Radiodx Flashcards

1
Q

Weightlifter on steroids, has scleral icterus and hyperechoic liver, Dx

Fatty liver

Cirrhosis

Steatohepatitis

A

Steatohepatitis

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2
Q

Male, obese, breast lump that is lucent with a thin rim, ultrasound is intensely hyperechoic

Gynaecomastitia

Pseudogynaecomastitia

Lipoma

Breast cancer

A

Lipoma – typically iso but can be hyper

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3
Q

Beta decay is

Nucleus has too many neutrons
Nucleus has too many protons
Shell has too many electrons
Emits gamma radiation
Emits X-rays

A

Nucleus has too many neutrons

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4
Q

Regarding technetium :

Half life of 8 hours is useful

Decay product Mo99 does not confer additional radiation to the patient

Produces energies 50-5000keV

Energy produced is high enough to pass through patient tissue

Produces beta and gamma rays

A

Energy produced is high enough to pass through patient tissue

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5
Q

ARPKD associations:

Caroli

Congenital hepatitic fibrosis

Von Meyenburg complexes 

A

Congenital hepatitic fibrosis - the best one

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6
Q

VQ :

1 or more filling defects is high risk on PIOPED

Low risk excludes PE

Over 90% of changes resolve over 12 months

Unilateral loss of perfusion is more likely due to bronchial obstructing tumour than massive PE

A

Unilateral loss of perfusion is more likely due to bronchial obstructing tumour than massive PE

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7
Q

Some dude has CNS symptoms, MRI shows mixed signal cystic structures in bilateral thalami, some rim enhancing, basal meningeal enhancement

TB -

Cryptococcosis

HSV

Toxoplasmosis

A

Answe: Cryptococcosis

TB - probably not, because T2 dark

 Racemose neurocysticercosis: cystic grape like structures in the basal cisterns

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8
Q

25 yo male tourist visiting friends, 2 days cough, fine subtle reticular opacities, right mid zone thin walled cyst, dx most likely

Mycoplasma

TB

PCP

Streptococcus?

A

Mycoplasma - pneumotocele can occur, walking pneumonia

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9
Q

 37 yo woman undergoing IVF with multiple cystic lesions left adnexa, right ovary normal

Normal response

Hyperstimulation

PCOS

Tuboovarian abscess

Cystadenoma

A

Cystadenoma

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10
Q

Which rules determine ankle imaging in acute staging

Nexus

Ottowa

Montreal

Wisconsin

Gabes Lau

A

Ottowa

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11
Q

67 yo man in MVA haemodynamically stable but with chest pain. CTA chest shows 2 mm smooth outpouching just beyond the left subclavian artery:

Aortic pseudoaneurysm

Ductus diverticulum

Traumatic dissection

Others?

A

Ductus diverticulum

Ductus diverticulum: a developmental outpouching of the thoracic aorta, at the anteromedial aspect of the aorta - at the site of the aortic isthmus, where the ligamentum arteriosum attaches

The differential is an aortic pseudoaneurysm, which forms sharp margins with the aorta, the ductus diverticulum usually appears as a smooth focal bulge with gentle obtuse angles with the aortic wall

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12
Q

Young guy twisting injury with proximal fibulae fracture and lateral talar shift

Weber A

Weber B

Weber C

Maisonneuve

Tillaux

A

Answer:Maisonneuve: combination of a fracture of the proximal fibula with an unstable ankle injury = ligamentous injury and/or fracture of the medial malleolus

Tillaux: Salter Harris III fracture through the anterolateral aspect of the distal tibial epiphysis with variable displacement

  • The anterior tibiofibular ligament avulses the anterolateral corner
  • vertical fracture through the distal tibial epiphysis, with horizontal extension through the lateral aspect of the physis
  • Differential is a triplanar fracture, which will have a metaphyseal fracture in coronal
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13
Q

Young man MVA with fracture anterior and posterolateral maxillary sinus, zygomaticofrontal region, zygomaticotemporal, zygomatic arch

Tripod

Lefort 1

Lefort 2

Lefort 3

Nasoethmoidal fracture

A

Tripod - does not mention pterygoid, otherwise would be Lefort3

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14
Q

Most likely to cause cyanosis :

PDA
VSD
ASD
Transposition of the great arteries
Patent foramen ovale

A

Transposition of the great arteries

Cyanotic CHD: the 5Ts
TAPVR
Transposition of the great arteries
Truncus arteriosus
Tetralogy of Fallot
Tricuspid valve abnormalities and hypoplastic right heart syndrome
Ebstein anomaly

Acyanotic CHD:
VSD
ASD
AVSD
PDA
Coarctation
Pulmonary stenosis

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15
Q

Renal transplant :

High RI is specific for rejection

Reversed diastolic flow indicates venous thrombosis

Lymphoceles accumulate radiotracer

Lymphoceles develop in the first few days

A

Answer: Reversed diastolic flow indicates venous thrombosis – true but not specific

High RI is not specific

A lymphocele may occur from 2 weeks to 6 months after transplantation with a peak incidence at 6 weeks

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16
Q

FSE TSE question which limits scan speed

TE
TR
TI
SAR

A

Answer: TR – echo train length

SAR – this depends on the strength of the magnet

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17
Q

40 yo with sacral destructive lesion with rings and arcs:

Chordoma
GCT
Chondrosarcoma 

A

Answer: Chondrosarcoma 

Chordoma common but no rings and arcs

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18
Q

Long stem about DOPS and shoulder ultrasound, which is best position to have arm for infraspinatus tendon

Internal rotation arm touching opposite shoulder

External rotation arm behind back

Abducted arm

A

Internal rotation arm touching opposite shoulder

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19
Q

Woman from med onc outpatients with RIF pain, enterocolitis with trilaminar appearance and middle layer 35 HU, most likely

Typhlitis
Crohn disease
Ischaemic
Radiation

A

Typhlitis

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20
Q

Patient brought to department for investigation over liver lesion. Patient says he’s in hospital for hernia repair and has no liver lesion. On checking it is the correct patient who’s been brought down

Wrong sticker on form
Patient is lying
Trolley bay mix up
CA has brought wrong patient
CT techs got it wrong

A

Wrong sticker on form

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21
Q

5 yo child with bilateral perihilar streaky opacities, pneumonia, organism

Mycoplasma
Streptococcus
Staphylococcus

A

Mycoplasma

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22
Q

Down screening which is used in 1st trim

Nasal bone length
Alpha fetoprotein
Twin vs singleton
Parity

A

Alpha fetoprotein – second trimester, none of the other make sense

1ST TRIMESTER: Combined serum screening
Performed at 9-12 weeks
Better detection rate the earlier its performed
Measures free B-HCG and PAPP-A

2nd TRIMESTER: Maternal serum screening
Performed at 14-20wks, ideally 15-17
Measures Alpha fetoprotein (AFP), free B-HCG, unconjugated oestriol +/- inhibin A

1ST TRIMESTER
Nuchal translucency
The fluid-filled subcutaneous space at the back of the fetal neck
Different to the nuchal fold = seen in the second trimester
Thickening is thought to relate to dilated lymphatic channels, a non-specific sign of generalised abnormality

Associations:
Aneuploidy :
Trisomies
Turner

Non-aneuploidy:
Congenital heart disease
Noonan syndrome
Congenital diaphragmatic hernia
Omphalocele
Skeletal dysplasia
VACTERYL

Miscarriage/fetal demise

Intrauterine infection - Parvovirus B19

<3mm is normal
3.4mm = risk of 7%, >8,5mm has a risk >75%

Correlate with serum markers
Further workup with amniocentesis and or chorionic villus sampling, as well as fetal echo

Technique:
Mid-sagittal plane, nasal bone, tip of nose, hard palate and diencephalon must be seen
Calipers are placed inside the hyperechoic edges

2nd TRIMESTER
Chorionic villus sampling: 11-12 wks
Amniocentesis: 15-18 wks

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23
Q

Foetal hydrops, chest lesion, stomach bubble normal place, see a vessel from below diaphragm in lesion

Sequestration
Congenital diaphragmatic hernia
Congenital adenomatoid malformation 

A

Sequestration

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24
Q

Gastroschisis which is true :

Small defect 2-4 cm
Liver herniated 40-50%
Associated with chromosomal abnormalities
Covered by membrane

A

Small defect 2-4 cm - tends to be about 4cm, rare to have liver – should never have liver

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25
Q

30 year old male with a lump in soft tissues high signal on T1 weighted imaging without fat suppression

Lipoma

Liposarcoma

Haemangioma 

A

Lipoma - High T1, if no fat sat…if says High T1 post FS, then think liposarcoma.

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26
Q

Long winded question about comparing US vs MRI for assessing haemangioma of liver, if TP=a, FP=b, TN=c, FN=d, how to calculate prevalence in their study population (I’m only sure on the last opDon, not sure if the other 4 are accurate)

a/b+d

a/a+c

b/a+c

b/c+d

a+d/a+b+c+d

A

a+d/a+b+c+d - prevalence is the number of cases / everyone in the population

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27
Q

True about PCP

Affects upper lobes more than lower

Commonly associated with pleural effusion

Often coexists with CMV

A

Often coexists with CMV - Cytomegalovirus (CMV) pneumonia is a complication presented by these patients when they are in a state of severe immunosuppression. 

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28
Q

Patient during angiogram feels unwell with HR 50, BP 80/50

IV atropine 0.6 mL (dose?)
IM adrenaline 0.5 mL
IV adrenaline 1 mL (dose?)
Hydrocortisone?
Antihistamine?

A

IV atropine 0.6 mL (dose?)

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29
Q

Anaphylactic reaction 3 minutes after scan

IM adrenaline
IV adrenaline
Hydrocortisone
Antihistamine
Pretend you didn’t hear the code (I made this one up)

A

IM adrenaline

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30
Q

You find 1 cm nodule on routine preoperative X-ray in patient awaiting suspicious for cancer, what do you do (something about according to college guidelines)

Call referrer
Make sure secretary faxes report to GP
Fax report to GP and cardiothoracic surgeon
Tell referrer to read your report
Close the study and let someone else sort it out (I made this one up)

A

Call referrer

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31
Q

Most often proposed mechanism for NSF :

Free gadolinium gets into tissues and incites fibrotic response
Free Gd chelate gets into soft issues
Albumin bound Gd gets into issues
Some other combinations of chelated and otherwise bound Gd

A

Free gadolinium gets into tissues and incites fibrotic response

Nephrogenic systemic fibrosis

Occurs almost exclusively in patients with renal impairment + gad based contrast agents

May be due to transmetallation - the replacement of the gadolinium from the chelate and forming a free gadolinium ion, free gadolinium ions may then deposit in different tissues and result in inflammation and fibrosis

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32
Q

50 yo non smoker with 7 mm nodule

Do nothing

Follow up in 12 months and stop if unchanged

Follow up in 3-6, 9-12 and 24 months

Follow up in 6-12 months, then 18-24 months if no change

Further work up with other imaging

A

Follow up in 6-12 months, then 18-24 months if no change

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33
Q

Post menopause woman with 7.6 cm simple ovarian cyst

Refer to gynaecologist
Follow up in 6 weeks
Ultrasound guided aspiration
Do nothing
Follow up in 1 year?

A

Follow up in 1 year?

Post menopausal
3 - 5cm, F/U in 3-6mo for resolution
>5cm: F/U in 3 - 6mo for resolution/recharacterise or in 6-12 mo for growth assessment

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34
Q

Young woman 2.4 cm cystic ovarian lesion

Do nothing this is normal
Follow up in 1 year
Follow up in 6 weeks
Aspiration

A

Do nothing this is normal

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35
Q

Tubular breast cancer

Typically has 5 y survival of 70%

Is associated with further lesion in same or other breast in <5%

Can be essentially unchanged over several years

A

Can be essentially unchanged over several years

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36
Q

Most likely spiculated lesion

Fibroadenoma
Papillary neoplasm
Mucinous
Medullary
Tubular

A

Tubular

Spiculated lesion :
Sclerosing adenosis
Post surgical scar
Radial scar
Fat necrosis
IDC, DCIS
ILC
Tubular carcinoma

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37
Q

Bilateral renal ostial stenosis

Takayasu
PAN
FMD
NF-1

A

NF-1 - Renal artery stenosis in NF1 is usually ostial in location,

The most common vascular abnormality in patients with NF1 is bilateral or unilateral renal artery stenosis

FMD in comparison: 95% of all stenoses are found in the distal 2/3rds of the renal artery, more than 50% of all NF1 stenoses are located in the ostia

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38
Q

Renal nuclear medicine scans

DTPA has 100% glomerular filtration
MAG3 good for pseudotumour
MAG3 good for calculating GFR
Renal scan has blood pool, parenchymal and excretory phases

A

DTPA has 100% glomerular filtration

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39
Q

Phaeochromocytoma imaging

MIBG can tell benign from malignant
Octreotide can tell benign from malignant
PET can tell benign from malignant
Pheo does not drop signal on out of phase

A

Pheo does not drop signal on out of phase – Markedly hyperintense on T2 (light bulb

PHEO MRI

T1: slightly hypo to the remaining adrenal

More heterogenous if necrotic/haemorrhagic

T2: markedly hyperintense (light-bulb sign) ~1/3 will not have this

Necrosis and haemorrhage will alter the signal

In-phase/out of phase: no signal loss. Pheos do not contain a large amount of intracellular lipid

Heterogenous enhancement - prolonged, often up to 50min

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40
Q

Which determines cardiac artery dominance

Posterior descending artery
SA node supply?
AV node supply?

A

Posterior descending artery

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41
Q

Suspect implant rupture, best initial investigation

Mammography
US
MRI
CT?
Clinical exam?

A

US

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42
Q

Most recurrent breast cancers after treatment detected by

Patient self-examination
Surgeon
Mammography
Ultrasound

A

Patient self-examination

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43
Q

Young girl (21 perhaps) with long history of headache, with cystic frontal lobe lesion containing a calcified mural nodule

Ganglioglioma
Pilocytic astrocytoma
Oligodendroglioma

A

Ganglioglioma - common in younfer patients

GANGLIOGLIOMA

A partially cystic mass with an enhancing mural nodule is seen in ~45% of cases

Frequently calcified

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44
Q

65 yo woman with arm symptoms (?). MRI spine shows a 6.5 mm intramedullary lesion at the C6 level, slightly to the left, and a further 5 mm lesion at T6, in the central cord. Both enhance after gadolinium:

Astrocytoma
Ependymoma
Haemangioblastoma?
Metastases 

A

Metastases 

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45
Q

Cystic lesion deep to parotid extending to parapharyngeal space

1st brachial cleft cyst
2nd branchial cleft cyst
3rd branchial cleft cyst
Lymphangioma

A

1st brachial cleft cyst

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46
Q

Harlequin eye. Which fusion likely?

Metopic
Coronal
Sagittal
Mendosal
Lambdoid

A

Coronal

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47
Q

 65 yo man with mass centred on cribriform plate, growing/invading into anterior cranial fossa and upper nasal cavity (?). Dx?

Esthesioneuroblastoma
Lymphoma 

A

Esthesioneuroblastoma - bimodal (10-20, 50-60)

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48
Q

15 yo girl with right sided abdominal pain. Mildly to moderately tender right iliac fossa. Ultrasound shows enlarged mesenteric lymph nodes. Appendix not seen. What is true of intussusception :

12 hour duration is contraindication to pneumatic reduction

X-rays usually demonstrate no abnormality

Viral gastroenteritis is a recognized risk factor

Small bowel obstruction is a contraindication to pneumatic reduction

A

Viral gastroenteritis is a recognized risk factor

Performed in paediatric patients with an ileocolic intussusception

A catheter is inserted into the rectum, and under fluoroscopic guidance air is instilled into the large bowel

IV access, staff and equipment for fluid resuscitation with the back up of a paediatric surgeon

Pressure 60-100mmHg are used: 3 attempts lasting 3 minutes

Success is achieved which reduction of the mass and air refluxes into the terminal ileum

Contraindications:
Signs of peritonitis
Perforation

Complications:
Less likely to be successful if:
Associated SBO
Over 24hrs of symptoms
lethargy

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49
Q

Best way to tell infection from Charcot joint :

Effusion with thin rim of enhancement
Sinus tract to bone

A

Sinus tract to bone

CHARCOT JOINT
Density change (subchondral osteopenia or sclerosis)
Destruction (osseous fragmentation and resorption)
Debris (intra-articular loose bodies)
Distension (joint effusion)
Disorganisation
Dislocation (joint mal-alignment due to ligamentous laxity

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50
Q

Patient with past history of metastatic breast cancer. Constant shoulder pain. Normal x-ray. Best test

Ultrasound

CT

MRI

NM bone scan

?

A

MRI

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51
Q

14 yo fat kid has a sore knee. Third presentation, previously x-rays of knee normal. For repeat knee xray. What would you do?

AP and lateral knee x-ray
AP and lateral hip x-ray

A

AP and lateral hip x-ray ? SCFE

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52
Q

Regarding non-accidental injury

Bone scan will become positive after x-ray changes are visible

Anterior rib fractures are more common than posterior

Long bone spiral fractures are typical

Metaphyseal corner fractures associated with twisting injuries

A

Long bone spiral fractures are typical? if non ambulatory very sus….

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53
Q

 Patient from rheumatology clinic with infraspinatus wasting. Most likely

Ganglion cyst at suprascapular (?) notch

Ganglion cyst at spinoglenoid notch

A

Ganglion cyst at spinoglenoid notch

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54
Q

Traumatic knee dislocation:

Common peroneal nerve is more commonly injured than Tibial nerve

DSA is necessary in all patients to rule out vascular injury

Can occur without fractures

Patellar tendon is always completely torn

A

Answer: Common peroneal nerve is more commonly injured than Tibial nerve

Can occur without fractures

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55
Q

Child with previous history of meningococcal meningitis, now with unilateral sensorineural hearing loss

Otosclerosis
Some other kind of otosclerosis
Labyrinthitis ossificans

A

Labyrinthitis ossificans

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56
Q

Thyroid nuclear medicine imaging :

De Quervain shows low uptake initially

High uptake in factitious thyroiditis

Low uptake in TSH driven thyroidititis

Toxic nodule demonstrates increased uptake of surrounding thyroid tissue

A

Answer: De Quervain shows low uptake initially - The initial thyrotoxic phase is associated with thyroid pain, high serum thyroid hormone levels with a low radioiodine uptake.

High uptake in factitious thyroiditis – Will be low

Low uptake in TSH driven thyroidititis – No it is high

Toxic nodule demonstrates increased uptake of surrounding thyroid tissue

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57
Q

Nigerian man with bladder calcifications and a soft Tissue mass. Most likely?

SCC

TCC

Adenocarcinoma 

A

SCC

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58
Q

Best sequence for assessing bladder cancer invasion

T1
T2
PET/CT
CECT
US

A

T2 - this is best, T1 rubbish in pelvis ex for l/nodes!

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59
Q

55 year old male with basal ganglia haemorrhage.

Hypertension

Amyloid angiopathy

Underlying lesion

A

Hypertension

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60
Q

Young female with positive beta-HCG. Has pain and ultrasound shows a 5cm heterogeneous mass in the adnexa. Trace fluid in the pelvis

Haemorrhagic corpus luteal cyst
Ruptured ectopic pregnancy
Unruptured ectopic pregnancy
Normal corpus luteum
Haemorrhagic cyst

A

Unruptured ectopic pregnancy

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61
Q

Biopsy proven radial scar, next step

a. WLE + SLNBx

b. Hook wire + Open biopsy

c. Nothing

d. Follow-up imaging

A

b. Hook wire + Open biopsy

Considered a high-risk breast lesion. Core and FNA underestimate the underlying associated malignancy and are controversial > the lesion is biopsied and removed

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62
Q

PASH benignity?

A

a. Always benign

Pseudoangiomatous stromal hyperplasia. Benign stromal proliferation

likely hormonal driven as only seen in premenopausal women or post-menopausal
women on HRT.

Proliferation of myofibroblasts and stromal elements.

Can mimic a mass.

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63
Q

Lobular ca

Only visible on one view –

Not visible on US -

A

Answer: Only visible on one view –

most commonly seen as a spiculated mass on mammography (50-68%) but other findings include occult mass, only-visible-on-one view focal density (3-19%) or architectural distortion (20%). ILC represents 10-15% of breast carcinomas. Sensitivity on mammography is 71%.

Not visible on US - Usually a mass lesion with irregular borders and acoustic shadowing 60%. Sensitivity is 88%. (MRI 93%).

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64
Q

Some breast lesion complicated by some other lesion due to radiotherapy, what do to

Total mastectomy

Cut out the lesion

A

Answer: Total mastectomy – If suspect angiosarcoma -> core -> mastectomy

Secondary angiosarcoma, related to prior therapy of breast cancer, has an estimated incidence of ~0.09-0.16% and occurs in older women (peak age 6th decade).

Can be occur on mammography

Surgical excision with wide margin is the standard of care, typically a mastectomy.

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65
Q

Patient presents to breast screen with symptoms, which is most concerning?

Bilateral nipple retraction

Cyclical pain

Focal pain

Serous nipple discharge

Milky nipple discharge

A

ANSWER: Serous nipple discharge - Likely a DCIS esp unilateral

Bilateral nipple retraction – can be pre-existing
Cyclical pain - Pain less concerning, especially cyclical
Focal pain - Less concerning
Milky nipple discharge Normal during pregnancy

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66
Q

Tubular breast cancer most true

Can be stable on imaging over years

Comprised of >90% well-formed tubules.

70% 10 yr survival

A

ANSWER: Can be stable on imaging over years - slow growing with low metastatic potential.

70% 10 yr survival : False higher survival rates (95-98% at 5 years)

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67
Q

Obese lady, cant get pregnant what will you find

10 (!) cysts, small

Bilateral mixed echoic lesions

Hydrosalpynx

A

ANSWER: Bilateral mixed echoic lesions (chose that for endometrioma, but might be wrong)

The most common overall cause of female infertility is the failure to ovulate, which occurs in 40% of women with infertility issues. Not ovulating can result from several causes, such as: Ovarian or gynecological conditions, such as primary ovarian insufficiency (POI) or polycystic ovary syndrome (PCOS)

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68
Q

Rotterdam criteria, what is not included?

Cysts individually >10mm

> 12 cysts

Hyperandrogenism

Anovulation

Peripherally distributed cysts

A

ANSWER: Cysts individually >10mm – they are small cysts

> 12 cysts - True then however no longer true
Hyperandrogenism - True
Anovulation - True
Peripherally distributed cysts - True

The diagnosis of PCOS generally requires any two of the following three criteria for the diagnosis, as well as the exclusion of other aetiologies (e.g. congenital adrenal hyperplasia, Cushing syndrome, and/or an androgen-secreting tumour):
- ovulatory dysfunction (oligo- or anovulation)
- clinical and/or biochemical hyperandrogenism
- polycystic ovarian morphology on ultrasound

Features include:

increased follicle number per ovary (FNPO) - usually 20 or greater

individual follicles are generally similar in size and measure 2-9 mm in diameter

peripheral distribution of follicles; this can give a “string of pearls” appearance

background ovarian enlargement (volume greater than 10 mL)

central stromal brightness +/- prominence

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69
Q

Antenatal scan at 7 weeks gives gestational age of 35 weeks. Scan at second trimester gives gestational age of 33 weeks. Foetus currently measuring 32 weeks. Most correct:

Use 7 week scan, foetus small for gestational age

Use 2nd trimester scan, foetus is within normal size limit

Use 2nd trimester scan, foetus is small for dates

A

Use 7 week scan, foetus small for gestational age

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70
Q

Middle aged woman with 1.5cm echogenic renal lesion on ultrasound. On MR lesion is T1 and T2 intense with no enhancement. MOST LIKELY

Haemorrhagic cyst

Proteinaceous cyst

Angiomyolipoma

Renal cell carcinoma

A

ANSWER: Proteinaceous cyst

Haemorrhagic cyst - Should have a fluid-fluid level.

Angiomyolipoma - Heterogenous on T1 and T2 imaging due to variable amounts of fat and muscle. Variable enhancement, usually hypoenhancing relative to renal parenchyma.

Renal cell carcinoma – unlikely to have no enhancement

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71
Q

HSV encephalitis

HSV 1 most common in adults

Haemorrhagic necrosis common

HSV 1 most common in kids less than 10

A

ANSWER: HSV 1 most common in kids less than 10 True - Neonatal HSV is HSV-2 but childhood is usually HSV-1.

HSV 1 most common in adults True
Haemorrhagic necrosis common True

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72
Q

NF1, false

Lisch nodules
Meningioma
Neurofibroma
Freckles

A

Meningioma - False

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73
Q

15 yo with seizure. Hypodense cortical lesion. Cystic

A

ANSWER: DNET Multicystic

WHO grade 1, sharply demarcated and often points towards the ventricle, temporal lobe most common.

30% demonstrates focal or ring enhancement.

Very T2 bright.

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74
Q

Teenager with cystic lesion under chin with multiple hypodense nodules (repeat)

A

ANSWER: Dermoid (ranula just fluid, won’t have fat)

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75
Q
  1. Patient with hyperthyroidism, next step

Tc99 Pertechnetate
MRI
US
CT with contrast
I131 diagnostic test

A

Tc99 Pertechnetate

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76
Q

Pancreatic lesion. Hepatic lesions: one heterogenous, one hyperdense, one hypodense, which one biopsy? (repeat)

A

ANSWER: Heterogenous hepatic lesion

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77
Q

Pancreatic lesion with multiple cysts (more than 6), measures 4 cm. Location not mentioned. Age not mentioned. Most likely?

IPMN

SPEN

MCN

SCN

A

ANSWER: SCN

IPMN Possible but less likely
SPEN Usually more solid/cystic with haemorrhagic component
MCN Multiloculated but usually large (up to 12cm)

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78
Q

Gallbladder ca least likely :

Generalised thickening
Old person with otherwise normal

A

ANSWER: Old person with otherwise normal

Virtually all have gallstones
20% polypoid mass
Mass replacing gallbladder invading liver 2/3
Irregular focal or diffuse GB wall thickening 20%
Calcified gallstones or porcelain gallbladder
Elderly females
Usually asymptomatic – often an incidental finding or found due to disseminated metastatic disease
Very poor survival rates, 4% 5 year survival

DDx:
Xanthogranulomatous cholecystits
Adenomyomatosis
Chronic cholecystitis

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79
Q

Chest lesions after trauma

A

Splenosis - can occur in the thorax if there is diaphragmatic injury

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80
Q

Associations, true

This strange worm with duodenal obstruction

Strongyloidiasis produces duodenal dilatation and wall thickening

A

ANSWER: This strange worm with duodenal obstruction - Ascaris Lumbricoides known for causing biliary tract and small bowel dilatation, can also cause hepatic abscesses and ascaris pneumonitis

Ascaris Lumbricoides
Large round worm – can block the bowel

Severe cases such as hyperinfection syndrome (HS) and disseminated strongyloidiasis (DS), can involve pulmonary manifestations.

Spectrum of changes that can involve the lung include
pulmonary infiltrates with eosinophilia
asthma without infiltrates
haemoptysis: from alveolar haemorrhage
hyperinfection syndrome
acute respiratory distress syndrome
lung abscess formation
interstitial infiltrates/fibrosis
cavitary lesions

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81
Q

Todani classification, dilation of intra-duodenal bile duct?

1
2
3
4
5

A

3

1: Fusiform dilatation of the extrahepatic bile duct
A - entire duct
B - focal segment
C - common bile duct

2: Bile duct diverticulum - saccular outpouching arising from the supraduodenal extrahepatic bile duct or the intrahepatic bile ducts

3: Choledochocele - protrusion of a focally dilated, intramural segment of the distal common bile duct into the duodenum

4: Intra and extra-hepatic duct cysts

4a - Fusiform dilatation of the entire extrahepatic duct with dilataion of the intrahepatic bile ducts

4b - multiple cystic dilations involving only the extrahepatic bile duct

5: Caroli disease, cystic dilation of the intrahepatic ducts

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82
Q

Young Asian girl, right iliac fossa pain, on US see pouch like structure arising from anterior caecal wall, with highly echogenic structure within, most likely

Appendicitis

Crohns

Caecal Diverticulitis

Mesenteric adenitis enlarged lymph nodes

A

Appendicitis

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83
Q

Old guy, CT abdomen shows fusiform AAA with thick wall, raised ESR, most likely

Inflammatory aortitis

Mycotic aneurysm

A

ANSWER: Inflammatory aortitis

Mycotic typically a saccular aneurysm, 75% due to salmonella . 95% are AVSD – usually fusiform

Inflammatory aneurysm – patients typically around 10 years younger (50s), risk of rupture is less, they are symptomatic before rupture with back pain, 90% have an elevated ESR, inflammatory change centred on the adventitial with infiltrate of inflammatory cells including lymphocytes, macrophages and plasma cells and fibrosis. Often relative sparing of the posterior wall of the aorta. Can be isolated and may be autoimmune, or part of IgG-4 disease with renal hydronephrosis.

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84
Q

Multiple hyperdense nodules in lung most likely?

Renal osteodystrophy
Sarcoid
Mets

A

ANSWER: Renal osteodystrophy Could be metastatic calcification

Sarcoid Less likely. Lymph nodes – 20% calcify. Lung nodules less frequent

Mets Could be

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85
Q

Sarcoid least likely

Lower lobes affected

Upper lobes affected

Some other stuff???

A

ANSWER: Lower lobes affected

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86
Q

TB T/F

Calcified apical
Ghon focus
Miliary lung lesions

A

ALL TRUE

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87
Q

Elderly male CTA post AAA stent. Mildly hyperdense leak thought to be due to graft porosity

Endoleak, which one?
1
2
3
4
5

A

ANSWER: 4

A common complication of EVAR, found in 30-40% intra-operatively, and 20-40% post operatively

Several causes:
1 - leak at graft attachment site
1A - proximal
1B - distal
1C - iliac occluder

2 - aneurysm sac filling via branch vessels
2A - single vessel
2B - two vessels or more

3 - leak through defect in the graft
3A - junctional separation of the modular components
3B - fracture or holes involving the endograft

4 - leak through graft fabric as a result of graft porosity, often intraoperative and resolves with cessation of anticoagulants

5 - continued expansion of aneurysm sac without demonstrable leak on imaging

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88
Q

Regarding berry aneurysms, not true?

Most are anterior

Complication due to vasospasm in first 24 hours

A

ANSWER: Complication due to vasospasm in first 24 hours False 4-14 days post SAH, peaking at 7 days typically

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89
Q

Newborn (sex not provided), brother DDH, best management (rep)

US in 6 weeks

Xray in 2 month

A

ANSWER: US SIX WEEKS

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90
Q

 Newborn, no meconium, ileum meconium filled. Microcolon. Most likely

Meconium ileus
Meconium plug syndrome
Hirschprungs
Ileal atresia

A

ANSWER Meconium ileus

Indicative of cystic fibrosis

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91
Q

Newborn with lung lesion and feeding vessel

Sequestration
CPAM
CDH

A

ANSWER: Sequestration Depends where vessel coming from – sequestration is systemic arterial supply and variable venous drainage (systemic extralobar and pulmonary intralobar)

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92
Q

T21 associated with

A

Hirschprungs

 Others include:
- 40% congenital heart disease – ASD (ostium primum), VSD, endocardial cushion defect
- Oesophageal atresia
- Duodenal atresia
- Imperforate anus
- 10-20x increased risk of childhood acute leukemia (both ALL and AML)
- Early onset Alzheimers disease
- Autoimmune disease and infections
- Umbilical hernias
- Hearing loss (conductive, middle ear infections)
- Atlanto-axial instability
- Moya moya disease

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93
Q

Kid with posterior fossa tumour extending through the 4th ventricle foramina

Hemangioblastoma

Medulloblastoma

Pilocytic astrocytoma

Ependymoma

A

ANSWER Ependymoma

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94
Q

6 months old with eventration of the right hemidiaphragm. Previous cxr normal. Cause?

Mixed CPAM / sequestration

CPAM

Lobar emphysema

Bronchial atresia

A

ANSWER: None of the above

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95
Q

T/F: Neuroblastoma can spontaneously resolve even if metastasised.

A

ANSWERTrue – neuroblastoma, ganglioneuroblastoma and ganglioneuroma can demonstrate spontaneous or therapy induced differentiation into mature neural elements, regression and a wide range of clinical behaviour and aggressiveness.

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96
Q

T2 signal in anterior aspect of medial tibia and femur of the medial condyle. ? mechanism

Hyperextension and varus
Hyperextension and valgus
Flexion and varus
Flexion and valgus
Pivot shift ACL

A

ANSWER: Hyperextension and varus

Flexion and valgus – This is ACL mechanism. Kissing contusion is posterolateral tibial plateau and lateral femoral condyle

Pivot shift ACL – a valgus load applied to a flexed knee with a variable degree of internal rotation of the femur

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97
Q

 Unicameral bone cyst involves :

Epiphyseal location

Metaphyseal intramedullary

Are more common in the femur than the humeru

Usually contain fluid fluid level on MRI

A

ANSWER: Metaphyseal intramedullary – usually central, metaphyseal and medullary

Epiphyseal location - False

Are more common in the femur than the humerus False. Humerus is the most common location.

Usually contain fluid fluid level on MRI – only if there has been a fracture

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98
Q

Unicameral bone cyst, which is most correct: (TW) 2005, 2006

Are more common in the femur than the humerus

Involve the epiphysis in about 30% of cases

Contain fluid fluid levels on MRI in greater than 50% of cases

Arise eccentrically in the metaphysis

Migrate into the diaphysis with time

Arise in the metaphysis

Fallen fragment sign may be seen in half of cases

A

ANSWER: Arise in the metaphysis True

Migrate into the diaphysis with time True – grows with the child, does not cross the physeal Plate

Are more common in the femur than the humerus False – humerus most common location (although calcaneus is the most common in adults)

Involve the epiphysis in about 30% of cases False

Contain fluid fluid levels on MRI in greater than 50% of cases False – this is seen in SBC with a pathologic fracture

Arise eccentrically in the metaphysis False – central lesion

Fallen fragment sign may be seen in half of cases False

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99
Q

 Best test for check of infected prosthesis (repeat)

MRI

White cell scan

A

White cell scan

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100
Q

Otherwise healthy man with sudden back pain during gardening. What to do next?

No imaging for 6 weeks
MRI
Xray - the other option
CT lumbar spine

A

No imaging for 6 weeks – if no red flags present otherwise do an x-ray

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101
Q

Young female runner, hip pain for several months, impacting on her professional running. Improves with rest. MR shows high signal in region of anterior femoral neck which tracks toward lesser trochanter, most likely?

Snapping gluteus maximus

Trochanteric bursitis

Tear at iliopsoas

A

ANSWER: Tear at iliopsoas

Snapping gluteus maximus – happens externally over greater trochanter

Trochanteric bursitis - Unlikely to cause bone marrow oedema. Does improve with rest.

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102
Q

Avascular necrosis, which one is not a cause?

Thalassemia Major
Sickle cell anaemia
Caisson
Gaucher
Subcapital femoral fracture

A

ANSWER: Thalassemia Major

Aetiology
Traumatic - usually unilateral
Chronic corticosteroid therapy
Alcoholism
Smoking
Systemic lupus erythematosus (SLE)
Hyperlipidaemia
HIV
Haemoglobinopathies
Chronic renal failure
Diabetes Mellitus
Pregnancy-related

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103
Q

Define Prevalence a true positive b true negative, c false positive, d false negative, n total population

a / a+b

b / a+c

a + d / n

a +c / n

A

ANSWER: a + d / n

number of cases (true positive+false negative)/total population)

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104
Q

You want to MR with contrast on a patient with egfr 29, what to do

Macrocyclic gadolinium
Linear gadolinium
Do not give contrast

A

ANSWER: Macrocyclic gadolinium (true) true – cyclic contrast agents reduce risk

Linear gadolinium false – linear agents are less stable and increase risk to dialysis immediate after
Can be considered hemodialysis reduces amount of gad by 75% but no proof it reduces chance of NSF

Do not give contrast False – risk of NSF is sGll low at <0.1% per dose

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105
Q

You do a lung biopsy, as you withdraw stylet patient coughs and has a seizure ? cause

Air embolus

Anaphylaxis

A

Air embolus

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106
Q

IV contrast anaphylaxis post CT, what to give?

IM adrenaline 1:1000, 0.5ml

IV adrenaline 1:1000, 0.5ml

Chlorprometazine

Other drugs

A

IM adrenaline 1:1000, 0.5ml

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107
Q

 Access for permacath type of tunnelled CVL

Right IJV

Leo IJV

Right suclavian

Leo subclavian

A

Right IJV

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108
Q

Man with suspected pancreatic cancer is coming for an image guided biopsy. He is a type 2 diabetic on metformin and also on clopidogrel and clexane. Normal renal function. What advice do you give prior to biopsy.

Stop clopidogrel 10 days? prior, clexane 12 hours prior.

