Hemostatic Agents Flashcards
What is the source of oxidized regenerated cellulose?
Plant
What is the brand name of oxidized regenerated cellulose?
Surgicel
What is the MOA of Surgicel?
Activates extrinsic pathway
Scaffold for platelet aggregation
What is the source of microporous polysaccharide spheres?
Potato starch
What is the brand name of microporous polysaccharide spheres?
Arista
What is the MOA of Arista?
Absorbs water > platelet/coagulant concentration
What is the source of gelatin matrix?
Porcine
What is the brand name of gelatin matrix?
Surgifoam
Gelfoam
What is the MOA of Surgifoam/Gelfoam?
Provides mechanical hemostasis via increased weight d/t blood/fluid absorption
What is the source of microfibrillar collagen?
Bovine
What is the brand name of microfibrillar collagen?
Avitene
What is the MOA of Avitene?
Activates extrinsic pathway
Scaffold for platelet aggregation
What is the source of topical thrombin?
Bovine
Recombinant human
What is the brand name of topical thrombin?
Floseal
Surgiflo
What is the MOA of Floseal/Surgiflo?
Converts fibrinogen > fibrin
What is the source of fibrin sealant
Human plasma
What is the brand name of fibrin sealant?
Tisseel
What is the MOA of Tisseel?
Combines thrombin + fibrin to form a clot
What is the only topical hemostatic agent approved for arterial bleeding?
Arista
