Hepatitis

Question 1

Systemic symptoms of hepatitis

Answer 1

• N/V
• jaundice
• muscle/joint pain
• fever
• loss of appetite

Question 2

Urine changes in hepatitis

Answer 2

Darker

Question 3

Stool colour changes in hepatitis

Answer 3

Pale

Question 4

Pain location in hepatitis

Answer 4

Right upper quadrant

Question 5

Hep A and D is found in

Answer 5

Stool

Question 6

Hep B is found in

Answer 6

Blood/semen

Question 7

Hep C is found in

Answer 7

Blood

Question 8

Hep E is found in

Answer 8

Raw mEEt

Question 9

HAV antibodies

Answer 9

• IgM

- IgG

Question 10

LFT in hepatitis

Answer 10

• raise AST
• raised ALT
• raised ALP (less of a rise)
• raised bilirubin

Question 11

Most common hep worldwide that is not too common in UK

Answer 11

Hep A

Question 12

fAEco-oral hep viruses

Answer 12

Hep A & E

Question 13

Hep A extra presentations

Answer 13

• cholestasis

- moderate hepatomegaly

Question 14

Hep A is self limiting within how many months

Answer 14

1-3

Question 15

Mx Hep A

Answer 15

Basic analgesia

Question 16

Notifiable Hep viruses

Answer 16

All

Question 17

Hep viruses that have vaccinations

Answer 17

A & B

Question 18

Which hep virus is the ONLY DNA virus

Answer 18

B

Question 19

Transmission of hep B

Answer 19

• direct contact (blood/bodily fluids)

- vertical transmission

Question 20

Recovery period from hep B

Answer 20

1-2 months

Question 21

How many chronic hep patients carry B

Answer 21

10%

Question 22

How many spaced out doses of hep B vaccine are given

Answer 22

3

Question 23

Summarise management algorithm for hep viruses

Answer 23

• low screening threshold
• screen for other viruses
• refer to specialist
• notify public health
• stop smoking/alcohol
• educate
• fibroscan/USS
• antivirals
• transplantation

Question 24

Fibroscan detects

Answer 24

Cirrhosis

Question 25

USS detects

Answer 25

Heptocellular carcinoma

Question 26

Visit hep B diagram

Answer 26

To make sure u understand Abs and Ags

Question 27

Presence of surface antibody (HBsAb) indicates (2)

Answer 27

- vaccination | - infection

Question 28

Presence of HBeAb indicates (released during replication)

Answer 28

Been thru active phase | + HBeAb —> + infective

Question 29

Presence of HBcAb and high IgM indicate

Answer 29

Active infection

Question 30

Presence of HBcAb and low IgM indicate

Answer 30

Chronic inflammation

Question 31

Presence of HBcAb and IgG indicate

Answer 31

Past infections

Question 32

Hep C transmission

Answer 32

- blood | - bodily fluids

Question 33

Cure for hep C

Answer 33

Direct acting antivirals

Question 34

Full recovery in hep C

Answer 34

1 in 4

Question 35

Which antigen on which hep does hep D attach to

Answer 35

HBsAg

Question 36

Hep D tx

Answer 36

None

Question 37

Why are female in 40s/50 vulnerable to type 1 autoimmune hepatitis

Answer 37

Menopause

Question 38

More severe autoimmune hepatitis

Answer 38

Type 2

Question 39

Epi type 2 hepatitis

Answer 39

Children

Question 40

Type 1 autoimmune hepatitis Abs

Answer 40

- ANA - anti-actin - anti-SLA/LA

Question 41

Type 2 autoimmune hepatitis Abs

Answer 41

- Anti-LKM1 (liver, kidney, microsome | - Anti- LC1 (liver, cytosol)

Question 42

1st line for autoimmune hepatitis

Answer 42

Prednisolone

Question 43

2nd line for autoimmune hepatitis

Answer 43

Azathioprine

Question 44

antibodies found in autoimmune hepatitis

Answer 44

anti smooth muscle antibodies