Hemolytic Anemia

Question 1

What is hemolytic anemia?

Answer 1

Destruction or hemolysis of rbc at the rate that exceeds production

Question 2

Hemolytic anemia is caused by?

Answer 2

Problems with intrinsic or extrinsic to RBC

Question 3

Intrinstic hemolytic anemia is normally what?
And results defects in?

Answer 3

Which are usually hereditary and results from defects in RBC themselves

Question 4

More common are the acquired hemolytic anemias, in which this type of anemia the
RBC are ___?

Answer 4

Normal but external factors are causing damage

Question 5

What organ is the primary responsible for normal RBC destruction?

Answer 5

Spleen

Question 6

General manifestation of anemia
With specific manifestations including? (3)

Answer 6

Jaundice
Enlargement of spleen and liver

Question 7

Jaundice occurs because of the?

Answer 7

Increase RBC destruction that causes increase bilirubin levels

Question 8

The spleen and liver may enlarge from?

Answer 8

Hyperactivity which is due to macrophage phagocytosis of the defective RBC

Question 9

What a major focus treatment?

Answer 9

To maintain renal function

Question 10

What is the reason why we want to maintain renal function and cause ?

Answer 10

Hemoglobin from hemolized RBC are filtered through the kidneys
Which can cause acute tubular necrosis