Hepatitis Flashcards

1
Q

hepatitis E association

A

uncooked boar/swine/pig ingestion

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2
Q

HEV outbreaks are linked to

A

water contamination in Asia and Africa

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3
Q

treatment of chronic Hep E

A

ribavirin

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4
Q

treatment of chronic Hep E in pregnant women

A

none, can’t give them ribavirin

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5
Q

diagnosis of Hep E

A

RNA PCR
IgM anti HEV

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6
Q

most common cause of acute hepatitis in US

A

Hep A

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7
Q

fulminant hepatitis with chronic Hep C

A

hep A

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8
Q

when to use IG as post exposure ppx Hep A

A

> 40 years or immunosuppressed

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9
Q

when can you see liver tox from augmentin

A

often after stopping it

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10
Q

what type of genotype in HEV in US

A

Genotype 3

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11
Q

HCV association in which population

A

HIV MSM

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12
Q

blistering lesions in sun exposed areas, exacerbated by alcohol use

A

porphyria cutanea tarda

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13
Q

three skin manifestations of HCV

A

PCT
lichen Plans
cryoglobulin vasculitis

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14
Q

HBV skin manifestation

A

polyarteritis nodosa

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15
Q

HCV screening

A

one AB test aged 18 to 79 years

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16
Q

who needs HCV resistance testing treatment naive

A

Genotype 1a and using elbasvir/grazoprevir
Genotype 3 AND cirrhosis using sofosbuvir/velpatasvir

17
Q

who needs HCV resistance testing treatment experienced

A

1a and using ledipasvir/sofosbuvir
Genotype 3 and using sofosbuvir/velpatasvir

18
Q

Chronic HBV on treatment for HCV
If HBsAg positive

A

treat per HBV guidelines

19
Q

Chronic HBV on treatment for HCV
Anti-HBc positive

A

monitor

20
Q

pangenotypic HCV regimens

A

Glecaprevir/pibrentasvir
Sof/Vel

21
Q

which HCV regimen is approved for ESRD

A

Glec/Pib
Sof/Vel
Sof/Led

22
Q

which HCV regimen to avoid on patient taking darunavir

A

Glec/pib
(double protease inhibitors)

23
Q

indication for treatment in HBsAg positive pregnant women

A

HBV DNA > 200,000 in third trimester

24
Q

treatment HBV GFR <10 no HD

A

entecavir

25
Q

Three situations for prophylaxis in CHB

A

Rituximab
high dose prednisone
BM transplant

26
Q

Patients who are HBsAg positive undergoing immunosuppression

A

prophylaxis always needed no matter what immunosuppressive they get

27
Q

If patient is anti-HBc positive but sAg negative when to given prophylaxis

A

rituximab, high dose prednisone or BM transplant (high risk exposures/IS)

28
Q

isolated HBcore vaccination

A

give one dose, if titer >10 then stop
if titer <10 then give second dose

29
Q

PEP for infants of HBsAg mothers

A

immediate vaccination and HBIG