HEAD AND NECK Flashcards

(219 cards)

1
Q

Tonsilitis imaging and complications

A

tonsilar enlargement, touching in the midline
contrast enhancing without focal fluid
parapharyngeal fat stranding

complications
- peritonsillar abscess
- intratonsillar abscess
- extension to deep spaces
- otitis media

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2
Q

Tonsilitis ddx

A

SCC
Lymphoma

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3
Q

Tonsillar abscess imaging

A

central hypoattenuation and rim enhancement
tonsillar tissue surrounding

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4
Q

Peritonsillar abscess imaging

A

rim enhancing fluid adjacent to enlarged and inflamed tonsil

complications;
- retropharyngeal effusion
- retropharyngeal abscess
- lemierre syndrome (septic thrombophlebitis IJV)

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5
Q

Lemierre syndrome is

A

thrombophlebitis of the IJC with distant sepsis in the setting of intial oropharyngeal infection (pharyngitis, tonsilllitis, peritonsilar abscess, retropharyngeal abscess).

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6
Q

Retropharyngeal abscess is (and causes)

A

potentially life threating infection involving the retropharyngeal space.

causes
- complication of primary infection elsewhere such as nasopharync, paranasal sinuses, middle ear
- or oropharyngeal infections, discitis, osteomyelitis, penetrating trauma

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7
Q

Retropharyngeal abscess complications

A
  • posterior extension to prevert, disc/vert, epidural
  • lateral extension to carotid and jugular
  • anteiror compression airway
  • inferior extension to mediastinum
    sepsis
  • grisel syndroime
  • lemierre synrome
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8
Q

Retropharyngeral abscess ddx

A

retropharyngeal cellulitis
retropharyngeal oedema
prevertebral abscess
retropharyngeal haematoma
acute calcific prevertebral tendiintis
pseudothickening

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9
Q

Grisel syndrome is

A

torticollis of the atlantooaxial joint from inflammatory ligamentous laxity in head and neck infection

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10
Q

Zenker diverticulum is

A

posterior outpouch of the hypopharynx, proximal to the upper oesophageal sphincter through a weakness in the muscle layer called killian dehiscence (normal cleavage plane between the two parts of the inferior constrictor)

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11
Q

zenkers imaging

A

midline posterior diverticulum at C5/C6
may be transient

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12
Q

Killian Jameison diverticulum is

A

an outpouching of mucosa through the killian jamieson space.

located below cricopharyngeus, anteriorly and laterally. typically left sided, can be bilateral. smaller, less frequent and normally asx compared to zenkys

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13
Q

Head and neck SCC pathophysiology

A

HPV important risk factor, particularly 16, 18, 31
Stronger assoc in some sites, eg. oropharynx
Overexpression of p16 used as surrogate marker

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14
Q

Oral cavity SCC staging

A

TX cant see
Tis

T1
- <2cm greatest dimension, DOI <5mm

T2
- <2cm DOI 5-10mm OR
- 2-4cm DOI <10mm

T3
- DOI >10mm, or
- tumour >4cm DOI <10mm

T4a moderately advanced
- >4cm DOI >10mm OR
- invades local structures

T4b very advanced
- invades masticator space, pterygoid plates, skull cases and/or encases ICA

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15
Q

Oral cavity SCC ddx

A

other malig
- lymphoma
- minor salivary gland
- sarcoma

infection
- teeth
- infected rannula

radionecrosis mandible

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16
Q

Cervical node staging

A

NX

N0

N1
- single ipsilateral node <3cm no ENE

N2a
- single ipsi 3-6cm, no ENE
N2b
- multiple ipsi, <6cm, no ENE
N2c
- bilateral or contralatertal nodes <6cm, no ENE

N3a
- node >6cm, no ENE
N3b
- node with clinically overt ENE

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17
Q

Oral cavity SCC usually in

A

lower lip, oral tongue, FOM

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18
Q

Oropharyngeal SCC overview

A

subcatergorised into HPV/P16 positive or negative. P16 associted occurs in younger but responds better to chemoradiotherapy and carry a better prognosis

location; tonsil, base of tongue, soft palate
although can be anywhere
nb; lingual surface epiglottis coiunts as larynx, soft plate nasopharynx

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19
Q

P16 negative oropharyngeal SCC staging

A

Tx
Tis

T1
- <2cm

T2
- 2-4cm

T3
- > 4cm or
- extension to lingula surface epiglottis

T4a moderate
- larynx
- extrinsix tongue mm
- medial pterygoid
- hard palate
- mandible

T4b very advanced - ICA or any of the following
- lateral pterygoid
- pterygoid plates
- lateral nasopharynx
- skull base

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20
Q

P16 postive oropharyngeal SCC staging

A

T0

T1
- <2cm

T2
- 2-4 cm

T3
- >4cm OR
- extension to lingual surface epiglottis

T4
- larynx, except lingual epiglottis
- extrinsic mm tongue
- medial pterygoid
- hard palate
- mandible

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21
Q

Hypopharyngeal SCC path

A

bad for you - worst proggy of all

most commonly at piriform sinus, but can be posterior wall or post cricoid/pharyngooesopahgeal junction

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22
Q

Hypopharynx SCC staging

A

TX
TIS

T1
- one subsite AND/OR
- <2cm

T2
- extends into adjacent subsite or site AND/OR
- 2-4cm with hemilarynx fixation

T3
- tumour >4cm OR
- clinical fixation hemilarynx OR
- extension to oesophageal mucosa

T4a moderate
- thyroid cartilage
- cricoid cartilage
- hyoid bone
- thyroid gland
- oesophageal muscle
- central compartment soft tissue

T4b
- encases carotid artery OR
- mediastinum/prevertebral

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23
Q

Nasopharyngeal carcinoma path

A

of squamous origin
some types strongly assoc with EBV

types
- keratinising
- non keratinising
- basaloid squamous

non kerat and basaloid squamous assoc with EBV

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24
Q

NPC imaging

A

Fossa or rosemuller ionitially effaces
Level 2 and 5 nodes commonly involved

CT
- soft tissue mass fossa of rosenmuller
- smaller confined by pharyngobasilar fascia
- larger can extend in any direction
- heterogenous enhancement

MR
T1 iso to muscle
T2 iso to hyper to muscle, fluid in middle ear
C+ heterogenous prominent. ?perineural invasion