Stop clopidogrel 12 hours prior and clexane 10 days prior

Stop metformin 48hrs prior and clopidogrel 10 days prior?

Stop metformin 24hrs prior

Stop metformin 48 hrs prior and clexane 12 hrours prior?

A

ANSWER Stop clopidogrel 10 days? prior, clexane 12 hours prior. Answer (although usually only need to stop clopidogrel for 5 days)

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109
Q

Mag 3 scan for renal function, what do you explain to the patient (repeat)

Injection, immediate imaging for 30 minutes

Injection, immediate imaging for 3 hours

Injection, scan after 24 hours

Injection scan after 48 hours

A

Injection, immediate imaging for 30 minutes True

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110
Q

Young chap with cough and fever, what would the VQ scan look like

Multiple matched defects

Multiple mismatched defects

Intact perfusion, decreased ventilation

A

ANSWER: Multiple matched defects - seen in Pneumonia

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111
Q

35 yo male lesion inferior to lesser trochanter peripheral cal, centrally hypodense, faint curvilinear calcs, femoral cortex intact:

Osteosarc -

Periosteal chondroma

Osteochondroma

(? myositis ossificans)

A

ANSWER: (? myositis ossificans)

Osteosarc - unlikely
Periosteal chondroma – saucerisation : possible
Osteochondroma - also unlikely

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112
Q

 Acute onset confusion in 65 yo female, inferior mesial temporal lobe with DWI restriction and T2 high signal:

MCA stroke

HSV

paraneoplastic syndrome

CADASIL

A

ANSWER: HSV: only if it spares the basal ganglia

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113
Q

 Young guy with grey white matter differentiation, partying, thunderclap headache, LP had nothing, CT had grey white matter loss in frontal lobe:

Cerebral venous thrombosis

RCVS

Berry aneurysm

A

ANSWER: RCVS - thunderclap headache makes this possible, but CVT also possible

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114
Q

Stented left ICA, bilateral frontal infarcts repeat:

A

Azygos vessel A1

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115
Q

Kid with seizures, T2 high signal, bubbly:

A

DNET

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116
Q

35 yo repeated seizures, T2 high signal mesial temporal lobe, assoc:

Ipsilateral fornix atrophy

contra fornix atrophy

mamillary body hypertophy

choroidal atrophy

A

Ipsilateral fornix atrophy

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117
Q

Tectal beaking is assoc with what:

Chiari 2
Chiari 1
DWM
Agenesis of CC
Holoprosencephaly

A

Chiari 2

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118
Q

5 yo girl with midline 4th ventricle tumour extending through foramina with some calc:

Ependymoma

JPA

Medullo

A

Ependymoma ( calc 30-40%)

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119
Q

 Most likely tumour arising from septum pellucidum in lateral ventricle in 40 yr old:

Central neuryoctyoma

Meningioma

metastasis

Choroid plexus lesion

A

Central neuryoctyoma

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120
Q

 Most likely tumour arising from septum pellucidum in lateral ventricle in 40 yr old:

Central neuryoctyoma

Meningioma

metastasis

Choroid plexus lesion

A

Central neurocytoma

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121
Q

5 yr old with lump mixed echos

dermoid

Ranula

4th BCC

Lymphangioma

A

dermoid if its this repeat one

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122
Q

Location of a lymph node between hyoid and base of skull anterior to post SCM

A

2a

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123
Q

Young guy with SOB, CL nodules and GG change non-smoker:

Sarcoid
HP
OP
DIP
NSIP

A

HP

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124
Q

 What’s the appearance on VQ in pneumonia:
recall, reverse mismatch, matched multiple perfusion, large, etc

A

multiple matched perfusion

V/Q: Results -

Ventilation Scan is abnormal but perfusion scan is normal indicating abnormal airway suggesting COPD or ASTHMA.

Ventilation Scan is normal but perfusion is abnormal indicating any obstruction to the blood flow (perfusion), may be because of the PULMONARY EMBOLISM obstructing the flow.

Both scans are abnormal. It may be found in PNEUMONIA or COPD.

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125
Q

24 yo female marathon runner VQ scan low probability and CXR normal:

No further imaging

CTPA,

VQ in 1 wk,

Do US bilateral legs

A

no further

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126
Q

Young fit guy with back pain while gardening, afebrile, otherwise well:

Do nothing

MRI

XR

CT

A

do onthign

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127
Q

Soft hard q about 1.5T vs 3T:

More susceptibility weighted artefact,

Dropout on out of phase on 3t is higher,

300 Gauss is further from the bore,

Fluid higher on T1 GRE than grey maber on 3T

A

300 Gauss is further from the bore,

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128
Q

Mid ileal dilation and 5cm strIcturing distally:

Crohns
Carcinoid,
Coeliac,
Scleroderma,
Lupus

A

Crohns

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129
Q

Lesion in ileum with desmoplastic reaction:

Carcinoid,
Adenocarcinoma,

A

Carcinoid,

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130
Q

Repeat: re barium study:

Increase jejunal folds in coeliac

Whipples has thickened nodular folds

Haematogeneous mets occur at mesenteric border

A

ANSWER: Whipples has thickened nodular folds

Increase jejunal folds in coeliac, F (jejunal smooth, ileum folded)

Haematogeneous mets occur at mesenteric border -F

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131
Q

Intraduodenal cyst continuous with CBD:

I,
II,
III
IV,
V

A

3

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132
Q

Which is more common in UC vs CD:

Pseudopolyps
Episcleritis,
Nephrophthisis,

A

Pseudopolyps

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133
Q

Least common with Ank spond:

MTP involvement
Uveitits

A

MTP involvement

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134
Q

Prevalence calculation a= TP b=FP, c= TN, d = FN, N = total number:

a+b/N,

a+d/N

b+c/N, c+d/d, etc

A

a+d/N

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135
Q

Thickening of gastric rugal folds with preservation - recall:

MALToma –

gastric adenocarcinoma intestinal type,

gastric adeno ca infiltrating (linitis plastica),

GIST

A

MALToma –

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136
Q

Rpt about pancreatic ca:

> 90% can detect unresectale on CT
Vascular and perineural invasion,
Most commonly in the head - 70%
body and tail are spared

A

ANSWER >90% can detect unresectale on CT

OR Most commonly in the head - 70%

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137
Q

Porosity leak in aortic graft. what is the most common endoleak (very sneaky quesGon)

Type I,

II

III,

IV,

V

A

4

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138
Q

 Repeat about guy with MEN and diffuse dense pulmonary nodules with uptake on bone scan:

Metastatic pulmonary calcification, -

Sarcoid,

Aleveolar microlithiasis,

Other

A

Metastatic pulmonary calcification, -

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139
Q

Knee injury, contusions on anterior medial femur and medial tibia:

Valgus with extension,

Varus with ext

Valgus with lfexion,

Varus with flexion,

Pivot shio

A

Varus with ext

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140
Q

CT cystogram with contrast in perineum and extraperitoneal space, most likely injury to:

Bladder base,

Bladder dome,

prostatic urethra,

bulbous,

Membranous

A

Membranous

 - if perineum + extra peritoneal = membranous

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141
Q

Rpt about diffusely thickened and irregular uterus:

Adenomyosis,

Fibroids,

some others

A

Fibroids,

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142
Q

Guy with previous rheumatic fever, presents with heart failure, fever, meningeal symptoms, what is most likely:

Ring enhancing cerebral lesions,

Leptomeningeal enhancement, ??

A

Ring enhancing cerebral lesions,

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143
Q

Lady with sudden onset headache, diplopia, ct shows nodular thickening of lateral rectus with no enhancement:

Spontaneous lateral rectus haematoma,

Inflammatory pseudotumour,

Sarcoid,

Thyroid ophthalmopathy

A

Spontaneous lateral rectus haematoma,

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144
Q

Lady with medial canthus thickening and pain, CT shows ring enhancing hypodense lesion in medial canthus:

Dacrocystocele –

Inflammatory pseudotumour,

Thyroid?

A

Dacrocystocele

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145
Q

High T3, high T4, low TSH, next test?

US .
NM- pertecnetate study
MRI,
CT

A

NM- pertecnetate study. Patient has Graves

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146
Q

 Inflammatory pseudotumour involves all except? rpt:

Brain
Cavernous sinus,
Lacrimal gland,
Orbital apex,
Orbital muscles (

A

Brain

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147
Q

What is the most common tumour of the distal small bowel?

A

Carcinoid

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148
Q

Subperiosteal resorption on radial side of fingers, other HPTH things, most likely:

Osteopetrosis,

Pyknodysostosis,

Renal osteodystrophy

A

Renal osteodystrophy

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149
Q

Rpt most true about cholesteatoma:

Small most commonly in prussak space

Scutum of erosion should think of different pathology

A

Small most commonly in prussak space

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150
Q

Rpt: guy with headache, expansion of petrous apex, high T1 and T2 lesion:

Cholesterol granuloma
Metastasis,
Chondrosarcoma,
Petrous apicitits,
High jugular bulb

A

Cholesterol granuloma

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151
Q

Rpt about spine least likely:

one of the answers was about limbus vertebra being anterosuperior, - typically

chance fracture always assoc with neurology

flexion injury with ventral cord injury

A

chance fracture always assoc with neurology

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152
Q

Kid with no passed meconium, contrast enema shows microcolon with filing defects in ileum and asC colon:

meconium plug - “syndrome”

meconium ileus

hirschsprungs, ileal atresia

A

meconium ileus – Ans, commonly in TI, CF

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153
Q

 Expected AXR findings in NEC:

various answers to do with bowel wall thickening,

Intramural gas

A

Intramural gas

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154
Q

 Immigrant 5 yr old with lucent lung, which is true to identify abnormal lung:

Increased vasc = normal side ( in swyer james)

Enlarged PA = abnormal side,

Change on exp = abnormal side,

If lung herniates to one side that side is abnoral,

If lucent side is on side of caridac apex, that is abnormal

A

Increased vasc = normal side ( in swyer james)

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155
Q

Which is not a part of PCOS:

> 12 follicles (now 20),

Follicle > 10mm size

Peripheral distribution of follicles,

Hyperandrogenism,

Anovulation

A

Follicle > 10mm size

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156
Q

 25 yo girl unable to get pregnant (rpt) what is most likely on tVUS:

A

varieties of anechoic cysts on one or both ovaries, and >10 follicles on both ovaries

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157
Q

Cant remember stem, might be part of 2qs:

OA involves medial and lateral equally

CPPD preferentially involves PFJ

Early articular cartilage degeneration in ?CPPD, involves both sides of joint

A

CPPD preferentially involves PFJ

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158
Q

 35 yo guy with pain in elbow while lifting weight, has bruising and limited elbow flexion:

Biceps tendon musculotendinous junction tear,

Biceps tendon insertion tear

Brachialis tear,

CFO/CEO tear?

A

Biceps tendon musculotendinous junction tear,

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159
Q

 Kid with ulnar coronoid fracture, radial head fracture, elbow dislocation, what is most likely injured:

RCL ,

CEO,

Lat ulnar collatera

A

Lat ulnar collateral (unhappy triad)

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160
Q

Atypical ductal hyperplasia, had breast MR which was normal, what to do next:

back to normal screening,

6 months and yearly screening,

mastectomy,

some type of excision biopsy after localisation - hook wire and something

A

some type of excision biopsy after localisation - hook wire and something

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161
Q

Trauma, guy has haematuria, no perinephric collection but there is reduced attenuation of kidney, next step:

Cath angiogram

Thrombolysis,

repeat CT tomorrow,

some other treatment

A

Cath angiogram - CT angiogram if an option

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162
Q

Not spiculated:

Tubular,

Medullary

ILC,

??IDC

A

Medullary

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163
Q

Someone with AML, most likely assoc?

LAM

Cutaneous angioma,

Ependymoma,

Phaeochromaocytoma (may be path)

A

LAM

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164
Q

Regarding AVN (RPT):

MRI picks up changes earlier than Tc99m,

Early xr change is subchondral lucency,

Early cartilage loss, most get degen on both sides of joint

A

MRI picks up changes earlier than Tc99m

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165
Q

 RPT true re parathyroid:

T2 best at finding parathyroid adenoma,

Most common ectopic parathyorid is superior to thyroid,

A

T2 best at finding parathyroid adenoma,

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166
Q

RPT UBC is most commonly:

Intramedullary metaphyseal,

Epiphyseal,

some others

A

Intramedullary metaphyseal,

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167
Q

 Most common cause of pseudomyxoma peritonei

Appendiceal mucocele

Appendiceal mucinous cystadenocarcinoma

Mucinous ovarian tumour

A

Appendiceal mucinous cystadenocarcinoma

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168
Q

Least associated with NEC

Premature

Initiation of enteral feeding

Intramural gas descending and sigmoid

A

Intramural gas descending and sigmoid

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169
Q

Ischaemic bowel, most specific finding

Bowel dilation

Intramural gas

Fixed small bowel

A

Intramural gas

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170
Q

6 months old – posterior and medial bowing of tibia and fibula

NF

Physiological (peak 6-12 mo)

Fibrocartilaginous dysplasia - varus deformity

Blounts

A

NF - if pseudoarthrosis basically NF1, anterolateral

Blounts
Congenital assoc with leg length discrepancy (post medial likely congenital)
Anterior is bad, posterior is good

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171
Q

 Recurrent lateral ankle inversion and posterior and lateral swelling, most likely injury

ATFL

AInferior TFL

Spring ligament

Deltoid

PTFL

A

PTFL

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172
Q

65M with knee pain, most likely association

Asymmetrical patellofemoral suggests CPPD

OA affects medial and lateral comps evenly

Ossification of the meniscus with HADD

A

Asymmetrical patellofemoral suggests CPPD

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173
Q

Parathyroid adenoma, most useful for localising

MRI with T2 most sensitive

Don’t demonstrate gad uptake

Tech 99 pertechnetate

US

A

MRI with T2 most sensitive

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174
Q

Most likely for gout

Aspiration was clear

Gouty tophi within 1-2years

First episode polarticular

Myelogenous disease recognised cause of gout

A

Myelogenous disease recognised cause of gout

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175
Q

6yr M – bone resorption radial 2nd and 3rd phalanges, prominent trabeculae, widening of epiphysis

A

Renal osteodystrophy

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176
Q

40M – HIV – multiple small hyperdense nodules liver and spleen – most likely

Hydatid

Amoeba

Candidiasis

Karposi sarcoma

Gram positive

A

Candidiasis

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177
Q

History of preeclampsia. Relevance of uterine artery dopplers

Second trimester should be low resistance

No predictive value for pre-eclampsia

High resistance near cord insertion placenta

RI <0.9 is normal

A

Second trimester should be low resistance

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178
Q

3yr child, left sided sensorineural hearing loss, CT showed cochlear and vestibule in figure of 8 formation. Cochlear missing septation

Cystic vestibulocholear malformatioN

Large vestibular aqueduct

Cochlear hypoplasia

A

Cystic vestibulocholear malformatioN

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179
Q

Least likely associated

Limbus vertebrae most likely anterior superior endplate

Chance fracture nearly always a/w neurological injury

Cervical flexion teardrop fracture a/w ventral cord injury

A

Chance fracture nearly always a/w neurological injury

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180
Q

Ankylosing spondylitis, least likely associated

Hip, shoulder and knee involvement

MTP/MCP involvement

Inflammation of annulus fibrosis

A

MTP/MCP involvement

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181
Q

IVDU. Headache. Normal CT brain. No bleed on LP. Presents with stroke like symptoms

RCVS

SAH

A

RCVS

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182
Q

MRI brain. High T2 signal spaces, non-enhancing. Leptomeningeal enhancement/thickening around the base of skull

Cryptococcosis

Neurocysticercosis

Metastases

Lymphoma

Toxoplasmosis

A

Cryptococcosis

CNS cryptococcosis

Epi: AIDS or people with bird contact

There are three dominant CNS forms to the disease depending on which part of the brain is affected:

meninges: meningitis (leptomeningeal enhancement and pachymeningeal enhancement)

parenchyma: cryptococcomas

perivascular spaces: gelatinous pseudocysts

 Meningitis and cryptococcomas are seen in immunocompetent hosts usually and gelatinous pseudocysts are more common in patients with HIV/AIDS.

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183
Q

Post partum woman with headache. Bilateral low density thalami on MRI. Most likely cause?

Cerebral venous thrombosis

MCA infarcts

Lymphocytic hypophysitis

A

Cerebral venous thrombosis

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184
Q

Cystic lesion adjacent to submandibular gland, between internal and external carotid artery, anterior to SCM

1st branchial cleft cyst

2nd branchial cleft cyst

3rd branchial cleft cyst

4th branchial cleft cyst

A

2nd branchial cleft cyst

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185
Q

Painful eye in female. Diffuse thickening of the medial rectus with surrounding fat stranding, (didn’t state enhancement characteristics)

Thyroid eye disease

Idiopathic inflammatory disease

Systemic connective tissue disease/sarcoidosis

Lymphoma

Rectus sheath haematoma

A

Idiopathic inflammatory disease

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186
Q

ZMC/Tripod fracture, which is TRUE

Medial canthus inferiorly displaced

Upgaze palsy due to entrapment inferior oblique muscle

Ipsilateral facial numbess due to facial nerve involvement

Zygomaticofrontal suture involvement

Facial numbness is as a result of facial nerve injury

A

Zygomaticofrontal suture involvement

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187
Q

Smoker, has bilateral parotid lesions, cystic with fluid levels

Sjogren’s

Warthin’s

Pleomorphic adenoma

A

Warthin’s

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188
Q

Regarding arterial dissections in the neck, which one is true?

Can be traumatic or spontaneous

Most commonly affect the vertebral arteries -

A

Can be traumatic or spontaneous

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189
Q

Which is most likely to have cervical lymphadenopathy

Papillary thyroid cancer

Follicular thyroid cancer

Medullary thyroid cancer

Anaplastic thyroid cancer

Lymphoid something

A

Papillary thyroid cancer – most common, most likely to go to nodes

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190
Q

Least likely cause of pituitary fossa enlargement

Craniopharyngioma

Meningioma

Germinoma

Macroadenoma

Lymphocytic hypophysitis

Aneurysm

A

Lymphocytic hypophysitis

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191
Q

Least likely to be an intraventricular mass?

PXA

Meningioma

Ependymoma

Central neurocytoma

Metastases

A

PXA

Pleomorphic xanthoastrocytoma

Pleomorphic xanthoastrocytomas (PXA) are a type of rare, low-grade astrocytoma (WHO Grade II) found in young patients who typically present with temporal lobe epilepsy.

They usually present as cortical tumours with a cystic component and vivid contrast enhancement. Features of slow growth may be present, such as no surrounding oedema and scalloping of the overlying bone. A reactive dural involvement expressed by a dural tail sign can be found. Calcifications are rare.

Typically these tumours are found in young patients (children or young adults), with a peak incidence in the second and third decade of life (10-30 years).

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192
Q

Old woman. Expanded cord with high T2 signal from C7 to T6, with small enhancing foci

Transverse myelitis

Haemangioblastoma

Metastases

Ependymoma

A

Metastases

TM - no expansion
HGB - no VHL
Epen - different enhancement

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193
Q

Lesions at anterior commissure, non-enhancing, patchy restriction, T2 hyperintense, basal leptoeningeal enhancement (and didn’t mention immunosuppression) (in ?adult male)

Cryptococcus

Toxoplasmosis

Lymphoma

TB

A

Cryptococcus

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194
Q

Young dude, weak left arm. Party and alcohol the night before. No blood on LP. Early loss of grey-white differentiation in the precentral gyrus. What is the most likely diagnosis?

Reversible cerebral vasoconstriction syndrome

PRES

Subarachnoid haemorrhage

CADASIL

Demyelination

PML

A

Reversible cerebral vasoconstriction syndrome

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195
Q

Small tooth like fragment surrounded by an expansile (?lucent/sclerotic) lesion

Odontoma

Dentigerous cyst

KCOT

Ameloblastoma

ABC

Metastasis

A

Ameloblastoma

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196
Q

70yo, posterior fossa mass with vasogenic oedema on CT. What is the most likely diagnosis?

Haemangioblastoma

Meningioma

Metastasis

Medulloblastoma

Pilocytic astrocytoma

A

Metastasis

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197
Q

NMO, which is ?true

Commonly presents with bilateral optic neuritis

Short segment spinal involvement

Strong predilection for males

Simultaneous brain and spinal cord lesions

A

A: Commonly presents with bilateral optic neuritis

Short segment spinal involvement
At least three vertebral segments = “longitudinally extensive”

Strong predilection for males
Older than MS, and female

Simultaneous brain and spinal cord lesions
Often concurrent, but may preceed each other by up to several weeks

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198
Q

Described a petrous apex expansile mass. Low ADC. Low T1, high T2.

Cholesterol granuloma

Abscess

Cholesteatoma

Metastasis

Schwannoma

Meningioma

A

Cholesteatoma

Petrous apex lesions :::

Asymmetrical marrow/asymmetrical pneumatisation
- Non expansile
- Fat intensity on all sequences

Petrous apex cephalocele
- CSF signal intensity on all sequences

Petrous apicitis

Congenital cholesteatoma
- Restricted diffusion

Cholesterol granuloma
- Most common cystic appearing lesion
- High T1 and T2, without fat saturation

Mucocele of the petrous apex
- CT opacification of the petrous apex air cells with expansion of cortical margins
- Hyperintense T2 signal and variable T1
- Possible peripheral enhancement

Benign tumours
- Meningioma
- Schwannoma
- Paraganglioma

Malignant tumours
- Chondrosarcoma
- Chordoma
- plasmacytoma

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199
Q

Regarding parathyroid disease

Most common ectopic location is above superior pole of thyroid

Most sensitive sequence is T2 on MRI

A

Most sensitive sequence is T2 on MRI

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200
Q

Parathyroid adenomas are seen best on which MRI sequence? (repeat)

T1

T2

DWI

Contrast enhanced study

A

T2

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201
Q

Inverted papilloma

Associated with squamous cell carcinoma

Arises from the bony nasal septum

Arises from the olfactory bulbs

Can cause isolated unilateral frontoethmoidal sinus obstruction

A

Associated with squamous cell carcinoma

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202
Q

20 year old male in an MVA, complains of chest pain immediately. CT shows pulmonary contusion and small smooth outpouching at the aortic isthmus with no mediastinal fat stranding or haematoma. Most likely cause?

Ductus diverticulum

Aortic isthmus

Pseudoaneurysm

Aortic transection

Penetrating aortic ulcer

A

Ductus diverticulum

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203
Q

Bicuspid aortic valve with systolic murmur. Most likely associated finding

LV hypertrophy and dilatation

No flow void in aorta

Decreased gradient across aortic valve

A

LV hypertrophy and dilatation

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204
Q

Which is NOT part of the Wells criteria

Pleuritic chest pain

Haemoptysis

Signs/symptoms of DVT

Malignancy

A

Pleuritic chest pain

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205
Q

Lady with left lower leg DVT, gets IVC filter, adequately anticoagulated. 2 days later, complains of SOB/chest pain and has new PE on CTPA. Most likely explanation

Duplicated IVC

Azygos continuation of IVC

Retroaortic left renal vein

Circumaortic left renal vein

A

Duplicated IVC

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206
Q

Post carotid endarterectomy, has new posterior/occipital stroke. Most likely cause

Azygos circulation

Hypoglossal artery

Trigeminal artery

Persistent foetal PCOM

A

Hypoglossal artery

Arises from the distal cervical ICA, usually between C1 and C3.

Passes through an enlarged hypoglossal canal, joints the basilar artery inferiorly

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207
Q

70 year old male 6 months post AAA repair for routine CT, which shows a blush of contrast in the aneurysm sac, in keeping with graft porosity. What type of endoleak is this?

Type I

Type II

Type III

Type IV

Type V

A

Type IV

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208
Q

A 40 year old man MEN I has multiple tiny pulmonary nodules on CXR.

Metastatic pulmonary calcification

Sarcoid

Pulmonary alveolar microlithiasis

A

Metastatic pulmonary calcification

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209
Q

Most associated with cystic fibrosis

Imperforate anus

TOF-OA

Ileal/jejunal atresia

Hypertrophic pyloric stenosis

A

Ileal/jejunal atresia - cystic fibrosis: ~25% of cases

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210
Q

Regarding aortic dissection

5-10% no intimal tear is seen

Intimal tear is usually at the junction of the aortic arch and descending aorta

Tear is between the intima and inner third of the media

A

5-10% no intimal tear is seen

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211
Q

Which is true about SVC syndrome?

It is an acute medical emergency

It can result in acute respiratory distress

Endovascular stents are of little use

Pemberton’s sign is negative

A

It can result in acute respiratory distress - Patients typically present with shortness of breath along with facial and upper extremity edema.

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212
Q

Which of the following does NOT cavitate?

Mycoplasma

Lymphomatoid granulomatosis

Lymphoma

A

Mycoplasma

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213
Q

Which is true?

Aspergillus is associated with colonization of bronchi

Aspergillus can be mistaken for mucormycosis in immunosuppressed

A

both

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214
Q

What disease is not associated with cystic airspaces?

LAM

Emphysema

A

Emphysema

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215
Q

In a patient that needs a dialysis catheter, what vein should be used? (repeat)

Right IJV

Left IJV

Right subclavian vein

Left subclavian vein

A

Right IJV

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216
Q

Regarding sequestration

Intralobar sequestration has its own pleural covering

Intralobar sequestration is supplied by the pulmonary arteries

Extralobar sequestration usually occurs in the left lower lobe

A

Extralobar sequestration usually occurs in the left lower lobe

65-90%

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217
Q

does subclavian artery dissection cause cause thoracic outlet syndrome (repeat from 2012 paper with options like pec minor tunnel)

A

no? this recall sucks ass

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218
Q

HIV patient. Multiple hypodense nodules in liver and spleen

Candida

Necrotic metastases

Pyogenic abscesses

A

Candida

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219
Q

Regarding small bowel tumours, most common

Carcinoid in ileum

Lymphoma in proximal jejunum

SB tumour presents with intussusception

SB tumours are mostly benign

A

Carcinoid in ileum

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220
Q

50 yo man 2 weeks post return from Thailand. Febrile. Liver multiseptated lesion.

Amoebic abscess

Hydatid cyst

Pyogenic abscess

A

Hydatid cyst

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221
Q

45F PHx rectal cancer. MRI liver with hepatobiliary contrast. Lesion is arterially enhancing, demonstrates signal drop out on out of phase, and hypodense to liver on delayed phase

FNH

Adenoma

Hypervascular metastasis

HCC

A

Adenoma

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222
Q

35yo with a smooth narrowing at T11 on barium swallow, with proximal oesophageal dilatation

Achalasia

Eosinophilic oesophagitis

Zenker diverticulum

Cricopharyngeus spasm

Barrett’s oesophagus

Scleroderma

SCC

A

Scleroderma

Otherwise achalasia, but complete closure, not narrowing

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223
Q

2 years post treatment for colorectal cancer. Pre sacral soft tissue thickening/mass. Next best test

MRI pelvis

PET/CT

Repeat imaging in 3-6 months

CT guided biopsy

A

PET/CT

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224
Q

Dilation of the intraduodenal portion of the common bile duct. What Todani classification is this?

Type I

Type II

Type III

Type IV

Type V

A

Type III

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225
Q

35 year old male recently immigrated from Singapore presents with fever and RLQ pain. CT shows several 1 cm areas of fat stranding posterolateral to the right side of the colon, measuring 0 to -300 HU. Most likely cause?

Epiploic appendagitis –

Diverticulitis

Appendicitis

Colitis

A

Epiploic appendagitis – omental infarct is >3cm

Multiple is odd

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226
Q

Most common cause of acute diffuse small bowel ischaemia

SMA thrombus

SMA embolus

SMV thrombus

Aortic dissection

IMA thrombus

A

SMA embolus

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227
Q

Pancreatic head mass, 3 liver lesions. Which lesion(s) should be biopsied? (repeat)

Pancreatic lesion

Heterogeneous liver lesion

Hypoechoic liver lesion

Hyperechoic liver lesion

All of the liver ones

A

Heterogeneous liver lesion

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228
Q

Thickened jejunal folds

Scleroderma

Coeliac disease

Whipple disease

Crohn’s disease

Lymphoma

A

Coeliac disease
Reversal of jejunal-ileal folds, and bowel wall oedema = thickening

Whipple disease
Nodular thickening

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229
Q

Which is most likely to present as a pancreatic head lesion in a male?

IPMN

Serous cystadenoma

Mucinous cystadenoma

Solid pseudopapillary epithelial neoplasia

A

IPMN

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230
Q

Trans-sphincteric anal fistula with abscess

Type 1

Type 2

Type 3

Type 4

Type 5

A

Type 4

1 - simple linear intersphincteric

2 - intersphincteric with abscess or secondary tract

3 - transsphincteric

4 - transsphincteric with abscess or secondary tract within the ischiorectal fossa

5 - supralevator and translevator extension

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231
Q

Calcified bladder with mass, African

TCC

SCC

Adenocarcinoma

A

SCC

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232
Q

What condition causes medialisation of the ureters?

Abdominoperineal resection

Prune belly syndrome

Herniation of the ureter through the sacrosciatic foramen

A

Abdominoperineal resection

Medial displacement:
Upper ureter
- Retrocaval ureter
- Retroperitoneal fibrosis
Lower ureter
- Lymphadenopathy
- Iliac artery aneurysm
- Bladder diverticulum
- Post-surgical esp. AP resection
- Pelvic lipomatosis

Lateral displacement or deviation
Upper ureter
- Lymphadenopathy
- Aortic aneurysm
- Retroperitoneal haematoma
Lower ureter
- Pelvic mass e.g. uterine fibroid

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233
Q

Renal stones in a leukaemia patient are most likely to be of which type?

Uric acid

Cystine

Struvite

Calcium phosphate + calcium oxalate

Pure calcium phosphate

A

Uric acid

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234
Q

Renal lesion, T1 hyperintense, T2 hyperintense, with no enhancement

Haemorrhagic cyst

Proteinaceous cyst

AML

Clear cell carcinoma

A

Proteinaceous cyst

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235
Q

Next best test for intra and extraperitoneal bladder rupture (repeat)

Retrograde cystogram

Urethrogram and cystogram

A

Urethrogram and cystogram

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236
Q

Regarding osteosarcoma, FALSE

50% around knee

Periosteal osteosarcoma has best prognosis

Older individuals get it in mandible

Involves (?metaphysis/metadiaphysis) of long bones

Telangiectatic usually demonstrates fluid-fluid levels on MRI

A

FALSE: Periosteal osteosarcoma has best prognosis

Parosteal DOES

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237
Q

What is the angle in scoliosis?

5 degrees

10 degrees

15 degrees

20 degrees

25 degrees

A

10 degrees

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238
Q

Patient with patellofemoral joint space loss, meniscal chondrocalcinosis. What is another expected finding?

Calcification of pubic symphysis

Rotator cuff calcification

MTP joint erosion

MCP joint erosion

A

Calcification of pubic symphysis

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239
Q

Regarding HADD

Periarticular calcifications

1st MTP juxta-articular erosion

MCPJ destruction

Identified within soft tissue calcifications of scleroderma

Identified within soft tissue calcifications of dermatomyositis

A

Periarticular calcifications

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240
Q

Shoulder MRI. No trauma. High T2 signal in supraspinatus, infraspinatus, teres minor. Normal T1 signal.

Brachial neuritis

Suprascapular nerve compression in spinoglenoid notch

Suprascapular nerve compression in suprascapular notch

Quadrilateral space compression

Chronic ?denervation

A

A: Brachial neuritis - parsonage turner syndrome

Suprascapular nerve compression in spinoglenoid notch - Just infraspinatus

Suprascapular nerve compression in suprascapular notch - Both supraspinatus and infraspinatus

Quadrilateral space compression - axillary nerve: teres minor and, or deltoid muscle

Chronic ?denervation

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241
Q

Woman with PHx breast cancer. Hip pain. MRI shows psoas tendon retraction + anterior soft tissue oedema.

Lesser trochanter metastasis

Iliopsoas tendon tear

Subtrochanteric fracture

Stress fracture

A

Iliopsoas tendon tear

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242
Q

Regarding shoulder ultrasound

Assess supraspinatus in flexion

Subscapular tears are often associated with long head biceps tendon tears

Assess long head of biceps tendon in extension

A

Subscapular tears are often associated with long head biceps tendon tears

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243
Q

Which is INCORRECT about MRI knee

PCL is affected by magic angle

Posterior horn medial meniscal tear more common than anterior

MCL and LCL on same coronal plane

A

MCL and LCL on same coronal plane

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244
Q

Popliteal artery entrapment – false?

Popliteal artery aneurysm does not occur

Lateral (?medial) deviation of popliteal artery on extension

Posterior tibial artery low arterial waveform (?if leg is contracted)

A

Popliteal artery aneurysm does not occur

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245
Q

Soft tissue mass on palm. T1 hyperintense, T2 hyperintense, patchy fat saturation and heterogeneous enhancement

Haemangioma

Lipoma

Schwannoma

Venous malformation

?Haematoma

A

Haemangioma

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246
Q

Where is fatty marrow most likely to be found? (repeat)

Femoral diaphysis

Ribs

Pelvis

Vertebra

Proximal humeral epiphysis

A

Femoral diaphysis -in kids

Proximal humeral epiphysis

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247
Q

Which is not an epiphyseal lesion?

ABC

GCT

Chondroblastoma

CMF

A

CMF

Most chondromyxoid fibromas are located in the metaphyseal region of long bones (60%)

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248
Q

Old lady with THR, hot on bone scan and ?loosening or infection. What should you do next? (repeat)

Aspiration + arthrogram

White cell scan

A

White cell scan

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249
Q

Hypoechoic, compressible mass in the subcutaneous tissues in the plantar aspect of the foot, overlying the 2nd, 3rd and 4th metatarsal heads

Adventitial bursitis

Intermetatarsal bursitis

Morton neuroma

A

Adventitial bursitis - Adventitious bursae are not permanent native bursae. They can develop in adulthood at sites where subcutaneous tissue becomes exposed to high pressure and friction.

INTERMET: BW
MORTONS: BW

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250
Q

12 year old girl. Lucent left hemithorax on CXR. CT shows endobronchial lesion, with some peripheral calcification and homogenous enhancement.

Pleuropulmonary blastoma

Carcinoid

Bronchial adenoma

Adenoid cystic carcinoma

Mucoepidermoid carcinoma

A

Carcinoid

Bronchial carcinoid is the most common primary endobronchial neoplasm; it makes up about 80% of malignant pulmonary neoplasm in children.

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251
Q

3 year old male with leukocoria, orbital lesion with calcifications

Retinoblastoma

Neuroblastoma metastasis

Lymphoma

Coats disease

A

Retinoblastoma

Leukocoria - abnormal white reflection from the retina
Top 4 causes:
Retinoblastoma 58%
Persistent hyperplastic primary vitreous 28%
Coats disease 16%
Larval ganulomatosis 16%

Normal sized eye:
Calcified - retinoblastoma
Non calcified - coats disease

Microphthalmia
Unilateral - persistent hyperplastic primary vitreous
Bilateral - retinopathy of prematurity, bilateral PHPV

Coats disease:
A disorder of weak retinal capillaries resulting in progressive retinal detachment due to exudative sUbretinal collection
CT: margins of the exudate may have a V-shaped pattern similar to retinal detachment
MRI:
T1 high - due to proteinaceous nature of the exudates
T2 high - due to proteinaceous nature of the exudates

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252
Q

Paediatric CXR. Normal pulmonary vascularity.

Coarctation of aorta

TOF

VSD

?AP window

ASD

Truncus arteriosus

A

Coarctation of aorta

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253
Q

3yo with macrocephaly, high signal associated with the anterior commissure, bilateral T2 thalamic high signal, forceps minor T2 hyperintensity and developmental delay. Cause

Alexander disease

Castleman disease

Adrenal leukodystrophy

Canavan

A

Alexander disease

Alexander disease
- Bifrontal white matter which tends to be symmetrical
- Caudate head > globus pallidus > thalamus > brainstem
- Periventricular rim
- Anterior dominance

Canavan:
- Mainly subcortical white matter, involves the subcortical U-fibres
- Globus pallidus and thalami are involved
- Spares the corpus callosum, caudate nucleus, putamen and internal capsule

Adrenoleukodystrophy
- Spares the subcortical U fibres
- Characteristic occipitoparietal periventricular distribution

Metachromatic leukodystrophy
- Spares subcortical U-fibres
- Characteristic butterfly pattern

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254
Q

2 day old, distal bowel obstruction, sacral abnormality

Hirschsprung’s

Ileal atresia

Meconium ileus

Imperforate anus

Meconium plug

A

Imperforate anus

The Currarino syndrome is a complex condition variably comprised of characteristic congenital anomalies of the sacrum, anorectum and presacral soft tissues.

