hemodynamics Flashcards
(47 cards)
cardiac output
- best indicator of the condition of the hearts contractile (inotropic ability)
- volume of blood ejected by the heart in 1 min into the systemic circuit
- does not equate for differences in body size
normal CO
4-8 l/min
cardiac index
CO divided by an indiviuals body surface area
normal: 2.2-4
measured by PA cath
CO = ____ x ____
SV x HR
what is stroke volume
- volume of blod ejected by the left ventricle during each systole
- affected by three factors: preload, afterload, and contractility
normal SV
60-100 ml
what is preload
- The amount of stretch placed on cardiac muscle fibers just before systole.
- Volume of blood in the ventricle at the end of diastole
- Amount of myocardial stretch placed on the ventricular muscle fibers prior to systole application of Frank-Starling law of the heart
- Volume of blood creates a filling pressure
causes of elevated preload
- volume overload
- LV dysfunction
- RV dysfunction
- valvular defects
- cardiac tamponade
effects of increase preload on the heart
Increases stroke volume
Increases ventricular work
Increases myocardial oxygen requirements
assessment of right sided elevated preload
JVD
Edema
Hepato-jugular reflux(HJR)
assessment of left sided elevated preload
Orthopnea
Dyspnea
Cough
Crackles
S3
ways to reduce preload
- Drugs that directly reduce blood volume, e.g. diuretics
- Drugs that promote vasodilation, e.g.
Nitrates - Patient positioning (semi/high fowlers)
causes of decreased preload
Hypovolemia
Hemorrhage
Third spacing
Diuresis
Vasodilation
assessment findings of a decreased preload
Tachycardia/hypotension
Dry, cool skin
Dry mucous membranes
Poor skin turgor
Alteration in LOC
Decreased urine output/vital organ perfusion
right sided preload assessment
Right Ventricular End-Diastolic Pressure (RVEDP)
Right Atrial Pressure (RAP)
Central Venous Pressure (CVP)
left sided preload assessment
Left Ventricular End-Diastolic Pressure (LVEDP)
Pulmonary Artery Wedge Pressure (PCWP) aka
Pulmonary Artery Occlusive Pressure (PAOP)
Pulmonary Artery Diastolic Pressure (PADP
treatment to increase preload
volume administration
patient positioning - modified trendelenburg
what is afterload
Increased ventricular wall tension or stress during systolic ejection
Pressure that the ventricle has to pump against to eject blood into the circulation during systole.
Most critical factor determining afterload is vascular resistance.
- Systemic vascular resistance (SVR)
assessment of afterload
Mean arterial pressure (MAP) *not always correlated
Systemic Vascular Resistance (SVR)
- must have an invasive catheter to calculate SVR (must know cardiac output)
Pulmonary Vascular Resistance (PVR)
what causes an elevated afterload
Vasoconstriction (increased SVR)
Medications
- Alpha 1 agonists
Catecholamine release (compensatory mechanisms)
- Hypovolemia
- Pain
- Hypoxia
- Hypothermia
Hypertension
Increased aortic impedance
afterload reduction therapy
Vasodilator therapy
- Nitroprusside (Nipride)
- Calcium Channel Blockers (Nicardipine)
- ACE-Inhibitors (-pril)
- Angiotension Receptor Blockers (-sartan)
what causes a decreased afterload
Vasodilation (decreased SVR)
Inadequate aortic valve function
Inflammatory response
Hyperthermia
therapy to increase afterload
Vasopressor therapy e.g. Adrenergic stimulants
- Norepinephrine (Levophed)
- Phenylephrine (Neo-synephrine)
- Dopamine
- Vasopressin
what is contractility
The inotropic action of the heart muscle during systole or the force of each ventricular contraction