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25
NPC ddx
DDX small - adenoidal tissue - nasopharyngeal lymphoma - low grade or other early primary malig DDX large - mets - adenoid cystic - plasmacytoma - fibrosiing pseudotumour - lymphom - chordoma - chondrosarcoma - meningioma - JNA
26
NPC staging
Tx T0 - EBV positive node TIS T1 - confined to nasopharynx OR - extends to oropharynx or nasal cavity wihtout parapharyngeal invovlement T2 - extends to paraphryngeal space AND OR - medial pterygoid, lateral pterygoid, prevertbral muscles T3 - skull base, cervical vertebra, pterydoid plates, pterygopalatine fossa, paranasal sinuses T4 - intracranial - cranial nerves - hypopharynx - orbit - parotid - soft tissue beyond lateral pterygoid
27
Larynx SCC staging
T1-3 defined by site SUUPRAGLOTTIS T1 limited to one subsite, normal cord mobility - suprahyoid epi - aryepiglottic folds - infrahyoid epiglottis - false cords - arytenoids T2 invades mucosa adjacent area, normal cord mobility - subsite supraglottis - glottis - region outside supraglottis; base of tongue, vallecula, medial wall pyriform sinus T3 limited to larynx with vocal cord fixation and/or invasion of - innner cortex thyroid cart - paraglottic space - preepiglottic space - post cricoid area GLOTTIS T1 limited to cord with normal mobility T1a one cord T1b both cords T2 extends to supra or subglottis AND/OR impaired vocal cord mobility T3 larynx with cord fixation AND/OR invasion of paraglottix space AND OR inner cortex thyroid cartilage SUBGLOTTIS T1 limited to subglottis T2 extneds to cords without fixation T3 limited to larynx with cord fixation AND OR invasion of paraglottis AND OR inner cortex thyroid cart SAME FOR ALL T4a - outer cortex thyroid cart - cricoid cart - tissue beyond larynx T4b - mediastinum - prevertebral space - encases carotid artery
28
Ranula is a
rare benign acquired cyst at the floor of mouth. result from obstruction of a sublingual gland or adjacent minor gland. can be simple or plunging - simple: confined to sublingual space - plunging: extends to submandibular space, either around posterio edge of mylohyoid or through a deficiency, mylohyoid boutonniere
29
Ranula imaging
Connection to sublingual space US - thin walled, cystic lesions - can be complex if infected CT - thin walled fluid attenuation. can have superimposed infection. MR T1 low T2 high C+ wall can enhance DDX - dermoid/epidermoid - cystic hygroma - cervical abscess - thyroglossal duct cyst - 2nd branchial cleft cyst
30
Cricopharyngeal spasm is (and imaging and complications)
may present as a cause of dysphagia presents as a cricopharyngeal bar at C5/6 on fluoro complcations - hypertrophy - zenkers
31
Vocal cord paresis causes and imaging
causes - neck/superior thoracic mass, aortic path, osteophytes - masses affecting vagus nerve - iatrogenic injury - idiopathic - blunt and penetrating trauma - congenital anomalies eg meningomyelocele, chiari, hydroceph imaging - enlarged piriform sinus - medialisation aryepiglottic fold - enlarged laryngeal ventricle - atrophy thyroarytenoid muscle - anteromedial deviation arytenoid cartilage - abducted vocal cordon breath hold, compensatory medial bowing of hte contralateral
32
Subglottic/tracheal stenosis
Post intubation Sparing posterior wall - Relapsing polychondritis (smooth) - Tracheobronchiopathia osteochondroplastic (nodular) Involving posterior wall - amyloid - wegners - sarcoid
33
Relapsing polychondritis is
a rare multisystem disease characterised by recurrent inflammation of the cartilaginous structures in the body. Airways commonly involved
34
Tracheobronchopathia osteochondroplastica is
a rare idiopathic non neoplastic airway abnormality, with nodular thickening of the cartilage. can be cartilaginous or calcified.
35
Acute sinusitis imaging
Non specific, can be seen in asx patients XR - opacification CT - peripehral mucosal thickening - gas fluid level - OMC obstruction - maxillary dentition MR T1 mucosa iso, fluid hypo T2 hyper C+ mucosa enhances Complications - subperiosteal abscess incl orbitla and pott puffy - dural sinus thrombosis - meningitis empyema, abscess
36
Chronic sinusitis imaging
infection over 12 weeks. commonly assoc anatomical variants incl - concha bullosa - posterior nasal septal deviations - uncinate process variations - paradoxical middle turbinate - agger nasi cells - haller cells sclerotic thickening bone from prolonged mucoperiosteal reaction. intrasinus calc may be present. five main patterns; 1. OMC: max,. ant eth, front 2. infundibular: isolated ethmoid infundibulum and/or maxillary sinus ostium 3. sphenoethmoidal recess: sphenoid and posterior eth 4. sinonasal polyposis 5. sporadic
37
Concha bullosa is
pneumatisation of the middle turbinate, commonly assoc with septal deviation
38
Paradoxical middle turbinate is
inferomedially curved middle turbinate edge with concave surface facing the nasal septum, usually bilat
39
Agger nasi cells are
most anterior ethmoidal air cells - anterolateral and inferior to frontal recess - anterior and above attachment of middle turbinate - within the lacrimal bone, related laterally to orbit, lacrimal sac, NL duct
40
Supraorbital cells are
anterior ethmoidal air cells extending posteriorly and superiorly over the orbit from the frontal recess
41
Sphenoethmoidal air cell/Onodi air cell
Posterior ethmoidal air cell, extends posteriorly to lie superolateral to sphenoid sinus in close prox to ICA and optic nerve. often extends to anterior clinoid process.
42
Haller cells are
ethmoid air cells lateral to the maxilloethmoidal suture along the inferomedial orbital floor
43
Fungal sinusitis classification
Non invasive; hypae do not invade mucosa - allergic fungal - sinus fungal mycetoma Invasive; hypae in mucosa and beyond - acute invasive - chronic invasive - granulomatous invasive
44
Allergic fungal sinusitis imaging and ddx
CT - sinus opacification - central serpinginous hyperdense materal - expangion - remodelling/thinning - erosion MR - T1 hypo mucosa, variable T2 - hyperintense mucosa - low centrally C+ mucosa enhancement DDX sinonasal polyposis sinus fungal mycetoma - usually one side, no hyperimmune response sinonasal mucocele - same chronic expansive features, no erosions non hodgkins lymphoma - homogenous
45
Paransal sinus mycetoma imaging
CT - typically single sinus, common is maxillary then sphenoid - soft tissue with or without calcs - can have post obstructive/chronic sinusitis features - no bone erosions MR T1 low T2 low C+ mucosa might enhance DDX allergic fungal sinusitis chronic invasive fungal sinusitis - bone erosion paranasal sinus mucocele sinonasal inverted papilloma
46
Acute invasive fungal sinusitis is
most aggressive form fungal sinus disease. seen mostly in immunocompromised patients. aspergillus in neutropaenia and zygomycetes in diabetes
47
Acute invasive fungal sinusitis imaging
CT - NO internal hyperdensity, unlike chronic - mucosal thickening - opacification of the sinus - bone destruction - fat stranding outside sinus perimeter, including periantral fat stranding MR T1 intermediate to low T2 fungal mass low to intermediate - black turbinate sign; non enhancement nasal turbinates from invasion/necrosis C+ absent mucosal enhancement suggests necrosis, invasion Assess in particular for - stranding of the periantral fat - intraorbital, masticator, pterygopalaitine - subtle enhancement - leptomeningeal enhancement - intracranial granulomas - cavernous sinus thrombosis - carotid pseudoaneurysm - cerebrtits/abscess
