginal agenesis

F, normal

19

Vaginal agenesis: T/F Normal external genitalia

T

20

Vaginal agenesis: T/F Normal secondary sexual characteristics (breast development, axillary, and pubic hair)

T

21

Vaginal agenesis: T/F Normal ovarian function

T

22

Vaginal agenesis: T/F Phenotypically female

T

23

Vaginal agenesis: T/F Genotypically female

T

24

Vaginal agenesis: Management

1) Non-surgical with the use of dilators
2) Surgical

25

Vaginal agenesis: Most common surgical procedure used

McIndoe procedure

26

Vaginal agenesis: T/F Will be unable to carry a pregnancy

T

27

Inflammatory dermatosis that is associated with a risk for vulvar skin Ca in postmenopausal women

Lichen sclerosis

28

Inflammatory dermatosis associated with vaginal adhesions and erosive vaginitis

Lichen planus

29

T/F Lichen planis carries a risk of vulvar skin cancer

T

30

Inflammatory dermatosis that generally occurs in women in their 50s and 60s

Lichen planus