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Anemias e hemoglobinopatias > Hemoglobinopatias - Talassemias > Flashcards

Hemoglobinopatias - Talassemias Flashcards

1
Q

Qual a definição de talassemias?

A

Deficiência quantitativa de hemoglobina

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2
Q

Quais são os tipos de talassemias?

A

Alfa talassemia
Beta talassemia

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3
Q

Qual o mecanismo das talassemias?

A

Defeito na síntese de alfa ou beta globina
Acúmulo da cadeia normal
Eritropoese ineficaz
Hemólise extravascular

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4
Q

Como será o hemograma nas talassemias?

A

Anemia microcítica e hipocrômica
RDW normal

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5
Q

Como serão os reticulócitos nas talassemias?

A

Hiperproliferativa - há hemólise

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6
Q

Como será o perfil de ferro nas talassemias?

A

Ferritina elevada
IST elevado

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7
Q

Como será o esfregaço de sangue periférico nas talassemias?

A

Hemácias em alvo

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8
Q

Como serão as provas de hemólise nas talassemias?

A

Aumentadas - BI e LH
Haptoglobina consumida

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9
Q

Quais exames são específicos para diagnóstico de talassemia?

A

Eletroforese de Hb
Testes genéticos

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Anemias e hemoglobinopatias (12 decks)

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