48
Chronic invasive fungal sinusitis imaging
more than 12 weeks CT - homogenous opacification iso to hyper - lack of expansion - mottled bone destruction - focal bone erosion and extrasinus component - sclerotic change MR - iso to hypo - usually marked hypo
49
Granulomatous invasive fungal sinusitis is
a form of invasive fungal sinusitis large expansive mass with bone destruction and local invasion. CT bone destruction hyperdense homogenous enhancement MR t2 dark DDX: malignant lesions incl - sinonasal SCC - sinonasal adenoid cystic - adenocaricnoma - SNUC - lymphoma - melanoma - esthesioneuroblastoma
50
Granulomatosis with polyangitis is
also known as Wegeners, a multisysem necrotising non caseating granulomatous vasculitis affecting small to medium sized arteries/capilleries
51
Granulomatosis with polyangitis upper resp features
sinusitis/mastoiditis/otitis sclerosing oteitis of the nasal cavity sinonasal mucosal ulcers lacrimal gland involvement nasal septal perf/deviation subglottic stenosis
52
Sinonasal polyposis is
the presence of multiple benign polyps in the nasal cavity and paranasal sinuses
53
Sinonasal polyposis imaging and grading
extensive polyps occupying the nasal cavity and sinuses usually hypodense but can be hyper assoc local benign bone remodelling or erosion - mucoceles whole sinus expanded opacified ethmoid sinuses with convex lateral walls and air fluid levels concurrent infection can be present Meltzer 0 - no polyps 1 - single in middle meatus 2 - multiple in middle meatus 3 - extending beyond middle meatus 4 - nasal cavity obstruction
54
Antrochoanal polyps are
solitary sinonasal polyps that arise within the maxillary sinus. pass through the ostium to the nasapharynx and nasal cavity. can occur elsewhere less commonly. present with sinonasal obstruction
55
Antrochoanal polyp imaging
XR unilateral opac can see nasopharyngeal mass CT defined mass with mucin density widening of the maxially ostium extending to the nasopharynx no bony destruction, but smooth enlargement of the sinus can be dessicated and high density MR T1 intermediate to low T2 high homogenous C+ peripehral
56
Inverted papillomas are
type of Schneiderian papilloma representing an uncommon non cancerous sinonasal tumour most commonly seen in middle aged men. can undergo malignant transformation. classically have convoluted cerebriform on T2 and contrast imaging
57
Inverted papilloma imaging
CT non spec soft tissue density masswith enhancement location; most commonly lateral wall nasal cavity can have intralesional calc representing residual bone fragments MR distinctive convoluted cerebriform pattern on T2 and post con T1
58
Juvenile nasal angiofibroma is
a rare benign but locally aggressive vascular tumour of young men. vivdly enhancing soft tissue mass centred onthe sphenopalatine foramen. flow voids/s&p MR.
59
Juvenile nasal angiofibroma imaging
CT nasopharyngeal mass lobulated soft tissue mass cnetred on sphenopalatine fossa anterior bowing of the posterior maxillary wall marked enhancement Angio to see supply MR T1 intermediate T2 heterogenous, flow voids C+ prominent
60
Juvenile nasal angiofibroma staging
1a nasal cavity/nasopharynx 1b exension to sinus 2a into pterygomaxillary fossa 2b fills pterygomaxillary fossa bowing psterior wall max antrum anterior or into orbit 2c beyond pterygomax fossa into infratemporal fossa 3 intracranial exnteion
61
Tornwaldt cyst is
a common incidental benign nasopharyngeal mucosal cyst
62
Tornwaldt cyst imaging
well cricumscribed rounded immediately deep to mucosa bw/anterior to longus colli muscles ct low density non enhancing can be hyperattenuating mr t1 variable due to protein t2 high C+ no enhancement
63
Paranasal sinus mucocele is
complate opacification of a sinus by mucus, often with bony expansion due to obstruction. clinical presentation depending on direction of expansion and presence of infection
64
Paranasal sinus mucocele imaging
cant have air in the sinus CT complete opacification margins expanded and thinned may have bony resorption attenuation is variable MR signal intensity highly variable depdning on water/protein/mucus T1 low most common T2 high most common C+ if present than peripheral DWI variable
65
Sinonasal undifferentiated carcinoma is
a rare and highly aggressive neoplasm arising from the paranasal sinuses. Mostly ethmoid and superior nasal cavity.
66
Sinonasal undifferentiated carcinoma imaging
Ethmoid/superior nasal cavity Bone destruction CT: enhances to variable degree MR T1 iso to muslce T2 iso to hyper to muscle C+ heterogenous
67
Olfactory neuroblastoma/esthesioneuroblastoma is
a tumour arising from the basal layer of the olfactory epithelium in the superior recess of the nasal cavity. Usually presents as a soft tissue mass in the anterior/middle ethmoidal cells extending through the cribriform plate to the anterior cranial fossa.
68
Olfactory neuroblastoma/esthesioneuroblastoma imaging
Slow growing Begin at superior olfactory recess Involve ant/mid ethmoidal cells often form dumbell with waist at cribriform CT soft tissue can have focal calcs homogenous enhancement bone can be remodelled rather than destroyed MR T1 heterogenous T2 heterogenous C+ variable, usually bright Peritumural cysts at intracranial aspect
69
Olfactory neuroblastoma/esthesioneuroblastoma ddx
Olfactory neuroepithelioma Olfactory groove meningioma Sinonasal carcinoma - lack peritumoural cysts Rhabdo NPC - more posterior, older
70
Olfactory neuroblastoma/esthesioneuroblastoma stagign
Kadish a: nasal cavity b: nasal cavity and paranasal sinuses c: extends beyond - BOS - intracranial - orbit - mets
71
Sinonasal adenocarcinomas are
primary tumours of the sinonasal region with glandular differentiation. Classified into salivery and non salivery, NS into intestinal and non intestinal
72
Sinonasal adenocarcinoma imaging
Ill defined, heterogenously enhancing Intestinal tends to be ethmoid/nasal cavity Non intenstinal maxillary CT aggressive bone destruction heterogenous enhancement MR intermedialte T1 and T2 possible haemorrhagic foci heterogenous enahcnement
73
Paranasal sinus osteoma imaging
Location - mostly frontal - tehn ehtmoid, max - rare in sphenoid Can be ivory, mature or mixed Assoc with Gardners CT well circumscribed mass of variable density, ranging from v dense to more ground glassy MR low intensit all sequences ddx - FD - other osteogenic - osteoblastoma, osteosarcoma, cementoossifying fibroma
74
Encephalocoeles are
a form of neural tube defect where brain and meninges herniate through a cranial defect. can have a stalk in 15% to brainbut no fluid tract distinguishing from nasal encephaloceole mass, without pulsations or increased size with valsalva or compression of ipsilateral jugular vein
75
Sinonasal mucosal melanoma is
a rare subtype of melanoma. typically expansile mass centred within the nasal cavity, or less commonely, the paranasal sinuses.
76
Sinonasal mucosal melanoma imaging
CT polypoid or mass like bone remodelling or erosion strongly enhancing MR T1 homogenoeus,can be high T2 low C+ moderate enhancement