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255
Q

Brainstem mass in 9 y/o

Pilocytic astrocytoma

Fibrillary astrocytoma - old term for diffuse astrocytoma

Medulloblastoma

Ependymoma

Pleomorphic xanthoastrocytoma

A

Medulloblastoma

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256
Q

15yo Fibrillary astrocytoma (repeat)

Pilocytic astrocytoma

Craniopharyngioma

Ependymoma

Ganglioglioma 

A

Pilocytic astrocytoma - A pilocytic astrocytoma is most commonly found in the cerebellum. They can also occur near the brainstem, in the cerebrum, near the optic nerve, or in the hypothalamic region of the brain.

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257
Q

Most sensitive for diagnosis of HIE on MRI in a neonate in the first 24hrs of life (repeat)

ADC

T2

DWI

Spectroscopy

A

DWI

HYPOXIC ISCHAEMIC ENCEPHALOPATHY
DWI is the first to become positive
Diffuse oedema with effacement of the CSF-containing spaces
Decreased cortical grey matter attenuation with a loss of normal grey-white differentiation
Decreased bilateral basal ganglia attenuation

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258
Q

Wilms - spontaneous regression can be seen in infants with metastatic disease t/f

A

TRUE

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259
Q

Normal pulmonary flow in kid - ?TOF or coarctation

A

coarctation

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260
Q

Which of the following findings on a 20 week scan would you be MOST likely to perform amniocentesis for?

Choroid plexus cyst measuring 6mm

Lateral ventricles measuring 14mm

Renal pelvis measuring 5-10mm

A

Lateral ventricles measuring 14mm should be <7mm AHW neonate <3mm

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261
Q

Which placental abnormality is LEAST likely to be associated with complications

Bilobed

Succenturiate lobe

Circumvallate

Placenta praevia

Membranacea

Velamentous cord insertion

A

ANSWER: Succenturiate lobe
- Increased risk of type II vasa previa
- Increased incidence of PHH from RPOC

Bilobed
- Velamentous cord insertion
- Increased incidence of type II vasa previa
- May increase PPH risk due to RPOC

Circumvallate
- Higher incidence of placental abruption
- Increased risk of IUGR

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262
Q

20 year old G1P0 presents for 20 week scan. US shows mass at the cord/foetal abdomen junction. The cord inserts to the side of the mass. Most likely cause?

Cord AVM

Gastroschisis

Omphalocele

Pseudoomphalocele

Physiological herniation

A

Gastroschisis

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263
Q

Large multilocular cystic mass occupying most of the pelvis, most likely diagnosis?

Mucinous cystadenoma

Serous cystadenoma

Dermoid

Brenner tumour

A

Mucinous cystadenoma

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264
Q

Haemorrhagic appearing 5.6cm ovarian cyst in a young female. Appropriate follow-up?

Follow up US in 4 weeks

Follow up US in 6 weeks

No follow up required

Gynaecological referral

MRI

A

Follow up US in 6 weeks

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265
Q

DCIS common appearance

On ultrasound, hypoechoic and hypervascular

A cluster of indeterminate microcalcifications on MMG

Mass on MRI

Architectural distortion on MMG

A

A cluster of indeterminate microcalcifications on MMG

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266
Q

Regarding papillary breast cancer

Mixed cystic cut surface on gross specimen

Spiculated margins on imaging

A

Mixed cystic cut surface on gross specimen

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267
Q

Radial scar diagnosed following biopsy. Most appropriate course of action?

Return to routine screening

Repeat mammo in 6 months

Hookwire and surgical biopsy

Hookwire, WLE and sentinel node biopsy

Mastectomy

A

Hookwire and surgical biopsy

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268
Q

Phyllodes tumour diagnosed on biopsy. Most appropriate course of action?

Return to routine screening

Repeat mammo in 6 months

Hookwire and surgical biopsy/simple excision

Hookwire and WLE

Mastectomy + SLNBx

A

Hookwire and WLE

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269
Q

Hypoechoic mass on ultrasound and well circumscribed on mammogram

Invasive ductal cancer

Invasive lobular cancer

Mucinous

Phylloides

DCIS

A

Phylloides

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270
Q

Which does NOT present as a spiculated mass on mammography?

Tubular carcinoma

Invasive ductal carcinoma

Medullary carcinoma

Invasive lobular carcinoma

Fat necrosis

A

Medullary carcinoma

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271
Q

Stellate lesion with long spicules without a central mass

Radial scar

Invasive ductal carcinoma

A

Radial scar

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272
Q

Least associated with BRCA1

Colorectal carcinoma

Pancreatic carcinoma

Ovarian carcinoma

Male breast carcinoma

Prostate carcinoma

A

Male breast carcinoma

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273
Q

Why is Pagets disease of the nipple occult on mammography (repeat)

A

a. DCIS cells spread via the lactiferous ducts to the nipple

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274
Q

MEN syndrome + calcified nodules with bone scan uptake

A

Metastatic calcification in the lungs

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275
Q

Which does NOT occur in pseudohypoparathyroidism

Dentate nucleus calcification

Flask deformity of long bones

Coned epiphyses

Abnormal dentition

?short 4th metacarpal

Normal calcium

A

Normal calcium

Pseudohypoparathyroidism
- Short stature
- Brachydactyly
- Short metacarpals
- Short metetarsals
- Soft tissue calcification
- Exostoses: short metapyseal or more central and perpendicular to long axis of a bone
- Broad bones with coned epiphyses

CNS
- Basal ganglia calcification
- Sclerochoroidal calcification
- Deep white matter calcification

Clinical presentation:
- Hypocalcaemia and tetany
- Short stature
- Developmental delay

Lead GNOME - causes of erlyenmeyer flask deformity
- Lead: lead poisoning
- G: Gaucher disease
- N: Niemann-Pick disease
- O: osteopetrosis, osteochondromatosis
- M: metaphyseal dysplasia (Pyle disease) and craniometaphyseal dysplasia
- E: ‘ematological, e.g. thalassaemia

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276
Q

How many x-rays is the equivalent of a PET/CT, with a low dose CT

700

1500

2000

A

700

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277
Q

Long question about a research study, if TP=a, FP=b, TN=c, FN=d, how to calculate prevalence in their study population (repeat)

a/b+d

a/a+c

b/a+c

b/c+d

a+d/a+b+c+d

A

a+d/a+b+c+d

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278
Q

Most often proposed mechanism for NSF (repeat):

Free gadolinium gets into tissues and incites fibrotic response

Free Gd chelate gets into soft tissues and incites fibrotic reaction

Albumin bound Gd gets into tissues

Some other combinations of chelated and otherwise bound Gd

A

Free gadolinium gets into tissues and incites fibrotic response

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279
Q

Increase the signal to noise ratio on MRI

Reduce voxel size

Increase field of view

Decrease number of excitations

A

Increase field of view

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280
Q

Inversion injury of the ankle. What is the most likely ligament involved?

Anterior talofibular ligament

Posterior talofibular

Deltoid ligament

Spring ligament

A

Anterior talofibular ligament

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281
Q

A patient has erythema/eczema of the nipple and a normal mammogram and ultrasound. What is the most appropriate next management?

Referral to a breast surgeon

Referral to a dermatologist

Repeat imaging in 3-6 months

MRI with contrast

A

Referral to a breast surgeon
MRI with contrast

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282
Q

Right lower quadrant pain USS demonstrates blind ending tubular structure with echogenic focus

Appendicitis

Haemorhagic corpus luteum

A

Appendicitis

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283
Q

What is the most likely appearance of a radial scar on mammogram?

Ill defined stellate mass

Architectural distortion

Amorphous calcifications

A

Architectural distortion

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284
Q

A 40 year old female has a low density pancreatic lesion. What is the most likely diagnosis?

Mucinous cystadenoma

IPMN

Serous cystadenoma

A

Mucinous cystadenoma

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285
Q

A middle aged patient has a barium swallow. It demonstrates a posterior outpouching at C5/6. What is the most likely diagnosis?

Zenker diverticulum

Cricopharyngeus

Epiphrenic diverticulum

A

Zenker diverticulum

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286
Q

 A patient has a barium follow through study. There is a narrowing at D2 secondary to external mass effect. What is the most likely diagnosis?

Annular pancreas

Pancreas divisum

Pancreatic atrophy

A

Annular pancreas

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287
Q

 PET scan is commonly used to image patients with lymphoma. Which type of lymphoma is least likely to be avid on PET scan?

a. Mycosis fungoides

b. Follicular lymphoma

c. Diffuse large B cell lymphoma

A

a. Mycosis fungoides

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288
Q

What is phaeochromocytoma least likely to be associated with?

VHL

Tuberous sclerosis

NF1

MEN?

A

Tuberous sclerosis – extra-adrenal paragangliomas

MEN - if MEN1 then this is true

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289
Q

A patient has an ankle injury where there is disruption of the ankle syndesmosis and a fibula fracture 5cm proximal to the ankle joint. What is the most likely injury?

Weber A

Weber B

Weber C

Maisonneuve fracture

A

Weber C

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290
Q

Which is the least likely cause of intussusception in a 2 year old?

Crohn disease

Henoch-Schonlein purpure

Lymphoma

Intraluminal lipoma

Meckel’s diverticulum

A

Crohn disease

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291
Q

Which of the following cannot be excluded on ultrasound?

AVN of the hip

Septic arthritis

Transient synovitis

A

AVN of the hip

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292
Q

 A 12 year old boy presents with a 3 month history of knee pain with a normal xray. What is the next investigation?

Hip x-ray

Knee MRI

Bone scan

A

Hip x-ray

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293
Q

Which is least likely to give endplate signal changes with are low on T1 and high on T2?

Modic type II

Spondylodiscitis

Tuberculosis

Disc herniation

Ankylosing spondylitis

A

Modic type II

Modic changes
1 - oedema and inflammation
T1 low, T2 high

2 - conversion into yellow fat
T1 high, T2 iso - high

3 - subchondral bony sclerosis
T1 low, T2 low

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294
Q

Which is the most likely right atrial lesion in a young child?

Atrial myxoma

Rhabdomyoma

A

Rhabdomyoma

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295
Q

What is the most common orbital lesion in a child?

Cavernous haemangioma

Retinoblastoma

Lymphoma

Melanoma

Coats disease

A

Retinoblastoma - one out of every 16,000–18,000 live births in the global population

Coats disease is a rare eye disorder involving abnormal development of blood vessels in the retina. Located in the back of the eye, the retina sends light images to the brain and is essential to eyesight. In people with Coats disease, retinal capillaries break open and leak fluid into the back of the eye.

 Most pediatric orbital tumors are benign; developmental cysts comprise half of orbital cases, with capillary hemangioma being the second most common orbital tumor. The most common orbital malignancy is rhabdomyosarcoma. The most common intraocular malignant lesion is retinoblastoma.

Cavernous hemangiomas are usually encountered in the orbit as primary tumors in adults. Patients with orbital cavernous hemangiomas typically present in the fourth and fifth decade of life. Lesions are rare in childhood. On the other hand, capillary hemangioma is the most common benign orbital tumor in children.

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296
Q

 A man has a headache a few days following an all-night party. CT demonstrates slight loss of grey-white matter differentiation in the left fronto-parietal region. LP is negative for RBCs and bilirubin. What is the most likely cause?

Ischaemia due to venous thrombosis

Encephalitis

Subarachnoid haemorrhage secondary to ruptured berry aneurysm

A

Ischaemia due to venous thrombosis

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297
Q

 Which is true regarding tuberculosis?

Calcified cavitating lesion in primary tuberculosis

Lymphadenopathy is more associated with secondary tuberculosis

Pleural effusion is more associated with primary tuberculosis

A

Pleural effusion is more associated with primary tuberculosis

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298
Q

A cholangiocarcinoma involves the primary confluence and extends to the left secondary confluence. What is the stage as per the Bismuth-Corlette criteria?

1

2

3a

3b

4

A

3b

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299
Q

Which is not a hamartomatous polyp syndrome?

Gardner syndrome

Peutz-Jegher syndrome

Cowden syndrome

Cronkite-Canada syndrome

A

Gardner syndrome

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300
Q

 Which liver injury is most likely to be caused by an overdose of analgesia?

Hepatocellular necrosis

Hepatitis

Cholestasis

A

Hepatocellular necrosis

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301
Q

 Which is not a risk factor/cause of pre-eclampsia?

Materal diabetes mellitus

Maternal pre-existing glomerulonephritis

Anti-phospholipid syndrome

?Liver disease on previous recall

A

?Liver disease on previous recall

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302
Q

A first trimester ultrasound demonstrates a twin peak sign. Which is most correct?

There are two separate placentas - dichorionic

There is a risk of twin-twin transfusion

Diamniotic, monochorionic

Monoamniotic, monochorionic

Dizygotic, monochorionic

A

There are two separate placentas - dichorionic

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303
Q

A patient has an enhancing, vascular mass in the epididymis. What is the most likely diagnosis?

Adenomatoid tumour

Lipoma

Teratoma

Epididymal cyst

A

Adenomatoid tumour

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304
Q

Which is the most likely pure germ cell tumour to be found in an elderly patient?

Spermatocytic seminoma

Embryonal cell carcinoma

Teratoma

A

Spermatocytic seminoma

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305
Q

BPH arises in the peripheral zone T/F

A

F

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306
Q

 A patient with an EVAR has a contrast filling the aneurysmal sac supplied by a lumbar artery. Which type of endoleak is this?

Type 1

Type 2

Type 3

Type 4

Type 5

A

Type 2

Type 1 - leak at graft attachment site

Type 2 - aneurysm sac filling via branch vessel

Type 3 - leak through a defect in the graft

Type 4 - leak through graft fabric as a result of graft porosity

Type 5 - continued expansion of the aneurysm sac without demonstrable leak on imaging

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307
Q

 Which is the best radiological finding for the detection of bowel trauma?

Bowel wall thickening

Mucosal hyperenhancement and mural oedema

Mesenteric congestion

Free fluid

A

Free fluid

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308
Q

Which is most correct regarding sedation in an elderly patient?

250mcg of fentanyl should be the a maximum dose

5mg of midazolam is an appropriate starting dose

There is a prolonged half life of midazolam in elderly patients

The most common side effect of midazolam is hypotension

A

There is a prolonged half life of midazolam in elderly patients -

Plasma half-life was approximately two-fold higher in the elderly.

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309
Q

Which is least associated with von Hippel Lindau?

Phaeochromocytomas

Haemangioblastomas

Pancreatic cysts

Renal cell carcinoma

A

Phaeochromocytomas -30%

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310
Q

A 30 year old man has a soft tissue mass which has high T1 fat sat signal. What is the most likely diagnosis?

Melanoma

Lipoma

Haemangioma

A

Melanoma

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311
Q

 A patient has high density military nodules throughout the lungs with a ‘black pleura’ sign. What is the most likely diagnosis?

Alveolar microlithiasis

Hypersensitivity pneumonitis

Metastatic pulmonary calcification

A

Alveolar microlithiasis

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312
Q

An elderly male presents with painless hematuria. What is the best sequence to show tumour invasion?

T2

T1 with fat sat

T1 without fat sat

DWI

A

T2

Slightly hyperintense compared to muscle, useful in determining the low signal muscle layer and its discontinuity when muscle wall invasion

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313
Q

A 3 year old patient presents with ataxia. Imaging shows a posterior fossa tumour with a low density enhancing mass in the vermis. What is the most likely diagnosis?

Hemangioblastoma

Metastataic neuroblastoma

Medulloblastoma

Ependymoma

Fibrillary astrocytoma

A

Medulloblastoma

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314
Q

What is the most common appearance of lobular carcinoma on mammogram?

Architectural distortion

Microlobulated mass

Well- defined mass

A

Architectural distortion

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315
Q

Lucent, well-defined lesion in S1 in young adult patient. ( No other feature mentioned)

Chordoma

ABC

Giant cell tumour

Metastasis

A

ABC

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316
Q

Best way for local staging of DCIS

Mammo

Mammo + US

Contrast enhanced MRI

? open biopsy

A

Contrast enhanced MRI

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317
Q

A patient has left superior cerebellar and left parietal infarct after stenting the extracrainal left ICA. What is the most likely explanation?

Persistent hypoglossal artery

Persistent trigeminal artery

Fetal origin of PCOMs

A

Persistent hypoglossal artery

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318
Q

 A 37 yr old is undergoing IVF treatment. She has bilateral ovarian cysts and extensive ascites. What is the most likely diagnosis?

Theca lutein cysts

Normal ovarian cysts

Ovarian hyperstimulation

A

Ovarian hyperstimulation

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319
Q

Which is not associated with an ACL tear?

Medial meniscus injury

Lateral meniscus injury

Anterior medial femoral (?)

Segond fracture

MCL tear

A

Anterior medial femoral (?)

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320
Q

Which is (not) a consequence of raised intracranial pressure?

Diffuse axonal injury

PCA infarction

ACA infarction

Duret haemorrhage

Kernohan’s notch

A

Diffuse axonal injury

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321
Q

Which is most correct regarding small bowel barium studies?

Thickening of the jejunal folds is coeliac

Nodular thickening of the jejunal folds in Whipples

A

Nodular thickening of the jejunal folds in Whipples

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322
Q

Cystic ovarian lesion, 10cm (not sure), unilateral, most likely:

Serous cystadenoma

Mucinous cystadenoma

A

Mucinous cystadenoma

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323
Q

Regarding melorrheostosis - which is not a feature?

Contractures

Thickened irregular bone cortex

Muscle atrophy

Scleroderma skin changes

A

ALL FEATURES

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324
Q

60 cyst ill defined, non expansile, adjacent to root of tooth, no tooth and no expansion no nonerupted teeth

Metastases

Ameloblastoma

Dentigerous cyst

Fibrous dysplasia

Odontoma

A

Metastases

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325
Q

34 male ataxia, right cerebellar low density striated mass

Cowden

Basal cell naevus

Encephalocraniocutaneous lipomatosis

A

Cowden

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326
Q

An older male patient has a mass encasing the kidney and adrenal gland, with Housfield density between -60 and +60 units. What is the most likely diagnosis?

A

Myxoid liposarcoma

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327
Q

A woman has a 15mm well defined breast mass. What is the most likely diagnosis?

A

Fibroadenoma or phyllodes

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328
Q

t/f midline sagittal best prenatal assessment of cleft lip?

A

false

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329
Q

Which is most correct regarding meningioma?

En plaque

Expansion of sella

Destruction of bone

Intense contrast enhancement

A

Intense contrast enhancement

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330
Q

4cm well circumscribed hypodense mass in the pancreas with peripheral calcification. Most likely:

Mucinous cystadenoma

Serous cystadenoma

IPMN

SPEN

A

Mucinous cystadenoma

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331
Q

Which is the best investigation for a thyroid lesion?

Iodine 131 scan

Tc99 Pertechtenate scan

A

Tc99 Pertechtenate scan

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332
Q

A jaundiced woman has a normal liver ultrasound and normal bile ducts. What is the most likely diagnosis?

Cholestasis

Fatty liver

NASH

Hepatitis

A

Cholestasis

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333
Q

Lung biopsy of a lesion in the posterior right mid lung is complicated by perilesional haemorrhage and haemoptysis. What is the next appropriate step?

Right side down

Left side down

Supine

Prone

Head up

A

Right side down

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334
Q

On CXR, there is a structure paralleling right heart border. What is the most likely diagnosis?

A

PAPVR

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335
Q

 Which liver lesion is least likely to have a central scar

Fibrolamellar HCC

HCC

FNH

Adenoma

Haemangioma

A

Adenoma

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336
Q

What is most associated with thyroid eye disease?

Pseudotumour

Graves disease

Hashimotos

Thyroiditis

A

Graves disease

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337
Q

Which is least likely to be associated with azygous continuation of the IVC?

Dextrocardia

Polysplenia

Gonadal veins draining into the ipsilateral renal veins

Hepatic veins draining into the IVC?

None of the above

A

Hepatic veins draining into the IVC?

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338
Q

A thyroid biopsy demonstrates medullary carcinoma. What is the next most appropriate investigation?

DMSA

DTPA

MAG-3

I-131

Tc99m-Pertechnetate

A

DMSA

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339
Q

A woman has intense pain in her knee after she walks her dog. There is intense oedema in the medial femoral condyle. What is the most likely diagnosis?

Radial tear medial meniscus

Medial ligament tear

Chondral defect - SONK

Loose body

Dog bite

A

Chondral defect - SONK

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340
Q

 A young male patient has a renal lesion which is high T1, low T2, and intensively enhancing. What is the most likely diagnosis?

AML

Proteinaceous cyst

Haemorrhagic cyst

Lymphoma

Clear cell carcinoma

A

Clear cell carcinoma - actually papillary

MRI is not only excellent at imaging the kidneys and locally staging tumours, but is also able to suggest the likely histology, on the grounds of T2 differences.

T1: often heterogeneous due to necrosis, haemorrhage, and solid components

T2: appearances depend on histology 6
clear cell RCC: hyperintense
papillary RCC: hypointense

T1 C+ (Gd): often shows prompt arterial enhancement

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341
Q

A 3 week old neonate has jaundice, hypoplastic kidneys and an H shaped vertebra. The liver appears normal on ultrasound and the gallbladder is small.

What is the most likely diagnosis?

Caroli disease

Biliary atresia

Allagile syndrome

Bile plug syndrome

A

Allagile syndrome

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342
Q

20yo acetabular fracture, most likely injury

Bladder injury

Pelvic haematoma

Sacral injury

A

Pelvic haematoma

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343
Q

Which is true regarding fibromuscular dysplasia?

Most common cause of hypertension in children and young adults

Does not respond well to angioplasty

Only affects media

A

none

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344
Q

Which is most useful for differentiating between a ranula and lymphangioma?

Extension into paraphyrngeal space

Extension into retropharyngeal space

Extension into infrahyoid tissues

A

Extension into infrahyoid tissues

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345
Q

A hysteroscopy study for infertility shows two holes in the cervix. Which is the most likely diagnosis?

Bicornuate

Didelphys

Unicornuate

Septate

A

Bicornuate - more common

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346
Q

What is the best position to examine the subscapularis muscle on ultrasound?

External rotation with the elbow flexed

Internal rotation with the arm touching the opposite shoulder

External rotation arm behind the back

Abducted arm

A

External rotation with the elbow flexed

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347
Q

Child with previous history of bacterial meningitis, now with unilateral sensorineural hearing loss. What is the most likely diagnosis?

Otosclerosis

Labyrinthitis ossificans

A

Labyrinthitis ossificans

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348
Q

 Which is incorrect regarding DVTs? (March 2016)

Most DVTs start in the soleal ‘sinusoids’

Most below knee DVTs will propagate to the surface without intervention

In ambulatory patients, only 5-10% of DVTs will result in PEs

Most patients with DVTs in the community are asymptomatic

A

Most below knee DVTs will propagate to the surface without intervention

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349
Q

Which is the most common infection associated with cystic fibrosis?

ABPA

Klebisiella

Pseudomonas

A

Pseudomonas

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350
Q

Rugby player kicked in scrotum with pain. Ultrasound shows intact tunica with heterogenous echogenic testes.

Rupture

Haematoma

Fracture

Abscess

Torsion

A

Haematoma

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351
Q

24 y.o. Obese male with retroareolar pain. Ultrasound shows hypoechoic mass under areola with lobulated posterior margins. Most likely option:

Gynaecomastia

Pseudo-gynaecomastia

Male breast cancer

Lipoma

A

Gynaecomastia

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352
Q

Which association is least likely:

Methotrexate and pneumatocoele

Phenytoin and eosinophilic lung disease

Amiodarone and interstitial infiltrate

Cyclosporine and pulmonary mass – due to fungal pneumonia

Sulfasalazine and eosinophilic lung disease

A

Methotrexate and pneumatocoele

Methotrexate

inflammatory: fibrotic disease

superimposed pulmonary infection: from immunosuppression

pulmonary lymphoproliferative disease: from immunosuppression

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353
Q

Regarding fibroadenoma which is FALSE.

Can contain invasive foci

Commonly involutes

Smooth mass on mammography

Commonly presents in <30

Common in post-menopausal women

A

Common in post-menopausal women

Fibroadenomas constituted 20% (39 of 195) of the benign masses and 12% (39 of 339) of all breast masses in postmenopausal women.

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354
Q

Regarding radial scar which is true?

Requires further management.

Should be re-biopsied

Has short spicules.

Palpable as a clinical mass.

The central fat is often replaced by soft tissue

A

Requires further management.

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355
Q

45 m with neck lump which extends through thyrohyoid membrane and had an air fluid level and thin rim.

Laryngocoele

Epidermoid cyst

Abscess

Thyroglossal duct cyst

Lymphatic malformation

A

Laryngocoele

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356
Q

1.5cm well defined breast lesion in a 50yo F - what is least likely

Mucinous cancer

High grade IDC

Fibroadenoma

Simple cyst

Sebaceous cyst

A

High grade IDC – typically spiculated

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357
Q

Most likely appearance of medullary ca

Well defined mass

Spiculated mass

Mass with cystic spaces

Fine branching calcs

Thick calcs

A

Well defined mass

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358
Q

Most likely to involve epiphyses?

Osteoid osteoma

ABC

Clear cell chondrosarcoma.

Chondromyxoid fibroma.

Fibrosarcoma.

A

Clear cell chondrosarcoma.

Epiphyseal, unlike the conventional chondrosarcoma which is usually metaphyseal-diaphyseal

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359
Q

Least likely to be associated with RCC.

VHL

CRF on renal failure

NF1

Obesity

Smoking.

A

NF1

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360
Q

Least likely to affect basal ganglia.

Amyloid angiopathy.

Hypertension.

Ischaemic encephalopathy.

A

Amyloid angiopathy.

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361
Q

34yr female known twins presents for ultrasound. Twin peak sign. Which is most likely?

Monochoriotic diamniotic

Monochoriotic monoamniotic

There are two placentas

The twins are at risk of twin twin transfusion

A

There are two placentas

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362
Q

Neonate in cyanosis. Echocardiogram shows right atrial lesion. What is most likely

Haemangioma

Fibroma

Rhabdomyoma

Atrial myxoma

Lipoma

A

Rhabdomyoma – monitor and they go away, associated with TS

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363
Q

45yr female. Hypodense lesion in Pancreas with enhancing nodule. Peripheral calcification. Which is most likely?

Serous microcystic

Serous macrocystic

Mucinous cystadenoma

IPMN

SPEN

A

Mucinous cystadenoma

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364
Q

 What is least like to present as a cystic lung lesion?

Mycoplasma pneumonia

Pulmonary lymphoma

Neurofibromatosis

Lymphoid granulomas

Tuberous sclerosis

A

Mycoplasma pneumonia

Pulmonary manifestations of NF-1, which usually include bilateral basal reticulations and apical bullae and cysts, are reported in 10-20% of adult patients.

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365
Q

40yr female. Right angle of jaw lesion. Painless non smoker. On ultrasound mixed solid and cystic change that involves part of the parotid gland and 2 other lesions in the adjacent soft tissue. What is most likely?

Lymph nodes

Sjogrens

Warthins tumour

Benign mixed lesion - oncogenic simian virus (SV40)

Lymphoepithelial cysts

A

Warthins tumour

They may be bilateral or multifocal in up to 20% of cases and are the most common neoplastic cause of multiple solid parotid masses.

Associated with smoking

Painless enlargement

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366
Q

50 yo male non-smoker no history of occupational exposure. CT Chest shows a 5mm non-calcified nodule in LUL. What does the Fleischner society guidelines recommend?

No follow up

Follow up in 12 months then stop if no change

Initial follow up in 6-12 months then in 18-24 months, then stop if no change

Initial follow up in 3-6 months then in 9-12 months and 18-24 months, then stop if no change

Follow up in 3, 9 and 12 months with dynamic post-contrast CT Chest and PET/CT +/- biopsy

A

No follow up

Low risk = no routine follow up required

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367
Q

47yo male (smoking history not specified) with persistent cough. Ill-defined non-calcified 8mm nodule in RUL. Which is MOST correct:

PET/CT to assess for malignancy

CT-guided FNA to assess for malignancy

Enhancement by greater than 35HU post IV contrast is associated with greater than 97% risk of malignancy

Likely benign (<2% risk of malignancy) if the lesion has remained stable in the last 30 months

Follow up in 12 months and 24 months

A

Follow up in 12 months and 24 months

F/U 6-12, then every 2 yrs for 5 if persistent – if subsolid, if solid, 12 mo then 24mo

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368
Q

10y boy with fever and cough. CXR shows bilateral lower zone opacities and linear atelectasis. Which is most likely cause (REPEAT):

Chlamydia pneumonia

Mycoplasma pneumonia

Pneumocystis jirovecii pneumonia

Staphylococcus pneumonia

Tuberculosis

A

Mycoplasma pneumonia

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369
Q

88y woman with dementia in nursing home, found collapsed. CT Brain shows a 2cm elliptical highattenuation lesion superficially in the right middle frontal gyrus. What is the MOST likely cause?

Hypertensive hemorrhage

Berry aneurysm

Hemorrhagic neoplasm

Amyloid angiopathy

Trauma

A

Amyloid angiopathy

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370
Q

What is most likely mammographic appearance of papilloma (REPEAT)

Spiculated mass

Well defined mass with microlobulated contours

Amorphous calcification

Dense linear calcs

Fine linear branching calcs

A

Well defined mass with microlobulated contours

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371
Q

With regards to osteomyelitis, which is true ?

Gadolinium helps to make the endplate changes more conspicuous on T1WI

Staph aureus is the most common cause in a 75 year old

MRI appearances can mimic modic type 1 changes

The presence of a paraspinal mass suggests malignancy.

A

Gadolinium helps to make the endplate changes more conspicuous on T1WI

Staph aureus is the most common cause in a 75 year old

MRI appearances can mimic modic type 1 changes

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372
Q

 In screening mammography, granular microcalcifications of variable size and shape is suggestive of?

DCIS

LCIS

Papilloma

Milk of calcium

Oil cyst

A

DCIS - pleomorphic

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373
Q

Patient with a chance fracture of T12. Which is the most common associated injury ?

Renal laceration

Splenic laceration

Duodenal contusion

Mediastinal haematoma

Rib fracture.

A

Duodenal contusion

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374
Q

65 year old male with back pain and a T8 sclerotic lesion on xray. Most appropriate next management?

No further investigation required.

Bone scan

MRI.

CT.

Skeletal survey.

A

CT.

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375
Q

Patient with acute pulmonary oedema. Normal heart size. Which is Least likely?

Massive PE.

AMI.

Chronic pericarditis.

Mediastinal fibrosis.

Neurogenic cause.

A

Massive PE.

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376
Q

Pseudomyxoma peritoneii is most common in?

Appendiceal mucocoele

Mucinous cyst adenocarcinoma of the ovary.

Mucinous carcinoma of the appendix.

A

Mucinous carcinoma of the appendix.

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377
Q

Mr. John’s is supposed to get a PICC line. Mr Smith is supposed to get a CT Scan. Mr. John’s details are attached to Mr. Smith’s request form and he is sent for his PICC line. What is the best question to ask?

What is your name.

What is your MRN

What is your date of birth.

What is your understanding of what procedure you are getting today?

A

What is your understanding of what procedure you are getting today?

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378
Q

6 year old girl with clinodactyly of the 5th finger with features of bone and soft tissue overgrowth. What is most likely?

NF1

Macrodystrophia

A

Macrodystrophia lipomatosa

Clinodactyly – radial angulation at an interphalangeal joint in the radio-ulnar or palmar planes

Typically affects the 5th finger

Varied aetiology, ranging from congenital to acquired

Aneuploidic syndromic
- Down syndrome
- Klinefelter syndrome
- Trisomy 18
- Turner syndrome

Non-aneuploidic syndromic
- Cornelia de Lange syndrome
- Feingold syndrome
- Roberts syndrome
- Russell-Silver syndrome
- Fanconi anaemia

Non-syndromic
- Macrodystrophia lipomatosa
- Brachydactylyl type A3

379
Q

Which of the following is NOT a component of the Wells criteria?

Haemoptysis

HR greater than 100

Oral contraceptive pill

Previous DVT/PE

No other diagnosis more likely than PE

A

Oral contraceptive pill

380
Q

A variant of a woman presents at 32 weeks with possible intracranial calcs on the Trans abdominal study. What do you do?

If the baby is in a cephalic presentation do a TV study.

TORCH infections do not cross the placenta in the 3rd trimester and are therefore excluded

If there is also hepatic calcification this is seen in DiGeorge syndrome

If there has been prior chromosomal testing this is not necessary.

A

If the baby is in a cephalic presentation do a TV study.

381
Q

A lady has mammographic biopsy result of LCIS with adjacent calcification. What is the cause of the calcification?

Calcification is an incidental finding.

Calcifications are related to necrotic material in ducts.

Calcification is due to periductal exudate/inflammation.

A

Calcification is an incidental finding.

382
Q

Which is an X linked inherited disorder?

Adrenoleukodystrophy

Alexander disease

Hurler

Leigh

Tay Sachs

A

Adrenoleukodystrophy

Adrenoleukodystrophy
- Characterised by a lack of oxidation of very long chain fatty acids (VLCFAs) that results in severe inflammatory demyelination typically of the periventricular deep white matter with posterior-predominant pattern and early involvement of the splenium of the corpus callosum and parietal white matter changes.
- There tends to be cortical and subcortical U-fibre sparing.

Alexander disease
- There are three clinical forms: infantile/childhood-onset (most common), juvenile onset and adult onset (AOAD).
- Mutation in the coding region, mapped to chromosome 17q21, of GFAP an astrocyte-specific intermediate filament protein.
- Macrocephaly is typically present, and other clinical features include progressive quadriparesis and intellectual failure.
- Most of the cases are sporadic. However, familial disease has also been reported.
- The disease begins in the frontal region and extends posteriorly.

Hurler syndrome
- One of the mucopolysaccharidoses.
- It manifests in the first years of life with intellectual disability, corneal clouding, deafness, and cardiac disease.
- It carries an autosomal recessive inheritance.
- Hydrocephalus, J-shaped sella, cord compression at the craniovertebral junction, shortening and widening of long bones, pointing of proximal metacarpals, widening of anterior ribs, thoracolumbar kyphosis, anterior inferior vertebral body beaking.

Leigh syndrome
- Leigh syndrome, also known as subacute necrotising encephalomyelopathy (SNEM), is a mitochondrial disorder with progressive neurodegeneration that invariably leads to death, usually in childhood.

Tay Sachs
- Tay-Sachs disease is a hereditary neurodegenerative disorder resulting from excess storage of GM2 ganglioside within the lysosomes of cells.
- MRI is superior to CT in delineating deep white matter demyelination.
- Thalami may show changes consistent with calcification, best seen on T2* weighted sequences.
- No abnormal contrast enhancement is described.

383
Q

Most common presentation of tracheomalacia?

Always has expiratory stridor

The trachea is extremely dilated.

There are concentric tracheal rings.

A

The trachea is extremely dilated. - Plain inspiratory radiographs are usually normal or may demonstrate a dilated trachea.

384
Q

Regarding male breast cancer, which is most true?

40-60 y.o.

Most common type is invasive ductal cancer.

Worse prognosis than female for same subtype and age.

Painful subareolar mass. 

A

Most common type is invasive ductal cancer.

85-90%

385
Q

Regarding inverting papilloma. Most correct?

Association with SCC.

Arises from lateral pterygopalatine fossae.

When it gets large it causes posterior displacement of the posterior wall of the maxillary sinus.

Arises from bony nasal septum.

A

Association with SCC.

386
Q

70 y.o. Man with SVC syndrome from adenopathy obstructing the SVC with lung cancer. There is an avidly enhancing structure above the right hilum. What is most likely?

Dilated azygos vein.

Dilated pulmonary artery

Dilated pulmonary vein.

Bronchogenic cancer.

Hilar LN

A

Dilated azygos vein.

387
Q

US of the rotator cuffs for subscapularis?

External rotation with elbow flexed.

Abducted shoulder, and arm straight.

Arm across front, touching shoulder.

Arm behind back.

Neutral position.

A

External rotation with elbow flexed.

388
Q

Patient has chondrocalcinosis of the menisci and patellofemoral OA. What would other imaging show?

Pubic symphysis calcification.

MCP involvement.

1st MTP involvement.

A

Pubic symphysis calcification.

389
Q

Which is least likely regarding the thymus?

Thymoma is most common in adolescence.

Ectopic thymus tissue in the neck is a known variant.

The thymus decreases in size during stress.

The largest absolute size is at 10 - 15 years.

A

Thymoma is most common in adolescence. - The typical presentation is in the 5th to 6th decades, without gender predilection.

390
Q

Q67. There is focal dilatation of the distal CBD bulging at the duodenal wall. Which type of choledochocoele is it?

1

2

3

4

5

A

3

391
Q

Which is least likely to cause intussusception in a 2 year old?

Crohn’s disease

Meckel’s diverticulitis.

Lymphoma.

