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Hepatitis Flashcards

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0
Q

genus of picornaviridae

A

hepatovirus

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1
Q

cause of hepa A

A

picornavirus

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2
Q

itsura ng picornavirus

A

spherical particle w/ ssRNA

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3
Q

does hepa A cause chronic live disease

A

no

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4
Q

hepa A has ____ serotypes ______ genotypes

A

1;7

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5
Q

how to destroy picornavirus

A 
autoclave
boiling
dry heat
UV
formalin
chlorine
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6
Q

percent of hepa A among all hepa

A

40%

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7
Q

percentage of complete recovery

A

99%

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8
Q

serological findings in lab diagnosis for hepa A

A

HAV
anti HAV
IgM anti HAV

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9
Q

what serological finding in hepa A indicates recent infection

A

IgM antiHAV

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10
Q

cause of hepa B

A

hepadnavirus

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11
Q

MOT of hepa A

A

fecal oral route

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12
Q

MOT of hepa B

A

parenterally

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13
Q

____ of hepa B develops chronic liver dis

A

5-10%

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14
Q

morphologic forms of hepa B

A

small spherical
tubular or filamentous
large spherical (Dane particle)

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15
Q

composition of Dane particle Hepa B

A

HBsAg envelop

HBcAg core

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16
Q

phenotypes of HBsAg

A

ayw
adw
ayr
adr

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17
Q

major risk factor for hepa B

A

sexual promiscuity

drug abuse

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18
Q

1st sign of recovery from hepa B

A

renewed appetite

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19
Q

clinical syndromes of Hepa B

A

acute
chronic
primary Hepatocellular carcinoma

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20
Q

pathology of hepa B

A

spotty parenchymal cell degen
diffuse lobular inflammation
disruption of liver cell cords

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21
Q

screening for hepaB

A

agglutination test

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22
Q

confirmatory for hepa B

A

ELISA

PCR

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23
Q

sero of hepa B

A 
HBV
HBsAg
HBeAg
HBcAg
anti HBs
anti HBe
anti HBc
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24
hepa b sero that indicates viral replication
HBeAg
25
hepa B sero that indicates past infection
anti HBsAg | anti HBcAg
26
trisls for hepa B tx
interferon adenine arabinoside steroids azathioprine
27
hepaB immune globulin is given to
post exposure prophylaxis of + mother | mucosal xposure
28
cause of hepaC
hepacivirus
29
hepacivirus is under
flaviviridae
30
major cause of post transfusion hepa
hepa C
31
_____ of HCV patients develop chronic illnesses
70-90%
32
MOT of hepaC
parenteral | sexual
33
____ is not protective
anti HCV
34
form of hepa C that often leads to cirrhosis
chronic form
35
markers of HepaC
HCV | antiHCV
36
smallest known human pathogen
hepa D
37
itsura ng hepa D
HDAg surrounded by HbsAg envelop
38
hepa D infects only those with
underlying HBV inf
39
markers of hepa D
HDV anti HDV HDAg
40
_____ is protective against delta infection
hepa B vaccine
41
Mot of hepa F
fecal oral | water borne
42
where was hepa F found
one experimental monkey
43
genome of hepa F
dsDNA
44
only double stranded na ekek
reovirus
45
not know ro cause human disease
reovirus
46
causes inapparent infections
reovirus
47
most important cause of infantile diarrhea
rotavirus
48
single +, naked segmented
rotavirus
49
MOT of rotavirus
fecal oral route
50
incubation period of rotavirus
1-3days
51
most frequent pathogen under rotavirus
group A
52
viral excretion of rotavirus in stool persists until
50 days
53
rotavirus affects the
vili of small int
54
rotavirus diarrhea is caused by
impaired sodium and glucose absorption
55
host response to rotavirus
IgM > IgG and secretory IgA
56
lab diagnosis for rotavirus
ELISA IEM LPA PCR
57
single +, naked icosahedral
calicivirus
58
star of David appearance
calicivirus
59
why star of David
bcoz of 5peplomers
60
incubation for calici
24-48hrs
61
causes usually nonbloody non,ucoid stool
norwalk virus
62
first incidence of norwalk vrus
norwalk, ohio
63
lab diagnosis for norwalk virus
RT-PCR ELISA IEM
64
is there vaccine for norwalk virus
none
65
how dies pironaviridae emter
oropharynx intestinal mucosa upper RT
66
______ are limited to RT
rhinovirus
67
infections by picornaviridae are usually
asymptomatic
68
prototype of picornaviridae
poliovirus
69
receptor recognized by poliovirus are found in
``` anterior horn cells of spinal cord dorsal motor ganglia motor neurons skel muscle lymphoid cells ```
70
MOT of picornaviridae
fecal oral
71
outcomes from poliovirus
asymptomatic illness abortive poliomyelitis nonparalytic paralytic
72
types of paralytic poliomyelitis
paralytic poliomyelitis bulbar poliomye postpolio syndrome
73
viruses associated with herpangina
coxsackie A
74
viruses assoc with pleurodynia and myocarditis
coxsackie B
75
vesicular lesions arecalled
herpangina
76
hand foot mouth disease caused by
cox A16
77
other term for pleurodynia
bornholm disease | devil's grip
78
acute febrile illness accompanied by headache and signs kf meningeal irritation
viral (aseptic) meningitis
79
feevr and rash may occur in px with
echo | cox
80
CSF results from polio or enetero shows
lymphocytic pleocytosis
81
CSF glucose is normal or slightly low in
viral meningitis
82
where is piliovirus isolated
phrynx
83
where does poliovirus grow well
monkey kidney tissue culture
84
serological finding in poliovirus inf
IgM | 4-fold increase in Ab titer
85
types of polio vaccine
OPV | IPV
86
which vaccine is made from live attenuated poliovirus
OPV
87
which vaccine is cheaper and commonly used
OPV

MycoViro (9 decks)

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