77
Sinonasal lymphoma is
involvment of hte nasal cav/paranasial sinuses with lymphoma. most commonly nasal cavity and maxillary sinus. generally t cell
78
Sinonasal lymohoma imaging
can be discrete or diffusely infiltrating CT soft tissue attenuating can have bone destruction MR T1 intermediate T2 hypointense C+ typically homogenous
79
Rhinoscleroma is
a chronic granulomatous infection involving the upper respiratory tract due to Klebsiella.
80
Rhinoscleroma imaging
Nasal mass with the following features CT bilateral or unilateral expansile homogenous hyperdense and non enhancing can extend through nares and into sinuses no bone destruction MR T1 mild to marked high signal T2 hyper with hypointense foci of fibrosis C+ inhomogenous DWI restriction with low ADC DDX Granulomatous disease Lymphoma and sinonasal carcinoma
81
Head and neck rhabdomyosarcoma general path
large proportion of all rhabdos and most common soft tissue sarcoma in the head and neck usually embryonal and in children can be orbital, parameningeal, middle ear or other
82
Head and neck rhabdomyosarcoma imaging
MR T1 iso to hyper T2 hyper C+ marked enhancement, usually heterogenous due to haemorrhage/necrosis Can have diffuse restriction
83
Le fort 1
horizontal maxillary fracture floating teeth passes through - alveolar ridge - lateral nose - inferior wall maxillary sinus - pterygoid plates
84
Le fort 2
pyramidal fracture, teeth at base and nasofrontal suture at apex floating maxilla fracture arch passes through - posterior alveolar ridge - lateral wall maxillary sinus - inferior orbital rim - nasal bone - pterygoid plate
85
Le fort 3
craniofacial disjunction floating face transverse line through - nasofrontal suture - maxillofrontal suture - orbital wall - zygomatic arch/zygomaticofrontal suture - pterygoid plates
86
Le fort practical points
Pterygoid plates Type 1 - anterolateral margin nasal fossa Type 2 - inferior orbital rim Type 3 - zygomatic arch Nasofrontal suture means type 2 or 3
87
Zygomaticomaxillary complex fractures comprise fractures of the
zygomatic arch inferior orbital rim, anterior/posterior maxillary sinus walls lateral orbital rim Imaging - fracture of the arch and/or temporozygomatic suture diastasis - fracture of the inferior orbitall rim, anterior and posterior maxillary sinus wall and/or zygomaticomaxillary suture - fracture of the lateral orbital rim and/or diastasis of the frontozygomatic suture
88
Nasoorbitoethmoid (NOE) complex fractures are
fractures involving the central upper midface. high impact to nose transmitted through ethmoid comminution of both medial maxillary buttresses results in a pattern of fractures involving the nasal bones, septum, ethmoid sinuses and medial orbital walls associated injuries - telecanthus - nasolacrimal duct - orbital injuries - CSF rhinorrhea - epiphora
89
Sialadenitis is, causes and associ
inflammation of the salivery glands causes - acute bacteria (staph and strep v) - stones - dehydration, immunosuppression, iatrogenic, cancer assoc - sjogren - mikulicz - post radiation - i-131 - HIV/IRIS
90
Sialadenitis imaging
US - enlarged - hypoechoic - hyperaemic - chronic; atrophic, hypoechoic, irregular margins CT - enlarged, abnormal attenuation, indistinct margin, contrast enhancement - stranding - silated duct - enlarged nodes - abscess MR - Acute T1 low, T2 high - Chronic T1 inhomgenous low, T2 low
91
Sialolithiasis location
almost always submandibvular wharton duct then parotid duct
92
Pleomorphic adenoma is
a benign mixed tumour, occuring most commonly in the salivery glands. most common SG tumour. well circumscribed mass commonly in the parotid,hypoechoic on us and t2 bright with homogeneous enhancement small risk of malig transformation to carcinoma ex pleomorphic adenoma
93
Pleomorphic adenoma location
80% parotid 10% SMG minor 6% sublingual 1% also commonly found in lacrimal gland
94
Pleomorphic adenoma imaging
rounded mass with bosselated or polylobulated borders commonly superficial lobe parotid can be deep lobe, extraparotid extendinfg to prestyloid parapahrynfeal space and stylomandibular tunnel US hypoechoic posterior acoustic enhancement CT homogeneous attenuation prominent enhancement larger can be heterogenous M T1 low T2 high+, decreased signal rim C+ homogenous enhancement
95
Pleomorphic adenoma ddx
When in parotid; - warthin - mucoepidermoid - myoepithelioma - adenoid cystic carc - mets - lymphoma - facial schwannoma
96
Warthin tumours are
benign tumours of the salivary glands most common from the parotid tail can be bilateral/multifocal second most common after pleomorphic
97
Warthin tumour imaging
commonly parotid tail at the mandibular angle sometimes elsewhere undergo cystic change more than any other salivary gland tumour US ovoid well defined multiple irregular spongelike areas larger; more cysts hypervasc CT well defined heterogenous solid cystic within the superficial parotid no calc moderate enhancement mural nodule common b/l MR well def and bilateral T1 low to intermediate, cysts have cholesterol and can be high T2 heterogenous and variable signal C+ solid parts enhance
98
Salivary gland tumours useful tips
benignity proportional to size - parotid commonly benign, SMG 50/50, minor mostly malig SUBTYPES Benign: epithelial - pleomorphic adenoma - warthin - intraductal papilloma - oncocytoma - myoepithelioma Benign: non epithelial - haemangioma - lymphangioma - lipoma Malignant - mucoepidermoid - Adenoid cystic carc - myoepithelioma - adenocarc - acinic cell carc - squamous - carcinoma ex pleomorphic adenoma - salivary duct carcinoma - metastases (cut SCC, melanoma, seminoa) - lymphoma
99
Mucoepidermoid carcinoma of salivary glands are
most common malignant primary of the parotid. also occur at hard palate commonly
100
Mucoepidermoid carcinoma of salivary glands imaging
US hypoechoic well circum CT well circum usually cystic components solid bits enhance calcs sometimes seen look like PMA higher grade; infiltrative MR low grade (like PMA) - T1 low to intermediate - T2 intermediate to high, cystic high - C+ heterogenous enhancement solid high grade - lower T2, poorly defined margins and infrequent cystic areas - assess for perineural spread
101
Adenoid cystic carcinomas are
second most common malig ofthe minor salivary glands behind mucoepidermoid locally aggressive with propensity for perineural spread
102
Adenoid cystic carcinoma imaging
Low grade; well defined High grade; infiltrative Frequently assoc with perineural spread MR T1 hypo to iso T2 hyper, higher grade more hypointense C+ homogeneous
103
HIV assoc salivary gland disease is
a condition of lymphatic infiltration of the salivary glands, particularly the parotids
104
HIV assoc salivary gland disease imaging
US numerous cysts/hypoechoic spaces without posterior enhancement straight up cysts for real CT/MRI bilateral salivary enlargement with intraglandular cystic and solid masses increased lymph nodes\ main jenny diffy would probably be sjogren they get multicystic appreance f the parotids, can be salivary glands
105
Supernumery teeth assoc
Cleidocranial dysostosis Gardner syndrome Cleft palate
106
Mesiodens is
a supernumery tooth in the palatal midline between the two maxillary central incisors