Gastroenteritis.

A

Crohn’s disease

392
Q

A 50 y.o. Male has abdominal pain. In the terminal ileum there is a long segment of bowel with a target sign appearance and proximal dilatation of the small bowel. What is most likely?

Intussusception.

Carcinoma

Lymphoma

Crohn’s

A

Crohn’s

393
Q

Hydatiform moles are most associated with?

Bilateral theca lutein cysts.

If there is extension into the veins then that means malignancy.

Lung mets from invasive mole are poorly responsive to chemotherapy.

A

Bilateral theca lutein cysts.

394
Q

4 week old with jaundice. There is a 8.5mm gallbladder and a hyperechoic triangular cord at the porta hepatis. What is most likely?

Biliary atresia

Alagille syndrome.

Neonatal hepatitis.

A

Biliary atresia

395
Q

 Osteomyelitis/discitis. Which is most correct?

MRI changes mimic MODIC 1

Gadolinium helps to identify endplate changes on T1.

Staph aureus is most common in 75 y.o.

Paraspinal mass suggest malignancy.

A

Staph aureus is most common in 75 y.o.

Most common of all, 80-90%

396
Q

In screening mammography, granular microcalcifications of variable size and shape. What is most likely?

DCIS.

LCIS.

Papilloma.

Milk of calcium.

Oil cyst.

A

DCIS

397
Q

Young child, physiological uptake is not seen in:

Thymus

Heart

Bone marrow

Colon.

Thyroid

A

?Maybe thyroid

398
Q

Cystic lesion deep to parotid extending to parapharyngeal space

1st branchial cleft cyst

2nd branchial cleft cyst

3rd branchial cleft cyst

Lymphangioma

A

1st branchial cleft cyst

399
Q

Which is not involved in Le Fort 3 fracture or tripod fracture.

Orbital floor

Zygomatic arch

Maxillary wall

Orbital roof.

A

Orbital roof.

Le Fort

Type 1
- Horizontal maxillary fracture, separating the teeth from the upper face
- Fracture line passes through the alvoelar ridge, lateral nose and inferior wall of the maxillary sinus

Type 2
- Pyramidal fracture, with teeth at the pyramidal base, and nasofrontal suture at its apex
- Fracture arch passes through the posterior alveolar ridge, lateral walls of maxillary sinuses, inferior orbital rim and nasal bone
- Uppermost fracture line can pass through the nasofrontal junction

Type 3
- Craniofacial disjunction
- Transverse fracture line passes through the nasofrontal suture, maxillo-frontal suture, orbital wall and zygomatic arch/zygomaticofrontal suture
- Risk of temporalis muscle impingement

400
Q

30 yo female presents with proximal dysphagia. What is most likely?

Zenker’s diverticulum

Cancer.

Barretts

Scleroderma.

A

Zenker’s diverticulum

Rarely found <40yo

401
Q

V/Q scan. Which is most correct?

Modified PIOPED can be reported as “normal” study.

Large perfusion defect with pleural defect is associated with high likelihood of PE.

Technegas given before perfusion

Technegas is given as 5x MAA

Pleural effusion…

A

Technegas given before perfusion

Used during the ventrilation phase, performed before the perfusion phase

402
Q

vSacral lesion with soft tissue mass. Which is NOT definitely associated?

GCT

Chondrosarcoma

Chordoma

Lymphoma

Ewings sarcoma.

A

Lymphoma – but not a great answer

403
Q

50yo female with chronic umbilical discharge. CT shows bladder roof wall thickening and cyst and discharge from umbilicus. Which is most likely?

Adenocarcinoma

SCC

TCC

A

Adenocarcinoma

404
Q

6 month old with macrocephaly and retardation. MRI shows cystic collection in posterior fossa. What other features are MOST supportive of a Blake’s Pouch cyst?

Hypoplastic vermis, enlarged 4th ventricle, hydrocephalus, no occipital dysplasia.

Normal vermis, normal 4th ventricle, hydrocephalus, no occipital dysplasia

Hypoplastic vermis, normal 4th ventricle, no hydrocephalus, no occipital dysplasia.

Normal vermis, enlarged 4th ventricle, hydrocephalus, no occipital dysplasia.

Normal vemis, normal 4th ventricle, hydrocephalus, occipital dysplasia

A

Normal vermis, enlarged 4th ventricle, hydrocephalus, no occipital dysplasia.

405
Q

Knee pain in adult. Which is LEAST likely to be injured in pivot shift injury?

ACL

PCL

MCL

Posterolateral tibial plateau

Lateral femoral condyle

A

PCL

406
Q

Which is NOT a recognized sacral lesion with soft tissue mass?

Chrondoblastoma

Ewings sarcoma

Chordoma

Lymphoma

GCT

A

Chrondoblastoma

407
Q

Mortons neuroma which is false?

Pain due to entrapment of a digital nerve.

As a hypoechoic, well defined lesion on ultrasound.

Bilateral in 10%

Between metatarsal shafts.

Usually occurs in middle aged women

A

Between metatarsal shafts.

408
Q

Liver MR with hepatocyte specific contrast agent in ~40 yo. Woman. Shows arterial hyperenhancement, isointensity in both PV and delayed phase 20 minutes later. Most likely?

FNH

Adenoma

Fibrolamellar HCC

Metastasis

Hemangioma

A

FNH

409
Q

Middle aged women with abdominal discomfort. Gastric fundus 1.5cm sessile mass at right angles to lumen. Which is most correct?

Stromal tumour

Lipoma

Lymphoma

Neurofibroma

A

Stromal tumour

410
Q

 Young boy with unilateral chest wall deformity. Small chest, absent pectoral muscles. Most likely?

Cleidocranial dysplasia.

Poland syndrome

NF 1

A

Poland syndrome

411
Q

MAG3 + Captopril scan is used to diagnose: rep

Renal artery stenosis

PUJ obstruction

Renal function

RCC

A

Renal artery stenosis

412
Q

Female patient in 3rd trimester has 3 days of painless PV bleeding. What is most likely?

Accreta

Abruption

Circummarginate

Praevia

Percreta.

A

Praevia

Low lying placenta – close to, or covering the internal cervical os

413
Q

45 y.o female patient with a 9cm pancreatic lesion with a mural nodule and peripheral calcifications. What is most likely?

Mucinous cystadenoma

IPMN

Serous cystadenoma

Solid-pseudo-papillary

A

Mucinous cystadenoma

414
Q

40 y.o. Man with a unilocular mandibular cyst with an enhancing mural nodule.

OKC

Amelloblastoma

Radicular cyst

Periapical cyst.

A

Amelloblastoma

415
Q

Lady with painless swelling of the neck. Ultrasound shows 3 solid/cystic lesions. One in the parotid, and 2 in the adjacent soft tissues. What is most likely?

Sjogrens

Warthins tumours

Lymphoma

Metastases

Lymphoepithelial cysts.

A

Warthins tumours

416
Q

60 year old with an intracranial calcified cyst found during work up for dementia. What is most likely?

Choroid plexus cyst

Neurenteric cyst.

Epidermoid cyst.

VIrchow robin’s spaces.

A

Choroid plexus cyst

417
Q

 A twin peak sign in pregnancy can occur in what?

Can occur in monozygotic dichorionic

Can occur in monozygotic monoaminotic

Associated with twin to twin transfusion syndrome

Can occur in dizygotic monochorionic pregnancy

. can occur in monozygotic diaminotic

A

Can occur in monozygotic dichorionic

418
Q

78 yo. Female has painless diplopia.Imaging demonstrates nodular thickening of the medial rectus and superior rectus in right eye. What is most likely?

Metastases.

Lymphoma

Grave’s disease

Orbital pseudotumour

Inflammation.

A

Lymphoma

Primary lymphoma of the orbit is one of the commonest orbital tumours and accounts for as much as half of all orbital malignancies. It is a B-cell non-Hodgkin lymphoma, and in most cases arises from mucosa-associated lymphoid tissue (MALT).

419
Q

Type of bladder injury that can be occult on CT:

Mucosal tear.

Intimal injury

Intraperitoneal rupture

Extraperitoneal rupture

A

Mucosal tear.

420
Q

What is least associated with annular pancreas? (I think underlying question has to do with GI associations in Downs).

Oesophageal atresia

Anal atresia

Congenital heart disease

Hypertrophic pyloric stenosis.

A

Hypertrophic pyloric stenosis. – T18 or Tuners

421
Q

 An old man has a fall, rib fractures and pneumothorax. What is most urgent indication for drain?

Air-fluid level.

Ipsilateral mediastinal shift

Eversion of the ipsilateral hemidiaphragm.

Visualisation of lateral pleural edge.

A

Eversion of the ipsilateral hemidiaphragm.

422
Q

CT chest in Acute chest pain patient radiation to back. Non contrast CT shows high density in the media. What is most likely?

Intramural hematoma.

Dissection

Aneurysm

Aortitis.

A

Intramural hematoma.

423
Q

 A lady has a 3mm proximal carotid ICA aneurysm. What is likely?

The aneurysm is at high risk of rupture and needs urgent neurosurgical review.

The aneurysm can compress structures and cause neurological compromise.

Monitor over next few months.

A

Monitor over next few months.

424
Q

With Haemophilia B what is most (? Least likely)?

Most presents at birth?

Secondary avascular necrosis occurs most commonly at hip.

Secondary osteoporosis occurs most commonly at knee.

A

Secondary osteoporosis occurs most commonly at knee.

425
Q

Neonatal renal ultrasound, which are not normal findings:

Cortical echogenicity equal to or greater than liver

Prominent hypoechoic pyramids

Prominent echogenic sinus

Junctional parenchymal defect at right upper pole

Fetal lobulations

A

Cortical echogenicity equal to or greater than liver

Tamm-Horsfall proteins, also known as uromodulin, may be a cause of echogenic renal pyramids in a neonate.

426
Q

Voltage gated potassium channel encephalitis affects which part of the brain:

Hippocampus

Habenula

Central tegmental tracts

Dorsolateral prefrontal cortex

Olfactory gyrus/cortex/groove

A

Hippocampus – amygdala without hippocampus

427
Q

Low T2 signal mass in the latissimus of a 33 year old male:

Desmoid

Elastofibroma

Other less correct sounding things

A

Desmoid - right age, right signal

428
Q

Biliary atresia, which is most suggestive:

Dilated intrahepatic ducts

Reduced vascularity at periphery

Debris in gallbladder

Cyst at porta hepatic

Dilated portal vein

A

Cyst at porta hepatic

hepatic ducts absent
absent gb
dilated ha

429
Q

Which is correct:

Vasogenic oedema has restricted diffusion

Around an abscess, the ADC is low

Intracellular methaemoglobin is low on DWI

Acute infarct is high on ADC

Arachnoid cyst is markedly hyperintense on DWI

A

Intracellular methaemoglobin is low on DWI

430
Q

TCC:

Renal pelvis more likely papillary type

Bladder more likely sessile type

Ureter more likely papillary type

A

Renal pelvis more likely papillary type

431
Q

Follow up for antenatal hydronephrosis, which is incorrect:

Dilated ureter implies obstruction

Renal pelvis thickening with reflux

Ectopic ureterocele implies duplex in female

Ultrasound at day two has a high false negative rate

A

Dilated ureter implies obstruction

432
Q

Cardiac myxoma false:

Uniform low T2 signal

Heterogeneous enhancement

Attached to septum

Can be pedunculated

Carney syndrome

A

Uniform low T2 signal -

Can be variable due to heterogeneity in tumour components; e.g. calcific components > low signal; myxomatous components > high signal

433
Q

Which is true:

Cardiac myxomas account for 50% of primary cardiac tumours

Cardiac metastasis less common than cardiac primary malignancy

A

Cardiac myxomas account for 50% of primary cardiac tumours

434
Q

Invasive lobular CA:

Well circumscribed

Typical non-mass like enhancement on MRI

Malignant microcalcifications

Local staging best by MRI

A

Local staging best by MRI

435
Q

Chronic recurrent multifocal osteomyelitis:

More than 5 lesions on bone scan

Typical lytic lesion at the epiphysis

Distal third of the clavicle

Tibial location is most common

A

Tibial location is most common

436
Q

IV contrast passes into the media of an artery in:

PAU

mural thrombus

IMH

Transsection

Aneurysm leak

A

PAU

437
Q

20 year old male with renal artery stenosis and infrarenal aortic stenosis:

Takayasu

Bechets

PAN

Kawasaki

FMD

A

Takayasu

438
Q

Bilateral painless lacrimal gland enlargement and unilateral preseptal swelling in a female:

Lymphoproliferative

Inflammatory

Thyroid eye disease

Metastasis

Erdheim-chester disease

A

Lymphoproliferative

439
Q

Angiodysplasia most common location:

Right colon mesenteric

Right colon antimesenteric

Left colon mesenteric

Left colon antimesenteric

Left colon mesenteric and antimesenteric

A

Right colon antimesenteric

440
Q

Crazy paving pattern, which is false:

PAP

Invasive mucinous adenocarcinoma

PCP

RB-ILD

Alveolar sarcoidosis

A

RB-ILD

441
Q

Renal artery stenosis:

10% FMD

15% cause of hypertension

High resistive index distal to site of stenosis

Elevated aortic ratio greater than 2.5cm/s

Acceleration time greater than 3s

A

Elevated aortic ratio greater than 2.5cm/s

442
Q

Ectopics, which is false:

Myometrial anterior thinning and vascularity in scar ectopic.

Interstitial ectopic has thinning of myometrium but sac is continuous with endometrial cavity

20% have pseudosac appearance

Interstitial ectopics can present later

A

Interstitial ectopic has thinning of myometrium but sac is continuous with endometrial cavity

443
Q

Hepatic Infantile hemangiomas associated with:

GLUT1 underexpressed

More than 5 skin hemangiomas

Calcification

Low T2 high T1

A

Calcification – occurs in 15%

444
Q

Low T2 low T1 Baker’s cyst in young male:

A

PVNS

445
Q

Erosive osteoarthritis:

DIP and PIP reasonably equally common

Synovitis

MCPJ

A

Synovitis

446
Q
  1. Chronic lymphadenitis most correct

Severe infection

Most likely in the inguinal region

Complicated by fistula

Painful masses

Can be generalised in systemic viral infection

A

Can be generalised in systemic viral infection – true

447
Q

Subacute thyroiditis (DeQuevins)

Gland grossly enlarged

Gland small and shrunk

Normal size

Slight enlargement

Gland nodular and enlarged

A

Slight enlargement

Sub-acute thyroiditis can either be granulomatous (De Quervain) or lymphocytic.

Granulomatous
- F>M, ages 40-50
- Probably triggered by viral infection
- ‘Unilaterally or bilaterally enlarged and firm’, ‘Is painful with variable enlargement of the gland’
- Radiopaedia ‘thyroid gland is mostly normal in size but can be enlarged or smaller in size’
- Usually have elevated T3 and T4 and low TSH
- Radioactive iodine uptake is diminished

Lymphocytic
- Usually middle aged females or in post-partum state
- Painless
- Thyroid appears normal side from possible mild symmetric enlargement
- Can present with hypertrhyoidism with most patients euthyroid by 1 year, can develop hypothyroidism
- D is favoured (mild enlargement)

448
Q

Which is correct;

PML at frontal lobe gyri

HSV1 encephalitis inferior temporal lobes

A

HSV1 encephalitis inferior temporal lobes

HSV1 typically leads to bilateral and asymmetric involvement of the limbic system, mesial temporal lobes, insular cortices and inferolateral frontal lobes. Basal ganglia typically spared.
- Robbins ‘inferomedial temporal lobes and orbital gyri of frontal lobes’ . Perivascular infiltrate with Cowdry A intranuclear viral inclusion bodies.

 PML relates to oligodendrocyte infection by the JC virus in immunosuppressed patients.
- Typically bilateral asymmetric supratentorial white matter and thalamic involvement.
- Subcortical frontal and parieto-occipital regions are common locations.

Both are correct, B maybe more specific

449
Q

Asbestos related disease incorrect

Pleural effusion

Mesothelioma be difficult to histologically distinguish from metastatic adenocarcinoma

No zonal predilection of plaques

Thickening involves visceral and parietal pleura

Associated with lung adenocarcinoma and SCC

A

No zonal predilection of plaques

450
Q

Ulcerative colitis most associated with

PSC

PBC

A

PSC

UC is associated with PSC, 7.5% of patients with UC have PS, 70% of those with PSC have IBD.

PSC affects both the intra and extra-hepatic ducts resulting in a beaded appearance. There is often a +ve p-ANCA. Increased risk of chronic pancreatitis, cholangiocarcinoma and HCC.

 PBC is mostly middle-aged females with other autoimmune disorders (Sjogrens in 70%, scleroderma in 5%). 95% of patients are AMA positive. Radiology can be normal as only small intra-hepatic ducts are affected

451
Q

AFP elevated in which testicular tumour

Seminoma

Teratoma

Embryonal

Endodermal sinus tumour

Choriocarcinoma

A

Endodermal sinus tumour (other name for yolk sac - yolk sac name not given)

452
Q

Pelvic inflammatory disease

Endometrium is oedematous

Gonorrhoea treated with curettage

Community acquired starts in uterus

Fusion of the Fallopian tubes

Infertility common in chronic

A

Infertility common in chronic (40% chance of 3 episodes of PID) 8% after the first episode to as high as 40% after three

Over time the infecting organisms can disappear leaving the sequelae of chronic follicular salpingitis which is where the tubal plicae adhere to each other and fuse in a scarring process.

PID is generally an ascending infection, often beginning in the vulva or vagina. This can then lead to endometritis, salpingitis and later infect contiguous structures (TOA). Gonococcus infection usually starts in the endocervical mucosa. Non-gonococcal infections following instrumentation more likely spread from the uterus upward through the lymphatics and venous channels rather than on the mucosal surface.

Causes include:
- Neisseria gonorrhoeae
- Chlamydia trachomatis
- Polymicrobial infections in up to 35%
- Rarer aetiologies include TB and actinomyces
- Can be sexually transmitted or relate to delivery, abortion or instrumentation.

453
Q

PID (?false)

Tubo ovarian abscess can be treated by antibiotics

Fallopian tubes become fused

Endometrium is oedematous

Community acquired disease originates in the uterus

Infertility common in chronic

A

Community acquired disease originates in the uterus FALSE

The infection generally ascends from the vagina or cervix (cervicitis) to the endometrium (endometritis), then to the fallopian tubes (salpingitis, hydrosalpinx, pyosalpinx), and then to and/or contiguous structures (oophoritis, tubo-ovarian abscess, peritonitis).

Research shows tubal scarring caused by PID can lead to tubal factor infertility (a condition in which the fallopian tubes are blocked or damaged) in between 8% (after one PID occurrence) and 40% of women (after three or more occurrences).

454
Q

Ectopic pregnancy - Which does not predispose

PID

Previous miscarriage

Appendicitis

Endometriosis

IUCD

A

Appendicitis

455
Q

Cervical cancer correct

Improved rates post HSV vaccination

Spread to pelvic wall is Stage II has a poor prognosis

Lymphadenopathy first along the gonadal vein and retroperitoneum

The combined in situ lesions have a 5yr 50% chance of turning into cervical carcinoma

Most patient die from local complications

A

Most patient die from local complications TRUE Most die from local tumour extension rather than distant metastases

Improved rates post HSV vaccination (yes HSV…trick, didn’t mention HPV) Improved post HPV vaccination- most closely associated with HPV 16 and 18

II - beyond the uterus, but not to the pelvic side wall
A - Involvement of the upper 2/3 of vagina
B - involvement of the parametrium
III - involvement of the lower 1/3 of vagina, pelvic side wall, hydronephrosis or pelvic/para-aortic node involvement

Incorrect, usually iliac and obturator nodes first > common iliac > para-aortic

456
Q

Orbital Tumours most correct

Uveal melanoma metastases to liver

Retinoblastomas usually bilateral

? Something about capillary haemangioma of orbits in adults

A

Uveal melanoma metastases to liver

Most common intra-ocular malignancy in adulthood is uveal mets (typically to choroid). Most common intra-ocular primary is uveal / choroidal melanoma. Breast cancer followed by prostate, melanoma and lung are most likely to metastasise to the orbit.

Cavernous malformations / haemangiomas, although not true neoplasms, are the most common benign adult orbital tumour.

Orbital lymphoma is the most common orbital neoplasm in older adults (>60)

Retinoblastoma
- Bilateral 30-40% of cases - always have a germline mutation
- Unilateral 60-70% - are a germline mutation in 15% of cases, 85% sporadic
- So ~55% are related to a germline mutation

457
Q

Fat embolus not correct

Haemorrhage and oedema in lung

Usually occurs 1-3 days post trauma

Petechial rash

Usually after long bone fracture

Contains adipose tissue

A

Contains adipose tissue

Represents microscopic fat globules with or without haematopoietic marrow elements

458
Q

Brown pigment biliary stones

TPN

Haemolysis

Hypertriglyceridemia

A

none, infection

Pigment stones can be black or brown. These account for 10% of stones and have a low cholesterol content <20%.

Black pigment stones relate to chronic haemolysis, cirrhosis or intestinal malabsorption.

Brown stones relate to bacterial infection, parasitic infection (Clonorchis) and biliary stasis.

They can be formed where there is intraductal stasis and chronic colonisation of bile with bacteria i.e. postsurgical strictures, choledochal cysts.

Most (80%) stones are mixed and only 10% considered cholesterol stone (i.e. >50% cholesterol content). Risk factors for cholesterol and mixed stones include female gender, older age, diet, rapid weight loss, obesity, OCP and TPN.

459
Q

Fibrous cortical defect least likely

In femur

Permeative (moth eaten) margins on xray

A

Permeative (moth eaten) margins on xray

A fibrous cortical defect is a fibroxanthoma, identical to a NOF although are < 3 cm.

They are very common, most typically seen between 2 – 15 yrs of age.

There is a slight male predilection.

Typically in the metaphysis or diametaphysis and most common in the distal femur or tibia.

Much less common in the upper limb.

They are lucent cortical defects with a thin rim of sclerosis.

There is no involvement of the medullary cavity and no periosteal reaction.

460
Q

GIST correct

Small and large bowel commonest sites

GIST is a generic term encompassing leiomyoma and leiomyosarcoma

Exophytic mucosal lesion

Associated with NF1 Multiple in MEN1 (or maybe it said NF1?)

A

Associated with NF1 Multiple in MEN1 (or maybe it said NF1?) Associated with NF1, Carney triad and Carney-Stratakis syndrome

461
Q

Testicular tumour associated with gynaecomastia

Leydig

Seminoma

A

Leydig

Leydig cell tumours account for 2% of testicular tumours.

Mostly occur between 20 – 60.

Can produce oesotrogens and/or corticosteroids. 10% are invasive and metastatic.

GCTs account for 95% of testicular tumours and are generally malignant. The sex cord stromal tumours are usually benign.

Most GCTs are mixed (60%), containing a mix of seminoatous and non-seminomatous components.

Seminomas account for 50%, peak incidence 30 – 40. Spermatocytic seminomas are rare (1-2%) and mostly in patients > 65.

They have a good prognosis and are not associated with intra tubular germ cell neoplasia (a precursor to GCTs).

462
Q

Eye painless inf rectus and medial oblique involvement, adjacent stranding

Thyroid eye

IgG4

Pseudotumour

A

Thyroid eye

463
Q

 Regarding penis pathology which is incorrect;

Phimosis increased risk of SCC

???SCC and Bowen Disease (condolymata 6, 11)

Hypospadias and UTI

Epispadias and sterility

Circumcision protects against HPV

A

Epispadias and sterility – Sterility is not infertility

Fertility is lower with epispadias

464
Q

Upper zone calcified and non calcified nodules as well as hilar calcified and non calcified lymphadenopathy

Treated TB

Sarcoidosis

Silicosis

A

Silicosis

465
Q

Renal calculi most likely

Struvite calculus and proteus

People with hypercalemia develop stone

A

Both are true - Likely A

Struvite (MAP) stones are associated with chronic infection by urea splitting organisms and staghorn calculi. Proteus is one of these organisms that can convert urea to ammonia.

These calculi tend to precipitate in alkaline urine.

Most stones are calcium containing and associated with hypercalcaemia or hypercalcuria (60%). Other conditions that can contribute include hyperoxaluria and hyperuricosuria. Up to 20% have no demonstrable metabolic activity.

466
Q

Haemochromatosis least correct

Erosions and subchondral cysts

Beaked (or hook?) osteophytes

Symmetric and bilateral

Chondrocalcinosis

Most commonly involves 4th and 5th MCPJs

A

Most commonly involves 4th and 5th MCPJs

Usually 2nd and 3rd MCPs

467
Q

HADD most correct

Linear

Intra-articular

Cloudy intra-articular calcifications

Focal periarticular calcification

A

Focal periarticular calcification

Peri-articular > intra-articular deposition of HA crystals. More appropriately called calcific periarthritis / enthesitis / tendinitis.

Foci are typically round – ovoid and either ill or well defined. Can be intra-articular. 

468
Q

Parotid LEAST correct

Warthins can occur in lymph nodes

Anaplastic better prognosis

Mucoepidermoid can have perineural spread

Pleomorphic adenoma can be radiation induced

Adenoid cystic frequently recurs

Something about acinic? Most common in parotid

A

Anaplastic better prognosis - worst prognosis

469
Q

Regarding thyroid cancer most correct

Follicular most common

Hurthle cell tumour has C cells

Anaplastic has a good prognosis

Papillary associated with something (?MEN1) or Medullary associated with MEN2

A

Papillary associated with something (?MEN1) or Medullary associated with MEN2

Most cases of medullary are sporadic, but also associated with MEN 2 A and B

470
Q

Phaeochromocytoma most correct

MRI most sensitive ~98%

In and MIBG stuff: Differentiating between benign and malignant

Iodinated contrast contraindicated in metastatic phaeo

A

MRI most sensitive ~98%

471
Q

Wegners most likely to affect

Trachea (maybe upper airway)

Heart

Smooth muscle / skeletal muscle

Small bowel

A

Trachea (maybe upper airway)

Wegner is a multisystem non caseating necrotising granulomatous cANCA positive vasculitis affecting small – medium sized arteries, capillaries and veins.

The triad is classically:
- Lung involvement
- Upper respiratory tract / sinus involvement
- Renal involvement

Can range from focal or segmental to crescenteric / proliferative glomerulonephritis

GI and cardiac involvement is uncommon.

472
Q

Ductal pancreatic adenocarcinoma associated with

BRCA 2

Li Fraumeni

MEN 1

Carney triad

A

BRCA 2

Li Fraumeni
- AD inherited mutation in p53
- Increased risk of breast cancer, sarcoma, leukemia, multiple CNS tumours, adrenocortical carcinoma

BRCA 2
- Breast cancer (30-90%) by aged 70
- Ovarian
- Male breast
- Prostate
- Pancreas
- Stomach
- Melanoma
- GB and bile duct
- Pharyngeal
- Note BRCA1 is less associated with male breast cancer but more associated with ovarian ca.

MEN 1 ‘3 P’
- Parathyroid hyperplasia > adenoma > carcinoma
- Pituitary adenoma
- Pancreatic neuroendocrine tumours

Carney triad ‘Carney’s eat garbage’
- Chondroma (pulmonary) i.e. hamartoma
- Extra-adrenal phaeochromocytoma
- GIST

peutz jegher even higher

473
Q

Trisomy 21 least likely to be associated moderately increased risk of

Secondary biliary cirrhosis

Leukaemia - AML

Alzheimers

ASD

Atlantoaxial subluxation

A

Secondary biliary cirrhosis

474
Q

Pagets nipple least likely:

Looks like ulcerating SCC

Involves nipple before areola

Commonly associated with invasive ductal carcinoma

Approximately 100% ipsilateral DCIS

Often ipsilateral IDC

A

Looks like ulcerating SCC

Eczema rather than ulcerating

475
Q

Regarding breast cancer treatment least likely:

Inject subdermal/inferior axilla with dye +/- isotope in the low axilla

Traditional staging included axillary node dissection

Axillary clearance associated with moderate morbidity

Negative sentinel lymph node biopsy correlates to low risk of LN involvement

A

Traditional staging included axillary node dissection

476
Q

Least likely to be a spiculated breast mass (2 questions)

PASH

ILC

Tubular carcinoma

Adenosis

Fat necrosis

A

PASH

PASH is not commonly a spiculated mass, normally it is a circumscribed or partly circumscribed mass.
- Can mimic a fibroadenoma on ultrasound.

ILC is often multicentric and bilateral.
- Sensitivity of mammogram for ILC is up to 80%.
- It most commonly appears as a spiculated mass.
- Less commonly asymmetric density, architectural distortion or region of microcalcifications.
- Up to 16% are occult or benign appearing.

Tubular carcinoma is a subtype occurring in younger women with a good prognosis.
- It is usually a small <1cm spiculated mass.
- They are associated with radial scars.

Adenosis can be difficult to distinguish from an infiltrating carcinoma.
- It can appear as a mass, region of architectural distortion or demonstrate microcalcifications (up to 55%).

477
Q

Ewings sarcoma (2 separate qns) ?true

Age range 15-20

Most commonly in the metaphysis

Most commonly diaphyseal, or flat bones of the pelvis

Can mimic Neuroblastoma

Preference for liver mets is a known phenomenon

A

Can mimic Neuroblastoma – histologically yes

478
Q

t/f beta catenin adenomas have increased risk of malignant transformation

A

true

Beta catenin have the highest rate of malignant transformation of the adenoma subtypes.

Inflammatory type is most common and has the highest bleed rate.

HNF1 alpha Is second most common type and most often multiple

Beta-catenin mutated are the least common.

Seen in men on anabolic steroids, glycogen storage disease and with FAP

479
Q

Which of the following is not associated with Tuberous Sclerosis Complex

SEGA

Hamartomas

Leptomeningeal angiomatosis

A

Leptomeningeal angiomatosis

Associated with Sturge-Webber, NF-1

480
Q

Which of the following is LEAST associated with TS

Cortical hamartomas

SEGA

Rhabdomyoma

LAM

Subependymoma

A

Subependymoma

TS is associated with subependymal giant cell astrocytomas (SEGA).
- These are WHO grade 1 lesions most commonly seen in age group 8 – 18 with TS.
- They are most commonly located near the Foramen of Monro and can be differentiated from subependymomas by larger size (>1 cm), interval growth, marked enhancement.

Subependymomas are more common in middle – older aged patients and are more commonly located in the 4th ventricle and frontal horns of lateral ventricles.

481
Q

Fibrolamellar HCC least likely

Are well differentiated

Worse prognosis than traditional HCC

Thick fibrous capsule (?answer) have a pseudo capsule..

Age 20-40

A

Worse prognosis than traditional HCC - Better prognosis than HCC

FL HCC – most common aged 20-40,
- Often well-differentiated, and
- Usually don’t produce AFP elevation.
- May contain a central scar which is usually hypointense on all phases.

482
Q

Primary haemochromatosis does not cause iron deposition in

Spleen

Heart

Liver

Pancreas

A

Spleen

483
Q


Rheumatoid arthritis most likely

Can have pulmonary nodules at presentation

Spares the small joints of the feet

Often presents with honeycombing / early presentation with honeycombing

Renal failure is most commonly caused by rheumatoid vasculitis

A

Can have pulmonary nodules at presentation

More common with longstanding disease

484
Q

Which can cause a cardiomyopathy

Takayasu

Kawasaki

Churg straus

Wegners

Goodpastures

A

Takayasu Hypertrophic cardiomyopathy

eosinophilic Churg Strauss cardiomyopathy
Can cause a cardiomyopathy in up to 60%, most common cause of death

485
Q

Guy with massive pulmonary haemorrhage and fibrocavitating upper lobe disease. Angiogram looks at bronchial arteries, which is most likely finding

Aneurysm

Dissection

Beads and line appearance

Neovascularity

A

Neovascularity

Haemoptysis usually arises from the bronchial arteries due to changes in the terminal vascular bed

aneurysm second most likely (TB)

486
Q

Mycobacterial disease least associated with

Gohn focus

Asbestosis

Silicosis

Emphysema

Immunosuppression

A

Asbestosis

487
Q

Mesothelioma least likely

Difficult to distinguish from secondary adenocarcinoma

Pleural effusion early presentation

Parietal and visceral pleura involved

Peritoneal mesothelioma is rare

Commonly associated with smoking

A

Commonly associated with smoking- false

“Mesothelioma of the thorax is a malignant neoplasm that involves the parietal pleura to a greater extent than the visceral pleura (,1).

There is a significantly increased risk of developing this disease in those individuals with prior exposure to asbestos.

The lifetime risk of developing mesothelioma in heavily exposed individuals is as high as 10%.

There is a long latent period of approximately 35–40 years for the development of asbestos-related mesothelioma (,1).

However, there has been no evidence to suggest smoking plays any role in the development of mesothelioma. This is in contrast to the significantly increased risk for development of adenocarcinoma in those patients who both smoke and have been exposed to asbestos”

488
Q

Meigs not associated with

Fibroma

Thecoma

Dysgerminoma

Brenner

Granulosa

A

Dysgerminoma

MEIGS: Defined by the presence of ascites, pleural effusion (usually right sided) in associated with a benign usually solid ovarian tumour.

In the vast majority of cases (up to 90%), the primary tumour is an ovarian fibroma.

Other primary tumours include:
- Fibrothecoma
- Thecoma
- Granulosa cell tumours of the ovary
- Brenner tumour

A dysgerminoma is the most common malignant germ cell tumour (only 1%). Usually occur in the 2nd and 3rd decades. Thought to be the ovarian counterpart of the seminoma in the testis.

489
Q

t/f afp up in 90% hcc

A

false, 75%

490
Q

 Gestation trophoblastic disease least likely

Partial mole is Triploid - 69 XXX or 69 XXY

10% invasive

2-3% choriocarcinoma in partial mole

Bimodal with young and older mothers

A

2-3% choriocarcinoma in partial mole

Never proven

491
Q

Polycythemia vera, which is false?

Gallstones

Gout

Transformation to AML

Venous occlusion

A

Gallstones

492
Q

Gout most correct:

Juxta-articular erosions

1% of the population have asymptomatic hyperuricaemia

A

Juxta-articular erosions

closer to 10%

493
Q

Adenomyosis :

Symmetric enlargement of the uterus

Venous involvement

1% of middle age women autopsies

Clonal something

Lack of response to cyclic hormones early

A

Symmetric enlargement of the uterus - as opposed to nodular thickening

Enlargement can be diffuse or more focal

494
Q

Gallbladder adenomyomatosis in radiodiagnosis, which is false

No association with malignancy of GB

Something about focal and diffuse (? diffuse adenomyomatous can mimic )

A

No association with malignancy of GB - Not premalignant, but found in associated with chronically inflammed gallbladder

Adenomyomatosis is common, 9% of autopsy specimens.

More common in females at 3:1.

Pathologically involves formation of Rokitansky – Aschoff sinuses, intramural diverticula lined by mucosal epthelium, which penetrate into the muscular wall of the GB.

Cholesterol crystals precipitate in the bile trapped in these sinuses.

495
Q

Gallbladder cancer most correct

Mostly infiltrative not exophytic

Females more than males

Most diagnosed at early stage

A

Females more than males
3-5:1

Major risk factors are female gender, age and chronic biliary inflammation i.e. gallstones present in 95% of cases

496
Q

urinary bladder malig most important prognostic factor

A

detrusor muscle involvment

Although lamina propria involvement worsens prognosis, involvement of the muscularis propria / detrusor is the major determinant of outcome as can be treated with BCG, where if invaded through needs cystectomy

Staging of bladder cancer
Tis – in-situ
T1 – through lamina propria
T2 – into muscularis propria
T3 – invasion into perivesical tissues
T4 – direct invasion into adjacent structures including prostate, uterus, vaginal vault

497
Q

Prostate cancer most correct

Occurs in transitional zone

T3 is extraprostatic extension

PSA is very specific for prostate cancer

Some weird histo grading system starting with ?Fahman (not gleason)

A

T3 is extraprostatic extension

T3: localised extra-prostatic extension

498
Q

Cervical cancer most correct

Stage II involves pelvic sidewall

SCC worse than neuroendocrine

A

both incorrect

Stage II involves pelvic sidewall
- False
- III: low 1/3 of vagina, extends to pelvic sidewall or causes hydronephrosis or has para-aortic/pelvic nodal disease
- II: tumour beyond the uterus, but not into the lower 1/3 of the vagina or pelvic side wall

SCC worse than neuroendocrine
- False, Neuroendocrine has worse prognosis

499
Q

Most likely cortically based tumour

DNET

JPA

A

dnet

DNET is a cortically based tumour. Mnemonic is DOG Pee
- DNET
- Oligodendoglioma
- Ganglioglioma
- Pleomorphic xanthoastrocytoma

500
Q

 Cardiac myxomas least likely

Systemic emboli

Pulmonary emboli

Valvular damage / dysfunction

Fever

A

Pulmonary emboli – less likely as 75% are in the left atrium

501
Q

nelson syndrome

A

bilateral adrenelectomy causing pit macroadenoma

502
Q

Endocarditis least likely

10% have positive BCs

Abscess in sewing ring

Subacute in a damaged valve

Staph in elderly

Right sided valves >50% in IVDU 

A

10% have positive BCs

In 10% no organism is identified

503
Q

Young lady DI and hypopituitarism

Empty sella

Rathke

Lymphocytic hypophysitis

Craniopharyngioma

A

Lymphocytic hypophysitis

More common in women 8:1M

Most common ~35yo

Commonly presents in the peripartum period with headache and endocrine deficiencies

Can cause DI

504
Q

are mature teratomas benign in an adult

A

yeah pretty much

A mature teratoma is a dermoid, a benign ovarian germ cell tumour.

