Hard metals Flashcards

(48 cards)

1
Q

What causes fibrosis of the lungs?

A

Silica

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2
Q

What abuse drug causes respiratory depression + endocardidtis

A

Opiates

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3
Q

Mineral dusts (coal dust, silica, asbestos, beryllium) cause?

A

Pneumonconioses

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4
Q

What are 2 types of organic solvents and what do they cause?

A

Chloroform + carbon tetrachloride

CNS depression + coma

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5
Q

What does cadmidium posioning cause?

A

renal tubular damage + skeletal abnormalities associated with calcium loss

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6
Q

Chronic aspirin posioning causes?

A

Analgesic nephropathy, hearing problems

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7
Q

Radon gas is a form of?

A

Uranium

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8
Q

Nitrosamines + nitrosamides cause?

A

Gastric carcinoma

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9
Q

Acetaminophen poisoning causes?

A

Acute liver failure, centrilobular necrosis

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10
Q

What disease is from cadmium posioning?

A

Itai-Itai

Japan - osteoporosis + osteomalcia

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11
Q

What causes heart disease?

A

CO + lead

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12
Q

Asbestosis causes?

A

Mesothelioma

(ferrunginous bodies)

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13
Q

Tachycardia, HTN, and peripheral vasoconstriction are caused by?

A

Cocaine

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14
Q

Where is cadmium found?

A

plants = food

mining

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15
Q

Hyperpigmentation + hyperkeratosis

A

Arsenic

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16
Q

What causes chloracne (dermatitis)? Who got this after poisoning?

A

Dioxins + PCBs

Viktor Yushenko

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17
Q

What amount of radiation hits the brain and is 100% lethal?

A

>50 Sv

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18
Q

What outdoor pollutant causes decreased lung function + lung inflammation + decreased exercise capacity and is largely mediated by free radicals?

A

Ozone

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19
Q

What is the usual dosage for radiation? Causes hair loss, vomiting

A

2-10 Sv

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20
Q

Where is arsenic found?

A

Naturually in soil + water

21
Q

If you smoke + are on oral contraceptives what can you get?

A

hepatic adenoma (benign)

22
Q

Aflatoxin causes?

A

Hepatocellular carcinoma

23
Q

High animal fat + low fiber causes?

24
Q

What causes COPD?

25
Which drug deposits in skin and causes blue/gray discoloration/rash?
Antibiotic minocycline
26
Mercury causes what disease?
Minamata disease --\> major CNS damage
27
What causes leukemia?
Benzene
28
Male + female infertility/stillbirths are caused by?
Lead
29
What positively correlates to breast cancer?
Total dietary fat
30
Lichtenberg figures are from what?
Lightning strikes
31
Vit. C + E + B carotenes + selenium =
Anti-carcinogenic from anti-oxidant properties
32
What causes liver angiosarcoma?
Vinyl chloride
33
Pet dander, fungi, molds are types of?
Bioaresols
34
Mercury + lead + arsenic cause:
Peripheral neuropathies
35
Why is sulfur dioxide more dangerous than ozone?
It combines w/ ozone + particulate matter (witches brew) and causes burning sensation in nose + throat and difficulty breathing. SD is found inpower plants, paper mills
36
Which outdoor pollutant causes increased respiratory symptoms + mortality in COPD patients and increased hospitalilations in asthma?
Sulfur Dioxide
37
Malignant hyperthermia = what gene?
RYR1
38
What causes lung cancer?
Radon, asbestos, silica
39
What constitues hypothermia?
Body temp less than 90
40
Benzene posioning causes what?
Bone marrow aplasia --\> acute myeloid leukemia
41
What is the definition of particulate matter (soot)?
Fine or ultrafine particles less than 10 um in diameter.
42
What bacteria virtually colonizes all burns?
Pseudomonas aeruginosa
43
Pesticides like DDT + PCBs + dioxin do what?
Disrupt hormonal balance
44
How do you get mercury posioning?
Fish or mercury vapors in dental amalgams?
45
Ataxic gait + renal toxicity are caused by?
Mercury
46
Rash around eyes, nose, anus Anorexia
Zinc deficiency
47
Goiter and hypothyroidism
Iodine deficiency
48