Helminths Flashcards

(36 cards)

1
Q

Important direct and indirect dis causes as cause

A

Prod limit
Compromise welfare
Can be fatal and zoonotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Helminths living in brain

A

Tapeworm larvae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Blood helminth

A

Flukes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Skin helminths

A

Filarial worms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Small intestine helminths

A

Adult tapeworm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Large intestine helminth

A

Nematodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Muscle helminths

A

Trichinella larvae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Liver helminths

A

Fasciola adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adomasum helmiths

A

Nematodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Lung helminths

A

Lungworms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Feeding

A

Passive eg tapeworm
Browsers eg ascarids
Solid tissue feeders eg strongyle
Blood feeders eg haemonchus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Guts and digestion

A

Nematodes have nouth and anus
Trematodes have mouth that food passes in and out of
Cestodss have no gut absorb nutrients through cuticle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Repro

A

All sexual dioecious (nematodes) monoeicious (trem and cest)
Some can also repro asex
Adults sexually mature found only in defin host
Larvae sex immature and found in int def transport and paratenic host
Eggs usually passed in faeces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Def host

A

Where adult parasite stages dec

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Int host

A

Where immature stages dev in case of indirect lifecycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Transport host

A

Immature stages taken up but not retained and no dev

Not essential for lifecycle

17
Q

Paratenic host

A

Inmature stages retained in host tissue but no dev

Not essential for lifecycle

18
Q

Evolution

A

From free living organisms in O2 starved benthic deposits
Nor highly complex with v pleomorphic genome si can overcome any eradication strategy
Become parasitic as hosts coevolved

19
Q

Nematode morphology

A

Cylinderical tapering at both ends
Body has ridges rings and pther structures
Distinctive head
Epiderm covered by collagenous cuticle
M cells under epiderm projections run towards n cords
M layer around a fluid filled body cavity
Gut at centre of body

20
Q

Nematode feeding

A

Compete with host for nutrients
Either mouth like struct to browse mainly close to muc surf of GIT or specialised cuticular struct eg buccal capsule and stylets to feed directly on host tissue or blood
Have true gut and excretory orifice
Rel inefficient feeders only a small proportion of ingested nutrients used by parasite

21
Q

Nematode repro

A

Dioecious
Spec anatom adaptation to mating
Most adopt r strategy to allow rapid expansion in favourable conditions and residual level maintainance in unfavourable
Nutrients req for high egg no provided by host and esp with digestive inefficiency explains why small no canhave large impact on host

22
Q

GI trichostrongyle nematodes

A

Direct lifecycle
Adults in prediliction site in GIT of final host
Eggs shed in faeces and dev L1 L2 and L3 free living larvae
L1 and 2 feed on bact in faeces
Outer cuticular layer of L2 retained and form protective sheath when moult to L3
L3 cant feed but migrate out of faeces into herbage to be ingested by another defin host (L3 are the infective form) once ingested L3 exsheath and moult to L4 in rumen (abomasal parasites) or abomasum (intestinal parasites)
L4 reach predeliction site and moult to L5 and become adults

23
Q

Prepatent period

A

L3/infective stage to mature adult time
Time taken from infection to adult presence
Determine treatment interval in programmes to suppress faecal output

24
Q

Angiostrongylus vasorum canine heartworm nematodes hists

A

Canid final host to adult (in CV syste)
Terrestrial mollisc int host (key to lifecycle but only larval stages in them)
Amphibian paratenic host

25
Free living nematode enviro conditions
Most teichostrong eggs survive best at 18-26 degrees at higher temp dev is faster but energy rate more quickly depleted so incr mortality rate Eghs dont hatch or larvae dev at temp below 10 Larval dev only when humidity over 80% and optimal at 100 survival low at below 80 in herbage Humidity in grass and faeces allows dev when dry Dessication kills L3
26
Nematode survival stretegy
``` Thick walled enviro res eggs (ascarid) Retention of L2 cuticle sheath on L3 assist harsh enviro survival (trichostrongyle) Arrested dev/hypobiosis Critical egg hatching req Periparturient rise in egg prod ```
27
Arrested dev hypobiosis
Temporary pause in dev in host as evolutionary strategy to survive adverse enviro conditions Physiological- toxocara canis - larvae enter hypobiosis in tissues and are react 3 wk pre parturition and migrate to and infect foetus Seasonal - ostergaia ostertagi - larvae ingested in autumn and overwinter in abomasal gastric glands larval dev resume in spring
28
Crit egg hatching req
Larvae overwinter in eggs Hatch onto pasture in spring after receiving enviro trigger usually temp Allow mass emergence in spring when many suscept hosts around
29
Periparturient ruse
Incr faecal egg count of ewes and goats around parturition Competition between host imm stst and pro req of pregnancy and lactation so arrested larvae mature incr new infect establishment incre female egg output
30
Platy helminthes
``` Cestodes and trematodes Dorso ventr flattened No bidy cavity Organs embedded in solid matrix Monoecious Both sex and asex repro Some trematodes are triploid ```
31
Trematodes - flukes
Unsegmented leaf like One or two suckers for host attachment Blind gut with single opening Indirect lifecyvle with one or two int hosts one of which is always a mollisc
32
Cestodes - tapeworms
Segmented Very ling sometimed Usually have a distinct scolex/head with hooks and or duckers for hist attachment Identical proglotids (segments) continually prod form neck of scolex Proglottids flat white and rectamgles in tape form known as strobila Mature into self cont hermaphroditic egg prod units No gut-nutrients diffuse through cuticle Indirect lifecycle with vert and invert int host
33
helminth host balance
Upset by domestication and intensive farming dev creating enviros that: Suited to dev and survival of free living stages with enganced exposure to infective forms Inadvertantly alter host imm or inn resp Enable exposure to prev unrecog species and strains Can upset sustainable equilibrium between parasote and host Can guve competetive advantage to some allowing them to presominate and be more patjogenic
34
Control
Evasion : low stocking densities on variety of herbage and co grazing or browsing with other animals that are hosts to same parasites Grazing rotation Seldom conducive to economic prod Strategic use of anthelmintics aim to suppress infective larval pop, due to highly pleomorphic genome they will become res Most farms and pet owners etc have become athlemintic dep to maintain productivity and good welfarr Used to strike balance between level of challenge that impairs an animal and that needed to enable protective imm dev
35
Anthelmintic problems
Effect of climatic variation on livestock and helminths Freq stockpvement and quarantine impracticality Sub efficacy of some drug usage Innapripriate timing of administration Effect of concurrent dis or managment on anthelmintic action
36
Important public health concerns
Hook worms and cutaneous larva migrans Ascarid and visceral nematodes Human fasciolosis Exhinococcus tapeworm