Hepatitis Flashcards
(32 cards)
Causes of hepatitis
Alcoholic hepatitis, NAFLD, viral, autoimmune, drug induced
Presentation of hepatitis
Abdominal pain, fatigue, pruritis, muscle and joint aches, nausea and vomiting, jaundice, fever
How is hep A transmitted
Faecal-oral route usually by contaminated water or food
Presentation of hep A
Nausea, vomiting, anorexia, jaundice, cholestasis, dark urine, pale stools, hepatomegaly
Management of hep A
Usually resolves in 1-3 months so analgesia only
What type of virus is hep A
RNA virus
What type of virus is hep B
DNA virus
How is hep B transmitted
Direct contact with blood or bodily fluids
Prognosis of hep B
Most recover in 2 months, but 10% go on to be chronic hep B carrier
What does HBsAg imply
Surface antigen - active infection
What does HBeAg imply
E antigen - marker of viral replication and implies high infectivity
What does HBcAb imply
Core antibodies - past or current infection
What does HBsAb imply
Surface antibody - implies vaccination, past or current infection
What does the HBV DNA imply
Hepatitis B virus DNa which is a direct count of the viral load
Management of hep B
Screen for other blood born viruses, refer for specialist management, stop smoking and alcohol, test for complications, antivirals, informing contacts
Complications of Hep B
Cirrhosis and hepatocellular carcinoma
What type of virus is hep C
RNA virus
How is hep C transmitted
Blood and bodily fluids
How can hep C be treated
Direct acting antivirals tailored to the specific genotype, successful in 90%
What type of virus is hep D and E
RNA virus
Which viral hepatitis’ need to be notified to public health
All of them
How is hep D spread
It can only survive in patients who also have hepatitis B
Effect of hep D
Increases complications and disease severity of hep B and there is no specific treatment
How is hep E spread
Faecal-oral route