107
Mesiodens complications
impaction or delayed eruption central incisors widening of incisor gap abnormal poistion or curve of the incisors resorption incisors dentigerous cysts nasal cavity eruption
108
Periapical radiolucency ddx
Apical periodonitis (granuloma/abscess) Periapical cyst Cemento-osseous dysplasia Tumours Trauma Residual cyst
109
Periapical cysts are
also known as radicular cysts, most common cystic lesions. result from infection. generally small <1cm, round, pear shaped, thin rim of cortical bone usually restoration/cary of the adjacent tooth
110
Periapical granuloma is
a mass like region of granulation tissue in relation to teeth infection tend to be higher attenuating than periapical cysts
111
Periapical abscess is
acute infection of the periapical tissue around the root of the tooth
112
Periapical abscess imaging and complications
Imaging - well defined lucency - adjacent caries - adjacent empty socket Complications - OM - CNS infection - ludwig angina - deep space infection - sinusitis
113
TMJ dislocation typwa
abnormaly displacement with loss of normal articulation with the glenoid fossa can be - anterior - cranial - posterior anterior - most common - exaggerted and often recurrent normal anterior translocation of the condyule from the fossa cranial - rare, from upward force directing the condyle through the glenoid fossa into the middle cranial fossa posterior - rare
114
TMJ anatomy quick recap
synovial joint mandibular condyle and temporal mandibular fossa/glenoid fossa also anterior articulating eminence articular disc - anterior band, intermediate band, posterior band posterior band connects to bilaminar cartilage which connects to posterior capsule lateral pterygoid to anterior capsule
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TMJ normal appearance
disc is low signal all sequences, biconcave, located between the condyle and temporal bone with the posterior band at the 12 oclock position and the angle between the PB posterior limit and the vertical condyle <10deg can be anteriorly displaced in asx patients, only about 30% sx
116
TMJ dysfunction imaging
Direct signs - anterior disc displacement; displaced in closed mouth, can reduce when open (recapture) or not - posterior disc displacement; posterior band displcaed posteriorly beyond 1oclock - stuck disc; fails to displace in open or closed mouth position, fixed to temporal bone Indirect - large effusion - rupture of retrodiscal layers - thickening of the lateral pterygoid muscle attachment - OA changes
117
Mandibular osteoradionecrosis is
osteonecrosis following radiation therapy due to its superficial position. imaging - cortical destruction - sequestration - absence of a soft tissue mass
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Medication related osteonecrosis of the jaw is (drugs and imaging)
bony destruction of the jaw with exposed bone present for greater than 8 weeks in the presence of antiresorptive/antiangiogenic medication and absence of radiotherapy can get it with (OP, malig, immunosupp) - bisphosphanates - mabs - tyrosine kinase inhibs - VEGF inhibs - mTOR inhibs imaging - lucent or mixed lesion - sequestrum - periosteal prolif/rxn
119
Nasolabial cysts are
rare non odontogenic soft tissue developmental cysts occurring inferior to the nasal alar region
120
Nasolabial cyst imaging
simple cyst in the nasolabial region separated from bony structures and teeth
121
Incisive canal cysts are
developmental non neoplastic cysts arising from degenration of the nasopalatine ducts. develop in the midline anterior maxilla.
122
Dentigerous cysts are
slow growing, benign, non inflammatory odontogenic cysts. present as a well defined unilocular radiolucency surrounding the crown of an unerupted tooth within the mandible assoc with - mucopolysacc - basal cell naeuvys syndrome
123
Dentigerous cyst imaging
cystic expansile pericoronal lesion containing the crown of an impacted tooth tend toi attach to cementoenaml junction thin regular sclerotic margin variable size MR t1 low T2 high no enhancement
124
Stafne cyst is
a cortical defect near the angle of the mandible below the mandibular canal. can be filled by SMG or fat.
125
Temporomandibular joint inflammation causes
RA Ank spond CPPD Gout Psoriatic arthritis SLE JIA
126
Odontogenic keratocyst (OKC) are
rare, benign cystic lesions involving the mandible or maxilla. typically appear as expansile solitary unilocular lesion in the posterior mandible assoc - basal cell naecus (or Gorlin Goltz) - margans - noonan
127
Odontogenic keratocyst imaging
solitary radiolucent unilocular expansile smooth corticated borders typically posterior mandible large enough; resorp roots of tooth can sometimes be septated MR T1 high T2 heterogenous DWI restricts C+ peripheral enhancment no nodular component
128
Ameloblastoma is
a locally aggressive benign tumour arising from the mandible or sometimes maxilla
129
Ameloblastoma imaging
90% multicystic, soap bubble lesions well demarcated borders no matrix resorption of adjacent teeth can be unicystic and pericoronal, similar to dentigerous, OKC, ameloblastic fibromas MR mixed solid and cystic pattern thick irregular wall with enhancing papillary projections
130
Odontomas are
most common odontogenic tumours of themmandible assoc with gardner syndrome
131
Odontoma imaging
initially lucent, develops small calcs, eventually coalesce to form a radiodense lesion with a lucent rim
132
Aberrant internal carotid artery is
a variant of ICA that represents a collateral pathway resulting from involution of the normal cervical portion of the ICA enlargement of the small collaterals that pass lateral to the cochlear promotory - inferior tympanic aa (ECA) - caroticotympanic aa (petrous ICA) vessels rejoin the petrous segment. May present with pulsatile tinnitus
133
Aberrant ICA imaging and ddx
enlarged inferior tympanic canaliculus retrotympanic mass absent carotid plate absent or hypoplastic vertical segment of the carotid canal ddx - lateralised ICA: protrudes into the anterior mesotympanum but dosnt course across the cochlear promotory or enlarge the inferior tympanic canaliculus - petrous ICA aneurysm - glomus tympanicum - glomus jugulare - dehiscent jugular bulb
134
Temporal bone fracture breakdown and complications
Fracture orientation - longitudinal - horizontal - mixed Otic capsule involvement, predicts; - faical nerve involvement -CSF leak - sensorineural hearing loss - epidural/SA haematoma Complications - facial nerve palsy - ossicular chain disruption - otic capsule involvement - CSG leak - meningitis - post traumatic cholesteatoma - perilymphatic fistula
135
Acute otomastoiditis imaging
CT - opacification - erosion of septa - erosion of lateral wall or sigmoid plate - soft tissue abscess - petrous apicitis - cerebral abscess or dural venous sinus thrombosis MR - opacification T1 low T2 high DWI possible C+ mucosal enhancement typical
136
Bezold abscess is
complication of otomastoiditis deep to scm
137
Citelli abscess is
complication of otomastoiditis abscess in digastric triangle (or OM of occipital bone, same name)
138
Acute otomastoiditis complications
subperiosteal abscess bezold abscess citelli abscess labyrinthitis petyrous apicitis intracranial extension facial nerve dysfunction thrombosis of mastoid emissary vein (griesinger sign)
