Haemoglobin And Mass Transport In Animals Flashcards

(18 cards)

1
Q

What’re the characteristics of haemoglobin ?

A
  1. Quaternary protein (4 polypeptide chains)
  2. Each chain has haem group
  3. Haem group contains iron ion
  4. Iron ion associates with O2 molecule
  5. Haemoglobin carry 4 O2
  6. O2 and haemoglobin form to make oxyhaemoglobin
  7. Amount of O2 combined to haemoglobin refers to % saturation of haemoglobin
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2
Q

Why is O2 dissociation curve S shaped ?.

A
  1. First O2 binds to iron ion slowly so start of curve isn’t steep
  2. Causes tertiary structure of haemoglobin to change
  3. This exposes remaining O2 binding sites so easier for rest if O2 to bind making curve steep
  4. Curves flattens when most of haemoglobin has been saturated
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3
Q

What is the circulatory system made of ?

A

Heart and blood vessels

Double pump system

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4
Q

What does vena cava do ?

A

Carry blood from body to right atrium

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5
Q

What’s does pulmonary artery do ?

A

Carry blood from right ventricle to lungs

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6
Q

What does pulmonary vein do ?

A

Carry blood from lungs to left atrium

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7
Q

What does aorta do ?

A

Carry blood from left ventricle to rest of body

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8
Q

What does renal artery do ?

A

Carry blood from heart to kidney

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9
Q

What does renal vein do ?

A

Carry blood from kidney to heart

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10
Q

What do coronary arteries do ?

A

Supply blood to cardio muscle

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11
Q

What are the stages of cardiac cycle ?

A
  1. VENTRICLES RELAX, ATRIA CONTRACT
  2. VENTRICLES CONTRACT, ATRIA RELAX
  3. VENTRICLE RELAX, ATRIA RELAX
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12
Q

What’s cardiac output ?

A

Volume of blood pumped out left ventricle per min

Stroke volume x heart rate

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13
Q

What’s the role and features of arteries ?

A

ROLE: carry blood away from heart
FEATURES:
- thick muscle wall withstands high pressure
- elastic tissue to stretch when ventricles contract and recoil when ventricles relaxes
- endothelium to reduce friction
- aorta wall has fibrous protein to withstand high pressure

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14
Q

What’s the role and features of arterioles ?

A

ROLE: carry blood from arteries to capillaries
FEATURES:
- muscular layer thicker to allow for contraction and constriction of lumen
- thinner elastic layer as pressure is lower

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15
Q

What’s the role and features of veins ?

A

ROLE: carry blood to heart
FEATURES:
- thin muscle layer
- thinner elastic elastic layer
- valves to prevent back flow
- skeletal muscles contact veins compress increasing pressure of blood in them
- wide lumen to reduce friction

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16
Q

What’s the role and features of capillaries ?

A

ROLE: exchange substances between cells and capillaries
FEATURES:
- one cell thick
- walls are permeable
- fenestrations to allow large molecules to leave
- narrow lumen reduce flow rate giving more time for diffusion
- endothelium cells smooth and flat reduced friction and shortens diffusion pathway

17
Q

How is tissue fluid formed ?

A
  1. Change in BP from high to low from artery to vein forms hydrostatic pressure
  2. Fluid is made from blood plasma containing amino acids, glucose, ions etc and is forced out capillaries into space around cells
  3. Large molecules such as platelets, plasma proteins remain in capillaries
  4. Blood love towards venous side of capillary and water potential decreases
  5. Higher water potential in tissues fluid means it goes back into capillary via osmosis
  6. Any remaining tissue fluid that’s not been re absorbed in capillaries is drained via lymphatic capillaries
18
Q

What are risks faces for cardiovascular disease ?

A

Gender
Age
Genetics
Stress
Smoking a