Hematology

Question 1

Blood cancer associated with DIC

Answer 1

Acute Promyelocytic Leukemia

Question 2

Microangiopathic Hemolytic Anemia + Thrombocytopenia

Answer 2

Thrombotic Thrombocytopenia Purpura

Question 3

Livido Reticularis + Recurrent miscarriages

Answer 3

APLA Syndrome

Question 4

Elderly with Blood Smear shows Lymphocytosis and Smudge cells

Answer 4

CLL

Question 5

Normocytic Anemia with Sideroblastic change

Answer 5

Lead poisoning

Question 6

Jaundice + cholecystitis + anemia

Answer 6

Hereditary Spherocytosis

Question 7

Hodgkin Lymphoma with best prognosis

Answer 7

Lymphocyte predominant

Question 8

Hodgkin Lymphoma with worst prognosis

Answer 8

Lymphocyte depleted

Question 9

Malaria + Anemia + Increased reticulocyte count + Acute Kidney injury

Answer 9

Blackwater Fever

Question 10

Best way to detect protein c deficiency

Answer 10

Copperhead Snake Venom Assay

Question 11

Protein C inhibits which clotting factors

Answer 11

Factors Va and VIIIa

Question 12

Early Pregnancy blood transfusion extra screening test

Answer 12

Cytomegalovirus

Question 13

Pneumococcal vaccine before splenectomy time

Answer 13

Minimum 14 days before

Question 14

Most common complication of heparin induced thrombocytopenia

Answer 14

Deep Vein Thrombosis

Question 15

Excessive bleedingg following dental extraction

Answer 15

Von-Willebrand’s Disease

Question 16

Cold Agglutinins + Lymphadenopathy + Night Sweats

Answer 16

Non- Hodgkin’s Lymphoma

Question 17

Chemotherapy agents causing Neuropathy

Answer 17

1. Vincristine
2. Cisplatin
3. Paclitaxel

Question 18

What is Mycosis fungoides

Answer 18

Cutaneous T-Cell Lymphoma

Question 18

Anemia + Hypercalcemia + Lower back pain

Answer 18

Multiple Myeloma

Question 19

CLL with anemia investigation to identify cause

Answer 19

Antiglobulin Test (Coombs test)

Question 20

Prophylactic to reduce bleed during procedures in von willebrand disease

Answer 20

DDAVP + Tranexamic Acid

Question 21

Causative Agent of Aplastic Crisis in Sickle Cell Disease

Answer 21

Parvovirus B19

Question 22

Autoantibodies responsible for Heparin-Induced Thrombocytopenia

Answer 22

Anti-heparin-PF4 antibodies.