Congenital cystic tumour composed of well differentiated derivations of at least 2 germ cell layers.

Bilateral in 20% of patients.

They represent the most common benign ovarian tumour in women < 45 years.

Risk of malignant transformation is <2% and most commonly an SCC.

Usually occurs in the 6th – 7th decades of life in larger tumours <10 cm.

505
Q

Which is least likely

Idiopathic UIP has a better prognosis than NSIP

Idopathic UIP has a worse prognosis than NSIP

A

Idiopathic UIP has a better prognosis than NSIP

506
Q

t/f Neonatal cirrhosis associated with Alpha 1 anti-tripsyin

A

true

Leading causes of neonatal cirrhosis include:
- Biliary atresia
- Choledochal cysts
- Viral hepatitis
- Alpha 1 antitrypsin deficiency
- Alagille syndrome - proximal biliary duct obliteration, Liver disease
- Progressive familial intrahepatic cholestasis

“Alpha-1-antitrypsin deficiency is a commonly inherited genetic disorder, affecting up to 1 in 1,600 to 1 in 2,000 live births[1,2], most common in those of Northern European heritage.

Individuals who are homozygous for the mutant Z allele (PiZZ) or are PiSZ are at risk for the development of liver disease.

Although emphysema is rarely detectable before the third decade of life, liver disease can present at any age and can be evident as early as 1-2 months after birth.

Four to ten percent of children with alpha-1-antitrypsin deficiency develop clinically significant liver disease during their first twenty years of life, making alpha-1- antitrypsin deficiency the most common genetic cause of pediatric liver disease and the most frequent inherited indication for liver transplantation in the pediatric population”

507
Q

Wilsons least correct: (so many questions about wilsons & haemochromatosis)

Autosomal recessive

Deposing in lentiform nucleus causing movement disorder

Elevated serum ceruloplasmin

No increase risk of cancer

A

Elevated serum ceruloplasmin

reduced

atp7b gene

508
Q

is haemochromatosis assoc with parkinsons

A

Parkinsonism is associated

Primary haemochromatosis – AR disorder with mutation in HFE gene, regulating iron absorption from the GIT. This leads to reduced hepcidin synthesis.

Iron accumulates as haemosidein in various tissues including liver, pancreas, myocardium, endocrine glands, joints and skin.

CNS involvement is relatively less common. It can present with hypopituitarism or movement disorders such as Parkinsonism due to basal ganglia.

509
Q

 Wilms least associated with

Denys drasher

WAGR

Hutchinsons

Pearlman syndrome

Beckwith weidman

A

Hutchinsons
Neuroblastoma syndrome

Wilms is a malignant tumour of primitive metanephric blastema.

It is associated with a predisposing syndrome in 10%:
- Bewkwith-Wiedemann
- WAGR
- Denys-Drash
- Sotos
- Pearlman syndrome

Other isolated abnormalities – cryptorchidism, hemihypertrophy, hypospadias, aniridia

510
Q

Giant cell tumour

Joint was knee - GCT occurs at the knee

Tendon hands wrist

Red brown appearance due to haemosiderin deposition

Can invade bone and joint

A

Tendon hands wrist

85% around the fingers, with a volar/flexor surface

Most commonly superficial and near the IP joints of the index and long fingers

Hand > wrist > ankle/foot > knee

511
Q

 Regarding diabetes which is true

Type 2 has higher incidence of renal failure than type 1

Associated with mononeuropathy

Leading cause of death is by infection

Macrovascular complications don’t include coronary artery disease

Most diabetics get retinopathy

A

Most diabetics get retinopathy

True, 78% of type 2

they also can have mononeuropathy

512
Q

Regarding late pregnancy t/f

Pre eclapsia is associated with seizures

Gestational hypertension is associated with proteinuria

A

Pre eclapsia is associated with seizures
False, seizures occur in eclampsia

Gestational hypertension is associated with proteinuria
False, proteinuria = pre-eclampsia

Gestational hypertension is characterised by the new onset of hypertension after 20 weeks gestation without any maternal or fetal features of preeclampsia, followed by return of blood pressure to normal within 3 months post-partum. At first presentation this diagnosis will include some women (up to 25%) who are in the process of developing preeclampsia but have not yet developed proteinuria or other manifestations. Some women initially diagnosed in this category will manifest persistent blood pressure elevation beyond 12 weeks postpartum and eventually be classified as having chronic hypertension. Gestational hypertension near term is associated with little increase in the risk of adverse pregnancy outcomes “

Pre-eclampsia usually occurs after the 34th week of pregnancy. It is associated with hypertension and microalbuminuria in 20% post delivery as well as an increase in risk for heart and CNS vascular disease.

513
Q

Low lying tonsils, Obex of medulla oblongata elongated.

Chiari 0

Chiari 1

Chiari 1.5

Chiari 2

Chiari 3

A

Chiari 1.5 - complex chiari malformation, low opex

514
Q

Heart most correct

Moderator bands can mimic masses

Pericardial cysts most likely on left

A

Moderator bands can mimic masses

Morphological part of the right ventricle.

Extends from the IV septum to the margin of the RV, contacting/joining the base of the anterior papillary muscle

515
Q

Female, for bone age wrist study. Short stature with short 4th metacarpal

Turner’s

MPS

Achondroplasia

A

Turner syndrome is 45 XO

Skeletal deformities include a short 4th metacarpal,
- Madelung’s deformity,
- narrowing of the scapholunate angle,
- short stature,
- webbed neck,
- abnormal medial femoral condyle, and
- cubitus valgus.

516
Q

Hemifacial spasm

AICA loop

Diffusion restriction at CP angle

Diffusion restriction in 4th ventricle

Lesions of corpus callosum

A

AICA loop

Hemifacial spasm can occur due to irritation of the facial nerve usually at the root exit zone.

An aberrant vascular structure is often a cause.

The vessels most commonly implicated are AICA, PICA and the vertebral artery.

Other causes include cholesteatoma, schwannoma, meningioma, intracranial lipoma and AV malformation.

517
Q

STIR achieved by

Suppressing fat based on relaxation time

Suppressing fluid based on relaxation time

Suppressing fluid based on chemical shift

A

Suppressing fat based on relaxation time

a- STIR is ‘short Tau inversion recovery’ and is a fat suppression technique. It is a similar technique to FLAIR which is used to suppress water. Inversion recovery imaging allows homogenous and global fat suppression and can be used with low field strength magnets.

518
Q

ost correct in anaphylaxis

Decreased response to adrenaline in patients on Beta blockers

IM 1:10000 adrenaline is contraindicated

A

Decreased response to adrenaline in patients on Beta blockers

A reduction in response to adrenaline is expected in patients on beta-blockers

519
Q

 Least correct about interstitial ectopics

Occurs in mural portion

Interstitial line

5mm myometrium

Interstitium is contiguous with endometrial canal

Deciduous reaction (double decidual sign) of endometrium

A

Deciduous reaction (double decidual sign) of endometrium

“In normal pregnancies, transvaginal US can demonstrate an intradecidual sign approximately 4.5 weeks after the last menstrual period (,12). The intradecidual sign is a small collection of fluid that is eccentrically located within the endometrium and is surrounded by a hyperechoic ring. At approximately 5 weeks, the double decidual sac sign can be visualized. The double decidual sac sign consists of two concentric hyperechoic rings that surround an anechoic gestational sac in a normal intrauterine pregnancy. The absence of the double decidual sac sign helps distinguish a pseudo–gestational sac from a true viable gestational sac”.

Note interstitials have a higher propensity to rupture due to later presentation and ability to grow to larger size. Major risk factor is previous instrumentation.

520
Q

Middle aged female, 3 days of increasing knee pain. Red and pain. Effusion. Swelling. most likely

Septic arthritis

RA

A

septic

521
Q

Worded exactly “which does not cause A single sclerotic bone lesionS”

Eosinophilic granuloma

Anklyosing Spondylitis

Haemangioma

Insufficiency fracture

Osteomyelitis

A

Eosinophilic granuloma

522
Q

Vascular closure device most correct

Bio puts a collagen disc in the vessel wall

<5mm diameter artery contraindicated for suture devices

Suture closures cause an inflammatory reaction

Compression contraindicated in staples

Can’t re-puncture after collagen biodevice in the same site

A

<5mm diameter artery contraindicated for suture devices

523
Q

Previous trauma, diaphragm injury. Multiple solid pleurally based masses in L hemithorax

Splenosis

Loculated pleural effusions

A

Splenosis

524
Q

Not associated with COP

Reverse halo/Atoll sign

Ground glass

Masses

Dilated bronchi in the abnormal lung

Nodular interlobular septal thickening

A

Nodular interlobular septal thickening

Features include:
- Most commonly – patchy, migratory subpleural and / or peribronchovascular consolidation
- Less commonly – single pulmonary nodule or mass, multiple pulmonary nodules, parenchymal bands, basilar reticular opacities. Bronchial dilatation within consolidation or GGO is listed as a HRCT manifestation on StatDx.
- Tends to be a middle lobe, lingular and lower lobe predominance
- Most frequent finding is GGO (90%)
- Reverse halo ‘atoll’ sign seen in 19% of cases – ring of parenchymal consolidation surrounding GGO
- Classic for COP. Also seen in invasive fungal infection including aspergillosis and mucormycosis, pulmonary infarction, Wegeners, infection, sarcoid

525
Q

 Early pregnancy. Unsure of dates. CRL 6mm. No heart rate. No adnexal masses. Ovary has a ‘ring of fire’. What is going on

Failed early pregnancy.

Indeterminate - needs repeat

Normal go to normal antenatal care

Heterotopic pregnancy

A

Indeterminate - needs repeat

if CRL is < 7 mm and no heart beat this is suspicious but not diagnostic of pregnancy failure.

Follow up in 7 – 14 days would be appropriate.

If it were 7 mm, it would be diagnostic.

Findings diagnostic of pregnancy failure
- CRL >/= 7 mm and no HR
- MSD OF >/= 25 mm and no embryo
- absence of embryo with heartbeat ≥2 weeks after a scan that showed a gestational sac without a yolk sac
- absence of embryo with heartbeat ≥11 days after a scan that showed a gestational sac with a yolk sac
- pregnancy with an embryo with no heart activity on initial scan and repeat scan ≥7 days later
- sac with no embryo and an MSD <12 mm on initial scan that fails to double in size on a scan ≥14 days later
- sac with no embryo and an MSD ≥12 mm on initial scan with no embryo heart activity on a scan ≥7 days later 2

Findings suspicious but not diagnostic of pregnancy failure
- CRL < 7 mm and no HR
- MSD 16 – 24 mm and no embryo
- Absence of embryo > 6 weeks post LMP
- Large yolk sac > 7 mm
- Small GS in relation to size of embryo i.e. < 5mm difference between MSD and CRL
- Amnion seen adjacent to YS but no embryo i.e. empty amnion sign
- Absence of embryo with heartbeat 7-13 days after a scan that showed a gestational sac without a yolk sac
- Absence of embryo with heartbeat 7-10 days after a scan that showed a gestational sac with a yolk sac
- Large amniotic cavity

526
Q

When is it most indicated to perform MCA dopplers

DCDA twins

Concern of Parvo virus

EFW <5% and AC <5%

A

EFW <5% and AC <5% (parvo also correct)

Fetal MCA doppler used for
- Assessment of fetal cardiovascular distress, anaemia and hypoxia
- IUGR
- Assessment of possible monochorionic twin related pregnancies including TTTS and TAPS

Accurate measurement
- Fetal head in transverse
- Cross section including the thalami and sphenoid bone wings magnified
- MCA found with colour or power doppler
- Obtain measurement as close to its origin in the ICA (systolic velocity decreased away from this point)
- Angle of insonation of < 15 degrees

Parameters
- PI (pulsatility index)
- PSV (peak systolic velocity)
- S/D ratio (systolic/diastolic) – a normal MCA S/D ratio should ALWAYS be higher than the UA S/D ratio
- CPR (cerebroplacental) ratio – ratio of MCA PI and UA PI

Interpretation
Normal
- High resistance flow i.e. minimal antegrade flow in fetal diastole
- CPR > 1:1
- The PI is calculated by (PSV – EDV) / TAV (time averaged velocity) It normally has a high value and slowly decreases through gestation from around 28 weeks onwards. A low PI reflects redistribution of cardiac output to the brain.

Abnormal
- Fetal anaemia
- Elevation of PSV in MCA
- Elevated is > 1.5 MoM for gestational age (multiple of the median)
- Fetal head sparing theory, MCA becomes a low resistance vessel

IUGR
- Asymmetric is the more common form and usually presents in T3. AC is reduced out of proportion to other fetal biometric parameters. AC is < 5 - 10th centile. There is often associated oligohydramnios.
- A PI is recommended in the MCA if the EFW or AC are < 10 %,

The PI is normally high and will slowly decrease through gestation from 28 weeks onwards. If it is low, this represents redistribution of cardiac output to the brain due to the fetal head sparing theory (low PI think low resistance therefore redistribution)

Brain sparing physiology will be adapted, with an increase in MCA diastolic flow and a reversal of the normal ratio between the MCA S/D and UA S/D

CPR is a ratio of the PI in the MCA vs the UA. An abnormal ratio is low and again reflects brain sparing. If the ratio is low it can indicate either an increase in placental resistance or a reduction in cerebral resistance. An abnormal CPR can thus occur even if the UA and MCA parameters are within normal limits, i.e. the MCA would be lower normal range and the UA PI at the upper normal range. Abnormal is < 5th centile or based on MoMs. Generally < 1:1 is abnormal.

527
Q

Indicated to repeat US post morph scan

Velamentous cord insertion

Cervical length 27mm

Renal pelvis <4mm

A

Cervical length 27mm

Best measured in TV with an empty bladder

Normal >30mm

The presence of a full bladder can increase the length, esp on a TA study

528
Q

 Regarding vasa previa (or vasera) most correct

Important to establish is fetal or maternal

Check duplexes

Associated with marginal cord insertion

A

In all cases where a multilobed or succenturiate placenta or low lying placenta or velamentous cord insertion is identified, a TV scan with assessment of the lower uterus / cervix should be performed to assess for vasa previa.

There are two main types of previa:

Type 1 – 90% of cases. Vasa previa with velamentous cord insertion. Low-lying vessels from low cord insertion.

Type 2 – 10%. Low lying vessels connect bilobed or succenturiate lobes.

529
Q

Pansystolic murmur, exertional syncope. Upturned cardiac apex on CXR, with dilated ascending aorta.

Pressure gradient across AV valve >50mmHg

Some other valves mentioned as the pathological cause

A

Pressure gradient across aortic valve is mostly used as a marker of aortic stenosis, where there would be an elevated pressure across the valve (i.e. higher in the ventricle).

Core (p 681):
If the aorta is enlarged and the cardiac silhouette is, this suggests AR.

If the aorta is enlarged and the cardiac silhouette is not, this suggests AS.

Pansystolic murmur seen in MR, TR and VSD. AS typically has an ejection systolic murmur but could result in exertional syncope and a dilated ascending aorta.

Upturned cardiac apex implies right ventricular enlargement – secondary to PAH, PV, ASD/ VSD, TR, DCM or TOF.

Not sure what the answer or question is here.

530
Q

Old lady with lower limb oedema and ascites. Most likely finding on CT chest

A

Reflux of contrast into the IVC and dilated hepatic veins 

531
Q

35 year old female, mother breast Ca at 60. Has a lump in breast. Mammo 2cm well circumscribed mass, and benign sounding US description. Most likely

Cancer

Phyllodes

Fibroadenoma

A

Fibroadenoma

532
Q

 What is not associated with thoracic outlet obstruction

AC dislocation

Callous on clavicle fracture

Cervical rib

Hyperostosis 1st rib

Elongated C7 transverse process

A

AC dislocation

533
Q

Hypoechoic lesion seen in kidney on US, thought indeterminate. MRI shows T1 low,
T2 high, no enhancement

Simple Renal Cyst

RCC

Oncocytoma

AML 

A

Simple Renal Cyst

534
Q

40 year old man, 3cm renal mass. US hypoechoic. On MRI T1 hypo, T2 hyper, mild internal enhancement

Clear cell RCC

Cyst

Proteinaceous cyst

Haemorrhagic cyst 

A

Clear cell RCC

535
Q

Which way does disease not spread from “pterygopalatine fissure” (exact wording)

Anteriorly to maxillary sinuses

Post to brain

Superiorly to orbit

Laterally to infratemporal fossa

Medially to nasal cavity

A

Anteriorly to maxillary sinuses

536
Q

5 year old, T1 low, T2 high 2cm mass at dorsal nose with a tract to the foramen caecum of frontal bone

Nasolacrimal dacrocystocele

Nasal dermal sinus

Encephalocele

A

Nasal dermal sinus
- Represents defective embryogenesis of the anterior neuropore
- Any mixture of dermoid, epidermoid or sinus tract
- A fluid tract signal in the septum, from nasal dorsum to skull base

The foramen caecum represents a primitive tract between the anterior cranial fossa and the nasal space. It is located along the anterior cranial fossa, anterior to the cribriform plate of the ethmoid bone and posterior to the frontal bone, within the frontoethmoidal suture. It lies at a variable distance anterior to the crista galli.

A variety of midline nasal pathologies may occur along this transient embryologic communication:
- nasal encephalocele T2 hyperintense - extension of brain
- epidermoid or dermoid cyst - associated with skin sinus tract or dimple, extends along foramen cecum, and
- nasal glioma isointense to normal brain, no tract, extra bit of brain without continuation of cortex 

537
Q

Which is least likely to be a sacral mass with soft tissue component

Chondroblastoma

GCT

Ewing

Lymphoma

?Met

A

Chondroblastoma - soft tissue expansion rare.

Usually epiphyseal in young patients

538
Q

Acute weakness in arm. Diffuse STIR high signal in supraspinatus, infraspinatus and teres minor. Normal T1 signal in muscles. Cause?

Brachial neuritis

Quadrilateral space syndrome

Acute Suprascapular nerve impingement at spinoglenoid notch

Acute Suprascapular nerve impingement at suprascapular notch

Chronic impingement 

A

ANSWER: Brachial neuritis
- Suprascapular nerve is involved in almost all cases
- Axiallary and subscapular nerves can also be involved

Quadrilateral space syndrome
- Humerus laterally, long head of triceps medial, teres major and minor superior and inferior
- Axillary nerve and posterior humeral circumflex artery
- Results in teres minor +/- deltoid involvement

Acute Suprascapular nerve impingement at spinoglenoid notch
- Spinoglenoid notch - below the scapular spine, results in infraspinatus atrophy

Acute Suprascapular nerve impingement at suprascapular notch
- Suprascapular notch, medial to the coracoid, results in supra and infraspinatus atrophy

539
Q

45M neck mass and difficulty swallowing. CT well defined thin walled mass with airfluid level crossing thyrohyoid membrane. Most likely?

Laryngocele

Abscess

Thyroglossal cyst

Lymphatic malformation

Epidermoid Cyst

A

Laryngocele

540
Q

5 year old with a 2cm lump on chin (5HU) also has several small nodules in floor of mouth (-30HU)

Dermoid

Ranulla

Lymphatic malformation

A

Lymphatic malformation

This is favoured as it is a trans-spatial process. Lymphangiomas are cystic lesions, 90% are in the head and neck.

541
Q

Young bloke, painful volar forearm mass, rounded, T1 hypo, T2 hyper, enhancing.

Peripheral nerve sheath tumour

Ganglion

Cyst

Nodular fasciitis

A

This is most likely nodular fasciitis – a non-neoplastic soft tissue lesion most commonly located on the volar aspect of the forearm. Usually patients 20 – 40 years of age.

Can be mistaken for an aggressive lesion on imaging and histology.

542
Q

30 year old female with a big (?9cm) pancreatic cyst (?or did it just say hypoechoic lesion). Most likely

Solid pseudopapillary tumour

Mucinous

IPMN

SPEN

A

SPEN

SPEN most common in non-Caucasian females around the 2nd – 3rd decades of life.

Often large heterogenous solid cystic tumours with a median size at diagnosis of 8 cm.

Most are benign but up to 15% are malignant.

543
Q

HIV cortical echogenic foci in kidneys

CMV nephritis

HIV nephritis

PJP

A

Calcific foci in the cortex are typical of PCP renal infection.

They were initially thought to be pathognomonic but have also been seen in MAC and CMV infection.

544
Q

Gas tract between the ileum and sigmoid colon RLQ pain and fever

Diverticulitis

Crohns

Appendicitis

A

Crohns

Propensity to cause fistulae

545
Q

Intrahepatic ductal dilatations only. Todani classification

1

2

3

4

5

A

5

546
Q

Perianal fistula - grade 5

A

supralevator

Perianal fistula grading:
- 1 – Intersphincteric
- 2- Intersphincteric with abscess
- 3- Transphincteric
- 4 – Transphincteric with abscess
- 5 – Supralevator or translevator

547
Q

Child lytic skull lesion T1 low/isointense and T2 high lesion on MRI

Dermoid

Cyst

EG

A

EG

MRI: T2 high, T1 low to iso, and often diffusely enhancing

Inner table can be eroded more than the outer - hole within a hole

Center of the lesion can contain a sequestrum

548
Q

Single lesion in calvarium of child, centred on Diploic space, T1 iso, T2 hyper

Leptomeningeal cyst

LCH

Met

A

LCH

549
Q

Which has physiological FDG uptake in a 5yr old child

Thymus

Bone marrow

Muscle

A

thymus

Both A and B are correct, maybe more in thymus

“A number of physiologic variants are commonly encountered, including normal physiologic uptake in the head and neck, heart, breast, thymus, liver, spleen, gastrointestinal tract, genital system, urinary collecting system, bone marrow, muscles, and brown adipose tissue

Bone marrow activity that is more intense than liver activity is considered abnormal.

Normal accumulation is generally homogeneous, with more extensive distribution in children than in adults.

The normal distribution of 18F FDG uptake in children is unique and may differ from that in adults, such as the physiologic activity of the lymphatic tissue in the Waldeyer ring, as well as uptake in the ileocecal region, thymus, hematopoietic bone marrow, and skeletal growth center”.

550
Q

Child with facial enlargement, CT showing multilocular mandibular and maxillary lytic/ lucent lesions causing bony expansion

Cherubism

Venous lymphatic malformation

Burkitt lymphoma

A

Cherubism
Autosomal dominant, historically considered a variant of fibrous dysplasia.

Radiographic features are of lucent expanded regions within the maxilla and mandible with soap bubble appearance.

551
Q

Regarding MS not correct

Optic neuritis progresses to MS in 50%

Auto antibodies against myelin sheath

Bimodal age distribution

Something about relapsing remitting

A

Auto antibodies against myelin sheath
- No testable antibody, thought to relate to cellular immune response directed against myelin
- Mostly mediated by CD4+ Th cells

Bimodal age distribution
- Peak onset is childhood and age 50, average age 35. Not really bimodal

552
Q

34yo female with renal insufficiency and headaches. Multiple intra- and extra-cranial aneurysms.

Polycystic kidney disease

FMD

PAN

Takayasu

A

FMD
- Usually medial dysplasia
- Most commonly affects the mid-segment of vessels, spares the ostium
- Renal > extracranial ICA and vertebral > iliac > others
- Can be associated with aneurysms
\

Polycystic kidney disease
- False, AD PCKD is associated with renal insufficiency, but usually presents later
- 6% association with berry aneurysms

553
Q

20yr old pt with headaches, HTN, renal artery ostial stenosis

FMD

PAN

NF1

A

NF1

Renal artery stenosis may be caused by several pathological processes:
- Atherosclerosis (~75% of cases) involves the proximal renal artery
- Fibromuscular dysplasia (~20%) involves the distal renal artery, younger population
- Vasculitides (especially polyarteritis nodosa-causing multiple microaneurysms, Takayasu arteritis, radiation)
- Neurofibromatosis type 1- most commonly involves the ostium
- Abdominal aortic coarctation
- Aortic dissection
- Segmental arterial mediolysis

554
Q

Qns regarding fetal echo

With a R sided arch, trachea is on the left (of the DA presumably) on the 3 vessel view

Ductal arch and bifurcation of pulmonary trunk seen at the same level

Ductal arch is posterior to aortic arch on a sagittal view

Something about an aberrant R subclavian

A

With a R sided arch, trachea is on the left (of the DA presumably) on the 3 vessel view (as opposed to being to the right of the DA on a standard view with a left arch. this also presumes drainage to a right arterial duct).

555
Q

Baby with T21, has distal bowel obstruction, likely

Hirschprung

Ileal atresia

Pyloric stenosis

Annular pancreas

A

Hirschprung

Occurs in 10% of patients with T21

556
Q

Paraneoplastic syndromes which is not true

SIADH

Cushings

Cardiomyopathy

Limbic encephalitis

A

Cardiomyopathy

557
Q

Myasthenia Gravis most correct

Thymoma in 10%

Occurs in the elderly mostly

Fatal in 50%

Antibodies block the release of acetylcholine

Extra ocular involvement

A

Thymoma in 10%

Occur in ~15% of patients with MG

30-50% of patients with a thymoma have MG

558
Q

Sequestration intralobar, commonest lobe

LLL

RLL

RML

RUL

LUL

A

LLL

559
Q

 Extralobar sequestration. Not True:

Presents <1yr age

Drains to pulmonary veins

Males more than females

No systemic arterial supply

A

false: Drains to pulmonary veins
Usually to systemic veins, can be pulmonary

560
Q

Baby with resp distress, CXR initially shows opacity in the L upper zone, next CXR shows a subtle lucency in the left upper zone

CPAM

Sequestration

Congenital lobar emphysema

A

Congenital lobar emphysema

(CPAM can also be fluid filled in early stages. Subtle lucency sounds like CPAM )

The affected lobe tends to appear opaque and homogeneous because of fetal lung fluid or it may show a diffuse reticular pattern that represents distended lymphatic channels filled with fetal lung fluid. appears as an area of hyperlucency in the lung with oligaemia (i.e. paucity of vessels) mass effect with mediastinal shift and hemidiaphragmatic depression

lateral decubitus film with the patient lying on the affected side will show little or no change in lung volume

lateral film may show posterior displacement of the heart

561
Q

 Regarding oesophagus

Zenker diverticulum occurs in the posterior aspect of the upper third of the thoracic oesophagus

Barrets is intestinal metaplasia

Something about scleroderma

A

Barrets is intestinal metaplasia
- Intestinal metaplasia of the oesophagus
- Squamous epithelium becomes columnar

562
Q

Zollinger ellison syndrome is

A

Polyps in stomach

ZE is a syndrome secondary to a gastrinoma with subsequent gastrin hypersecretion.

Gastrinomas are usually multiple and typically located in the duodenum.

Associated with MEN1.

More than half have metastatised by presentation.

Findings include thickened gastric folds/gastritis, erosions and ulcers (particularly in atypical locations).

563
Q

Alcoholic young man (20 something) has pain swallowing, barium swallow shows mucosal irregularities in lower oesophagus. Likely

Cancer

Candida oesphagitis

Reflux oesophagitis

Varices

Barretts

A

Reflux oesophagitis

Thickened and irregular oesophageal mucosal folds, ulcers/erosions, strictures and a reticular pattern if associated Barretts

564
Q

Portal Hypertension does not cause

Splenomegaly

Ascites

Ischaemic hepatitis

Thrombocytopenia

A

Ischaemic hepatitis
- Possibly true - could potentially precipitate ischaemic hepatitis

Thrombocytopenia
- Possibly true, due to hypersplenism and sequestration
- Aetiology of thrombocytopenia in liver disease may just relate to reduced TPO production

565
Q

Pancreatitis which is most correct

Pseudoaneurysm is a common complication

Pseudocyst has epithelial lining

Infection in acute necrosis is rare

Alcohol is more related to chronic than acute pancreatitis

A

Alcohol is more related to chronic than acute pancreatitis - biggest risk factor

566
Q

Neonate has deranged LFTs, small GB, echogenic cord at the porta

Biliary atresia

Alagille syndrome

Hepatitis

A

Biliary atresia

567
Q

t/f Oncocytoma has a central scar in 75%

A

false
Central stellate or non-enhancing scar is seen in 1/3 of cases.

Associated with Birt-Hogg- Dube syndrome and TS.

Typically a ‘spoke-wheel’ pattern on angio.

568
Q

 Which of the following breast lesions increases the future risk of breast cancer by the most

Radial scar

Breast apocrine metaplasia

Maybe adenosis?

Fibroadenoma

Cyst

A

radial scar

569
Q

 Which is not associated with ACL tear

Medial meniscal posterior root tear

Lateral meniscal tear

Meniscocapsular separation

Iliotibial band avulsion

Marrow oedema posteromedial tibial plateau

A

Marrow oedema posteromedial tibial plateau

Classic contusion pattern is posterolateral tibial plateau and mid-part of lateral femoral condyle 

570
Q

t/f pivot shift causes pcl tear

A

false. most common mech is anterior force to proximal tibia with knee in flexion

571
Q

TTTS grading

A

Graded by the Quintero staging:

I – oligo / polyhydramnios

II – bladder not visible in donor twin

III – abnormal Dopplers in either twin

IV – hydrops

V – in-utero death

572
Q

Woman with breast implants has a palpable mass, most sensitive test to exclude cancer

Mammo

US

MRI

FNA (it said FNA not core)

A

MRI

573
Q

Radial Scar

Mammo often normal

US often normal

MRI often normal

Spiculations and central density

A

US often normal

Can be sonographically occult

574
Q

DCIS

Mass like enhancement on MRI

Changes often extend beyond macroscopically evident extent

Well circumscribed linear 2mm calcifications

A

Changes often extend beyond macroscopically evident extent

575
Q

 Chondroid tumours in bone

Chondrosarcoma and enchondroma can be impossible to distinguish on imaging and path

Maffucci increased risk of sarcomatous change

Olliers is multiple osteochondromas

Chondrosarcoma degeneration in an osteochondroma occurs in the bony stalk

A

Chondrosarcoma and enchondroma can be impossible to distinguish on imaging and path

Factors favouring chondrosarcoma include large size, cortical breach, deep endosteal scalloping, presence of a soft-tissue mass and increased uptake on bone scan.

Chondrosarcoms are also more likely to have pain, be in older patietns and less likely to occur in the hands or feet.

576
Q

Regarding MSK manifestations of SLE, which is false

Erosions

Subluxations

Osteonecrosis

Symmetrical

A

Erosions

577
Q

Which is not associated with chondrocalcinosis

Haemochromatosis

Wilsons

Diabetes

A

Diabetes

The list is:
- Hypercalcaemia / hyperPTH
- Wilson
- Haemochromatosis
- Ochronosis
- Hypothyroidism
- Oxalosis
- Acromegaly
- ? gout ? arthritides

HOGWASH

578
Q

Which does NOT cause splenomegaly

Amyloid

Sarcoid

Thrombocytopaenia

A

Thrombocytopaenia

579
Q

CJD which is false

Variant CJD in younger patients

Inherited, acquired forms 90%

Slowly progressive disease

A

Slowly progressive disease false

It is rapidly progressive with dementia, cerebral atrophy,y myocolonus and death.

MRI shows high signal in basal ganglia, thalamus and cortex with diffusion restriction. The thalamic signal abnormalities ‘hockey stick and pulvinar’ signs in vCJD.

Sporadic form accounts for up to 90% of cases. vCJD is seen in younger patients and is the bovine to human transmission of bovine spongiform enecphelopathy. There is a familial form which accounts for 10% of cases.

580
Q

Man with DM, septal and post septal stranding, opacification in some (but not all) sinuses, hyperattenuating component in maxillary sinus

A

Invasive fungal sinusitis

Favours chronic invasive fungal sinusitis.

This is usually > 12 weeks in duration and usually are immunocompetent or have a milder level of immunocompromise.

Acute fungal sinusitis should NOT show high density content in the sinuses.

Common in those with diabetes, especially ketoacidosis. It is also seen in neutropenic patients and thosewith advanced AIDS.

Zygomycetes classically seen in diabetic patients. Aspergillus more so in neutropenia.

Imaging shows low density mucosal thickening and soft tissue attenuation in the sinuses.

Nasal septal ulceration and bone destruction may be present.

581
Q

Sinonasal Inverted Papilloma associated with

A

SCC

Inverted papillomas mostly seen in men aged 50.

They most commonly occyr on the lateral wall of the nasal cavity, most frequently related to the maxillary ostium +/- the middle turbinate.

Mucocele formation associated is uncommon.

They can undergo malignant transformation, mostly commonly to SCC (10%). Can also transform to adenocarcinoma, mucoepidermoid and verrucous carcinoma.

582
Q

Pulmonary Alveolar Proteinosis is least correct

Congenital is rapidly fatal

Acquired is due to overproduction of protein rich surfactant

Acquired is like an autoimmune disease

Secondary ?something about immunocompromise

Superimposed infection common problem

A

Acquired is due to overproduction of protein rich surfactant

Associated with lipoprotienaceous material filling the alveoli with is PAS +ve

The material is derived from pulmonary surfactant and the disorder is one of surfactant turnover

583
Q

Crazy paving least likely (recall)

RBILD

PCP

PAP

A

RBILD

584
Q

 Long wordy qn implying air embolism- pt has a CT with contrast, large atrial septal defect, seizures soon after. Mx includes all of following except

Maintain oxygenation

Lateral position right side up

Trendelenburg something

Adrenaline

A

Adrenaline

Prevent further air embolism
Fi02 100%
Venous air embolism – place in left lateral decubitus and Trendeleburg position
Arterial – keep flat supine as head down can worsen cerebral oedema
CPR if needed
Advanced techniques including vasopressors

585
Q

Extraventricular obstructive hydrocephalus

TB common cause

NM Ventriculography doesn’t reflux into ventricles

Obstruction at the level of the cerebral aqueduct

A

NM Ventriculography doesn’t reflux into ventricles

586
Q

Infarct in brain what type of necrosis

Liquefactive

Caseous

Coagulative

A

Liquefactive

six type
- Coagulative – most common, seen in infarcts (not in brain), tissue appears firm, cell outlines preserved
- Liquefactive – cerebral infarcts and abscess
- Caseous – soft, cheesy-looking material. Seen in TB and maybe syphilis or certain fungal infections
- Fat – acute pancreatitis
- Fibrinoid necrosis – immune reactions in vessels
- Gangrenous – coagulative necrosis in an ischaemic limb

587
Q

Regarding aneurysmal disease in brain most correct

Anterior choroidal artery often associated with infundibulum

TOF MRA only detects 50% of aneurysms

Fusiform aneurysmal disease is most common in the posterior circulation

Murphy teat something incorrect (wasn’t the real murphy teat definition)

A

Fusiform aneurysmal disease is most common in the posterior circulation

Most common in vertebrobasilar circulation

588
Q

Head injury

Epidural haematoma is related to injury of vein

Children more prone to subdural haemorrhage

A

Children more prone to subdural haemorrhage

maybe 

589
Q

Lymphocytic mastitis false

Soft =

Can look like cancer =

More common in type 1 than type 2 diabetes

A

Can look like cancer

True, can be multicentric and bilateral

590
Q

Reiters arthropathy

Post gastro infection

20-30% HLAB27

A

Post gastro infection

True, enteric of sexually transmitted infection

Commonly yersinia, salmonella, shigella, campylobacter

591
Q

Least likely to cause cirrhosis

Hep a

Hep b

Hep c

Alcohol

NASH

A

Hep a

592
Q

 Gallbladder cancer not correct

Gallstones

Men 4:1

A

B is false, it is more common in women with a F:M ratio of 4:1, usually > 60 years of age.

Mostly related to chronic inflammatory states including cholecystitis, gallstones (70-90%).

Other RF include IBD, FAP, PSC, porcelain gallbladder, fhx, obesity, certain ethnicities, carcinogen exposure.

593
Q

50 yr old Cta contrast in media

Dissection

Mural thrombus

A

Dissection

594
Q

Ankle fracture of medial malleolus only with talar shift, which most likely

Weber a

Weber b

Weber c

Maisonneuve fracture

A

Maisonneuve fracture

Maisonneuve is a fracture of the proximal fibula with an unstable ankle injury (widening of mortise). This can be either ligamentous injury and / or fracture of the medial malleolus. It is caused by pronation and external rotation mechanism.

