HC1 female Flashcards
(27 cards)
3 Functions of Ovaries
- Production of immature female gametes
(oocytes) - Secretion of female sex hormones:
estrogens, progestins
* Feedback control uterine cycle - Secretion of inhibin:
* feedback control of pituitary FSH
Ovaries
Production of oocytes
Female sex hormones, estrogen and progesterone
Secretion of inhibin, involved in the feedback control of FSH
where are the ocytes are produced in
cortex (=outer rim) of ovary.
Oocytes are produced in a
follicle (=a group of cells)
broad ligament
ovaries, uterine tubes, and uterus are enclosed within an extensive mesentery. It attaches to the sides and floor of the pelvic cavity, continuous with parietal peritoneum
Mesovarium
supports and stabilizes the position of each ovary
ovarian hilum
ovary attaches here to blood vessels and the mesovarium
Germinal epithelium
covers the surface of each ovary, consists of a layer of columnar epithelial cellls that overlies a dense connective tissue layer called the tunica albuginea
uterine tubes
hollow muscular cylinder measuring about 13cm
uterine tubes are divided
- the infundibulum, end closest to the ovaries, fingerlike projections that extend into the pelvic cavity (fibriae)
- the ampulla, middle region, thickness increases going towards uterus
- Isthmus, a short region connected to the uterine wall
uterine tube is made of
epithelium lining
ciliated columnar epithelial cells with scattered mucin-secreting cells, smooth muscle layers
transport of oocyte in the uterine tube
ciliary movement and peristaltic contractions
what kind of environment is the uterine tubes
nutrition rich, lipids and glycogen for both oocytes and sperm
where does fertilization occur
near the boundary between the ampulla and isthmus of the uterine tube
Uterus tasks
Muscular organ
* Mechanical protection
* Nutritional support
* Waste removal for the
developing embryo and fetus
* Supported by the broad ligament and 3 pairs of suspensory
ligaments (uterosacral, round, lateral ligaments)
What are the layers of the uterine wall
Uterus wall:
* Endometrium (10%)–
a thin, inner, glandular mucosa
* Myometrium (~90%) – outer muscular layer
* Perimetrium – an incomplete serosa (smooth membrane) continuous with the peritoneum
functional layers of the uterine
basic layer, adjacemt to the myometrium, there’s uterine glands and the endometrical thickness. This layer undergoes a lot of changes changes during uterine cycle
Repeating series of changes in the endometrium
- Basilar zone remains relatively constant
- Continues from menarche (first cycle) to menopause
- Menses
- Degeneration of endometrium (functional layer)
- =>Menstruation
- Proliferative phase
- Restoration of the endometrium
- Secretory phase
- Endometrial glands enlarge and accelerate their rates of secretion
Oogenesis
is the production of gametes called oocytes, oogenesis takes place in the ovaries within structures called follicles.
Ovarian cycle
the events od oocyte maturation which takes about a month
Uterine cycle
series of events that prepare the uterus for implantation of a fertilized oocyte
what happens in fetal development regarding to oogenesis
oogonia which are stem cells go through mitosis during Fetal development producing diploid primary oocytes, after 5 months of development, fetal ovaries contain an estimated 7 million primary oocytes, at birth 2 million, remaining primary oocytes undergo meiosis I and stay in prophase I until puberty → resumes and completes meiosis I in response to LH
atresia
degeneration of oocytes before puberty (400k)
puberty oocyte
resumes meiosis I and producing haploid secondary oocytes. Oogenesis produces one secondary oocyte is unevenly distributed during the original cytoplasm, and two or three polar bodies, nonfunctional cell that later disintegrate
Oogenesis steps
- Mitosis of oogonium, oogonium → 1. oogonium and 1. primary oocyte 2n
- Meiosis I, 3-7month of the Fetal Development, the primary oocytes prepare to undergo meiosis → prophase I, at puberty the rise of FSH trigger the starit of the ovarian cycle→triggers meiosis I to finish→fisrt polar body and a secondary oocyte
- Meiosis II, ovulation releaces a secondary oocyte which is in metaphase II, at fertilization another polar body forms and the oocyte is then called mature ovum