Question 23

Late complication of Hodgkin Lymphoma after chemo

Answer 23

Secondary Acute Myeloid Leukemia

Question 24

Trephine biopsy showing fatty bone marrow

Answer 24

Aplastic Anemia

Question 25

Aplastic Anemia management

Answer 25

Hematopoetic Stem Cell Transplantation

Question 26

Most common type of Hodgkin's Lymphoma

Answer 26

High Grade B cell Hodgkin's Lymphoma

Question 27

Neck Lump Investigation of choice

Answer 27

Excision Biopsy

Question 28

Acute Myeloid Leukemia gene associated with worst prognosis

Answer 28

Chromosome 7 Abnormality

Question 29

Medicine to reduce risk of acute urate nephropathy in AML

Answer 29

Allopurinol and Rasburicase

Question 30

Nail finding Characteristic of Iron deficiency anemia

Answer 30

Koilonichya

Question 31

First Line Treatment for Chronic Myeloid Leukemia

Answer 31

Imatinib

Question 32

Drug of choice for DVT

Answer 32

Apixaban or Rivaroxaban

Question 33

Urine Dipstick positive for blood + no red cell seen on urine microscopy

Answer 33

Paroxysmal Nocturnal Hemoglobinuria

Question 34

Alteplase reversal Guidelines

Answer 34

FFP + Tranexamic Acid

Question 35

Sickle Cell disease with Low Urine Osmolality

Answer 35

Nephrogenic Diabetes Insipidus

Question 36

Leukemia + pancytopenia + LFT deranged + Diarrhea + Rash

Answer 36

Graft vs Host Disease

Question 37

Nephrotic Syndrome clotting cause

Answer 37

1. Protein S 2. Anti Thrombin

Question 38

Arthritis + Splenomegaly + Neutropenia

Answer 38

Felty's Syndrome

Question 39

Investigation to assess prognosis of Multiple Myeloma

Answer 39

Serum Beta-2 Microglobulin

Question 40

Effective Management of Paroxysmal Nocturnal Hemoglobinuria

Answer 40

Eculizumab

Question 41

Burkitt Lymphoma gene

Answer 41

c-Myc

Question 42

Clinical Features of Primary Antiphospholipid syndrome

Answer 42

1. DVT 2. Livido Reticularis 3. Thrombocytopenia

Question 43

Anemia + Increased Osmotic Fragility

Answer 43

Hereditary Spherocytosis

Question 44

Anemia + Cholecystitis

Answer 44

Hereditary Spherocytosis

Question 45

Essential Thrombocytosis management

Answer 45

Hydroxycarbamide and Aspirin

Question 46

Indication for Fresh Frozen Plasma Transfusion

Answer 46

Increased PT and APTT

Question 47

Indication for Platelet Transfusion

Answer 47

Active Bleeding + Decreased Platelet <50,000

Question 48

Heinz Body seen in

Answer 48

G6PD Deficiency

Question 49

Evan's Syndrome

Answer 49

Autoimmune Hemolytic Anemia and ITP

Question 50

Inherited prothrombotic disorder in Northern Europe

Answer 50

Factor 5 leiden

Question 51

Hairy Cell Leukemia gene affected

Answer 51

BRAF gene

Question 52

Cells with abundant cytoplasm and broad based projections

Answer 52

Hairy Cell Leukemia

Question 53

Acute Intermittent Porphyria Acute Attack management

Answer 53

IV Heme Arginate

Question 54

How to differentiate Acute Intermittent Porphyria and Lead Poisoning

Answer 54

Anemia not seen in Acute Intermittent Porphyria

Question 55

Monotherapy for CLL

Answer 55

Chlorambucil

Question 56

Indication for Use of CEA in cancer patients

Answer 56

For Post op Surveillance

Question 57

EBV Associated Lymphoma and Gene

Answer 57

Burkitt Lymphoma (c-Myc proto-oncogene)

Question 58

Blood picture for Bone Mets cancer

Answer 58

Leukoerythroblastic blood picture

Question 59

Cancer with Cachexia which acute phase marker is elevated

Answer 59

CRP

Question 60

Common presentation of Ovarian cancer

Answer 60

Dermatomyositis (proximal muscle weakness) + bloating

Question 61

Pregnancy with Hypercoagulability

Answer 61

Factor 5 Laiden mutation

Question 62

Normal WBC but Smear shows bilobed nuclei in neutrophils

Answer 62

Pegler-Huet Syndrome

Question 63

AML drug of choice to prevent Acute renal Impairment in Induction chemo

Answer 63

Rasburicase (urate oxidase)

Question 64

Treatment of CLL Chemo regimen

Answer 64

Fludarabine, Cyclophosphamide and Rituximab (FCR)

Question 65

Chemotherapy agent associated with Hypomagnesemia

Answer 65

Cisplatin

Question 66

Highest risk of bacterial contamination when compared to other types of blood products

Answer 66

Platelet transfusions

Question 67

Cancer with Anti-N-methyl D-aspartate (NMDA) Receptor Antibody +ve

Answer 67

Ovarian Teratoma

Question 68

Investigation of choice for CLL

Answer 68

Immunophenotyping