139
Petrous apicitis clinical presentation
Otomastoiditis symptoms and - deep facial pain due to meckels cave inflammation - abducens nerve palsy (gradenigo syndrome) inflammation of dorellos canal
140
Cholesteatoma general types
Congenital Acquired - priamry (no hx of infection) - secondary - pars flaccida - pars tensa External ear canal Mural cholesteatoma Petrous apex
141
Cholesteatoma important features to report
Erosions - scutum, ossicles, lateral semicircular Dehiscence - facial nerve canal, tegment tympani Integrity of - epitympanum, aditus ad antrum, oval and round window Presence in sinus tympani
142
Sinus tympani is
small recess in posterior mesotympanum medial to pyramidal eminence and stapedius muscle origin
143
Congenital cholesteatoma imaging
Characteristically in the petrous apex MR T1 low T2 high FLAIR can have partial attenuation (unlike cholesterol granuloma) C+ non enhancing, or maybe margins DWI restricted diffusion
144
Acquired cholesteatoma path and complications
typically middle ear, result from chronic infection four hypothesis - invagination/negative pressure, eustachian tube dysfx and membrane retraction - invasion migration - basal cell hyperplasia - metaplasia complications - labyrinthine fistula - cochlear fistula - labyrinthitis - facial nerve dysfx - extension through IAM, middle cranial fossa, petrous apex
145
Acquired cholesteatoma imaging
Depends on part of the TM it arises from; Pars flaccida - superior extension; expands into prussak space, eroding the scutum, displacing the ossicles medially - inferior extension; less common Pars tensa - posterosuperior; extends medial to the incus and displaces the ossicles laterally - anteiror and inferior MR T1 low T2 high C+ none DWI restricts
146
Acquired cholesteatoma ddx
Cholesterol granuloma - high t1 - no enhancement - no restriction Mucoid impaction Glomus tympanicum Facial nerve schwannoma Post op: Recurrence - low t1 Granulation tissue - intermediate t1 - enhancement - low DWI Scarring - low T1/T2 - low DWI
147
External auditory canal atresia imaging and associations
Assoc - crouzon - treacher collins - goldenhar - pierre robin CT mention - middle ear cavity volume - ossicles (often involved) - inner ear structure, both windows need to be there - course of the ICA and jugular bulb - course of the facial nerve
148
Dehiscent jugular bulb is
absent sigmoid plate with a high riding jugular bulb. cause of pulsatile tinnitus and retrotympanic vascular mass.
149
Semicircular canal dehiscence clinical
Superior - vestibular and visual symptoms - tullio phenomenom - vertigo and nystagmus from loud noises - auditory dysfunciton Posterior - mostly hearing
150
Large endolymphatic duct and sac syndrome imaging and associations
Assoc - pendred syndrome - vestibular anomalies - cochlear anomalies - semicircular canal anomalies Imaging - enlarged vestibular aqueduct >1.5mm at the midpoint (valvassori) - opercular width >2mm (Cincinnati)
151
Petrous apex mucocele iamging
CT smooth expansile lesion MR T1 low to intermediate T2 high C+ no central, can have peripehral DWI no restriction DDX Cholesterol granuloma - should be high on T1
152
Labyrinthitis ossificans is
ossification of the membranous labyrinth as a response to insult, commonly infection but also surgery or trauma, autoimmune or sickle cell
153
Labyrinthitis ossificans imaging
Scala tympani of the basal turn of the cochlea is the most commonly affected site CT - mild: hazy increased density in the fluid spaces - moderate: focal areas of bony encroachments - severe: complete obliteration MR loss of normal high fluid signal
154
Otosclerosis is
a primary osteodystrophy of the otic capsule. Can have conductive, sensorineural or mixed hearing loss. Commonly bilateral. Two phases - otospongiosis and otosclerosis Two subtypes - fenesteral and retrofenestral Fenestral (stapedial) - involves the oval window and stapes footplate - hearing loss is conductive due to fixation Retrofenestral (cochlear) - cochlear involvement and demineralisation of the cochlear capsule - hearing loss is sensorineural
155
Otosclerosis imaging
Fenestral - just anterior to the oval window - fissula ante fenestram - bony overgrowth can cause fixation of the stapes Retrofenestral - second most common - invovlement of the round window niche - bone surrounding cochlea, can be focal or circumfrential Otospongiotic phase - demineralisation and spongy bone cause lucency Otosclerotic - region increases in attenuation DDX - OI - Pagets - osteoradionecrosis
156
Otosclerosis grading
Symons and fanning Grade 1 - solely fenestral Grade 2 - patchy localised cochlear disease a) basal cochlear turn b) middle/apical turns c) both basal and middle/apical turns Grade 3 - diffuse confluent cochlear invovlement of the otic capsule
157
Cholesterol granuloma is
sometimes called a choclate cyst of the ear or blue domed cyst special type of middle ear granulation tissue which is particularly prone to bleeding and frequent cause of haemotympancum most common cystic lesion of the petrous apex
158
Choleterol granuloma imaging
CT - expansile well marginated lesion with thinned overlying bone - can look more aggressive/erosive at the petrous apex, less so in the middle ear MR T1 - high due to cholesterol component and methaemoglobin +/- haemosiderin rim T2 - central high signal - peripheral low signal rim FLAIR - no attenuation C+ can hve faint peripheral enhancement DWI - no restriction
159
Cholesterol granuloma ddx
Asymmetric marrow/pneumatisation Middle ear effusion Cholesteatoma Base of skull tumours Hydrated mucocele - can be identical Thrombosed ICA aneurysm - usually more complex - can have a residual flow signal
160
Cochlear implant assessment
Modified stenvers view - positions it in the plane of the sueprior semicircular canal - cochleostomy in vertical plane with superior semicircular canal - electrodes should be medial to stomy
161
Inner ear malformations classification
Sennaroglu 1. Complete labyrinthe aplasia (Michels) 1 ) with hypoplastic petrous b) without otic capsule c) with otic capsule 2. Rudimentary otocyst - round or ovoid cystic space in place of the inner ear - IAC absent - carotid canal absent - SCC may be present rudimentarily 3. Cochlear aplasia a) normal vestibule b) dilated vestibule 4. Common cavity - absent normal diff between cochlea and vestibule 5. Cochlear hypoplasia a) bud like b) cystic hypoplastic c) cochlea with less than 2 turns d) cochlea with hypoplastic middle and apical turns 6. Incomplete paritition of the cochlea - defects involving the modiolus and interscalar septa a) type 1 cystic cohleovestibular anomaly b) type 2 part of mondini (if enlarged vestibular aqueduct) c) type 3 X linked deafness 7. enlarged vestibular aqueduct 8. Cochlear aperture abnormalities
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Persistent stapedial artery is
an abnormal small vessel arising form the petrous portion of the intenral carotid artery and crossing through the middle ear results from failure of regressin of the embryonic stapedial artery imaging - small canaliculus originating from the petrous segment of the ICA - linear segment of soft tissue density corssing over the cochlear promontory - enlarged facial nerve canal or separate canal - aplastic or hypoplastic foramen spinosum