595
Q

Absent ICA associated with

PHACE Syndrome

Atlanto-occipital assimilation

Sinus pericranii

A

PHACE syndrome

  • Posterior fossa malformations e.g. DW malformation
  • Haemangiomas
  • Arterial anomalies e.g. dysplasia / hypoplasia / absence of intracranial vessels
  • Cardiac anomalies including coaractation
  • Eye / ocular anomalies
596
Q

Uterine fibroids, most correct

Hyperechoic on ultrasound

Fibroids more commonly dystrophic calcification post menopause

A

Fibroids more commonly dystrophic calcification post menopause

They typically involute and can calcify post menopause

597
Q

Woman has US showing hypoechoic unilocular lesion in adnexa measuring 4cm

Serous ovarian tumour can be difficult to distinguish from simple cyst

Inclusion cysts are more common premenopausal

If there are shadowing regions, less likely to be benign

A

Inclusion cysts are more common premenopausal

Serous cystadenomas account for 60% of serous tumours, are bilateral in 15% and usually appear as a unilocular simple cyst with or without small papillary projections.
- They can be difficult to distinguish from simple cysts but are usually larger (approximately 10 cm).

Functional cysts should be smaller and would be more likely at a size of 4 cm.

Inclusion cysts - almost exclusively occur in pre-menopausal women with a history of prior surgery, PID, endometriosis or trauma. Results from entrapment of ovarian fluid contained within peritoneal adhesions. They lack a discrete limiting wall.

Many benign lesions do shadow including a dermoid and those along the fibrothecoma spectrum.

598
Q

Regarding TCC of urinary tract most correct

Most in bladder are papillary

Something about synchronous and metachronous lesion stats

Lesions in ureter are mostly sessile

Renal pelvis mostly sessile

Usually diagnosed at a low stage

A

Most in bladder are papillary
- True, mostly superficial (70-80%), with 20-30% being invasive
- Most superficial lesions are papillary 70%
- The bladder is the most common site of TCC

more commonly papillary, which is lower grade than sessile

599
Q

Guy with previous rectal cancer. Liver lesion on MRI. Signal loss on out of phase images, arterial enhancing. Not retaining contrast on delayed phase

Met

Adenoma

FNH

A

Adenoma

600
Q

PIOPED has a normal category t/f

A

true, normal is no perfusion defects

601
Q

Papilloma on mamm o appearance

Microlobulation

Amorphous calcs

Well defined calcs

A

Microlobulation

602
Q

Intracranial hypotension findings in the spine, which is not true

Meningeal enhancement

High signal posterior to C1 / C2

Fluid collections

Dilated radicular arteries

Prominent venous plexus

A

Dilated radicular arteries

Defined as cerebrospinal fluid (CSF) pressure <6 cm H2O in patients with clinical presentation compatible with intracranial hypotension, namely, postural headache, nausea, vomiting, neck pain, visual and hearing disturbances, and vertigo

Findings include:
- Pachymeningeal enhancement
- Increased venous blood volume
- Distesion of dural venous sinuses
- Pituitary gland enlargement
- Subdural collections
- Diffuse cerebral oedema
- Sagging brainstem and acquired tonsillar ectopia
- Reduced fluid in optic nerve sheath
- Pontomesencephalic angle < 50 degrees

Work up is with:
- MRI brain with contrast
- Speculative epidural blood patch
- MRI spine with FS TS sequences looking for CSF in the epidural space or CT myelography 

603
Q

Paragangliomas

NF2

Carney syndrome

Charcot marie tooth type II

A

Not sure of the exact wording of this question. Paragangliomas are associated with four clinical syndromes:
- von Hippel-Lindau syndrome
- multiple endocrine neoplasia types 2A and 2B
- neurofibromatosis type 1
- Carney-Stratakis syndrome (also carneys triad)

von Hippel-Lindau syndrome and neurofibromatosis type 1 are more commonly associated with phaeochromocytomas

604
Q

 AAA repair leak at neck type

1a

1b

2

3

4

A

1a

605
Q

Cervical lymph node above hyoid, anterior to submandibular gland

1

2

3

4

5

A

1

606
Q

Regarding aspergillosis, which is false?

Haemoptysis is seen in non-invasive aspergillosis

Lucency in on CXR around lesion due to gelatinous exudate

Most commonly involves the lungs.

Can also involve CNS

A

Lucency in on CXR around lesion due to gelatinous exudate

607
Q

Most sensitive to bowel injury on CT // or was this signs of shock bowel?

Free fluid

Thickened and hyperenhancing bowel

Free gas

A

Features of bowel injury include contrast extravasation, free gas, mural haematoma, fluid, abnormal enhancement.

Bowel injury most commonly involves the jejunum near the DJ flexure > ileum > colon

The CT hypoperfusion complex is:
- Small calibre aorta
- Collapsed IVC
- Low density fluid surrounding the IVC ‘halo-sign’
- Thickened bowel loops >3 mm with enhancing walls
- Most commonly involves jejunum
- Shock pancreas – heterogenous enhancement
- Bilateral adrenal hyperenhancement, particularly useful in paediatrics

608
Q

Bladder injury not identified on CT

A

interstitial

An interstitial injury would not be identified. This is also called a subserosal bladder reupture.

Extraperitoneal rupture is most common (85%) followed by intraperitoneal (15%). Other injuries include a bladder contusion or combined rupture.

609
Q

Suprasellar mass with high T1 signal, which is false

Ranthe cleft cyst

Craniopharyngioma

Aneurysm

Pituicytoma

A

Pituicytoma

Ddx for suprasellar mass with high T1 signal
- Macroadenoma with haemorrhage / nerosis
- Craniopharyngioma
- Rathke’s cleft cyst
- Thrombosed aneurysm
- Fat containing lesion including teratoma / dermoid cyst
- Ectopic posterior pituitary

A pituicytoma is a low grade glial tumour found in the neurohypophysis and infundibulum of the pituitary gland.

They are typically t1 isointense, t2 heterogenous with bright contrast enhancement.

610
Q

Petrous apex lesion on MR, T1 and T2 high. No bone remodelling or destruction most likely

a. Cholesterol granuloma

b. Dipole fat

A

could be either

a. Cholesterol granuloma
- Typically expansile, well-marginated and thin the overlying bone
- May cause bony erosion at the petrous apex, mimic an aggressive lesion

b. Dipole fat
- Asymmetric marrow is common - fat intensity on all sequences
- May be the correct answer 

611
Q

Epididymal lesion, 2cm, vascular

Adamantoid tumour

Thrombosed varix

Torted appendix of Morgagni

A

Adamantoid tumour

these are benign, solid extratesticular lesions of the epididymis, tunica vaginalis or spermatic cord. They are the most common extratesticular neoplasm and most common tumour of the epipdidymis. They are more common at the lower pole with a ratio of 4:1. They are usually incidental, unilateral and mostly in males age 20 – 50.

612
Q

Soft Tissue Lesion, low on T2, no calcification and blooming

Giant cell tumour of tendon sheath t/f

A

GCT of the tendon sheath fits this description. Demonstrated as low t1/t2 signal nodules with moderate enhancement. There is a slight female predilection. Can erode bone. Divided into localised or diffuse forms. Ddx include ganglion cyst, PVNS, desmoid tumours and fibromas of tendon sheath.

613
Q

Regarding general pathology

Atrophy is decrease in size by programmed cell death

Hypertrophy is organ enlargement due to increased number of cells

Metaplasia is irreversible change of one differentiated cell type to another

A

Atrophy is decrease in size by programmed cell death

614
Q

Malignant course of the coronary arteries:

Right coronary courses posterior to the aorta

Left coronary artery intra-arterial

Right coronary artery anterior to the pulmonary artery

Non suture occlusion

A

Left coronary artery intra-arterial - left main or LAD arises from right coronary sinus and courses between the ascending aorta and pulmonary arterial trunk

615
Q

Which of the following is least correct?

Dysplasia inevitably leads to malignancy

Metaplasia is change of one cell type to another

Anaplasia is lack of differentiation from normal cell

Pleomorphism…

A

Dysplasia inevitably leads to malignancy

616
Q

CNS infection

Brain abscess leads to coagulative necrosis

Viral meningitis worse than bacterial

HSV1 affects frontal and temporal lobes

Neisseria meningitis affects old people

Tuberculoma is most common CNS manifestation of TB

A

HSV1 affects frontal and temporal lobes

617
Q

3.5 cm multiloculated complex ovarian cystic lesion. Which makes it most likely to be serous?

Similar lesion on other side

Ascites

Calcification

Solid nodules at the periphery

A

Similar lesion on other side

618
Q

Cystic renal lesion. Which most likely makes it malignant

Thick enhancing septa

Calcification

Enhancing solid nodule

A

Enhancing solid nodule

619
Q

Cystic renal lesion. Which most likely makes it malignant

Thick enhancing septa

Calcification

Enhancing solid nodule

A

Enhancing solid nodule

620
Q

Which is T regarding RCC

Papillary lesions are classically cystic

Clear cell difficult to tell from oncocytoma

VHL is associated with chromophobe type

Renal vein invasion has 35% 5 year survival

A

Renal vein invasion has 35% 5 year survival

621
Q

50yo female with cystic pancreatic lesion

Mucinous

Serous macrocyst

Serous microcyst

SPEN

Pseudocyst

A

Mucinous

622
Q

Diarrhea and oesophagitis

Somatostatinoma

VIPoma

Gastrinoma

Insulinoma

Glucagonoma

A

Gastrinoma

623
Q

 Circumferential rectal tumour. CT show no nodes or metastasis. What is the staging?

1

2a

3a

3b

4

A

2a

624
Q

Hypercalcaemia is most associated with which of these?

Long term dialysis - typically hypocalcaemia

Primary osteoporosis

Post menopausal osteoporosis

Gastric ulcer

Diarrhea

A

Gastric ulcer

625
Q

Most likely cause of nodular or diffuse parathyroid enlargement

Chronic renal failure

MEN1

MEN2

A

Chronic renal failure

626
Q
  1. Likely is true?

Somatroph secreting tumour causes Cushing

Microadenoma are mostly nonfunctional

Pituitary carcinoma causes gigantism

Macroadenoma can occur post adreneclectomy

Lactotroph more commonly diagnosed in males because of galactorrhoea

A

Macroadenoma can occur post adreneclectomy

627
Q

Systemic hypertension least likely to be caused by

Recurrent PE

Renal artery stenosis

Combined OCP

Aortic coarctation

Hyperaldosteronism

A

Recurrent PE

628
Q

Warthin’s

Can occur in cervical LN

Epithelial and mesenchymal cells

A

Can occur in cervical LN

629
Q

Radiation safety in kids not true

Overcouch VS undercouch

Removing grid

Multiple attempts may be needed if kids move

Increased dose when changing cones without image hold

Pulsed VS continuous

A

Overcouch VS undercouch

630
Q

Pregnant patient needs CTPA. Least effective in reducing the fetal dose?

Abdominal lead shield

Increased pitch

Lateral scout

Decrease MAS

Limiting scan to exclude upper abdomen

A

Abdominal lead shield

631
Q

Regarding radiation dose in paediatric population which is least true?

Deterministic effects predominate

Organs are more radiosensitive

Organ dose is higher than adults

Multiple non-diagnostic images may be needed as kids move

A

Deterministic effects predominate

632
Q

Cirrhosis is not seen in

Budd Chiari

A1 antitrypsin

Haemochromatosis

Wilson

A

Budd Chiari

633
Q

Which does not cause HCC

Steatohepatitis without cirrhosis

PBC within 10 years

A

Steatohepatitis without cirrhosis

634
Q

Cholangiocarcinoma- true?

50% in CBD

Intra-hepatic has better prognosis than Klatskin

Choledochal cyst in adolescents is a risk factor

A

Intra-hepatic has better prognosis than Klatskin

635
Q

13 yo M with short stature, webbed neck

Turners

Noonan

Edward

Di George

Cru di chat

A

Noonan

Noonan syndrome (NS) is a genetically and phenotypically heterogeneous non-aneuploidic congenital RASopathy. Affected individuals can bear some clinical features similar to that of Turner syndrome.

636
Q

Haemochromatosis F?

Affects 4th and 5th metacarpals (maybe should read 3rd and 4th)

Chondrocalcinosis

Bilateral and symmetrical

Subchondral sclerosis and cyst

More common in females than males

A

More common in females than males

Although the genetic defect is distributed equally among men and women, the iron loss as a result of menstruation is protective, resulting in a clinical male predilection (M:F ~ 2:1).

Radiographic features
- chondrocalcinosis: particularly knees and triangular fibrocartilage
- arthropathy
- symmetrical loss of joint space, subchondral cysts
- close association with CPPD which is often seen concurrently
- most commonly hands (MCP, carpal, PIP) with the characteristic hook like/ beak-like osteophytes projecting from radial ends of 2nd and 3rd metacarpals
- more extensive involvement from the second to the fifth MCP and radial hook-like/drooping osteophytes are more characteristic than in CPPD 3
- can also affect the knee, hip, and elbow
- generalised osteoporosis (~25%) or osteopaenia (~40%)

637
Q

Child with horseshoe kidney and puffy kids

Turners

Prader willi

Di-george

A

Turners

638
Q

Down syndrome is least associated with…

Alzheimer

Secondary biliary cirrhosis

Hirschsprung

Atlanto-axial instability

Acute leukaemia

A

Secondary biliary cirrhosis

639
Q

Which is correct

Anal atresia is most common intestinal atresia

Oesophageal atresia is usually associated trachea-oesophageal fistula

Hirschsprung is associated with Down Syndrome in 50%

A

Oesophageal atresia is usually associated trachea-oesophageal fistula

640
Q

Barium T?

Coeliac increased jejunal folds

Scleroderma thickened folds

Whipple’s get nodular folds mucosa

A

Whipple’s get nodular folds mucosa

641
Q

Which is seen more in UC than Crohns

Creeping fat

Fistula

Fissure

Pseudopolyps

Skip lesions

A

Pseudopolyps

642
Q

Breast lesion with greatest risk of malignancy

Adenosis

PASH

Radial scar

Duct ectasia

Breast cyst

A

Radial scar

643
Q

Phylloides TRUE?

10% recur after resection

Same age group as fibroadenoma

Stromal component causes the metastases

A

Stromal component causes the metastases - It is generally thought that it is the stromal component that becomes malignant

644
Q

Breast- which is most true?

Phylloides 1% are malignant

Phylloides is about 1% of all breast cancers

A

Phylloides is about 1% of all breast cancers

645
Q

VHL least associated with

Pancreatic adenocarcinoma

Hepatic cyst

RCC

Phaeochromocytoma

Cerebellar haemangioblastoma

A

Pancreatic adenocarcinoma

646
Q

 Which is true

Dandy walker has vermian hyperplasia

Chiari 1 invariably associated with hydrocephalus

Chiari 2 asymptomatic

Both chiari associated with syringomyelia

A

Both chiari associated with syringomyelia

647
Q

Neuromyelitis optica. Which one is least involved?

Periaqueductal grey matter

Area postrema

Subpial grey matter

Optic chiasm

Subependymal callosal

A

Subpial grey matter

648
Q

Patient presents with facial hemiparaesis. Which is most likely the cause?

Anterior-inferior cerebellar artery looping course

Restricted diffusion at CP angle

Neurofibroma in hypoglossal canal

Restricted diffusion in 4th ventricle

A

Anterior-inferior cerebellar artery looping course – more classically associated

Restricted diffusion at CP angle – rare with schwannoma

649
Q

True?

NF2 has schwannomas involving acoustic segment of CN8

NF1 has optic nerve schwannomas

Neurofibromas consist of Schwann cells

A

Neurofibromas consist of Schwann cells - Neurofibromas are benign neoplasms composed of Schwann cells and fibroblasts, containing a rich network of collagen fibres.

650
Q

Child with strawberry tongue, cervical LN, non-suppurative conjunctivitis. What is next most appropriate investigation?

CT neck and chest

Echocardiogram

Neck US

Abdominal US

A

Echo

651
Q

20 yo F with night sweats, cervical LN isointense to muscle. CT of the rest of the neck normal

Hodgkin

Metastatic thyroid cancer

Complicated branchial clei cyst

A

Hodgkin

652
Q

Medullary thyroid cancer on biopsy. What is the next most appropriate investigation?

TC99

I131

CT neck

MRI neck

PET-CT

A

CT neck

653
Q

Hot tub lung not seen

Bronchial dilatation

Centrilobular nodules

GGO

Interlobular septal beading

A

Bronchial dilatation

654
Q

COP false?

Large nodules or masses

Centrilobular nodules

Atoll

Subpleural ground glass consolidation

Bronchial dilatation

A

Centrilobular nodules

655
Q

Which is most correct?

PMF has central necrosis

Simple coal workers pneumoconiosis affects lower lobes

Asbestosis plaques has no zonal predilection

Acute silicosis can look like PAP

Macrophages is key for the diagnosis of pneumoconiosis

A

Acute silicosis can look like PAP

656
Q

Which is not a paraneoplastic syndrome of lung cancer

SIADH

Cushing

Limbic encephalitis

Dilated cardiomyopathy

Lambert

A

Dilated cardiomyopathy

657
Q

Regarding lung cancer which is most true?

Asbestos with smoking 5x risk of lung cancer

2pack/day for 20years has 50% risk of lung cancer

Lung cancer seen in never smokers is more likely to have an eGFR muta6on

Passive smoking has 5x risk of lung cancer

A

Lung cancer seen in never smokers is more likely to have an eGFR muta6on

658
Q

Cystic pleural mass extending through intercostal space with adjacent consolidation

Actinomyeces

TB

Cryptococcus

Metastases

Hydatid

A

Actinomyeces

TB

659
Q

Which is most correct?

Strep causes bronchopneumonia

H influenza in kids has indolent cause

Pseudomonas in alcoholics

Klebsiella in haemoptysis

Staph in COPD

A

Klebsiella in haemoptysis

660
Q

Which is false?

Empyema has more than 1000ml

Asbestos bodies not present in pleural plaques

Mesothelioma involves parietal and visceral plaques

A

Empyema has more than 1000ml

661
Q

Mesothelioma which is most true?

Can cause direct mediastional invasion

Presents with metastases commonly

Commonly occurs in asbestosis

Increased risk with smoking

Occurs 5 years after exposure

A

Can cause direct mediastional invasion

662
Q

Wegener’s most involved

Upper airway

Small bowel

Liver

Heart

Skeletal muscle

A

Upper airway

663
Q

Which is most correct?

Takayasu presents as pulseless disease

PAN and haemoptysis

Behcet causes aortitis

A

Takayasu presents as pulseless disease

664
Q

Temporal arteritis T

Pulmonary arteries are rarely affected

Ophthalmic arteries are rarely affected

C-ANCA elevated

Negative biopsy excludes

Rarely causes non-specific systemic symptoms

A

Pulmonary arteries are rarely affected

665
Q

Uncomplicated retrieval endovascular

Goose neck snare

Biopsy forceps

Stent

Microcatheter

A

Goose neck snare

666
Q

Which one is least correct?

Femoral catheter can last several months

Tunneled have less infection

Hickmann line tip should be at junction of right brachiocephalic and SVC

IJV better than subclavian for dialysis

Fibrin sheath treated with thrombolysis

A

Hickmann line tip should be at junction of right brachiocephalic and SVC

667
Q

20yo F with headaches and hypertension. CTA shows renal artery ostia narrowing

FMD

SLE

PAN

GCA

NF

A

NF - NF-1–associated stenoses often occur in patients younger than 50 years, spare the renal artery origin, are long and tapered, and extend into segmental and intrarenal branches

668
Q

Paediatric lines. Which should be repositioned?

UAC at aortic arch

UVC at junction of RA and IVC

ETT 1.5cm above carina

PICC within left brachiocephalic

NGT subdiaphragmatic

A

UAC at aortic arch

669
Q

Renal aneurysms on DSA. Which is least likely the cause?

RCC

IVDU

NF

Transplant

Diabetes

A

diabetes

Aetiology
- Fibromuscular dysplasia (FMD): 35%
- Degenerative aneurysm: 25%
- Vasculitides, e.g. Behcet disease
- Phakomatoses, e.g. tuberous sclerosis, neurofibromatosis
- Intrinsic collagen deficiency, e.g. Marfan syndrome, Ehlers-Danlos syndrome
- Trauma

670
Q

Most correct?

Charcot bouchard at grey-white matter junction

Venous angiomas prone to cause haemorrhage

Amyloid causes basal ganglia haemorrhage

Basilar type saccular aneurysms from atherosclerosis

A

Venous angiomas prone to cause haemorrhage -

Developmental venous anomalies are usually incidental findings.

However, patients can present with intracranial haemorrhage (1-5%). An association has also been described with ischaemic stroke and epilepsy.

671
Q

AAA which is true?

Cystic medial necrosis is a precursor

3-4cm has 1%/year rupture risk

Inflammatory aneurysm in elderly

Atherosclerosis causes ischaemia of wall causing aneurysm

Mycotic aneurysm from direct retroperitoneal spread

A

Cystic medial necrosis is a precursor

672
Q

Which is true

ICA peak systolic is better than ICA:CCA

Renal artery velocity >300 cm/s is normal

If velocity doubles it means 50% stenosis

A

ICA peak systolic is better than ICA:CCA

673
Q

Tetralogy of Fallot. Which is true?

LV hypertrophy

Pulmonary artery small

Right sided trachea

A

Pulmonary artery small
Pulmonary hypoplasia +/- atresia

TOF
- VSD
- RVOTO
- overriding aorta
- late RVH

674
Q

Patient with lifted cardiac apex and systolic murmur- true?

Mitral stenosis

Valve gradient is greater than 50 mmHg

Cusps are not fused

Velocity is less than 2 m/s

Transthoracic echo is good at picking LA appendage thrombus

A

Valve gradient is greater than 50 mmHg

675
Q

20yo young healthy man with retrocardiac density.

Bronchogenic cyst

Oesophageal cyst

Hiatus hernia

Neuroenteric cyst

LA enlargement

A

Bronchogenic cyst

676
Q

Which one is most correct?

RHD is caused by gram negative antigen

Mitral stenosis invariably caused by RHD

Acute IE occurs on previously damaged valve

Subacute IE causes slow disease but bigger vegetation

Non-sterile marantic endocarditis caused by SLE

A

Mitral stenosis invariably caused by RHD

677
Q

Which one is least likely to be caused by a primary cardiac tumour?

Conduction abnormality

Pericardial effusion

Outlet obstruction

Valvular dysfunction

Tumour emboli

A

Pericardial effusion

678
Q

Small aortic arch. Which is not related?

ASD

PDA

Cor triatriatum

VSD

A

Cor triatriatum

679
Q

20yo Asian F presenting with abdominal pain. CT shows a pouch arising from anterior caecum with high density material. Which is most likely?

Appendicitis

Diverticulitis

Crohn

Typhilis

A

Diverticulitis

680
Q

Bone marrow transplant 1 month ago. RLQ pain. CT ceacal thickening with mucosal hyperenhancement with surrounding stranding

Lymphoma

Typhilitis

Malignancy

Diverticulitis

Pseudomembranous colitis

A

Typhilitis

681
Q

Acute appendicitis F

Bacterial overgrowth causes inflammation

Mechanical obstruction

PV thrombosis

Arterial ischaemia

A

Arterial ischaemia

682
Q

Pregnant woman – appendicitis. LEAST LIKELY

Red degeneration of a fibroid can mimic clinical presentation

Haemorrhagic ovarian cysts can mimic clinical presentation

More likely to perforate

Most likely to occur in 3rd trimester

Most common surgery in pregnant women

A

Most likely to occur in 3rd trimester

683
Q

Colorectal cancer. MOST LIKELY

Left sided tumours are much more common than right

Right sided tumours present with fatigue and weakness rather than occult bleeding

70% of FAP get cancer

Perianal tumours metastasize to the liver

A

Left sided tumours are much more common than right

684
Q

Gastric adenocarcinoma

5 year survival rate 15% if it involves coeliac lymph nodes

H. pylori is associated with gastric adenocarcinoma

Rarely arises from adenoma

Presents early because of obstructive symptoms

Most common in Caucasians

A

H. pylori is associated with gastric adenocarcinoma

685
Q

 40 yr old woman. Barium swallow shows 2 cm long segment of nodular mucosal narrowing at T6 lumen to a diameter of 1.1 cm. Sliding hiatus hernia.

Barretts oesophagus

Eosinophilic oesophagitis

Oesophageal spasm

Zenker diverticulum

A

Barretts oesophagus

686
Q

Which is true

Retinoblastoma is most commonly bilateral

Uveal melanoma metastasizes to the liver

Neurofibroma of the optic nerve

Orbital lymphoma most commonly Hodgkins

A

Uveal melanoma metastasizes to the liver

687
Q

Melanoma – which is most TRUE

Vertical growth occurs before radial growth

Sentinel node biopsy is most important for prognosis

100% of dysplastic naevi get melanoma before age 60

Distant metastases occur first

50% hereditary

A

Sentinel node biopsy is most important for prognosis

688
Q

Second most common location of hydatid after liver

a. Brain

b. Lung

c. Spleen

d. Kidney

e. Heart

A

Lung

Hydatid disease
- Hydatid cysts result from infection by the Echinococcus tapeworm species and can result in cyst formation anywhere in the body.

There are two main species of the Echinococcus tapeworm:
- Echinococcus granulosus - more common
- pastoral: the dog is the main host; most common form
- sylvatic: the wolf is the main host
- Echinococcus alveolaris/multilocularis - less common but more invasive
- fox is the main host

Definitive hosts are carnivores (e.g. dogs, foxes, cats), and the intermediate hosts are most commonly sheep. Humans are accidental hosts, and the infection occurs by ingesting food contaminated with Echinococcus eggs.

Cyst structure
The cysts usually have three components:
- pericyst: composed of inflammatory tissue of host origin
- exocyst
- endocyst: scolices (the larval stage of the parasite) and the laminated membrane are produced here

Location
- hepatic hydatid infection: most common organ (76% of cases)
- pulmonary hydatid infection: second most common organ (15% of cases)
- splenic hydatid infection: third most common organ (5% of cases)
- cerebral hydatid infection
- spinal hydatid infection
- retroperitoneal hydatid infection
- renal hydatid infection
- musculoskeletal hydatid infection
- mediastinal hydatid infection (very rare)

Markers
- Casoni skin test

689
Q

Which is the most likely to cause splenic infarcts

Alpha thalassaemia

Beta thalassaemia

G6PD

Sickle cell anaemia

Myelofibrosis

A

Sickle cell anaemia

690
Q

Splenomegaly. TRUE.

Right heart failure causes massive splenomegaly

Chronic splenomegaly is more prone to rupture

Congestive is the most common cause of hypersplenism

Myelofibrosis is the most common cause of splenomegaly

A

Congestive is the most common cause of hypersplenism

691
Q

With regards to cirrhosis, which is most true?

Fibrosis in cirrhosis is rarely reversible

Ruptured oesophageal varices has a 30% risk of mortality

Hepatitis D superinfection causes decompensa6on in chronic Hepatitis B

A

Hepatitis D superinfection causes decompensa6on in chronic Hepatitis B

692
Q

Pseudogout aspirated joint – what will you see under the microscope.

Negatively birefringent crystals

Positively birefringent crystals

Gram positive cocci

Gram negative cocci

Some other bacteria

A

Positively birefringent crystals

693
Q

Renal stones – associations. MOST TRUE?

Staghorn stones and infection

Uric acid stones are invariably associated with hyperuricaemia

Cysteine stones are associated with increased urine pH

Calcium stones in 50% of people with hypercalcaemia

A

Staghorn stones and infection

694
Q

Renal stones MOST TRUE

Calcium oxalate stones are 30% of stones

Proteus causes struvite

A

Proteus causes struvite

695
Q

Which of the following commonly causes partial ventral cord syndrome?

Syphillis

Acute spinal cord infarct

Vitamin B12 deficiency

Hyperextension injury

Dural mets

A

Acute spinal cord infarct

Ventral cord syndrome (also known as anterior cord syndrome) is one of the incomplete cord syndromes and affects the anterior parts of the cord resulting in a pattern of neurological dysfunction dominated by motor paralysis and loss of pain, temperature and autonomic function.

Anterior spinal artery ischaemia is the most common cause.

696
Q

MSK Tb – LEAST LIKELY

Extraosseous extension is common

Immunocompetent patients have multifocal involvement

Septic arthritis in knees and hips

Pyogenic osteomyelitis is more likely to involve the disc than Tb osteomyelitis

Most common in the thoracolumbar spine

A

Immunocompetent patients have multifocal involvement

697
Q

Charcot spine (least correct)

Neurosyphillis is the most common cause

Destruction of entire vertebral level

Deep sensation and proprioception loss

Differential diagnosis is infection and adjacent segment disease

Increased sclerosis and fragmentation

A

Neurosyphillis is the most common cause

698
Q

Osteomyelitis. TRUE?

In adults the most common is direct spread from adjacent osteomyelitis

Osteomyelitis - 50% have negative blood cultures

S. aureus most common in neonates

Sequestrum is vital rim of tissue surrounding the necrotic dead, infected bone

A

Osteomyelitis - 50% have negative blood cultures

699
Q

Hydroxyapatite deposition disease TRUE?

Linear articular calcification

Amorphous intra-articular calcification

Focal periarticular calcification

Periarticular erosions

A

Focal periarticular calcification

700
Q

AVN hip TRUE?

MRI is more sensitive than bone scan

Changes commonly occur on both sides of the joint

Posterior more common than anterior femoral head

Subchondral lucency on X-ray is common early

Cartilage loss early on - no

A

MRI is more sensitive than bone scan

Classification

stage 0
- plain radiograph: normal
- MRI: normal
- clinical symptoms: nil

stage I
- plain radiograph: normal or minor osteopenia
- MRI: oedema
- bone scan: increased uptake
- clinical symptoms: pain typically in the groin

stage II
- plain radiograph: mixed osteopenia and/or sclerosis and/or subchondral cysts, without any subchondral lucency (crescent sign: see below)
- MRI: geographic defect
- bone scan: increased uptake
- clinical symptoms: pain and stiffness

stage III
- plain radiograph: crescent sign and eventual cortical collapse
- MRI: same as plain radiograph
- clinical symptoms: pain and stiffness +/- radiation to knee and limp

stage IV
- plain radiograph: end-stage with evidence of secondary degenerative change
- MRI: same as plain radiograph
- clinical symptoms: pain and limp

701
Q

AIIS avulsion in young hurdler TRUE?

Hamstrings

Sartorius

Rectus femoris

Iliopsoas

A

Rectus femoris

702
Q

Regarding enchondromas and chondrosarcomas? REPEAT

Child with chondroid tumour in phalanx with invasive component likely chondrosarcoma -

Invasive infiltration of the bone marrow spaces is not a characteristic of benign enchondromas, and this is probably the most helpful microscopic feature in distinguishing an enchondroma from a low-grade chondrosarcoma.

50 yo well defined ileum lesion enchondroma

Diaphyseal eclasia presents with multiple enchondromas

Enchondroma and chondrosarcoma can be similar radiologically and histologically

A

Child with chondroid tumour in phalanx with invasive component likely chondrosarcoma -

Invasive infiltration of the bone marrow spaces is not a characteristic of benign enchondromas, and this is probably the most helpful microscopic feature in distinguishing an enchondroma from a low-grade chondrosarcoma.

also Enchondroma and chondrosarcoma can be similar radiologically and histologically

703
Q

Regarding achilles tendon which is most true?

Concave anteriorly

Tears at calcaneal attachment

Chronic tendinopathy results atrophy

Foci of PD increase signal within tendon can be normal

Fluid within Achilles sheath is always abnormal

A

Foci of PD increase signal within tendon can be normal

704
Q

What is most true

Subscap tear + long head biceps tear

AP radiograph best for subacromial spur

A

Subscap tear + long head biceps tear

705
Q

What is most true

US alone appropriate for painful arc

Even if us characterises tear need mr

US can diagnose frozen shoulder

Long head of biceps subluxes laterally

Supra tear greater tuberosity

Supra articular> bursal

Acute tears echogenic

Bursitis causes cartilage sign

A

US can diagnose frozen shoulder -

Rotator cuff interval capsule can be identified by ultrasound. A thickened rotator cuff interval capsule (≥2.8 mm) is suggestive of frozen shoulder.

706
Q

30 year old woman. Painful lesion arising from just inferior to the lesser trochanter predominantly calcified with a lucent center, saucerisation, with an intact femoral cortex. Bone scan low level uptake of the cortex.

Periosteal chondroma

Osteochondroma

Parosteal osteosarcoma

Lymphoma

Met

A

Periosteal chondroma

707
Q

Woman, medial femoral condyle high signal, cartilage intact. MOST LIKELY

Osteochondral defect

Insufficiency fracture

Grade V bone bruise

Osteochondritis dissecans

Subchondral insufficiency fracture

A

Osteochondral defect

708
Q

ACL tear – LEAST likely associated

Medical meniscal tear

Lateral meniscal tear

Segond fracture

MCL tear

Anteromedial femoral condyle bone oedema

A

Anteromedial femoral condyle bone oedema – usually lateral

The O’Donoghue unhappy triad comprises three types of soft tissue injury that frequently tend to occur simultaneously in knee injuries. O’Donoghue described the injuries as:
- anterior cruciate ligament tear
- medial collateral ligament injury
- medial meniscal tear (lateral compartment bone bruise)

709
Q

Unicameral bone cyst TRUE?

Intramedullary

Fluid-fluid levels on MRI

Femoral is more common than humeral

A

Intramedullary

710
Q

Fibrous cortical defect

Pathological fracture most common presentation

Most commonly occurs in children

Proximal femoral metaphysis

Moth eaten appearance

A

Most commonly occurs in children

711
Q

Rheumatoid arthritis TRUE?

Cell-mediated type 4

Rheumatoid nodules in 25%

Amyloidosis in 50%

Vasculitis affects medium sized arteries

RF positive in JRA – Yes positive in some

A

Rheumatoid nodules in 25%

Rheumatoid nodules are common in RA and appear in approximately 25% of patients.

Rheumatoid nodules favor subcutaneous tissues at pressure points, such as adjacent to bony protuberances.

712
Q

Pulmonary embolus WHICH IS TRUE?

Large emboli cause chronic cor pulmonale

60% of PE cause infarct

Haemorrhage without infarct in pulmonary emboli affecting medium sized vessels

Most commonly come from splanchnic arteries

A

Haemorrhage without infarct in pulmonary emboli affecting medium sized vessels

713
Q

MVA young male – extravasation of contrast on delayed phase in both extraperitoneal and perineal spaces. Where is the injury?

Bladder base

Bladder dome

Prostatic urethra

Bulbar urethra

Urogenital diaphragm

A

Urogenital diaphragm - membranous urethra

714
Q

20 year old man binge drinking, blood stained vomitus, pain on swallowing. Barium swallow normal.

Mallory Weiss

Boerhaeves

Reflux oesophagitis

A

Mallory Weiss

Mucosal and submucosal tear with involvement of the venous plexus

715
Q

50 year old woman, chronic umbilical discharge. CT shows mass adjacent and superior to the bladder.

SCC

Adenocarcinoma

TCC

Lymphoma

A

Adenocarcinoma

716
Q

Bladder TCC what is TRUE?

High grade precursor lesions can be treated with BCG

Flat lesions are better than papillary lesions

Renal pelvis masses are large at presentation

Nodal spread is the strongest prognostic factor

A

Nodal spread is the strongest prognostic factor

717
Q

Prostate cancer TRUE?

Seminal vesicle involvement is M1

Para-aortic nodes have a worse prognosis than pelvic nodes

Never becomes resistant to anti-androgen therapy

Gleason 3+4 = 7 has a better prognosis than Gleason 4+3=7

Transitional zone is 70%

A

Gleason 3+4 = 7 has a better prognosis than Gleason 4+3=7

718
Q

BPH risk factors TRUE?

Diabetes

HTN

Ethnicity

Smoking

Cirrhosis

A

Diabetes
HTN
Ethnicity

Risk factors
- increasing age
- family history
- race: blacks > whites > Asians
- cardiovascular disease
- use of beta-blockers
- metabolic syndrome: diabetes, hypertension, obesity

719
Q

Cervical cancer TRUE?

Caused by HPV 6 & 11

Involvement of vagina is stage IV

Average age of presentation is 70 years old

Mortality is secondary to effects of local invasion

A

Mortality is secondary to effects of local invasion

720
Q

Endometrial cancer TRUE?

Type 1 is associated with atrophy

Type 2 is associated with hyperplasia

Type 1 occurs 10 years later than type 2

20% are type 1

Type 2 has a poorer prognosis

A

Type 2 has a poorer prognosis

721
Q

Gynaecomastia

Associated with lung, pituitary and adrenal tumours

5% risk of malignancy

60% is symmetrical - Gynaecomastia in most cases tends to be unilateral and/or asymmetrical.

