Hematopoiesis Flashcards
(30 cards)
production of all blood cells - continuous process through entire life
hematopoiesis
where does hematopoiesis take place in the fetus
liver and spleen
where does hematopoiesis take place in adults
red bone marrow
less active red bone marrow, mostly fat cells
yellow bone marrow
bone marrow sites in most species
skull
ribs
sternum
vertebrae column
pelvis
proximal ends of femurs
all blood cell types are derived from a single primitive stem cell typed called what
pluripotential or multipotential stem cell
pluripotential or multipotential stem cells have the potential to replicate and differentiate into many different discrete types of what
unipotential stem cell
maturation process where unipotential stem cell matures into specific cells
erythropoesis (RBC)
leukopoiesis (WBC)
thrombopoesis (platelets)
the process by which red blood cells are created
erythropoesis
eventually the erythrocyte (RBC) will lose what and stop what
nuclei and multiplying
How long does erythropoiesis take for dogs, cows and birds
dog - 1 week
cow - 4 to 5 days
birds - 36 hours
what hormone controls the rate of erythropoesis
erythropoietin (EPO)
erythropoietin is produced primarily by what cells
cells of the kidney
the production of erythropoietin is regulated by what
blood oxygen levels in the kidney
what is the stimulus for increased erythropoietin production
hypoxia (low levels of oxygen in your body tissues)
in cases of severe anemia, what may be released
nucleated RBCs (NRBCs)
nucleated RBCs are immature stages of RBC that retain what
their nuclei
NRBCs are not fully mature so they aren’t as efficient even though they are producing what
some hemoglobin
the production of platelets
thrombopoiesis
large multinucleated cell that never leaves the bone marrow
megakaryocyte
what part of the megakaryocyte release platelets into peripheral blood
pieces of cytoplasm
platelets are also known as what
thrombocytes
thrombopoietin is produced by what
liver
formation of white blood cells
luekopoiesis