163
Necrotising otitis externa is
severe invasive infection of the EAC which can raidly spread. typically diabetics, immunosuppressed, elderly pseudomonas 98%
164
Intralabyrinthine haemorrhage
this is a thing intrinsic high t1 from methaemoglobin
165
Ramsay hunt syndrome is and imaging
shingles of the facial nerve, reactiation of VZV otalgia, facial nerve palsy, vesicular eruption invovling the tongue, pinna, EAC identical to Bells with increased enhancement of the facial nerve
166
Normal facial nerve enhancement
typical sites - fundal canalicular - anterior gen - posterior genu rarely other places but shouldnt have it in the meatal segment or extracranial
167
Endolymphatic sac tumours are and imaging
locally invasive tumours of the endolymphatic sac/duct. assoc with von hippel lindau almost always arise from the vestibular aqueduct involving the sac or duct CT infiltrative or moth eaten erosion central calcific spiculation and posterior rim calcification intense enhancement MR T1 foci of hyper C+ heterogenous T2 heterogenous
168
Keratosis obturns is and imaging
rare EAC disease characterised by expansion of the EAC by a plug of desquamated keratin CT well defined soft tissue mass within the EAC diffusely enlarged without erosion
169
Branchial cleft anomalies
comprise a spectrum of congenital defects that occur in the head and neck result from persistence of branchial cleft or pouch resulting in a cevical anomaly located along the anterior border of the sternocleidomastoid muscle from the tragus of the ear to the clavicle encompass cysts, fistulas and sinuses
170
Types/locations of branchial cleft anomalies
First - above the level of the mandible near the EAC within or close to the parotid gland Second - between the mandible angle and the carotid bifurcation - deeper than the platysma and superficial layer of deep cervical fascia - between pharyngeal wall to skin, laterally and inferiorly between ICA and ECA - extension between the ICA and ECA above bifurcation "notch/tail/beak sign" - most common 95%, most common of these is at the angle of the mandible Third - infrahyoid neck - posterior to the common or internal carotid, between the hypoglossal nerve below and glossopharyngeal nerve above - most lie in the posterior cervical space posterior to the sternocleidomastoid - if a sinus can drain to pyriform sinus Fourth - infrahyoid neck usually adjacent to the thyroid gland - can be hard to tell from a third - parallel the course of the recurrent laryngeal nerve - more common on the left - usually form a sinus with apex at the pyriform sinus, like the third, but extend inferiorly to reach anterior left upper thyroid lobe
171
Thyroglossal duct cyst is and imaging
congenital neck cyst/mass typically midline, can be anywhere from foramen caecum to thyroid gland, though typically infrahyoid minimally complex on US unless infection may have slight rim enhancement can rarely have a papillary carcinoma assoc generally within 2cm of midline usually deep to strap muscles, can be embedded MR T1 variable T2 typically high C+ none if uncomplicated
172
Oesophageal diverticula classification
can be false or true - true: all layers - false: herniating through muscle layer Can be traction or pulsion - traction: secondary to pulling forces on outer oesophagus - pulsion: occurs secondary to increased intraluminal pressure Can be upper, middle or lower Upper - Zenkers - Killian Jamieson Middle - traction diverticula (2nd to fibrosis/inflammation/scarring) - pulsion: secondary to pressure Lower - epiphrenic
173
Zenkers diverticulum is
a posterior outpouching of the hypopharynx just proximal to the upper oesophageal sphincter through a weakness in the muscle layer called Killian dehiscence/killian triangle
174
Killiam Jameison diverticulum is
false diverticulum of the upper oesophagus through the killian jameison sapce. just below circopharyngeus, anteriorly and laterally
175
Epiphrenic diverticulum are
pulsion diverticula of the lower oesophagus just above the lower oesophageal sphincter more frequently at the right posterolateral wall
176
Thymic cysts are
cysts that occur within or arise from the thymus can be acquired on congenital congenital - arise from a patent thymopharyngeal duct - contain thymic tyissue - often unilocular - can be cervical aquired - secondary to thoracotomy or following treatment - assoc with thymic tumours - cann be uni or multilocular can be cervical or mediastinal
177
Carotidynia is
also known as fay syndrome, characterised by neck pain in the region of the carotid bifurcation aetiology is unclear. elevated inflammatory markjers. typically about the bifurcation mild narrowing of the lumen eccentric wall thickening, enhancement, fat stranding king kong carotid ddx dissection vasculitidies
178
trigeminal nerve denervation
muscles of mastication mylohyoid anterior digastric tensor tympani/tensor palatini
179
hypoglossal nerve denervation
unilateral tongue atrophy, except for palatoglossus (X)
180
Castleman disease is
an uncommon benign b cell lymphoproliferative condition can be unicentric or multicentric (usually HIV)
181
Kimura disease is
a rare benign inflammatory disease manifestly as enlargement of the cervical nodes and salivary glands
182
high attenuating nodes
intrinsic - granulomatous infection - sarcoid - amyloid - castleman - treated lymphoma - occupational lung diseases - rosai dorgman - papillary, bronchogenic, breast, mucinous, osteosarc hypervascular - kaposis - papillary thyroid, NET, RCC - castleman - kimura - kikuchi fujimoto - angioblastic t cell lymphoma
183
mycosis fungoides is
a type of malignant cutaenous primary t cell lymphoma
184
Thyroglossal duct cyst imaging
Anywhere from foramen caecum to thyroid gland typically infrahyoid and within 2cm of midline US usually simple can be complex assoc soft tissue lesion ?papillary ca vs ectpic thyroid CT usually simple rim enhancement can be embedded in the strap muscles MR T1 variable T2 high C+ rim can be
185
Lingual thyroid imaging and ddx
us absent thyroid ct hyperdense soft tissue mass homogenous enhancement MR well defined T1 iso to hyper T2 varibale C+ strong NM tech or iodine scan DDX lingual tonsil thyroglossal duct cyst malignany hamengioma dermoid
186
Hyperthyroidism causes
Increased stim - hcg secretion - excess TSH secretion - TSH receptor stim ab; graves independant function - functioning adenoma, multinodular goiture Inflammation - autoimmune (hashimotos, post partum) - post viral (de quervins) - infections - iatrogenic Extrathyroid - dietary - neoplasic (mets, pit adenoma, struma ovarii) Iodine exposuire
187
Hypothyroidism causes
Primary - autimmune - iodine deficiency - thyroiditis (post partum, subacute, riedel, silent) - post radiation - infiltrative (lymphoma, sarcoid, amyloid, tb) Secondary - pit adenoma - pan hypopit - post radiation - infiltrative Congenital - absent thyroid - ectopic/underdeveloped - dyshormonogenesis drug induced
188
Graves disease is
an autoimmune thyroid disease and most common cuase of thyrotoxicosis caused by ab directed stimulation of the TSH receptor with increased prod and release to t3 and t4
189
Graves disease imaging
