Haemoglobin And Mass Transport In Animals Flashcards
(18 cards)
What’re the characteristics of haemoglobin ?
- Quaternary protein (4 polypeptide chains)
- Each chain has haem group
- Haem group contains iron ion
- Iron ion associates with O2 molecule
- Haemoglobin carry 4 O2
- O2 and haemoglobin form to make oxyhaemoglobin
- Amount of O2 combined to haemoglobin refers to % saturation of haemoglobin
Why is O2 dissociation curve S shaped ?.
- First O2 binds to iron ion slowly so start of curve isn’t steep
- Causes tertiary structure of haemoglobin to change
- This exposes remaining O2 binding sites so easier for rest if O2 to bind making curve steep
- Curves flattens when most of haemoglobin has been saturated
What is the circulatory system made of ?
Heart and blood vessels
Double pump system
What does vena cava do ?
Carry blood from body to right atrium
What’s does pulmonary artery do ?
Carry blood from right ventricle to lungs
What does pulmonary vein do ?
Carry blood from lungs to left atrium
What does aorta do ?
Carry blood from left ventricle to rest of body
What does renal artery do ?
Carry blood from heart to kidney
What does renal vein do ?
Carry blood from kidney to heart
What do coronary arteries do ?
Supply blood to cardio muscle
What are the stages of cardiac cycle ?
- VENTRICLES RELAX, ATRIA CONTRACT
- VENTRICLES CONTRACT, ATRIA RELAX
- VENTRICLE RELAX, ATRIA RELAX
What’s cardiac output ?
Volume of blood pumped out left ventricle per min
Stroke volume x heart rate
What’s the role and features of arteries ?
ROLE: carry blood away from heart
FEATURES:
- thick muscle wall withstands high pressure
- elastic tissue to stretch when ventricles contract and recoil when ventricles relaxes
- endothelium to reduce friction
- aorta wall has fibrous protein to withstand high pressure
What’s the role and features of arterioles ?
ROLE: carry blood from arteries to capillaries
FEATURES:
- muscular layer thicker to allow for contraction and constriction of lumen
- thinner elastic layer as pressure is lower
What’s the role and features of veins ?
ROLE: carry blood to heart
FEATURES:
- thin muscle layer
- thinner elastic elastic layer
- valves to prevent back flow
- skeletal muscles contact veins compress increasing pressure of blood in them
- wide lumen to reduce friction
What’s the role and features of capillaries ?
ROLE: exchange substances between cells and capillaries
FEATURES:
- one cell thick
- walls are permeable
- fenestrations to allow large molecules to leave
- narrow lumen reduce flow rate giving more time for diffusion
- endothelium cells smooth and flat reduced friction and shortens diffusion pathway
How is tissue fluid formed ?
- Change in BP from high to low from artery to vein forms hydrostatic pressure
- Fluid is made from blood plasma containing amino acids, glucose, ions etc and is forced out capillaries into space around cells
- Large molecules such as platelets, plasma proteins remain in capillaries
- Blood love towards venous side of capillary and water potential decreases
- Higher water potential in tissues fluid means it goes back into capillary via osmosis
- Any remaining tissue fluid that’s not been re absorbed in capillaries is drained via lymphatic capillaries
What are risks faces for cardiovascular disease ?
Gender
Age
Genetics
Stress
Smoking a