Headache Flashcards

1
Q

migraine (without aura)

A

*at least 5 attacks, lasting 4-72 hours
*at least 2 pain features: unilateral pain, throbbing pain, moderate-severe intensity, worsens with activity
*at least 1 non-pain feature: nausea and/or vomiting OR photophobia AND phonophobia
*not attributed to another disorder

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2
Q

tension-type headache

A

*30 min-7 days
*bilateral
*steady, pressing, dull (non-pulsating)
*mild to moderate intensity
*no aggravation-routine activity
*NO nausea OR vomiting
*only 1 of photo/phonophobia

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3
Q

migraine WITH aura

A

*reversible neurologic symptoms that usually precede the headache
*visual most common, but can also be sensory/motor/language
*usually lasts minutes, up to an hour
*approx 20% of those with migraines

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4
Q

primary headache syndromes

A

*headaches that do not arise as a result of another underlying disease or medical condition
*tension, migraine, and cluster

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5
Q

allodynia

A

sensitivity to touch with something not normally painful

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6
Q

red flags for headaches

A

SNOOP4:
*systemic symptoms
*neurologic symptoms/signs
*onset sudden
*older age of onset
*postural aggravation
*precipitated by valsalva
*pregnancy
*progressive

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7
Q

cluster headache

A

*at least 5 HA attacks (from one every other day to up to 8 per day)
*severe/very severe
*15 min-3 hours
*unilateral orbital, supraorbital, and/or temporal
*sense of restlessness/agitation
*any of the following conjunctival injection/lacrimation, nasal congestion, eyelid edema, forehead/facial sweating, miosis/ptosis

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8
Q

additional features of cluster headaches

A

*attacks: unilateral face, abrupt; often circadian periodicity (same time of day)
*bouts: circannual periodicity (occur in the same time of the year); triggers: alcohol, REM sleep
*more common in men, similar prevalence to MS

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9
Q

cluster headache treatment

A

abortive:
*SUBCUTANEOUS sumatriptan
*oxygen

stop the cluster bout:
*Galcanezumab
*Verapamil or lithium
*steroids
*occipital nerve blockers

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10
Q

secondary headaches

A

a headache that reflects extracranial or intracranial conditions that may be severe or life-threatening

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11
Q

trigeminal neuralgia

A

*frequent short bursts of pain in the trigeminal distribution (V2 or V3 most common)
*triggers: light touch, air
* > 50 years old

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12
Q

giant cell (temporal) arteritis

A

*caused by granulomatous inflammation of large facial arteries (vasculitis of medium and large vessels in the head)
*age > 55 yo, women
*s/s: headache, bitemporal tenderness, pain with chewing (jaw claudication)
*progresses to blindness
*dx: ESR, CRP, CBC, BIOPSY OF TEMPORAL ARTERY
*start steroids IMMEDIATELY if you suspect it

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13
Q

increased intracranial pressure & secondary headache

A

*s/s: papilledema, awakens in the middle of night, projectile vomiting, cough headache
*causes: brain tumor or high CSF pressure headache

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14
Q

idiopathic intracranial hypertension (pseudotumor cerebri)

A

*overweight women + headache + visual + papilledema
*MRI (exclude brain tumor or venous thrombosis)
*elevated LP opening pressure is diagnostic
*treatment: weight loss, diuretics

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15
Q

low pressure headache / CSF leak

A

*positional headache (laying down good vs sitting up severe)
*most common cause = iatrogenic (from lumbar puncture)
*MRA with contrast: pachymeningeal enhancement
*sagging brain/cerebellum

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16
Q

reversible cerebral vasoconstriction syndrome (RCVS)

A

*recurrent thunderclap headaches
*segmental constriction of cerebral arteries (resolves by about 3 months)
*normal CSF protein
*must rule out subarachnoid blood, CNS vasculitis, cerebral venous thrombosis, cervical artery dissection
*consider precipitants: postpartum, vasoactive drugs, catecholamine tumors

17
Q

thunderclap headache - standard protocol

A

1) head CT (looking for brain bleed)
2) if negative, lumbar puncture (look for blood, infection, and check opening pressure)
3) if negative, consider other causes

18
Q

causes of thunderclap headache

A

*subarachnoid hemorrhage
*meningitis
*CSF leak
*vasculitis
*venous thrombosis
*arterial dissection
*pituitary apoplexy
*RCVS

19
Q

CGRP & migraines

A

*CGRP is a protein released during migraine attacks
*dilates blood vessels, releases inflammatory molecules
*certain tx block the release of CGRP