Haematology Flashcards
1
Q
What are the indications to start chemotherapy in CLL?
A
Weightloss of 10%
Extreme fatigue
Fever
Night sweats
Progressive marrow failure
Autoimmune anaemia
Autoimmune thrombocytopaenia
Massive lymphadenopathy
Increase in lymphocytes >50% in 6/12
2
Q
What is the chemo regime for CLL?
A
Fludarabine
Rituximab
Cyclophosphamide
3
Q
Which factor is affected in acquired haemophilia?
What does clotting show?
Who is likely to get it?
A
Factor 8
Prolonged APTT
Those with autoimmune conditions or malignancy
4
Q
What is the pentad of TTP?
A
Fever
AKI
cérébral dysfunction
Thrombocytopaenia
Microangiopathic haemolytic anaemia: fragmented blood cells seen on film
5
Q
Treatment of ITP
A
Oral pred
If bleeding - IV immunoglobulin
6
Q
Treatment of HIT
A
Argatroban
