Hemostasis Flashcards
(7 cards)
1
Q
Hemostasis
A
It a dynamic process which
Plt and blood vessels wall plays key roles here
2
Q
Platlet Overview
Major Regulator PLt Formation
A
- ***Thrhombopoietin = Formatio *
**- Hormone play major roel in Plt formation which synthesis in liver - ***Megakaryocytes : Released **
- Releassed : Where Plt released under influece of blood flow and capiallary sinuses
***Adhesion to von Willebrand factor (VWF) & Collagen *
**- Becomes Activated
- Plt becoms activated upon adhesions to VWF and collagen
3
Q
what is
Adhesio to von Willebrand Factor
VWF
A
Protein preset in both plasma ad in extra cellular matric that plays key role in coagulation System
4
Q
Activated Platelet Surface
A
Major physiologic site for coagulation factor activation
5
Q
Platlets Normal Characteristics
A
- Normal Platelet Count:
150,00 to 450,000 - Platlets circulate in Average Lifespan: 7 to 10 days
- 33% (3rd of ) platlets reside in spleen
Decreased #PLT — SPlenomegaly
- Rarely <40,000
- If it doese - it to something else
6
Q
Spleen Function
A
**Plays roles in body
- act as filter for blood
- part of immune system fight infection
- Act as center for recycling of old RBC
- Storage of RBC and Plt
*
7
Q
A
