Heme Function & Immunity Disorders

Question 1

Anemia results in deficient RBC count because of a lack of ______ elements or _____ ______ failure

Answer 1

Nutritional elements, bone marrow

Question 2

What are the 4 types of anemia?

Answer 2

Anemia of CHRONIC disease, pernicious/FOLATE deficiency anemia, IRON-deficiency, APLASTIC anemia

Question 3

This type of anemia results from impaired bone marrow/bone marrow depression

Answer 3

Aplastic anemia

Question 4

Which two types of anemia result from low RBC production?

Answer 4

Iron-deficiency anemia, pernicious/folate deficiency anemia

Question 5

Pernicious/folate deficiency anemia is also called what?

Answer 5

Megaloblastic anemias

Question 6

This is AKA an INCREASED RBC count and hematocrit greater than 50%

Answer 6

Polycythemia

Question 7

What are the two types of polycythemia?

Answer 7

Primary, secondary

Question 8

______ polycythemia is a neoplastic disease of the pluripotent cells of _____ ______

Answer 8

Primary, bone marrow

Question 9

______ polycythemia is the body’s normal response to hypoxia/hypoxemia

Answer 9

Secondary

Question 10

Mononucleosis is an infection of ______ ____ virus. You will have enlarged _____ _____

Answer 10

Epstein Barr virus, lymph nodes

Question 11

What are the four types of leukemia?

Answer 11

Acute lymphocytic, Acute myelogenous

Chronic lymphocytic, Chronic myelogenous

Question 12

This type of leukemia occurs mostly in children

Answer 12

Acute lymphocytic leukemia (ALL)

Question 13

This type of leukemia occurs mostly in older adults

Answer 13

Acute myelogenic leukemia (AML)

Question 14

Leukemia is a cancer of ________ ______ cells

Answer 14

Hematopoietic progenitor cells

Question 15

This is the MOST common type of leukemia, primarily with ___ cells

Answer 15

Chronic lymphocytic leukemia (CLL), B

Question 16

This type of leukemia will show infections, fever, weight loss; this cancer is _______

Answer 16

Chronic myelogenous leukemia (CML), terminal

Question 17

This type of lymphoma makes up 83% of cases; infection with HIV, EBV

Answer 17

NON-Hodgkin’s

Question 18

This type of lymphoma makes up 17% of cases; is an abnormal ____ ______ line

Answer 18

Hodgkin’s, B cell

Question 19

This is one of the most common types of blood cancers in the US!

Answer 19

Lymphoma

Question 20

There are MANY lymph nodes involved in this type of lymphoma

Answer 20

NON-Hodgkin’s

Question 21

There’s only a localized, single group of lymph nodes involved in this type of lymphoma

Answer 21

Hodgkin’s

Question 22

In multiple myeloma, ______ is released into the bloodstream. (Man goes to chiropractor for back pain, then is diagnosed with multiple myeloma!)

Answer 22

Calcium

Question 23

This is when abnormal B cells form tumors (produce abnormal antibodies)

Answer 23

Multiple myeloma

Question 24

What are some symptoms of multiple myeloma?

Answer 24

Immune depression, increased blood viscosity (from proteins), proteins infiltrate organs

Question 25

_________ disorders are an excessive or inappropriate activation of the _______ system

Answer 25

Hypersensitivity, immune

Question 26

What are the 4 types of hypersensitivity disorders?

Answer 26

I, II, III, IV

Question 27

Type I hypersensitivity disorder is an _____-mediated disorder. What’s an example?

Answer 27

IgE-mediated; environmental allergen

Question 28

Type II hypersensitivity disorder is an _____-mediated disorder. What’s an example?

Answer 28

Antibody-mediated; transfusion reaction

Question 29

Type III hypersensitivity disorder is a _____-mediated disorder.

Answer 29

Complement;

Question 30

Type IV hypersensitivity disorder is a _____-mediated disorder.

Answer 30

Cell

Question 31

This blood type is the universal DONOR, meaning they have ___ antigens on the surface

Answer 31

O- ; no antigens

Question 32

This blood type is the universal RECIPIENT, meaning they have ___ antigens on the surface

Answer 32

B+ ; all the antigens

Question 33

Type A blood would have __ antigens and __ antibodies

Answer 33

A, B

Question 34

Type B blood would have __ antigens and __ antibodies

Answer 34

B, A

Question 35

Type AB blood would have __ antigens and __ antibodies

Answer 35

AB, no antibodies

Question 36

What causes transfusion reactions?

Answer 36

ABO incompatibility; previous exposure to RBC content

Question 37

___ __ and _____ are needed to synthesize protein C to prevent excessive ________

Answer 37

Vit K, calcium, coagulation

Question 38

How does HIV affect cells?

Answer 38

HIV enters T cell, replicates inside it, then destroys it