STIs Flashcards

1
Q

Painless genital lesions

A

syphilis, LGV, Granuloma Inguinale

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1
Q

painful genital lesions

A

HSV, Haemophilus Ducreyi

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2
Q

describe appearance of HSV lesions

A

superficial, vesicular, erythematous base

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3
Q

Best diagnosis of HSV lesions

A

PCR

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4
Q

What to test if there is concern for HSV resistance

A

culture to get sensitivities

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5
Q

describe syphilis lesions

A

single, well circumscribed with heaped up borders and clean base

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6
Q

describe chancroid lesions

A

indurated, tender, suppurative inguinal LAD with kissing lesions n thigh

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7
Q

describe LGV lesions

A

ulcer, painful LAD, groove sign

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8
Q

proctitis can be seen with

A

LGV, HSV, MPOX

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9
Q

describe granuloma inguinale lesions

A

progressive serpiginous without LAD, beefy red lesions that bleed when biopsied

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10
Q

what is the drug of choice to treat syphilis in pregnancy

A

penicillin, no alternatives

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11
Q

features of primary syphilis

A

chancre, LAD

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12
Q

features of secondary syphilis

A

systemic symptoms, fever, malaise, sore throat, rash, LAD

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13
Q

features of syphilis hepatitis on labs

A

alk phos is very high compared to AST and ALT

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14
Q

what test to do if a patient is diagnosed with cardiovascular syphilis

A

need LP- they will have asymptomatic neurosyphilis

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15
Q

alternative therapy of early syphilis

A

doxycycline x 14 d

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16
Q

alternative therapy of late latent syphilis

A

doxycycline x 4 weeks

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17
Q

complication of J-H reaction in pregnancy

A

can induce early labor

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18
Q

alternative treatments for neurosyphilis

A

procaine penicillin IM plus probenecid for 10-14 d
Ceftriaxone IV or IM x 10-14 d

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19
Q

syphilis screening in pregnancy

A

during 1st trimester
screen high risk in 28 w and at the time of delivery

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20
Q

special circumstance for syphilis screening in pregnancy

A

if they have stillbirth after 20 weeks

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21
Q

indications for c/section with HSV

A

active lesions or prodromal symptoms

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22
Q

HSV suppressive therapy indicated in HIV

A

with CD4 < 200 if they have history of HSV and they are going to start ART- x 6 months

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23
Q

how to diagnose HSV in asymptomatic patients

A

Glycoprotein G EIA assays

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24
Q

Gg2 +

A

genital herpes

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25
Q

Gg1+

A

either oral or genital- can’t tell difference

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26
Q

when to use HSV IgM

A

never

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27
Q

how to diagnose chancroid

A

culture

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28
Q

treatment of chancroid

A

azithromycin 1g PO x 1 dose or CTX 250 mg IM x 1 dose

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29
Q

how to diagnose GI

A

biopsy

30
Q

what stain to use for GI diagnosis

A

wright giemsa stain

31
Q

feature of GI pathology

A

Donovan bodies within macrophages

32
Q

treatment of GI

A

Doxycycline x 3 weeks or resolution of lesion
Azithromycin x 3 weeks
TMP-SMXw

33
Q

who should be tested for m. genitalium

A

men with persistent urethritis or epididymitis
women with persistent cervicitis or PID
men or women with persistent proctitis symptoms
*anyone who doesn’t respond to initial therapy

34
Q

treatment of choice for m. genitalium

A

moxifloxacin 400 mg qd 7-14 days

35
Q

treatment of trich in women

A

metronidazole x 1 week or tinidazole 2g PO x 1

36
Q

treatment of trich in men

A

metronidazole 2g x 1 dose or tinidazole 2g x 1

37
Q

screening of trich in HIV women

A

annually

38
Q

prefer treatment of trich in women

A

1 week of metronidazole

39
Q

options for treatment failure trich with metronidazole

A

tinidazole 2g po x 1
metronidazole 2g PO x 5d
tinidazole 2g po qd x 5d

40
Q

do partners of BV infection need to be treated?

A

no

41
Q

pH in BV

A

> 4.5

42
Q

positive whiff test in BV

A

amine odor with KOH

43
Q

treatment of BV

A

metronidazole 500 mg BID x 7d
Clindamycin 300 mg PO TID x 7d
or topical metronidazole or clindamycin

44
Q

screening of BV during pregnancy

A

only screen symptomatic patients

45
Q

criteria for hospitalization in PID

A

pregnant
TOA
can’t rule out appendicitis
didn’t respond to PO therapy
N/V, fever/systemically ill
no reliable outpatient therapy

46
Q

treatment of outpatient PID

A

CTX 500 mg x 1 IM
Doxy 100 mg BID.x 14d
Metronidazole 500 mg BID x 14d

47
Q

Inpatient therapy of PID

A

Cefotetan 2g BID or Cefoxitin 2g q6h plus Doxycycline 100 mg BID

48
Q

treatment of epididymitis in young people

A

CTX 500 mg x 1 and Doxy 100 mg BID x 10 d

49
Q

who should be screened for chlamydia

A

sexually active women 25 years or younger and older women with risk factors (multiple sex partners)

50
Q

post infectious complication of chlamydia

A

reactive/reiter’s arthritis

51
Q

preferred test for chlamydia dx in women

A

vaginal swab NAAT

52
Q

preferred test for chlamydia test in men

A

first catch urine NAAT

53
Q

treatment of chlamydia in pregnancy

A

azithromycin

54
Q

when to screen treated persons for chlamydia

A

3 months after treatment, rates of reinfection are high

55
Q

treatment of choice in gonorrhea

A

ceftriaxone 500 mg IM x 1

56
Q

treatment of pharyngeal GC

A

only CTX

57
Q

follow up test for pharyngeal GC

A

need test of cure 7-14 d after therapy

58
Q

treatment of GC conjunctivitis

A

1g CTX

59
Q

complications of DGI

A

hepatitis
endocarditis
meningitis

60
Q

risk factor for DGI

A

terminal complement deficiency

61
Q

second line treatment for urogenital or rectal GC

A

cefixime 800 mg x 1
gentamicin 5 mg/kg x 1 IM + 2g azithromycin

62
Q

Differential if person fails doxycycline for treatment of NGU

A

reinfection
mycoplasma genitalium
trichomonad vaginalis
HSV

63
Q

trichomonas can be seen in what population? less common in what population

A

MSW
MSM

64
Q

HPV vaccines during pregnancy?

A

don’t give, can just pick up where you left off after they deliver

65
Q

molluscum treatment

A

curettage, cryotherapy, topical cidofovir

66
Q

pediculosis pubis, if nits are on the upper shaft, treatment?

A

no, old infection, no need for pretreatment

67
Q

treatment of pediculosis pubis
if treatment failure

A

permethrin cream or pyrethrins topical
malathion lotion or ivermectin if treatment failure

68
Q

lindane in crabs?

A

don’t use
associated with seizures and aplastic anemia

69
Q

treatment of scabies

A

permethrin cream
ivermectin and day 1 and 14

70
Q

crusted scabies or Norwegian scabies seen in what population

A

HIV, immunocompromised

71
Q

treatment of crusted/norwegian scabies

A

ivermectin on days 1 ,15, 19

72
Q
A