Heme Function & Immunity Disorders Flashcards

(38 cards)

1
Q

Anemia results in deficient RBC count because of a lack of ______ elements or _____ ______ failure

A

Nutritional elements, bone marrow

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2
Q

What are the 4 types of anemia?

A

Anemia of CHRONIC disease, pernicious/FOLATE deficiency anemia, IRON-deficiency, APLASTIC anemia

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3
Q

This type of anemia results from impaired bone marrow/bone marrow depression

A

Aplastic anemia

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4
Q

Which two types of anemia result from low RBC production?

A

Iron-deficiency anemia, pernicious/folate deficiency anemia

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5
Q

Pernicious/folate deficiency anemia is also called what?

A

Megaloblastic anemias

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6
Q

This is AKA an INCREASED RBC count and hematocrit greater than 50%

A

Polycythemia

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7
Q

What are the two types of polycythemia?

A

Primary, secondary

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8
Q

______ polycythemia is a neoplastic disease of the pluripotent cells of _____ ______

A

Primary, bone marrow

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9
Q

______ polycythemia is the body’s normal response to hypoxia/hypoxemia

A

Secondary

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10
Q

Mononucleosis is an infection of ______ ____ virus. You will have enlarged _____ _____

A

Epstein Barr virus, lymph nodes

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11
Q

What are the four types of leukemia?

A

Acute lymphocytic, Acute myelogenous

Chronic lymphocytic, Chronic myelogenous

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12
Q

This type of leukemia occurs mostly in children

A

Acute lymphocytic leukemia (ALL)

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13
Q

This type of leukemia occurs mostly in older adults

A

Acute myelogenic leukemia (AML)

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14
Q

Leukemia is a cancer of ________ ______ cells

A

Hematopoietic progenitor cells

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15
Q

This is the MOST common type of leukemia, primarily with ___ cells

A

Chronic lymphocytic leukemia (CLL), B

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16
Q

This type of leukemia will show infections, fever, weight loss; this cancer is _______

A

Chronic myelogenous leukemia (CML), terminal

17
Q

This type of lymphoma makes up 83% of cases; infection with HIV, EBV

A

NON-Hodgkin’s

18
Q

This type of lymphoma makes up 17% of cases; is an abnormal ____ ______ line

A

Hodgkin’s, B cell

19
Q

This is one of the most common types of blood cancers in the US!

20
Q

There are MANY lymph nodes involved in this type of lymphoma

A

NON-Hodgkin’s

21
Q

There’s only a localized, single group of lymph nodes involved in this type of lymphoma

22
Q

In multiple myeloma, ______ is released into the bloodstream. (Man goes to chiropractor for back pain, then is diagnosed with multiple myeloma!)

23
Q

This is when abnormal B cells form tumors (produce abnormal antibodies)

A

Multiple myeloma

24
Q

What are some symptoms of multiple myeloma?

A

Immune depression, increased blood viscosity (from proteins), proteins infiltrate organs

25
_________ disorders are an excessive or inappropriate activation of the _______ system
Hypersensitivity, immune
26
What are the 4 types of hypersensitivity disorders?
I, II, III, IV
27
Type I hypersensitivity disorder is an _____-mediated disorder. What's an example?
IgE-mediated; environmental allergen
28
Type II hypersensitivity disorder is an _____-mediated disorder. What's an example?
Antibody-mediated; transfusion reaction
29
Type III hypersensitivity disorder is a _____-mediated disorder.
Complement;
30
Type IV hypersensitivity disorder is a _____-mediated disorder.
Cell
31
This blood type is the universal DONOR, meaning they have ___ antigens on the surface
O- ; no antigens
32
This blood type is the universal RECIPIENT, meaning they have ___ antigens on the surface
B+ ; all the antigens
33
Type A blood would have __ antigens and __ antibodies
A, B
34
Type B blood would have __ antigens and __ antibodies
B, A
35
Type AB blood would have __ antigens and __ antibodies
AB, no antibodies
36
What causes transfusion reactions?
ABO incompatibility; previous exposure to RBC content
37
___ __ and _____ are needed to synthesize protein C to prevent excessive ________
Vit K, calcium, coagulation
38
How does HIV affect cells?
HIV enters T cell, replicates inside it, then destroys it