Uncommon, only 5% of males over the age of 50

A

Associated with lung, pituitary and adrenal tumours

722
Q

Fat embolism FALSE?

Occurs 1-3 days post injury

Composed primarily of adipose tissue

Lungs oedema and haemorrhage

Commonly presents with petechial skin haemorrhage

Associated with long bone fracture

A

Composed primarily of adipose tissue

723
Q

Highest risk for pancreatic adenocarcinoma

Li Fraumeni

MEN 1

Carney triad

FAP

BRCA2

A

BRCA2

724
Q

Which is not associated with Meig syndrome

Dysgerminoma

Granulosa cell tumour

Brenner

Fibroma

Thecoma

A

Dysgerminoma

725
Q

Ovarian tumours false– possibly 2 questions

Borderline serous tumours are treated with surgery alone

Benign teratomas have a 1% risk of malignant transformation

Ovarian choriocarcinoma has a better prognosis than placental choriocarcinoma

Teratoma is more commonly mixed rather than pure

Choriocarcinoma secretes beta HCG

A

Ovarian choriocarcinoma has a better prognosis than placental choriocarcinoma

726
Q

70 year old male with scrotal mass? MOST LIKELY?

Lymphoma

Seminoma

A

Lymphoma

727
Q

Interstitial pregnancy- which is false?

Pregnancy within the intramural portion of the tube

Not continuous with the endometrial pregnancy

Double decidual reaction

Interstitial line sign is a sign

<5 mm myometrial thickness

A

Double decidual reaction

728
Q

Placental accreteta false?

Placental lacunae are associated

Increta is more common

Previous myomectomy is a risk factor

Indistinction of the endometrium and myometrial junction

A

Previous myomectomy is a risk factor

729
Q

Least likely route of a lesion within the pterygomaxillary fissure

Anteriorly to the maxillary sinus

Through sphenopalatine foramen into nasal cavity

Lateral to temporal fossa

Posteriorly to intracranial

Superior to orbit

A

Anteriorly to the maxillary sinus

730
Q

Medial canthus rim enhancement and erythema, periorbital swelling, cystic

A

dacrocystitis

731
Q

HIV patient with punctate echogenic foci in kidneys with posterior shadowing

HIV nephropathy

PJP nephropathy

CMV

A

PJP nephropathy

CMV

732
Q

Paget’s disease of the bone

Can cause high output cardiac failure

Bimodal age distribution

Predominantly affects osteoclasts

Monoostotic

Bones are soft

A

Can cause high output cardiac failure

733
Q

Gestational trophoblastic disease

Choriocarcinoma can occur months after pregnancy

Complete has maternal and paternal genetic material

Invasive penetrates uterus but does not metastasize

Occurs in young people

A

Choriocarcinoma can occur months after pregnancy

734
Q

Which one is correct?

Achondroplasia has reduced life expectancy

OI type 1 is fatal

Thanatophoric dysplasia die in infancy from multiple fractures

Mucopolysaccharidosis interferes with osteoblasts

Osteopetrosis can be cured with stem cell transplant

A

Osteopetrosis can be cured with stem cell transplant

735
Q

Which is false?

Prion is abnormal protein

Can be sporadic, familial or transmi_ed

CJD tends to occur slowly over years

Variant CJD tends to affect young adults

A

CJD tends to occur slowly over years

736
Q

Which is true?

Lewy body excludes Parkinson’s

Frontotemporal affects >65yo

Huntington causes caudate atrophy

Alzheimer’s spares hippocampus until late

Amyotrophic lateral sclerosis spares cortex

A

Huntington causes caudate atrophy

737
Q

In regards to pregnancy – what is TRUE?

HELLP can cause thrombocytopenia

Eclampsia is ‘something’ – clowng

Fatty liver disease occurs in 1st trimester

Cholangitis is a common complication of cholestasis of pregnancy

A

HELLP can cause thrombocytopenia

738
Q

Emphysema

Paraseptal is a risk factor for pneumothorax

Pneumonectomy causes panlobular emphysema

Alpha 1 anti-trypsin causes compensatory emphysema

Other wrong causes

A

Paraseptal is a risk factor for pneumothorax

739
Q

1 year post pneumonectomy and the mediastinum has returned to the midline – WHAT IS MOST LIKELY?

Normal and common post pneumonectomy

Normal and uncommon post pneumonectomy

Developing post pneumonectomy syndrome

Pleural or local recurrence

A

Pleural or local recurrence

740
Q

Which one is least likely to cause pneumatosis intestinalis?

Cystic fibrosis

Peutz-Jeghers disease

SMA stenosis

MI

A

Peutz-Jeghers disease

741
Q

t/f Beta-catenin mutated hepatic adenomas are associated with malignancy

A

true

742
Q

Chronic renal failure causes which of these conditions most?

Thrombocytopaenia

Polycythaemia

Hypercalcaemia

Hypophosphatasemia

A

Thrombocytopaenia – true

743
Q

Which is most true regarding ovarian tumours?

Brenner is cystic and bilateral

Most common type is germ cell tumour

Mucinous is mostly seen in postmenopausal women

A

Most common type is germ cell tumour

744
Q

Which one of these is least likely to cause craniosynostosis?

Hypothyroidism

Rickets

Previous ventricular drain insertion

Crouzon Syndrome

Thalassaemia

A

Hypothyroidism

745
Q

Patient post op had PE then had IVC filter. Patient had another episode of PE. What is the most likely explanation?

Double IVC

Azygous continuation

Retro-aortic renal vein

A

Double IVC

746
Q

Postmenopausal patient had a breast ultrasound. 1.8 cm new well defined hypoechoic lesion found. Which is most likely?

DCIS

IDC

Phyllodes

Fibroadenoma

A

DCIS

747
Q

Which one is most correct regarding epidural disc migration?

No enhancement

Disc can sequestrate

A

Disc can sequestrate

748
Q

Re: thyroid ca. Which is most true?

Medullary thyroid cancer is a neuroendocrine tumour

Most common type is follicular

Anaplastic is seen in young patients

A

Medullary thyroid cancer is a neuroendocrine tumour

749
Q

Young patient with recurrent chest infection. CT left lung air-trapping, small pulmonary artery and small left lung. What is most likely?

Swyer-James

Pulmonary atresia

A

Swyer-James

750
Q

what is the carpal angle and what cuases increase or decreases

A

Carpal angle is defined by two intersecting lines, one in contact with the proximal surface of the scaphoid and the lunate and the other line through the proximal margins of the triquetrum and the lunate. Its normal value is between 130° and 137°.

It is increased (>139°) in:
- bone dysplasia
- Down syndrome
- Pfeiffer syndrome

It is decreased (<124°) in:
- Hurler syndrome
- Madelung deformity
- Turner syndrome
- Morquio syndrome
- multiple exostoses

751
Q

Whooshing sound in the ear with red mass behind the eardrum. Mass in hypotympanum associated with bony destruction. Most likely?

Cholesteatoma

Glomus tumour

Schwannoma

A

Glomus tumour

752
Q

Regarding doppler US which is most true?

In a fasting patient coeliac artery has low resistance

In a fasting patient SMA has low resistance

A

In a fasting patient coeliac artery has low resistance

753
Q

Regarding dopplers in pregnancy. Which is true?

If the MCA PI is low, then check the ductus venosus waveform

Umbilical artery has high resistance pattern

Doppler of both umbilical arteries should always be checked

UA dopplers are checked twice- if one PI is normal but the other is abnormal, use the normal one.

A

If the MCA PI is low, then check the ductus venosus waveform

754
Q

Young male patient. MRI shows 3 cm high T1, low T2 avidly enhancing renal mass. Which is most likely?

AML

Clear cell renal carcinoma

Haemorrhagic cyst

Proteinaceous cyst

A

AML - Although the detection of fat is a well-established diagnostic imaging feature of classic angiomyolipoma, a hyperattenuating appearance on unenhanced CT and a T2-hypointense appearance at MRI both correspond to the smooth muscle component, are important diagnostic clues to the types of angiomyolipomas that contain few or no fat cells.

755
Q

Shoulder US

Calcific tendinitis best treated conservatively.

US is enough for impingement

Pt with painful abduction- if US is ok then no need for MRI

Acute tear shown as hyperechoic gap

Subscapularis tear is associated with long head of biceps tear

A

Subscapularis tear is associated with long head of biceps tear

756
Q

 Regarding endometriosis. Which is most true?

Presents with bulky uterus

Older patient

Precursor to endometrial malignancy

Presents with an ovarian mass

A

Presents with an ovarian mass - The most common location for endometriotic deposits is in the ovaries. 

endometriomas
- <5 mm: early-stage disease; >15 mm: advanced disease
- shading sign: may be less likely to respond to medical treatment
- low T1 and T2 due to tissue and haemosiderin-laden macrophages

diagnostic criteria:
- multiple cysts with T1 hyperintensity OR
- one or more cysts with high T1 and shading on T2

 haemorrhagic “powder burn”
- lesions appear bright on T1 fat-saturated sequences
- small solid deep lesions
- may be hyperintense on T1 and hypointense on T2

757
Q

Renal cystic disease

Medullary sponge kidney is a disease of childhood

MCDK is associated with lower urinary tract problems

ADPKD has higher risk of RCC

ARPKD juveniles need transplant

Dialysis associated cysts same as simple renal cysts for risk of RCC

A

ADPKD has higher risk of RCC - Patients with ADPKD have a 50x increased risk of renal cell carcinomas, which typically manifest as atypical renal cysts.

758
Q

Which is most true regarding diffusion weighted imaging? REPEAT

Abscess does not show peripheral restricted rim

Intracellular methaemoglobin is low on DWI

A

Intracellular methaemoglobin is low on DWI

759
Q

Bone oedema anterior medial femoral condyle and medial tibial plateau, likely mechanism:

Hyperextension with valgus

Hyperextension with varus

Hyperflexion with valgus

Hyperflexion with varus

Pivot shift

A

Hyperextension with varus

760
Q

Most likely site of intestinal injury in blunt trauma

Duodenum and proximal jejunum

Distal jejunum and ileum

Caecum

Sigmoid colon

A

Duodenum and proximal jejunum

761
Q

Which of the following is LEAST correct regarding diabetic mastopathy?

Dense posterior acoustic shadowing on ultrasound

Lymphadenopathy

Asymmetric density on mammogram

Nonspecific stromal enhancement on MRI

Poorly defined hypoechoic mass on ultrasound

A

Lymphadenopathy

Diabetic mastopathy
- Characterised by the presence of a benign tumour like breast masses in women with long-standing type 1 or type 2 insulin-dependant diabetes mellitus.
- The condition has also been reported in men.
- A similar condition is lymphocytic mastitis but this occurs in non-diabetics.
- It is a form of lymphocytic mastitis and stromal fibrosis. There is dense fibrosis, and predominantly B-cell lymphocytic infiltrate surrounding the ducts, lobules and vessels.
- Appearance:
- Mammography: Asymmetric densities
- Ultrasound: Irregular hypoechoic masses with marked posterior acoustic shadowing

762
Q

What is true regarding MRI safety?

A patient with ferromagnetic ear piercing that they cannot remove is disqualified from entering a 1.5T magnet

A patient with a copper IUD is disqualified from entering a 1.5T magnet

A patient with a cochlear implant is disqualified from entering a 1.5T magnet

A diabetic patient can enter a 1.5T MRI while connected to their external insulin pump

A patient with metallic shrapnel foreign bodies from combat injury is disqualified from entering a 1.5T magnet even if they are far from vital organs

A

A patient with ferromagnetic ear piercing that they cannot remove is disqualified from entering a 1.5T magnet

763
Q

MOST CORRECT in testicular ultrasound

Use a 6mHz linear transducer

Colour Doppler is more sensitive for low flow states than power Doppler

Reversed diastolic flow is normal

Low resistance waveform in intratesticular arteries is normal

A

Low resistance waveform in intratesticular arteries is normal

764
Q

Lady presents with discharge from umbilicus with mass extending from bladder

Adenocarcinoma

Squamous carcinoma

Transitional cell carcinoma

A

Adenocarcinoma

765
Q

Paediatric lateral condyle fracture (something about displaced)– Salter Harris what

I

II

III

IV

A

IV - if type 1 lateral to the groove, II if type 2 - through the groove

766
Q

A (?50) year old male patient has a right pneumonectomy for lung cancer. Follow-up radiographs 1 year later demonstrates return of the mediastinum to the midline.

Normal and common finding

Normal but uncommon finding

Post pneumonectomy syndrome

Local or pleural recurrence

A

Local or pleural recurrence

767
Q

A 9 year old child presenting with abdominal pain, has ultrasound for ? appendicitis. Has a history of treated stage 3 neuroblastoma. The last staging study was performed 3 years ago. Ultrasound demonstrates 3 new low density liver lesions between 1-4cm. Which of the following is most likely?

Neuroblastoma Metastasis

FNH

Adenoma

Haemangiomas

Biliary hamartomas

A

Neuroblastoma Metastasis

768
Q

A 50 year old male presents with fever and right upper quadrant pain 6 months post abdomino-peroneal resection. New 6cm irregular low density lesion in liver with thick enhancing rim. Which is most likely?

Necrotic metastasis

Pyogenic abscess

Amoebic abscess

Hydatid disease

Candidiasis

A

Pyogenic abscess

769
Q

A patient is referred for gadolinium-enhanced MRI for evaluation of a renal lesion. They have a history of type 2 diabetes and an eGFR of 29. Which of the following is the best course of action?

Linear chelate gadolinium

Macrocyclic gad

Non-ionic gad

No contrast

Refer for haemodialysis immediately after the scan and at 24 hours

A

Macrocyclic gad - could be considered
No contrast

770
Q

A patient with a history of prior gastric surgery presents for a Barium swallow. The control image demonstrates surgical clips at the level of the diaphragm. A column of contrast is held up within the oesophagus for 2 minutes. Contrast eventually passes into a loop of small bowel. What surgery have they had?

Bilroth II with afferent limb syndrome

Total gastrectomy with anastomotic stricture

Sleeve gastrectomy with stricture

Slipped gastric band

Unwrapped fundiplication

A

Total gastrectomy with anastomotic stricture

771
Q

11month old presenting with abdominal distension. Midline posterior cranial fossa mass. Renal lesion 10cm. What is the renal lesion most likely?

Wilms

Mesoblastic nephroma

RCC

Clear cell sarcoma

Rhabdoid tumour

A

Rhabdoid tumour- Unlike mesoblastic nephroma, rhabdoid tumors may present with tumors in other tissues including in ~13% of cases, the brain.

too young for wilms, too young for vhl/rcc, sarcoma and nephroma are furphys

772
Q

Least likely in bronchiolitis obliterans

RA

Upper zone predominant

Cystic fibrosis

Seen following lung transplant

Mosaic attenuation in inspiration on HRCT

A

Upper zone predominant

773
Q

A young man presents with pneumonia and is treated with oral antibiotics for 7 days. A follow-up radiograph demonstrates a thin-walled cyst in the lower lobe with air fluid level. What is most likely?

Malignancy

Pulmonary abscess

Pneumatocele

Bronchogenic cyst

Necrotising pneumonia

A

Pneumatocele - thin walled cyst.

Appear within the first week of infection, resolve by week 6. Thin walled cystic spaces within the lung, containing gas.

Little, if any, fluid content favours a pneumatocele

774
Q

Least likely in thoracic outlet obstruction

Elongated transverse process of C6

Cervical rib

Acromioclavicular dislocation

Hyperostosis of the clavicle

First rib ?osteochondroma

A

Elongated transverse process of C6
or maybe First rib ?osteochondroma

775
Q

A CXR of a 20 year old patient shows a retrocardiac density and splaying of the carina. What is the most likely cause?

Bronchogenic cyst

Neurenteric cyst

Left atrial enlargement

Hiatus hernia

Tumour

A

Bronchogenic cyst

776
Q

A young patient presents with a large cystic structure in the right neck. Extension into which of the spaces best distinguishes a ranula from a lymphatic malformation?

Sublingual space

Submandibular space

Parapharyngeal space

Anterior cervical space

Posterior cervical space

A

Sublingual space

777
Q

Marker most associated with T21?

Hypoplastic nasal bone

Aberrant right subclavian artery

Choroid plexus cyst

Single umbilical artery

Echogenic intra-cardiac focus

A

Hypoplastic nasal bone

778
Q

A patient presents with postpartum PV bleeding. Which of the following is most likely?

Bilobed placenta

Succenturiate lobe

Placenta membranacea

Circumvallate placenta

Velamentous cord insertion

A

Succenturiate lobe

779
Q

Which is not a feature of pseudohypoparathyroidism?

Cone shaped epiphyses

Dentate nucleus calcification

Metaphyseal flaring

Early closure of epiphyses

A

Metaphyseal flaring - Erlenmeyer flask deformity

PSEUDOHYPOPARATHYROIDISM
MSK
Short stature, obesity
Brachydactyly
Short metacarpals. Including 4th and 5th
Short metatarsals
Soft tissue calcification
Exostoses

CNS
Basal ganglia calcification
Sclerochoroidal calcification
Deep white matter calcification

780
Q

10 year old follow up MRI for previous medulloblastoma. MRI demonstrates high T1 signal in basal ganglia and thalamus. Most likely cause?

Radiation change

Medulloblastoma metastases

Gadolinium retention

A

Gadolinium retention

781
Q

A young patient presents with headache and ear pain. CT demonstrates smooth expansion of the petrous apex. MRI demonstrates high T1/T2 signal in petrous apex, no enhancement. Most likely cause?

Cholesteatoma

Cholesterol granuloma

Asymmetric normal fatty marrow

Petrous apicitis

A

Cholesterol granuloma (expansile)

782
Q

Which is most likely to be observed in patients with Paget’s disease?

Increased fatty marrow signal on MRI

Lower rate of non-union following fracture

Minimal risk of heterotopic ossification following surgery

Up to 75% of patients are symptomatic at time of diagnosis

Most common in Asians and Africans

A

Increased fatty marrow signal on MRI

783
Q

Young patient (?25yo) presents with a “whooshing” sound. On otoscopy there is a red mass behind the lower half of the tympanic membrane. CT demonstrates permeative lesion involving the middle ear and extending into the jugular fossa. What is the most likely diagnosis?

Haemangioma

Paraganglioma

Metastases

Chondrosarcoma

Dural AVF

A

Paraganglioma

784
Q

40 yr old female with a history of rectal cancer undergoes liver MRI with a hepatocyte specific agent. There is a 1 cm lesion in liver with arterial enhancement and no central scar, no signal loss on out of phase and isointense on delayed (hepatobiliary) phase. Most likely?

FNH

Adenoma

Metastasis

Hemangioma

HCC

A

FNH

785
Q

 Patient with idiopathic intracranial hypotension. Which is not a feature?

Hyperaemia of the pituitary gland

Dural enhancement and subdural collections

Effacement of the chiasmatic cisterns

Leptomeningeal enhancement

A

Leptomeningeal enhancement

Intracranial hypotension
- CSF pressure < 6 cmH2O
Types:
- Primary aka spontaneous
- Secondary: Typically iatrogenic or traumatic

Epi: Middle aged females

Presentation: Positional headache typically. When more significant decreased GCS.

Pathology:
- Monro-Kellie hypothesis is a pressure-volume relationship that aims to keep a dynamic equilibrium among the essential non-compressible components inside the rigid compartment of the skull.
- Spontaneous intracranial hypotension (SIH) usually is the result of a CSF leak in the spine. Causes include:
- spontaneous dural dehiscence of meningeal diverticula (perineural cyst)
- secondary to degenerative dural tears (typically related to calcified thoracic disc protrusions)
- congenital focal absence of dura (nude nerve root) – rare

 Associations:
- Marfan syndrome
- Ehlers-Danlos syndrome (type II)
- autosomal dominant polycystic kidney disease (ADPKD)

 Appearance:
- Described features of intracranial hypotension include:
- subdural collection
- acquired tonsillar ectopia
- dural venous sinus distention

Mnemonic
- S: subdural fluid collections
- E: enhancement of the pachymeninges
- E: engorgement of the venous sinuses
- P: pituitary hyperaemia
- S: sagging brain

786
Q

Which is the least common site to be affected in CRMO?

Thoracic spine

Distal metatarsals

Lateral clavicle

Distal tibial metaphysis

Mandibular condyle

A

Lateral clavicle

Chronic recurrent multifocal osteomyelitis (CRMO)
- Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory bone disorder seen primarily in children and adolescents. There is a female predominance, with 85% of cases reported in women.

Pathology:
- As the condition can be associated with skin conditions, like psoriasis, or inflammatory bowel disease an autoimmune cause is thought likely.

Initially to examine the symptomatic site:
- Early stages: osteolytic lesion
- Later stages: progressive sclerosis

Appearance:
- Typically metaphyseal
- Medial but not lateral clavicular involvement

787
Q

Forearm mass in a 65 yo male, high T1 signal with partial suppression on fat suppression, patchy contrast enhancement. Most likely?

Vascular malformation

Melanoma

Haematoma

Schwannoma

Lipoma

A

Melanoma

788
Q

Which is not a cause of tinnitus?

Small vestibular aqueduct

FMD of the ICA

Paget’s disease

Paraganglioma

Dural AVF

A

Small vestibular aqueduct– large vestibular aqueduct is generally an issue (should be no larger than the posterior semicircular canal).

789
Q

Which is false regarding coalition?

Bilateral in 25%

Talocalcaneal best visualised in coronal plane on CT

Talonavicular is best seen on oblique radiographs

Talar beaking most associated with talocalcaneal

95% are talo-calcaneal or calcaneo-navicular

A

Bilateral in 25%- 50% are bilateral (even if symptomatic only on one side).

790
Q

A patient has disc herniation on MRI. Which is false?

Far lateral L4/5 would impinge L4

Posterolateral L3/4 would impinge L4

Focal herniation is <25% of disc circumference

Broad-based herniation is 25-50%

Annular fissure/tear is traumatic in aetiology

A

Annular fissure/tear is traumatic in aetiology - degenerative

791
Q

Which is false regarding HADD?

Most common in hand

No bony erosion

Periarticular calcification

Can erode into bursae and cause acute inflammation

Commonly incidental in an asymptomatic patient

A

Most common in hand– The shoulder is the most commonly affected joint.

792
Q

ILC – best way to determine local extent?

Tomography and US clearly define ILC

Contrast enhanced MRI

Commonly associated with calcification on mammography

A

Contrast enhanced MRI- Due to its propensity for multicentricity, breast MRI is usually recommended in many countries when histology of a lesion reveals invasive lobular carcinoma.

793
Q

Radial scar which is true?

Most common age 40-60

Commonly associated with lobular breast cancer

Usually / frequently spiculated mass

Presents with calcification on mammogram

A

Most common age 40-60

794
Q

30 year old female with 2 months diarrhoea. Small bowel follow through shows featureless jejunum which is distended to 4cm, and an increased number of ileal folds. What is the most likely diagnosis?

Celiac disease

Scleroderma

Crohn’s disease

A

Celiac disease

Celiac disease, also known as non-tropical sprue, is the most common gluten-related disorder and is a T-cell mediated autoimmune chronic gluten intolerance condition characterized by a loss of villi in the proximal small bowel and gastrointestinal malabsorption (sprue).

Features present on CT enteroclysis may include:
- jejunoileal fold pattern reversal: thought to have the highest specificity is considered the most discriminating independent variable for the diagnosis of uncomplicated celiac disease
- ileal fold thickening
- vascular engorgement
- prominent mesenteric lymph nodes may cavitate with a fluid-fat level
- submucosal fat deposition in long-standing cases
- splenic atrophy

795
Q

Patient with ataxia telangiectasia. Most likely on imaging?

Preserved NAA on MR spectroscopy

No significant white matter change surrounding telangiectasia

Posterior frontal lobe atrophy early feature

SWI is not useful

some option on MIP reformats

A

Preserved NAA on MR spectroscopy

The cerebellar metabolic pattern revealed significantly increased Cho/Cr and reduced NAA/Cho in the A-T patients, implying an increase in the choline signal intensity, with NAA/Cr showing no significant difference from that of the controls.

Ataxia telangiectasia
- Ataxia-telangiectasia is a rare multisystem disorder that carries an autosomal recessive inheritance, sometimes classified as a phakomatosis. It is characterized by multiple telangiectasias, cerebellar ataxia, pulmonary infections, and immunodeficiency.
- On brain imaging, it usually demonstrates vermian atrophy, compensatory enlargement of the fourth ventricle, cerebral infarcts and cerebral hemorrhage secondary to ruptured telangiectatic vessels.

796
Q

Imaging in prion disease / CJD

Bilateral thalamic involvement is pathognomonic for variant CJD (pretty sure this is wrong in retrospect)

DWI changes can precede those on EEG

Early posterior parietal atrophy is an early feature in Heidenhain variant CJD

Abnormal signal intensity is seen in the inferior colliculi in FFI

A

DWI changes can precede those on EEG

797
Q

Proximal jejuno-jejunual intussusception. Which of the following is most likely associated?

Dorsal pancreatic agenesis

Ectopic pancreas

Annular pancreas

Pancreatic divisum

Pancreatic agenesis

A

Ectopic pancreas

Adult intussusception caused by EP represents 5% of all cases of intussusception.

798
Q

Which of the following is not a cause of craniosynostosis?

Thalassemia

Hypothyroidism

Crouzon syndrome

Prior shunt procedure

Rickets

A

Hypothyroidism– hyper but not hypo

Craniosynostosis refers to the premature closure of the cranial sutures. The skull shape then undergoes characteristic changes depending on which suture(s) close early.

Epidemiology: There is a 3:1 male predominance with an overall incidence of 1 in 2000-2500. 8% of cases are syndromic or familial.

Primary forms are either sporadic or familial. Secondary craniosynostosis occurs in relation to a variety of causes:
- endocrine disorders
- hyperthyroidism
- hypophosphataemia
- vitamin D deficiency
- hypercalcaemia
- haematologic disorders causing bone marrow hyperplasia
- sickle cell
- thalassaemia
- inadequate brain growth
- microcephaly
- shunted hydrocephalus

799
Q

A 5 year old child presents with a cough. Obscuration of the right heart border seen on CXR. Most likely cause?

Thymus

RML collapse

Large epicardial fat pad

Pectus carinatum

Ganglioneuroma

A

RML collapse

800
Q

Causes of DECREASED resistive index in kidneys

ATN - increase

Pyelonephritis - increase

Hepatorenal syndrome - increase

Diabetes - increased

Ureteric obstruction - increase

A

The renal arterial resistive index (RI) is a sonographic index of intrarenal arteries defined as (peak systolic velocity - end-diastolic velocity) / peak systolic velocity. The normal range is 0.50-0.70.

Reasons for elevated values
- medical renal disease
- ureteric obstruction
- extreme hypotension
- very young children
- perinephric fluid collection
- abdominal compartment syndrome

Reasons for elevated values in a transplant kidney
- acute tubular necrosis (ATN)
- acute or chronic transplant rejection
- renal vein thrombosis
- drug toxicity
- ureteric obstruction
- perinephric fluid collection

Reasons for decreased values
- renal artery stenosis

801
Q

Complex jaw lesion mandible with centrally rudimentary tooth, surrounding lucency. Displaces adjacent roots away. Most likely?

Ameloblastoma

OKC

Odontogenic cyst

Odontoma

Dentigerous cyst

A

Odontoma

802
Q

A young girl is noted to have a horseshoe kidney on renal ultrasound. The parents remember that she had puffy hands and feet at the time of birth. Which of the following is most likely?

Turners

Noonans

Edwards syndrome

Prader-Willis

A

Turners

803
Q

Which is least likely to be associated with azygos continuation of the IVC?

Dextrocardia

Polysplenia

Gonadal veins draining into ipsilateral renal veins

Left sided SVC

Hepatic veins draining into azygos vein

A

Hepatic veins draining into azygos vein– in azygos continuation hepatic veins usually drain directly in the right atrium.

804
Q

Which is true about para-ovarian cysts?

<1% occurrence

Always unilateral

Can undergo rupture and haemorrhage

Have a small risk of malignancy if complex features

Require annual follow up

A

Can undergo rupture and haemorrhage

Paraovarian cysts are remnants of Wolffian duct in the mesosalpinx that do not arise from the ovary. They account for ~10-20% of adnexal masses.

They usually occur around the broad ligament and arise from paramesonephric, mesothelial, or mesonephric remnants. They are usually simple cysts (although some authors include paraovarian cystadenomas under the umbrella of paraovarian cysts).

Paraovarian cysts occasionally can be complicated by rupture, torsion, or haemorrhage. Large or symptomatic cysts often undergo surgical resection. Smaller asymptomatic ones are treated conservatively.

Given a small chance of representing neoplasm, paraovarian cystic lesions may be recommended for follow-up imaging.

The 2010 Society of Radiologists in Ultrasound consensus statement recommends follow-up of simple paraovarian cysts in situations similar to that of simple ovarian cysts:
- 5-7 cm simple cyst in premenopausal women: yearly ultrasound
- 1-7 cm simple cyst in postmenopausal women: yearly ultrasound
- >7 cm simple cyst in any age: further imaging (e.g., MRI) or surgical evaluation

805
Q

A woman presents with pleuritic chest pain after running a marathon. The chest x-ray is normal. VQ showed “low probability of PE”. What is the next step?

Repeat VQ in 3 months

CTPA

No further imaging required

Quantitative D-Dimer

Lower limb Doppler

A

No further imaging required

806
Q

A lady presents with multiple fractures in the spine, T3,6,7 and 11. Bone scan shows symmetrical and moderately increased uptake at T3 and 7 lesion and physiological uptake elsewhere. Which is true?

T3 and 7 lesions are metastases

T3 and 7 lesions are acute or non-united

All are chronic fractures

A

T3 and 7 lesions are acute or non-united

807
Q

US carotid doppler, which is true?

Ulcerating plaque can be well characterised on Doppler

Origin of the right common carotid cannot be reliably seen on Doppler

Pulse pressure of ICA is more than ECA

Symptomatic plaque is hyperechoic

Intimal thickness should be measured on the anterior wall of the proximal ICA

A

Ulcerating plaque can be well characterised on Doppler– but not always

origin of left not well seen
exa high pulse pressure
tend to be hypo
intimal thickn measure at posterior wall

808
Q

A 60 year old man with recent sore throat and chest pain. CT chest demonstrates a complex cystic pleural lesion which extends through the intercostal space, and an airspace opacity in lower lobe. Most likely?

Pleural metastasis

TB - still the most common cause of empyema necessitans

Cryptococcus

Hydatid

Actinomycosis

A

Actinomycosis
- Aspiration of oropharyngeal/GI secretions into the respiratory tract
- Tends to be lower zones

Empyema necessitans causative organisms:
- Mycobacterium tuberculosis: thought to be most common cause and may account for ~70% of cases
- Actinomyces spp.: considered second most common cause (see: thoracic actinomycocis infection)
- Blastomycosis spp.
- Aspergillus spp.
- Nocardia: see pulmonary nocardiosis
- Mucormycosis spp.
- Fusobacterium spp.

809
Q

CT performed in the setting of trauma. There is a smooth outpouching from the inferior aortic arch at the level of the aortic isthmus. No adjacent haematoma or fat stranding is seen. What is most likely?

Ductus diverticulum

Aortic pseudoaneurysm

Aortic spindle

Traumatic aortic dissection

A

Ductus diverticulum

810
Q

Patient presents with chest pain patient radiating to back. CT shows focal contrast within the media. What is most likely?

Intramural hematoma

Aortic dissection flap

Aneurysm

Aortitis

Ulcerating atheromatous plaque

A

Ulcerating atheromatous plaque - since focal

811
Q

Following a CT scan, a patient complains of moderate forearm swelling and arm pain. Which of the following is appropriate management for IV contrast extravasation?

Immediate review by plastics registrar

Compression bandage, notify the GP and GP review in 1 week

Attempt aspiration, compression bandage, ice and elevation, and regular neurovascular observations

Compression bandage, local anaesthetic cream, elevation

A

Attempt aspiration, compression bandage, ice and elevation, and regular neurovascular observations

812
Q

Screening spine US in neonate. There is a cystic lesion at the distal end of the cord ?filum which slightly splays the cauda equia nerve roots. The conus terminates at a normal level. Next best step?

GA and MRI at 2 years of age

Immediate feed and wrap and MRI

Follow up US at 3 months of age

Immediate paediatric neurosurgical referral

No further imaging required

A

No further imaging required

A filar cyst is an incidental finding on neonatal lumbar sonography located in the filum terminale of the spinal cord.

It is considered a normal variant and is often confused for a ventriculus terminalis, a smooth dilated cavity of the central canal, located within the conus medullaris.

813
Q

A 55 year old man with presents with jaundice and epigastric pain. He has had a cholecystectomy 2 years ago. On ultrasound, the common hepatic duct measures 8mm but the pancreas is not visualised. Liver appears normal. What is the most appropriate next step?

MRI/MRCP

ERCP

AXR

CT

PTC

A

MRI/MRCP

814
Q

Which of the following is true regarding venous infarct? (Context was pretty clearly about intracranial)

Grey and white matter oedema and haemorrhage

Dense cord sign is seen in cortical venous thrombus <5% of cases

Can be associated with hydrocephalus

Dural venous sinus thrombus is directly identified in most cases

A

Grey and white matter oedema and haemorrhage

815
Q

A 20 Asian female patient has a pouch like structure arising from the anterior aspect of the caecum with central echogenic focus. What is the most likely cause?

Acute appendicitis

Caecal diverticulitis

Typhlitis

Epiploic appendagitis

A

Caecal diverticulitis

816
Q

Middle aged male patient with right iliac fossa pain and fever. Area of fat standing posterior to the ascending colon. It has a region of fatty density (-80HU) measuring 3 cm with central small focus measuring 100HU. What is the most likely diagnosis?

Acute appendicitis

Caecal diverticulitis

Typhlitis

Epiploic appendagitis

A

Epiploic appendagitis

817
Q

Fetal echocardiogram. Three vessel view shows:

Aorta, pulmonary artery and SVC from left to right

Aorta diameter is usually larger than pulmonary artery

In Tetralogy of Fallot, the pulmonary artery is significantly smaller than the aorta

A

In Tetralogy of Fallot, the pulmonary artery is significantly smaller than the aorta

818
Q

A patient has an incidental hypoechoic renal lesion which was indeterminate on ultrasound. MRI shows T1 low, T2 high, no enhancement.

Simple renal cyst

Proteinaceous cyst

Hemorrhagic cyst

RCC

AML

A

Simple renal cyst

819
Q

Fibroadenoma appearance in a 40 year old female.

Invariably solitary lesion on US and MMG

Echogenic areas with shadowing on US-

Mass with no enhancement on MRI

If malignancy arises within, it is most likely to be IDC

in premenopausal women classically seen as coarse calcification within a mass on mammo

A

Echogenic areas with shadowing on US- Typically seen as a well-circumscribed, round to ovoid, or macrolobulated mass with generally uniform hypoechogenicity. Intralesional sonographically detectable calcification may be seen in ~10% of cases 2. Sometimes a thin echogenic rim (pseudocapsule) may be seen sonographically.

Fibroadenoma is a common benign breast lesion and results from the excess proliferation of connective tissue. Fibroadenomas characteristically contain both stromal and epithelial cells.

They usually occur in women between the ages of 10 and 40 years. It is the most common breast mass in the adolescent and young adult population. Their peak incidence is between 25 and 40 years. The incidence decreases after 40 years.

The typical presentation is in a woman of reproductive age with a mobile palpable breast lump. Due to their hormonal sensitivity, fibroadenomas commonly enlarge during pregnancy and involute at menopause.

Hence, they rarely present after the age of 40 years.

The lesions are well defined and well-circumscribed clinically and the overlying skin is normal. The lesions are not fixed to the surrounding parenchyma and slip around under the palpating fingers, hence the colloquial term a breast “mouse”.

820
Q

What is DMSA used for?

Cortical scarring in recurrent UTI

Calculation of renal function

Evaluating for renal obstruction

A

Cortical scarring in recurrent UTI

Tc-99m DMSA (2,3 dimercaptosuccinic acid) is a technetium radiopharmaceutical used in renal imaging to evaluate renal structure and morphology, particularly in paediatric imaging for detection of scarring and pyelonephritis.

MAG3 for function.

821
Q

Young female patient presents with a thunderclap headache, orbital pain and diplopia. CT demonstrates nodular thickening of lateral rectus muscle which does NOT enhance. What is the cause?

Idiopathic inflammation (didn’t use the word pseudotumour)

Sarcoid

Metastases

Haematoma

Lymphoproliferative disorder

A

Haematoma

822
Q

Which of the following is most likely to be found in a patient with hemifacial spasm?

