Heart Failure Flashcards

(52 cards)

1
Q

Systolic Heart Failure heart shape

A

Big, globular, larger volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Diastolic HF heart shape

A

Normal shape, thicker, has problems with eccentric relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

High-Output cardiac failure pathophysiology

A

Peripheral vascular resistance is detected as being lower so the body holds onto more salt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Low-output cardiac failure pathophys

A

Body reads low cardiac output

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drivers of these changes

A

Maintaining MAP for brain and kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cornerstone of therapy

A

Volume control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Can HF get better?

A

Yes, you can take them out of HF.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

New York Heart Association Class

A

Know this for presentations.
Class I: normal exercise tolerance
Class II: symptoms with ordinary exertion
Class III: symptoms with only mild exertion
Class IV: symptom at rest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

EF and disease class relationship

A

There is no association

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ACC/AHA 2001 Guideline for Stages

A

Stage A: High risk (no HF): HTN, CAD, DM, FH of CM
Stage B: Asymptomatic HF: Previous MI, LV systolic dysfunction (no symptoms), asymptomatic valvular disease
Stage C: Symptomatic: Known heart disease, SOB and fatigue, reduced exercise tolerance
Stage D: Refractory end-stage HF: Can’t improve symptoms or can’t sustain improvements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Systolic/Diastolic dysfunction and Staging

A

Both forms of dysfunction follow the same Stages.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Do Stages change?

A

No, once you are Stage C you will always be stage C or worse. The Classes can change, the stages can’t.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Number 1 goal for management

A

Stabilizing patient (symptom relief), then stabilize the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What causes dyspnea

A

Elevated LV end diastolic pressure / PCW pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What causes exercise intolerance

A

Inability to increase cardiac output

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens to SVR during exercise

A

It goes down as muscles fill with blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Fatigue cause

A

Decreased CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What causes edma

A

Increased venous pressure/sodium retention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Neurohormonal activation

A

Sympathetics and Renin-Angiotensin System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Causes of decompensation

A

Infection: 1 degree C increase causes 10-15% increase of O2 consumption
Infarction/Ischemia
Indiscretion: too much salt
Iatrogenesis: NSAIDs effect on kidneys can cause decompensation. CCBs are bad for systolic dysfunction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Narrow pulse pressure means

A

Means diminished stroke volume. Systolic is lower and diastolic is higher because of increased End diastolic volume)

22
Q

Most reliable sign of volume overload

23
Q

Right sided HF signs

A

Elevated JVP, edema, ascites/pulsatile liver, tachy, hypotension with severe disease (low preload)

24
Q

Left sided HF signs

A

Dyspnea, orthopnea, Paroxsymal nocturnal dyspnea, rales, presence of S3, tachy, narrow pulse pressure, hypotension

25
BNP use
Useful in general medicine, can distinguish the heart from the lungs. Not useful in established disease.
26
Most useful diagnostic test
2D echo
27
Where do you biopsy the heart?
The septum to avoid perforation leading to tamponade
28
Why biopsy
Hemochromatosis, amyloidosis, sarcoidosis (infiltrative cardiomyopathies)
29
Giant-cell myocarditis
Auto-immune, elevated troponin with normal arteries
30
Does EF tell you how bad the disease is?
No, no association
31
Volume Status vs. Perfusion
Wet and Warm: Diuretic, Vasodilators Wet and Cold: Inotropes, vasodilators, diuretic Dry and Warm: Optimize chronic medical therapy Dry and Cold: Inotropes Touch the patients to determine if they are warm or cold
32
Measure of perfusion
Mental status, peripheral warmth, cap refill, urine output
33
Measures of Volume Status
JVP, peripheral edema,
34
High afterload on the failing heart
Increased SVR to keep up perfusion hurts the heart in the long run.
35
Vasodilating does what in HF
Decreases afterload, can increase CO.
36
When people are wet can you use vasodilators?
Yes, they have a ton of preload so vasodilating is a good thing
37
How to tell someone is dry
Low JVP
38
How to treat someone who is cold and dry
Inotropes
39
When patients are wet tx
Vasodilators and diuretics, inotropes for Cold
40
How to treat the Stage B patients
Give them beta-blockers and ACEIs to prevent disease progression to symptomatic disease
41
Stage C patients tx
Most patients in the hospital. All patients get ACEI or ARB and Beta blocker, then follow subsequent guidelines
42
Diuretics and natural history
Make you feel better but have no effect on natural history
43
ACEIs and mortality
Reduce death and hospitalizations
44
Beta blockers and mortality
Reverse remodeling and decrease mortality
45
Beta blockers contraindication
Do not give to people who are acutely decompensated, they will go into shock
46
ARBs
Decrease mortality, delay remodeling
47
Digoxin
Symptoms improve, mortality doesn't
48
Spironolactone/Epleronone
Saves lives
49
Hydralizine
Vasodilator
50
Nitrates
Venodilator
51
Cardiac-Resynchronization Therapy for Heart Failure
Synchronizes ventricles to decrease mortality in patients with LBBB. The lead isn't in the Left ventricle, it wraps around the outside
52
Drugs for diastolic HF
There are no drugs, all the drugs are for systolic HF