US enlarged hyperechoic heterogenous absence of nodularity hypervascular (thyroid inferno) NM I123 homogeneously increased uptake T99m homogeneously increased uptake pyraimydal lobe Thyroid dermopathy/acropachy Graves ophthalmopathy exophthalmos/palps/goitre = merseburger triad
190
Thyroid acropachy imaging
almost always assoc with ophthalmopathy xr symm hands and feet invovlement tubular bones prominent smooth flowing periosteal reaction soft tissue swelling
191
Graves orbitopathy imaging
enlarged muscles sparing of the musculotendinous junction coke bottle LPS - IR - MR - SR - LR - Obliques exophthalmos - 1cm to posterior sclera - 2cm to anterior globe - interzygomatic line
192
Graves orbitopathy ddx
pseudotumour sarcoid lymphoma mets amyloid erdheim chester
193
Hashimotos thyroiditis is
a subtype of autoimmune thyroiditis usually presents with hypo and a goitre can present with hyper anti tg antibodies, tpo
194
Hashimotos imaging
enlarged thyroid, can be atrophic later heterogenous hypoechoic micronodules with surrounding echogenic septations (pseudonodular/giraffe) usually normal or decreased flow but can be hypervasc prominent reactive cervical nodes NM early increased late spots of reduced uptake
195
Thyroid lymphoma is/imaging
rare. usually non hodgkins. assoc with hashimotos. imaging similar to primary thyroid malignancies and hashimotos US nodular diffuse mixed calcs are uncommon CT goitre hypoattenuating hterogenous enahncement MR t1/t2 iso to hyper
196
Goitre causes
non toxic simple graves mng hashimotos thyroid cancer drugs/diet depositional eg amyloid misc; plummer vinson
197
Riedels thyroiditis is/imaging
a rare form of autoimmune thyroiditis, sometimes considerted a manifestation of igG4 disease stony or woody assoc - retroperitoneal fibrosis - sclerosing fibrosis - orbital pseudotumour - fibrosing mediastinitis imaging US - homogenously hypoechoic with poor demarcation fo the gland borders CT compression of lcoal structures by an enlarged thyroid with low attenuation change areas within MR low on T1 and t2
198
De quervains thyroiditis is/imaging
a form of self limiting subacute thyroiditis usually preceded by an upper respiratory tract infection hyper followed by hypo symptoms followed by euthyroid US poorly defined regions of decreased echos decreased vasc in areas NM low uptake in a patient with hyperthyroidism
199
Follicular adenoma imaging
thin peripheral halo predominantly cystic or mixed isoechoic or anechoic homogenous or hetero absence of internal flow
200
Papillary thyroid cancer imaging
US solitary mass irregular outline small punctate microcalcifications nodes can cavitate, have septa, mural nodules CT nodes have - cystic components - thick nodular walls - septa - sometimes calc - sometimes purely cystic MR can have cystic bits solid bits enhance variable t2 NM concentrates radioiodine but not pertechnetate FDG avid
201
Follicular thyroid carcinoma imaging
typically hypoechoic lacks cystic change concentrates pertechnetate but not radioiodine
202
Medullary thyroid carcinoma imaging
sporadic or familial - MEN 2a/b - VHL - NF1 US - punctate foci of calc in primary and nodes CT irregular dense calcific foci NM do not concentrate radioiodine FDG avid mets concentrates thallium
203
Anaplastic thyroid carcinoma imaging
US microcalc usually infiltrative CT nodes infiltrative primary NM no radioiodine uptake
204
Hyperparathyroidism assoc and subtypes
Assoc: - MEN 1 - MEN 2a - familial hypocalciuric hypercalcaemia - familial isolated primary hyperparathyroidism - hyperparathyroidism jaw tumour syndrome Primary - parathyroid adenoma - parathyroid hyperplasia - parathyroid cacinoma - parathyromatosis Secondary - caused by chronic hypocalc with renal osteodystrophy (or malnurtriton, or vit d def) - results in parathyroid hyperplasia Tertiary - autonomous parathyroid adenoma caused by chronic overstimualtion of hyperplasitc gflands in renal insufficicency
205
Hyperparathyroidism imaging
Subperiosteal bone resorption - radial middle phalanges - medial long bones - lamina dura Subchondral resorption - clavs, PS, SIJ Subligamentous resoprtion - ischial tube - trochanters - inferior calcaneus and calvicle Intracortical resorption Terminal tuft erosion Rugger jersey Osteopaenia Brown tumours Salt and pepper skull Chondrocalcinosis Renal osteodystrophy/osteomalacia vit d - osteopaenia - subperiosteal resorption - rugger jersey spine - soft tissue calc - superscan - rib notching
206
Parathyroid adenoma imaging
Typically juxtathyroidal Ectopic - mediastinum - retropharyngeal - carotid sheath - intrathyroidal US - homogenously hyopechoic - echogenic capsule - can show a feeding vessel on doppler Tc99m sestamibi uptake CT intense arterial enchancement washout on delayed low attenuation on nc polar vessel sign variable MR findings
207
Parathyroid hyperplasia aetiology
Primary - sporadic - familial MEN 1 and 2a Secondary - renal failure tv99m mibi
208
Parathyroid carcinoma imaging
invasiveness calcifications heterogeneity lobulated morph larger negative predictors - absence of suspicious vascularity - absent thick capsule - homogenity of capsule
209
Hypoparathyroidism causes
iatrogenic congenital absence familial idiopathic pseudo - abnormal end organ resistance pseudopseudo - similar to pseudo without alterations in pth levels and calc metabolism
210
Hypoparathyroidism imaging
MSK - focal and generalised osteosclerosis - dense metaphyseal bands - skull vault thickening - subcut calc - DISH CNS - intracranial calc - cataracts
211
Pseudohypoparathyroidism imaging
MSK - short stature - brachydactyly - soft tissue calc - exostoses - broad bones with coned epiphyses CNS - BG calc - sclerochoroidal calc - deep white matter calc
212
MEN 1
pituitary adenoma islet cell tumours of the pancreas parathyroid proliferative diseases PiParPanc
213
MEN 2a
Phaeochromocytoma Medullary thyroid cancer Parathyroid hyperplasia PMP
214
MEN 2b
phaeochromocytoma medullary thyroid marfanoid mucosal neuroma/ganglioneuroma PMMM
215
Orbital dermoid imaging
deep (within orbit) or superifical (adjacent to orbital rim) most commonly upper outer quadrant usually extraconal, non enhancing smooth margins cystic/solid components heterogenous with internal fat
216
Orbital epidermoid is
a rare cause of an orbital mass can be congenital or acquired most commonly affect the eyelid but can be truly intraorbital
217
Retinal detachment types and aetiology
Rhegmatogenous Non rhegmatogenous - retinal break - lattice degeneration - tractional - exudative Rhegmatogenous - posterior vitreous detachment - trauma Tractional - Diabetic retinopathy - sickle cell retinopathy - retinopathy of prematurity Exudative - central serous chorioretinopathy - vogt koyanagi harada disease - coats disease - choroidal neoplasms
218
Retinal detachment imaging
US - bright continuous and folded membrane within the vitreous - freely moving/aftermovement - less mobile than posterior vitreous detachment CT - folded membranes within subretinal space - limited anteriorly by the ora serrata - posteriorly converges on the optic disc
219
Choroidal detachment aetiology
trauma surgery spontaneous medications for lower iop hypertension neoplastic inflammatory choroidal disordrs caroticocavernous fistula severe atherosclerosis