Surfactants Flashcards
(10 cards)
1
Q
Key surfactant proteins?
A
SP -A
SP-B
SP-C
SP- D
2
Q
Classes of Lipids found in pulmonary surfactant?
A
Phospholipids
Triglycerides
Cholesterol
Fatty Acids
3
Q
When does lamellar bodies appear in cytoplasm?
A
At about 20 weeks gestation
4
Q
Full term infants have a storage pool of?
A
100mg/kg
5
Q
Preterm infants have a storage pool of?
A
4-5mg/kg
6
Q
Half life of alveolar surfactant once secreted
A
5-10 hours
7
Q
What percentage of surfactant is secreted back into the type 2 pneumocyte?
A
90%
8
Q
What percentage is taken up by alveolar macrophages and digested?
A
9
Q
Most abundant SP-C protein?
A
SP_A
10
Q
A
