Hb, Structure, Properties And Functions

Question 1

How many haemoglobin molecules per RBC?

Answer 1

640 million

Question 2

Composition of adult haemoglobin

Answer 2

2 alpha and 2 beta chains

Question 3

Molecular weight of Haemoglobin

Answer 3

68000 or 64500 daltons

Question 4

Other types of hemoglobin are?

Answer 4

HbF and HbA²

Question 5

Concentration of Haemoglobin

Answer 5

Adult male : 13.5-17.5 g/dL
Adult female: 12-15 g/dL

Question 6

How many amino Acids on alpha and beta chains of Haemoglobin?

Answer 6

Alpha chain- 141 AA
Beta chain - 146 AA

Question 7

Major form of Haemoglobin in adults and children over 7 months?

Answer 7

HbA¹

Question 8

What percentage of total haemoglobin is HbA²?

Answer 8

2-3%

Question 9

Subunits of fetal Haemoglobin?

Answer 9

2 alpha and 2 gamma

Question 10

Embryo haemoglobin include?

Answer 10

Hb Gower- 1
Hb Gower-2 (only one with 2 alpha)
Hb Portland ( only one with gamma)

Question 11

Derivatives of Haemoglobin

Answer 11

oxyHb
deoxyHb
metHb
HbCO
HbCO²
HbA1c

Question 12

Why is measurement of blood HbA1c useful?

Answer 12

To get info about long term control of glycemia

Question 14

Haem and globin are joined by what bond?

Answer 14

Non covalent bonds chemically