Vascular loop of AICA

Pericallosal septal lesion

Diffusion restricting lesion at the CP angle

Frontal lobe mass

Demyelination in the brainstem/pons

A

Vascular loop of AICA

823
Q

A young patient presents with right sided sensorineural hearing loss. There is a past history of haemophilus meningitis. CT demonstrates increased density surrounding the cochlea, vestibule and semicircular canals. Which is most likely?

Labyrinthitis ossificans

Cholesteatoma

Fenestral otosclerosis

Antefenestral otosclerosis

A

Labyrinthitis ossificans– It the depends on the question alternatively retrofenestral/cochlear otosclerosis

824
Q

Lucent, well-defined 4cm lesion in S1 in young adult. What is the most likely diagnosis?

Chordoma

Aneurysmal bone cyst

Giant cell tumour

Metastasis

Ewings

A

Aneurysmal bone cyst

Well defined, lucent

825
Q

A third trimester growth scan demonstrates EFW <5th centile and AC on 20th centile. Which of the following statements is true?

IUGR is more likely than SGA

If MCA PI <5th centile should assess the ductus venosus

Usually see forward flow in a wave in ductus venosus of severely growth restricted foetus

UA doppler should be taken with vessel at right angle to US beam

If UA doppler is normal in one vessel, must do the other vessel also

If UA doppler is normal in one and abnormal in the other, take the abnormal measurement

A

If MCA PI <5th centile should assess the ductus venosus

826
Q

Regarding fetal MCA Doppler.

Measurement is taken > 2cm from MCA origin

The Doppler box should be more than 3mm

Angle correction should be used when Doppler angle is greater than 0

If the PI <5th centile then repositioning and repeat measurement taken

MCA furthest away from the transducer

A

If the PI <5th centile then repositioning and repeat measurement taken

827
Q

Which of the following is true regarding management of contrast reactions?

1:10,000 intramuscular adrenaline is contraindicated

Interlukin 2 reduces the risk of adverse reactions

Hypersensitivity to iodinated contrast is seen in 5% of the general population

Reduced efficacy of adrenaline in patients taking beta-blockers

A

Reduced efficacy of adrenaline in patients taking beta-blockers

828
Q

 Thyroid papillary cancer least correct:

Calcifications within the lesion

Lymph nodes have calcifications

Lymph nodes can show cystic change

Characteristically hypovascular thyroid lesion on US

Hypoechoic thyroid lesion

A

Characteristically hypovascular thyroid lesion on US

829
Q

Which of the following is NOT associated with nasal dermoid?

Nasal cavity mass

Enlarged foramen caecum

Bifid crista galli

Fat/fluid attenuation

Lesion enhancement

A

Lesion enhancement

830
Q

Young female patient presents with hip pain. X-ray demonstrates a lucent lesion below the lesser trochanter of femur, with saucerisation of the femoral cortex. There is a thin rim of cortical uptake on bone scan. Most likely?

Metastasis

Parosteal osteosarcoma

Periosteal chondroma

Chondrosarcoma

Osteochondroma

A

Periosteal chondroma

Juxtacortical chondromas, also known as periosteal chondromas, are rare benign chondral tumours that arise from the periosteum of tubular bones. They are thought to account for ~2% of benign bone tumours.

Plain radiograph
- may be seen as a saucerisation of the adjacent bony cortex with a sclerotic periosteal reaction
- distinct soft tissue mass may be difficult to identify
- matrix calcification may be seen in ~50% of cases; as with all chondroid lesions, this tends to be ring and arc
- most lesions are <3 cm in size

831
Q

Which of the following is commonly associated with diffuse midline glioma?

T2 hyperintense with necrosis and haemorrhage

Avid contrast enhancement

Leptomeningeal infiltration is commonly seen

Invasion of the basilar artery

Most commonly involve the hypothalamus and thoracic cord

A

Leptomeningeal infiltration is commonly seen- Extensive spread is relatively frequent, both craniocaudally to involve the cerebral hemispheres and spinal cord, as well as leptomeningeal spread.

832
Q

 Young male vomiting after binge drinking alcohol. Morning pain and blood stained vomiting. Barium swallow is normal. Most likely

Mallory Weiss tear

Boerhaave syndrome

Reflux oesophagitis

Varices

infection ? candida oesophagitis

A

MWT

833
Q

Young male (?20) with hypertension and bilateral renal artery stenosis (no mention of ostia involvement). On examination has reduced lower [?groin ?femoral] limb pulses. Most likely diagnosis.

Takayasu

Coarctation

Fibromuscular dysplasia

GCA

PAN

A

Takayasu

834
Q

 In regards to spine disease (stem was longer…) on MRI, which is LEAST likely?

Modic II is high T1 and low T2

Modic I is low T1 and high T2

Modic III is low T1 and low T2

Schmorl’s node is herniation of disc into the vertebral endplate

Something about limbus vertebra is an unfused ring hypophysis

A

Modic II is high T1 and low T2 - high, high

835
Q

65 year old female with pancreatic cystic lesion. Demonstrates 2 cysts measuring 3 cm each. No central calcification or scar. Which is most likely?

Mucinous cystic neoplasm

Pauci-cystic serous

Serous cystic neoplasm

SPEN

Adenocarcinoma

A

Serous cystic neoplasm

836
Q

Regarding 2nd branchial cleft cyst. Which is LEAST CORRECT?

Can extend to the supraclavicular region

More common than 1st branchial cleft cyst

Present with otorrhoea

Classically located in the parotid gland

Located posterior to the submandibular gland

A

Classically located in the parotid gland

837
Q

Coronary artery dominance is defined by origin of:

Posterior descending artery

Diagonal arteries

Circumflex arteries

A

Posterior descending artery

838
Q

In trisomy 21 which is the most common atrial septal defect?

Large PFO

Primum ASD

Secondum ASD

Sinus venosus ASD

Unroofed ASD

A

Secondum ASD

839
Q

Small bowel ischemia least likely to present with:

SMA occlusion

IMA occlusion

AAA

AMI

SMV occlusion

A

IMA occlusion

840
Q

Mucinous breast cancer most likely to present as:

Spiculated mass on mammography

Solid lesion within cyst on ultrasound*

Circumscribed mass (?)

Calcification on mammo

A

Circumscribed mass (?)

841
Q

What is false regarding appendicitis in pregnancy (repeat)

More likely to rupture

More common in 3rd trimester

Most common cause of surgical intervention during pregnancy

Differential diagnosis is ovarian torsion

Red fibroid degeneration can be a mimic

A

More common in 3rd trimester– second trimester

842
Q

Most correct option regarding bowel ischemia (least correct)

Acute bowel ischaemia is associated with 60% mortality

SMA occlusion is well tolerated if there are adequate collaterals

Venous ischaemia has less well defined borders than arterial

Hepatic flexure is mostcommon watershed area

A

Hepatic flexure is common watershed area - least correct, splenic flexure

843
Q

Primary haemochromatosis. Least likely involved

Spleen

Liver

Pancreas

Heart

Joints

A

spleen

844
Q

Which is false

SDH mass effect is increased with white matter oedema

Subfalcine herniation is associated with anterior callosal artery infarct

Duret haemorrhage is secondary to tearing of small vessels

Uncal herniation with ipsilateral PCA infarct

Kernohans notch is compression of the ipsilateral peduncle secondary to uncal herniation on the falx

A

Kernohans notch is compression of the ipsilateral peduncle secondary to uncal herniation on the falx

Kernohans notch: indentation in the contralateral cerebral crus by the tentorium cerebelli 

845
Q

Which is an incorrect line placement in neonate ?

Left PICC in left brachiocephalic vein and SVC confluence

NGT below diaphragm

UVC tip at junction of diaphragm and RA

ETT 1.5 cm above the carina

UAC at the level of aortic arch

A

UAC at the level of aortic arch

The tip of the catheter should thus be placed in one of two locations:
1. high position: at T6 to T10 level
2. low position: at L3 to L5 level

846
Q

Least correct regarding vascath placement?

Tunnelled vascath associated with lower infection rate compared with non-tunnelled

Tunnelled femoral vascath can be left in situ for several months

Vascath line tip optimally positioned at brachiocephalic and SVC confluence.

A

Vascath line tip optimally positioned at brachiocephalic and SVC confluence.

847
Q

Patient investigated for infertility issues. Under direct examination there were two uterine cavities and two cervices. Which is the most likely?

Didelphys

Bicornuate

Septat

Unicornuate

A

Bicornuate - could be didelphys but bicorn more likely

848
Q

Which does not cause pneumatosis intestinalis? (TWO questions)

SMA occlusion

MI

COPD

CF

Diverticulosis

A

Diverticulosis

849
Q

Which does not cause pneumatosis intestinalis? (TWO questions)

SMA stenosis

MI

COPD

Asthma

Puetz-Jegher

A

Puetz-Jegher

850
Q

Question about susceptibility-weighted imaging

Sensitive to paramagnetic, diamagnetic and ferromagnetic materials

SWI uses a maximum intensity projection

A

Sensitive to paramagnetic, diamagnetic and ferromagnetic materials

851
Q

65 y.o.female, pancreas cystic lesion; 6cm, has 2x 3cm cyst, DIAGNOSIS

Macrocystic serous

Microcystic serous

Mucinous

Pseudopapillary

A

Macrocystic serous

852
Q

Most correct regarding umbilical artery doppler

Should be measured in a segment of the umbilical cord at 90degrees to the transducer

If two measurements are obtained of UmbA PI, one is normal and one is abnormal, the abnormal result should be reported

PI should be measured in both umbilical arteries, even if the first measurement is normal.

A

Should be measured in a segment of the umbilical cord at 90degrees to the transducer

853
Q

Older patient (60 yo??) with chronic umbilical discharge. CT shows soft tissue mass associated with the umbilicus and bladder dome. Most likely cause

SCC

Adenocarcinoma

TCC

Abscess

A

Adenocarcinoma

854
Q

Most accurate regarding femoral avascular necrosis

Linear lucent band is an early finding on XR

Osseous changes are seen on both sides of the acetabular joint

MRI is more sensitive than TC-99m

A

MRI is more sensitive than TC-99m

855
Q

G1P0 20 something year old with positive beta HCG. Transvaginal ultrasound shows cystic structure in endometrium. No gestational sac or free fluid

MSD measuring 22 mm with an empty sac is a non-viable pregnancy

Not definite for loss, needs repeat ultrasound to assess

A

Not definite for loss, needs repeat ultrasound to assess

856
Q

Nasal dermoid

Doesn’t enhance

Nasal passage lesion

Enlarged foramen caecum

Bifid crista galea

A

Bifid crista galea

857
Q

Papillary thyroid cancer

Calcification

Hypovascuarity

A

Calcification - psammoma bodies

858
Q

 CTA - aortic graft with contrast leak from lumbar artery. Which type

1

2

3

4

A

2

859
Q

Continuation of L SVC. MOST LIKELY drains to

Right atrium

Left atrial appenage

Hemiazygous vein

Coronary sinus.

A

Coronary sinus.

860
Q

1 year old infant with enlarging abdomen/ hepatic origin mass. Has solid and cystic components. AFP is normal for age. What is the MOST likely cause

Mesenchymal hamartoma

Hepatoblastoma

Caroli Disease

HCC

A

Mesenchymal hamartoma

861
Q

Which one of the following is Thoracic outlet syndrome is not seen:

AC dislocation

Elongated transverse process of C6

Cervical rib

Bony callus of the first rib

A

Elongated transverse process of C6 (YES IT SAID C6)

862
Q

Which best describes segment 3 of the liver?

Above the portal vein, between right and middle hepatic vein

Below the portal vein, located left to the left hepatic vein

Above the portal vein, located right to the right hepatic vein

Below the portal vein, between the left and middle hepatic vein

Above the portal vein, between the left and middle hepatic vein

A

Below the portal vein, located left to the left hepatic vein

863
Q

Man found confused. CT demonstrates unilateral thalamic haemorrhage. MRI demonstrates T1 iso, T2 high. Most likely age of the haemorrhage?

Less than 24hrs

1-3 days

3-7 days

7-14 days

More than 14 days

A

Less than 24hrs

864
Q

Neuromyelitis. Least likely finding?

Short segment cord lesions

Bilateral optic nerve involvement

A

Short segment cord lesions

865
Q

Neuromyelitis. Least likely finding?

Short segment cord lesions

Bilateral optic nerve involvement

A

Short segment cord lesions

866
Q

Patient with tinnitis. MRI demonstrates CPA lesion with small cystic components, T2 high signal, peripheral enhancement and restricted diffusion

Dermoid cyst

Schwannoma

Meningioma

Epidermoid

A

Epidermoid - would fit all but for the small cystic components

867
Q

MRI demonstrates high T1/T2 signal in the petrous apex, no enhancement, no expansion. Most likely cause?

Cholesteatoma

Cholesterol granuloma

Normal fatty marrow

Petrous apicitis

A

Normal fatty marrow

Shouldn’t be expansile

868
Q

Diabetic patient with history of nasal obstruction. CT demonstrates orbital stranding, hyperattenuating maxillary sinus lesion. Most likely diagnosis?

Invasive fungal sinusitis

Lymphoma

Allergic sinusitis

Antrochoanal polyp

Inverted papilloma

A

Invasive fungal sinusitis

869
Q

Adult patient presents with a painful eye. CT demonstrates hypoattenuating lesion near the medial canthus with peripheral enhancement. What is the most likely diagnosis?

Dacryocystitis

Dacryoadenitis

Orbital cellulitis

A

Dacryocystitis

Well-circumscribed round lesion with peripheral enhancement around the inner canthus, with adjacent soft tissue thickening and fat stranding

870
Q

Cystic lesion deep to parotid and extending into right parapharyngeal space. Most likely diagnosis?

1st branchial cleft cyst

2nd branchial cleft cyst

3rd branchial cleft cyst

Lymphatic malformation

A

1st branchial cleft cyst

1st branchial cleft:
Above the level of the manidble near the external auditory canal within or close to the parotid

2nd branchial cleft:
Between the angle of the mandible and carotid bifurcation, deeper than platysma and superficial layer of the deep cervical fascia

3rd branchial cleft:
Infrahyoid neck

4th branchial cleft: infrahyoid neck, usually adjacent to the thyroid gland

871
Q

Trauma. Fractures on only one side, involving orbital floor, maxillary sinuses, zygomatic arch. Widening of zygomaticofrontal? sutures.

Tripod

Nasoethmoid

Lefort 1

Lefort 2

Lefort 3

A

Tripod

872
Q

Repeat. Man with back pain following gardening. No focal neurology. Most likely management?

No further imaging

X-ray

CT

MRI

A

No further imaging

873
Q

Most likely cause for lower back and bilateral lower limb pain in a patient with achondroplasia?

Posterior vertebral scalloping

Short pedicles

Small sciatic notches

A

Short pedicles

Achondroplasia
Pelvis and hips:
- Horizontal acetabular roof
- Tombstone/mickey mouse ear iliac wings
- Trigent acetabulum
- Champagne glass pelvic inlet
- Small sacroiliac notches

Spinal:
- Posterior vertebral scalloping
- Progressive decrease in the interpedicular distance in the lumbar spine
- Gibbus
- Short pedicle canal stenosis
- Laminar thickening
- Widening of intervertebral discs
- Increased angle between the sacrum and lumbar spine

Limbs:
- Metaphyseal flaring “trumpet bone” appearance
- Rhizomelic shortening – femora and humeri
- Long fibula – the fibula head is at the level of the tibial plateau
- Bowing to medial segment of legs
- Trident hand
- Chevron sign
- Shortened metacarpals and metatarsals – of similar length

874
Q

Repeat. Most likely location of lesions?

Myxopapillary ependymoma and filum terminale

Central neurocytoma in parietal lobe

DNET in Frontal lobe

A

Myxopapillary ependymoma and filum terminale

875
Q

Repeat. Smoker with shortness of breath. Most likely appearance?

RB ILD

UIP

NSIP

LIP

A

RB ILD

876
Q

Lesion most likely to cause lobar expansion?

Melioidosis

Radiation

COVID 19

Sequestration

Adenocarcinoma

A

Adenocarcinoma

877
Q

Repeat. Coronary artery dominance. Related to which artery?

PDA

Conus branch

Circumflex artery

Diagonal artery

A

PDA

878
Q

Patient with rheumatic heart disease. Next step?

Echo

CT coronary angiogram

MRI cardiac

Non-contrast CT chest

A

Echo

879
Q

Repeat. Patient with hemiplegia. Doppler demonstrates reversal of diastolic flow in ICA. Most likely cause?

CCA occlusion

CCA stenosis

ICA occlusion contralateral

ICA stenosis

A

ICA occlusion contralateral

880
Q

Repeat. Most likely tool to remove foreign body.

Goose neck snare

Forceps

A

Goose neck snare – intended for use in the CVS or hollow viscus to retrieve and manipulate foreign objects

881
Q

Repeat. Patient presents with DVTs and PEs. IVC filter inserted. Represents with new symptoms and is found to have new PEs. What is the most likely explanation?

Duplicated IVC

Azygos continuation of IVC

A

Duplicated IVC

882
Q

45 years old male non smoker with 3 mm nodule in the lung, what to do next?

No follow up

6 month follow up 12 months follow up Biopsy

A

No follow up

883
Q

Repeat. Least likely associated with central scar?

Hepatocellular carcinoma (HCC)

Cholangiocarcinoma

Focal nodular hyperplasia (FNH)

Adenoma

Haemangioma

A

Adenoma

884
Q

Most likely pancreatic variant?

Pancreatic divisum

Annular pancreas

A

Pancreatic divisum - ~5%, most common

885
Q

Pancreatic lesion with arterial phase enhancement, and PV I delayed washout, and hypodense on non con. Which is most likely?

Islet cell tumour

Ductal carcinoma

Adenocarcinoma

Hepatoid carcinoma of the pancreas

A

Islet cell tumour

886
Q

Repeat. Previous gastric surgery. Presents with reflux. Fluoroscopy demonstrates surgical clips at the diaphragmatic hiatus, hold-up of a column of contrast jn oesophagus for 2 min which eventually drains into a loop of bowel.

Unwrapped fundoplication

Sleeve gastrectomy, stricture

Total gastrectomy, anastomotic stricture

Slipped gastric band

Billroth II, afferent loop syndrome

A

Total gastrectomy, anastomotic stricture

887
Q

Man with AIDS. Recurrent Candida infection in oesophagus. Previous oesophageal dilatations 2 years back. Patient had head and neck tumour 18 months earlier which was resected and radiotherapy. Fluoroscopy demonstrates oesophageal thin projections/folds and jet of contrast. Most likely diagnosis?

Oesophageal web

Cricopharyngeal spasm

1ry oesophageal cancer

2ndry metastasis from head and neck

A

Oesophageal web

Associations:
- Plummer-Vinson syndrome
- Graft vs host disease
- GORD
- External beam radiation

“jet effect” of contrast passing distally

Oesophageal constriction caused by a thin mucosal membrane projecting into the lumen

888
Q

Most specific finding of traumatic bowel injury?

Mucosal hyperenhancement.

Submucosal oedema

Pneumatosis

Portal venous gas

A

Submucosal oedema

889
Q

Man presents with right lower quadrant pain. CT demonstrates ovoid lesion adjacent to the ascending colon which is hypoattenuating (-80 HU) and has central hyperattenuating focus (100HU) and adjacent fat stranding. Most likely diagnosis?

Epiploic appendagitis

Appendicitis

Diverticulitis

A

Epiploic appendagitis

890
Q

Best sequence to assess bladder tumour invasion?

T1 without fat saturation

T1 with fat saturation

T2

DWI

A

T2

891
Q

Man from Nigeria.Most likely bladder tumour? (did the stem mention schistosomiasis?)

Adenocarcinoma

Squamous cell carcinoma (SCC)

Transitional cell carcinoma (TCC)

A

Squamous cell carcinoma (SCC)

892
Q

Repeat. 20 year old with well defined lucent lesion in sacrum.

ABC

Giant cell tumour (GCT}

Chordoma

Chondrosarcoma

A

Giant cell tumour (GCT}

893
Q

Chronic shoulder pain. US demonstrates thickening of the supraspinatus muscle, hyperechoic foci in bursal surface with hypoechoic foci more deeply.

Complete tear

HADD

CPPD

Articular surface partial tear

Bursal surface partial tear

A

HADD

894
Q

20 year old patient with enlarging chest wall mass. CT demonstrates rib lesion, right pleural effusion, pulmonary lesions. Most likely diagnosis?

A

Ewing sarcoma

895
Q

Knee pain for weeks. On clinical examination, joint is warm and swollen with decreased ROM. CT demonstrates symmetrical loss of joint space, articular erosions

Infection

Rheumatoid arthritis (RA)

Seronegative arthropath

A

Seronegative arthropathy – for weeks

896
Q

Knee pain. MRI demonstrates lesion in lateral knee, T2 hypointense. CT demonstrates calcification. Most likely diagnosis?

Gouty tophi

Desmoid

Fibroma

PVNS

Giant cell tumour

A

Gouty tophi

Low signal on T1, heterogenous high signal on T2

Only one to have calcification

897
Q

Knee pain. MRI demonstrates lesion in lateral knee, low in T1 and high in T2 with peripheral enhancement. Most likely diagnosis?

A

Cyst

898
Q

Repeat. Runner with shin pain. NM bone scan demonstrates uptake along the posteromedial aspect of the tibia.

Fracture

Medial tibial stress syndrome

Normal

A

Medial tibial stress syndrome:
- Shin splints – stress induced injury
- Periosteal fluid and marrow oedema
- Occurs at the medial surface of the distal 2/3rds of the tibial shaft

899
Q

Repeat. Compressible mass in subcutaneous tissues, plantar aspect, overlying 2nd, 3rd and 4th metatarsal heads. Most likely diagnosis?

Adventitial bursitis

lntermetatarsal bursitis

Plantar fasciitis

Morton neuroma

A

Adventitial bursitis - overlying the metatarsal heads

900
Q

Girl from Tibet? MRI demonstrates (something about suprasellar cistern), mild hydrocephalus, basal enhancement. Most likely diagnosis?

A

tb

901
Q

Repeat. Which is most true regarding juvenile nasopharyngeal angiofibroma?

Males and females equal incidence

Commonly supplied by the internal maxillary artery

Commonly in 20-30 yo

Centred in the anterior nasal cavity

A

Commonly supplied by the internal maxillary artery

902
Q

Chest xray in inspiratory and expiratory phases demonstrates right hilar density, hyperinflation of right lung.

A

Inhaled foreign body

903
Q

Most likely cause of cyanosis on day 2?

A

Delayed closure of ductus arteriosus causing a right to left shunt

904
Q

Repeat. 9 yo girl with abdominal pain. History of neuroblastoma when she was 3. US when she was 7 normal. Now, ultrasound demonstrates multiple new hypoechoic hepatic lesions. Most likely diagnosis?

Neuroblastoma metastases

Multiple FNH

Multiple adenomas

Multiple haemangiomas

A

Neuroblastoma metastases

905
Q

Repeat. What is TRUE about lateral condyle fractures of the humerus?

If non-displaced, considered to be Salter-Harris Type 2

Displacement of <2 mm is associated with a good prognosis

Occurs close to age of physeal closure

A

Displacement of <2 mm is associated with a good prognosis

If non-displaced, considered to be Salter-Harris Type 2 - Depends on the relationship with the trochlear groove
- Type I, lateral to the groove - Salter-Harris 4, stable
- Type 2, through the groove - Salter-Harris 2, unstable

906
Q

Repeat. What is TRUE about a 20 week foetus?

Cisterna magna imaged equally well on coronal as axial

The fornices may be mistaken for cavum septum pellucidum

Cingulate gyrus is usually seen

CSP can’t be seen until 24 weeks

Head circumference is measured on the outer edge of the skull including the soft tissues

A

The fornices may be mistaken for cavum septum pellucidum

CSP can’t be seen until 24 weeks - false, <18 weeks - >37 weeks

907
Q

Pregnant woman presents with PV bleeding. US demonstrates an anechoic lesion with septations in the retroplacental region. Most likely diagnosis?

Placental abruption

Placenta accreta

Placental lake

A

Placental lake

908
Q

Premenopausal woman with simple 2.5 cm paraovarian cyst. Most likely management?

Follow up

No follow up

A

No follow up

909
Q

12 year old girl with a unilateral palpable breast lump. Most likely diagnosis?

Normal breast lump

Fibroadenoma

A

Normal breast lump

910
Q

30-40 year old woman with fibroadenoma. Most likely appearance?

Mammo - ovoid lesion with coarse calcifications

Mammo - ovoid lesion with fine calcifications

US – hyperechoic

MRI - delayed and persistent mass like enhancement

A

MRI - delayed and persistent mass like enhancement

Variable, but most show persistent delayed enhancement

911
Q

Most likely associated with diabetes?

Mastopathy

PASH

A

Mastopathy

912
Q

Woman with previous mammogram overseas which demonstrates calcifications. Told they were “OK”. Mammogram demonstrates pleomorphic calcifications of varying size and shape. Next step?

Biopsy

Further work up

Short term imaging follow up

Return to routine screening

A

Further work up

913
Q

Contrast reaction. Dose of adrenaline?

1:100 IM in 0.5 ml

1:100 IM in 2 ml

1:1000 IM in 0.5 ml IM

1:1000 IM in 2 ml

A

1:1000 IM in 0.5 ml IM

914
Q

Patient on peritoneal dialysis. Requires MRI with intravenous contrast. Next step?

Contrast is contraindicated

Withhold dialysis until after MRI

Intravenous hydration prior to contrast administration

It’s ok to proceed unless diabetic

A

Contrast is contraindicated

915
Q

A HRCT chest in a 45yo female demonstrates patchy bilateral ground glass opacities with surrounding smooth interlobular septal thickening. Which of the following is least likely to be the underlying cause?

Pulmonary haemorrhage

Subacute hypersensitivity pneumonitis

Pulmonary alveolar proteinosis

Pneumocystis jiroveci infection

Acute pulmonary oedema 

A

Subacute hypersensitivity pneumonitis (least likely, all others are established causes of crazy pavy- see Webb, STATDx)

916
Q

A CXR performed in a 70yo male who presented with 2 day history of shortness of breath and fever shows RUL consolidation with inferior bulging of the horizontal fissure. Sputum analysis is most likely to show which of the following organisms?

Gram positive cocci

Gram negative cocci

Gram positive bacilli 

Gram negative bacilli

Acid fast bacilli  

A

Gram negative bacilli (most likely Klebsiella pneumonia, clue is bulging fissure- STATDx, Webb)

917
Q

A 50 year old female with multiple myeloma presents with worsening shortness of breath and stridor. A CT scan demonstrates a long segment of nodular soft tissue thickening surrounding the trachea with foci of calcifications and involvement of the posterior tracheal membrane. What is the most likely diagnosis?

Relapsing polychondritis

Sarcoidosis

Amyloidosis

Tuberculosis

Granulomatosis with polyangiitis 

A

Amyloidosis (most likely, nodular thickening and posterior involvement with calcifications typical- STATDx, Webb)

918
Q

A 25 yo tennis player has an MRI of the shoulder due to worsening shoulder pain. The referring doctor suspects they have internal impingement. Which of the following is least likely to be present?

Supraspinatus tendinosis 

Greater tuberosity cysts

Posterosuperior labral tear  

Infraspinatus articular surface tear

Thickened axillary recess

A

Thickened axillary recess (least likely, more commonly seen in adhesive capsulitis, STATDx, MSK requisites)

919
Q

An elderly patient has a foot x-ray for acute atraumatic heel pain which demonstrates an avulsion fracture of the calcaneal tuberosity. Routine blood tests are most likely to show which abnormality?

Reduced haemoglobin

Elevated HbA1c

Elevated thyroid stimulating hormone 

Reduced thyroid stimulating hormone

Elevated sodium   

A

Elevated HbA1c (most likely, association with diabetes- STATDx)

920
Q

Which of the following stages of neurocysticercosis is associated with the MOST prominent oedema and enhancement on imaging?

Nodular calcified False.

Vesicular

Racemose

Colloidal vesicular

Granular nodular

A

Colloidal vesicular True. Larvae dies an incites an inflammatory response from by the body

921
Q

Which of the following intracranial abnormalities is LEAST likely to demonstrate abnormally increased diffusion restriction?

Cerebral lymphoma

Cerebral abscess

Adenocarcinoma metastasis

Medulloblastoma

Creutzfeldt-Jakob disease

A

Adenocarcinoma metastasis True

922
Q

Which of the following bone lesions is LEAST likely to occur in the metaphysis?

Chondroblastoma

Chondrosarcoma

Osteosarcoma

Osteochondroma

Enchondroma

A

Chondroblastoma True. Occurs almost exclusively in the epiphysis of skeletally immature patients

923
Q

Which of the following locations DOES NOT  form part of the dissemination in space component of the 2017 McDonald criteria for the diagnosis of multiple sclerosis?

Periventricular

Juxtacortical

Optic nerve

Infratentorial

Spinal cord

A

Optic nerve True

924
Q

Which of the following is NOT a sign of idiopathic intracranial hypertension?

Distended optic nerve sheaths

Dural thickening

Partially empty sella

Presence of meningocoeles

Venous sinus stenosis

A

Dural thickening True. A sign of intracranial hypotension

925
Q

Which of the following is LEAST LIKELY to be an imaging feature of gout?

Involvement of the first metatarsophalangeal joint

Preservation of articular cartilage

Reduced bone density

Para-articular erosions

Amorphous soft tissue density

A

Reduced bone density True. Bone density usually preserved

926
Q

Which of the following injuries is LEAST LIKELY to be associated with anterior cruciate ligament tear?

Segond fracture

Posterior cruciate ligament tear

Posterolateral corner injury

Medial collateral ligament tear

Medial meniscus tear

A

Posterior cruciate ligament tear True

927
Q

Which of the following is LEAST LIKELY to be the aetiology of isolated subarachnoid haemorrhage at the vertex?

Dural venous sinus thrombosis

Cerebral amyloid angiopathy

Mycotic aneurysm

Cocaine use

Reversible cerebral vasoconstriction syndrome (RCVS)

A

Cocaine use True. Produces haemorrhages from systemic hypertension or rupture of pre-existing aneurysm (unlikely to occur at the vertex)

928
Q

Which of the following is not a typical feature of autosomal recessive polycystic kidney disease on mid-trimester ultrasound? (US requisites and statdx)

Enlarged fetal kidneys

Hypoechoic fetal kidneys

Oligohydramnios

Pulmonary hypoplasia

Limb contractures

A

Hypoechoic fetal kidneys - kidneys are typically more hyperechoic

929
Q

A woman undergoes a routine second trimester ultrasound at 20 weeks that shows herniation of liver and small bowel through the anterior abdominal wall with a normal length umbilical cord inserted onto the membrane. Which is the most likely diagnosis? (StatDx)

Gastrochisis

Omphalocele

Physiological midgut herniation

Duodenal atresia

Body stalk anomaly

A

Omphalocele

930
Q

A woman undergoes a routine second trimester ultrasound at 20 weeks that shows a monoventricle, fused thalami and a proboscis. What is the most likely associated chromosomal anomaly? (StatDx, ultrasound requisites, alobar holoprosencephaly)

Trisomy 13

Trisomy 18

Trisomy 21

Turner XO

Klinefelter XXY

A

Trisomy 13

931
Q

A 65-year-old man undergoes endovascular aneurysm repair (EVAR) of the infrarenal abdominal aorta. On follow-up CT 1 month later, there is no contrast opacification of the aneurysm sac, however on CT 6 months later there has been expansion of the sac, without contrast opacification. Which is the most appropriate designation?

Type I endoleak

Type II endoleak

Type III endoleak

Type IV endoleak

Type V endoleak

A

Type V endoleak

931
Q

A 39-year-old woman presents for a pelvic ultrasound with symptoms of abdominal pain, distension and nausea. Ultrasound shows bilateral massive ovarian enlargement with numerous enlarged follicular cysts and ascites. What is the most likely diagnosis? (StatDx, ultrasound requisites)

Polycystic ovaries

Polycystic ovarian syndrome

Pelvic inflammatory disease with Fitz-Hugh-Curtis syndrome

Bilateral serous ovarian tumours

Ovarian hyperstimulation syndrome

A

Ovarian hyperstimulation syndrome

932
Q

A 21-year-old female professional rower presents with unilateral arm swelling, pain and venous thrombosis. Digital subtraction venography shows normal flow through the ipsilateral subclavian vein with the arm in a neutral position by her side. Your supervisor suggests repeating the venography with the upper limb in a different position. Which is best? (Paget-Schroeter, statdx, IR books)

Internal rotation

External rotation

Cross-body adduction

Hyperabduction

Extension

A

Hyperabduction

933
Q

Which of the following is not in keeping with the common imaging features of acute pyelonephritis? (StatDX)

Normal ultrasound appearance of the kidney

Wedge-shaped area of hypoenhancement on CT

Small rim of peripheral cortical enhancement on CT

Inflammatory stranding in perinephric fat

Increased T2 signal intensity on MRI

A

Small rim of peripheral cortical enhancement on CT

934
Q

Which is the most common site for deposits in benign metastasising leiomyoma? (StatDX)

Peritoneal

Abdominal lymph nodes

Central nervous system

Retroperitoneum

Lungs

A

Lungs

935
Q

The following statement is false in regards to breast MRI:

Pre-menopausal women should be scanned in the second half of the menstrual cycle

Marked background parenchymal enhancement is associated with a higher likelihood of malignancy. 

Most cancers will show peak enhancement at 60-90 seconds post gadolinium injection.

Lobular cancer can have a Type 1 washout curve. 

Malignancy such as DCIS can be detected as non-mass enhancement. 

A

Pre-menopausal women should be scanned in the second half of the menstrual cycle (FALSE). 

Transiently enhancing lesions can be seen in healthy women in second half of cycle therefore in pre-menopausal women MRI should be performed in first half of menstrual cycle to reduce rate of false positives. 

936
Q

The following are indications for breast MRI except: 

Patient has been diagnosed with metastatic cancer restricted to regional lymph nodes.

Women with a lifetime risk of >20% due to genetics or family history. 

Prior chest wall radiotherapy between ages 10-30. 

Evaluation after removal of silicone breast implants

Pre-operative evaluation in patients diagnosed with invasive lobular cancer. 

A

Evaluation after removal of silicone breast implants (FALSE. Evaluation OF implants but not post removal).  

937
Q

In regards to breast ultrasound, the following statement is true: 

DCIS is more readily detected than mass lesion on second look ultrasound following breast MRI. 

Galactography is more sensitive than ultrasound in detection of  causative lesion for nipple discharge. 

Ultrasound is useful for assessment of chest wall invasion with a sensitivity of 70%. 

Focal zone should be set to the layer of subcutaneous fat. 

Supine is the best patient positioning for assessment of the medial breast

A

Supine is the best patient positioning for assessment of the medial breast

938
Q

The following statement is true in regards to screening mammography: 

Pushback views are only necessary in patients with implants and a palpable lesion.

Increased rate of false positives in younger women

Screening mammography is not performed in women over 75 years of age.

Breast density is an objective evaluation of the amount of fibroglandular tissue

The K-edge of molybdenum used in modern MMG x-ray tubes is approximately 40 keV.

A

Increased rate of false positives in younger women (TRUE). 

939
Q

Which of the  following is the LEAST LIKELY causes for skin thickening on mammography: 

Inflammatory breast cancer. 

Lymphatic obstruction due to metastatic axillary lymphadenopathy. 

Prior chest wall radiotherapy. 

CCF. 

Lactational breast changes. 

A

Lactational breast changes. 

940
Q

In Autosomal recessive polycystic kidney disorder the following are true EXCEPT:

US shows massively enlarged bilateral  kidneys.

Kidneys are diffusely high signal on T2 MRI sequences. 

Cysts are usually > 1 cm in size

Prenatal US may show oligohydramnios. 

Systemic hypertension is seen in 75% patients. 

A

Cysts are usually > 1 cm in size (FALSE usually < 1 cm). 

941
Q

In regards to Ewings sarcoma, which statement is false?

Almost never seen in flat bones

Ewings sarcoma has the highest standard uptake value of malignant primary bone tumours. 

May present as a febrile illness. 

CT is usually performed to assess for lung metastases. 

Is the second most common bone sarcoma in children. 

A

Almost never seen in flat bones (FALSE it 25% percent)

942
Q

The following are causes of dense metaphyseal bands except: 

Growth arrest lines. 

Hypoparathyroidism. 

Congenital infection. 

Rickets. 

Medications such as fluoride and Vit B

A

Medications such as fluoride and Vit B (FALSE its Vitamin D). 

943
Q

In regards to congenital cholesteatoma, which is false? 

More common in males than females. 

Otomastoiditis is a potential complication of larger lesions. 

Rhabdomyosarcoma is a differential for the imaging appearances. 

May have peripheral enhancement on contrast MRI. 

Often fills the entire middle ear cavity

A

Often fills the entire middle ear cavity (FALSE : rarely does).